Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,764 recruiting studies in this area right now.
By phase
- Not applicable3,111
- Phase 4251
- Phase 2144
- Phase 3104
- Phase 197
- Phase 2/Phase 335
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University97
- Cairo University62
- Beijing Tiantan Hospital34
- Ain Shams University32
- Tanta University30
- Foundation University Islamabad26
- Mayo Clinic26
- Stanford University24
- VA Office of Research and Development22
- Hacettepe University20
Where studies are running
- California158
- New York80
- Massachusetts68
- Florida65
- Texas52
- Ohio48
- Maryland42
- Minnesota41
- Illinois38
- North Carolina38
Recruiting studies3,763 total
- NCT07591324Recruiting
3D-Printed vs. Traditional Space Holders for Kids' Teeth
This study compares two types of dental devices that hold space in a child's mouth after baby molars fall out early. The research tests whether a newer 3D-printed version works as well as or better than the traditional wire-based device.
Ismailia, Ismailia GovernorateAges 7–9 - NCT07591584Recruiting
Digestive Enzyme Blend for Bloating and Gas Relief
This study tests whether a daily digestive enzyme supplement designed to break down certain hard-to-digest foods can reduce bloating and belly pain. You'll use a smartphone app to track your symptoms over several weeks to see if the enzyme helps.
Los Angeles, CaliforniaAges 18 years+ - NCT07593183Recruiting
Spine exercises and telehealth for postpartum lower back pain
This trial tests whether guided spine-strengthening exercises (done at home via video or in-person) can reduce lower back pain and improve posture in women recovering from childbirth. Researchers measure the curve of your lower spine and track pain relief over time.
Islamabad, Punjab ProvinceAges 20–40 - NCT07595718Recruiting
AI Study of Disease Patterns and Health Data
This research uses artificial intelligence to analyze health information from adults to better understand and predict when major diseases like diabetes, heart disease, and cancer might develop. Your participation could help scientists discover new patterns that improve early detection.
Seoul, Seoul Special CityAges 30–60 - NCT07598474Recruiting
Pregabalin and Movement Therapy for Knee Osteoarthritis Pain
This trial tests whether a nerve pain medication called pregabalin, applied through ultrasound waves to your knee, combined with gentle movement exercises, can reduce pain in advanced knee osteoarthritis. You'll attend 16 treatment sessions over 4 weeks to see if this combination helps.
Faisalābad, Punjab ProvinceAges 40–60 - NCT07602595Recruiting
Understanding pain after childhood rheumatic disease or surgery
This study helps researchers learn how young adults (ages 14–26) who had rheumatic disease or orthopedic surgery as children experience pain over time. By understanding your story, the study may help doctors better support others facing similar challenges.
Cincinnati, OhioAges 14–26 - NCT07603609Recruiting
Balance Platform Training for Chronic Low Back Pain
This study tests whether training on a special moving balance platform can help reduce chronic low back pain. You'll practice exercises designed to improve your balance and core stability over several weeks.
AnkaraAges 18–55 - NCT07603674Recruiting
Personalized Primary Care for Muscle and Joint Pain
This trial tests whether tailoring musculoskeletal pain treatment to each patient's unique needs in primary care works better than standard care. You'll work with your regular doctor to find the approach that works best for your specific pain.
StockholmAges 18 years+ - NCT07603960Recruiting
Cold therapy to ease endometriosis pelvic pain
This study tests whether exposing your whole body to very cold air (below freezing) can reduce chronic pelvic pain from endometriosis and improve your quality of life. Endometriosis is a condition where tissue similar to the uterine lining grows outside the uterus, often causing pain.
Edinburgh, ScotlandAges 16 years+ - NCT07604376Recruiting
Nerve Block Pain Relief After Cesarean Delivery
This study tests whether a nerve-numbing injection in the abdomen helps reduce pain after a cesarean (C-section) delivery. The injection uses a local anesthetic to numb the area around your surgical wound, potentially reducing pain and the need for stronger pain medicines after surgery.
Târgu Mureş, Mureș CountyAges 18 years+ - NCT07605754Recruiting
Nerve Surgery Results for Pain After Amputation
This study evaluates how well nerve surgery works for patients with severe, persistent pain in the area where a limb was amputated. Researchers will review outcomes to understand if this surgical approach helps reduce pain that hasn't responded to other treatments.
Leiden, South HollandAges 18 years+ - NCT07610408Recruiting
Pain Relief Methods After Chest Surgery Nerve Block Wears Off
This study compares different intravenous (IV) pain medications given after a regional anesthetic nerve block stops working in patients having minimally invasive chest surgery. The goal is to find the most effective pain management strategy for recovery.
Ankara, KeçiörenAges 18–80 - NCT07612761Recruiting
Pain Relief Methods for Hip Fracture Surgery
This trial compares two different nerve-blocking techniques to help manage pain after hip fracture surgery. Both methods numb the area around your hip to reduce pain and may help you recover better.
Istanbul, IstanbulAges 18 years+ - NCT07614945Recruiting
Reflexology for Pain and Sleep in Fibromyalgia
This study tests whether reflexology—a massage technique applied to specific points on the feet and hands—can help reduce pain and improve sleep in women with fibromyalgia. Fibromyalgia causes widespread muscle pain and sleep problems, and this trial explores whether reflexology might offer relief.
Al Mansurah, Dakahlia GovernorateAges 18–65 - NCT07615725Recruiting
Dry Needling for Lower Leg Pain in Multiple Sclerosis
This study tests whether dry needling—a technique using thin needles to treat muscle pain—can help reduce lower leg pain in people with multiple sclerosis. Researchers want to see if this treatment can safely improve pain and function.
Tampa, FloridaAges 18–80 - NCT07615816Recruiting
Medical massage therapy for active-duty service members with recent lower back pain
This study tests whether massage therapy can help active-duty service members who have had lower back pain for 1–3 months. Researchers want to see if massage reduces pain and improves function.
Joint Base Lewis McChord, WashingtonAges 18–64 - NCT07616648Recruiting
How Opioid Pain Drugs Affect Sleep and Mood in Cancer Patients
This study examines how opioid medications (strong pain relievers) impact sleep quality and emotional well-being in cancer patients with moderate to severe pain. Researchers will track your sleep patterns and mood to better understand these side effects.
HangzhouAges 18–75 - NCT07619651Recruiting
Pain relief methods after hypospadias repair in young boys
This trial compares two different numbing techniques to help manage pain after hypospadias surgery (a procedure to correct the urinary opening in boys). The goal is to find which method works better and is safer for young children.
KayseriAges 6 months–7 years - NCT07620119Recruiting
AI-assisted heart attack diagnosis in patients with LBBB
This study tests whether artificial intelligence can help doctors more accurately diagnose heart attacks in patients who have a specific heart rhythm pattern called Left Bundle Branch Block (LBBB). The goal is to improve emergency care by reducing delays in identifying who needs urgent treatment.
Konya, KaratayAges 18 years+ - NCT07624136Recruiting
Kinesio Taping for Shoulder Flexibility and Range of Motion
This study tests whether a special athletic tape (Kinesio tape) applied to your lower back and shoulder area can improve flexibility and reduce shoulder pain in people with chronic shoulder impingement syndrome—a condition where shoulder structures get pinched, causing long-term pain and stiffness.
Ankara, AltindagAges 20–40 - NCT07626346Recruiting
Pain relief medication added to shoulder surgery nerve block
This trial tests whether adding a medication called dexmedetomidine to a numbing injection around shoulder nerves can improve pain control after laparoscopic shoulder surgery. The goal is to see if this combination works better than the numbing medication alone.
CairoAges 18–65 - NCT07627542Recruiting
Smartphone use and neck posture in arthritis patients
This study looks at how much time people with rheumatoid arthritis or ankylosing spondylitis spend on smartphones and how it affects their neck posture, balance, and disability. Understanding this connection may help doctors give better advice about phone use and neck health.
Konya, MeramAges 18–65 - NCT07628348Recruiting
Physical therapy for neck pain from disc herniation
This study tests a physical therapy technique called DRT (Diaphragmatic Respiration Training) to help patients with neck pain, tingling in the arm, and limited neck movement caused by a slipped disc in the neck. The goal is to improve neck flexibility, reduce pain, and expand the chest.
Lahore, Punjab ProvinceAges 35–55 - NCT07628387Recruiting
Exercise Types for Restless Legs in Pregnancy
This study compares two types of exercise—aerobic (heart-pumping) and muscle relaxation—to help pregnant women with restless leg syndrome sleep better and feel less tired. Restless leg syndrome causes uncomfortable sensations in the legs, especially at night, which disrupts sleep during pregnancy.
Lahore, Punjab ProvinceAges 20–40
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,764 recruiting pain medicine studies from the U.S. registry right now, out of 6,842 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.