Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,764 recruiting studies in this area right now.
By phase
- Not applicable3,111
- Phase 4251
- Phase 2144
- Phase 3104
- Phase 197
- Phase 2/Phase 335
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University97
- Cairo University62
- Beijing Tiantan Hospital34
- Ain Shams University32
- Tanta University30
- Foundation University Islamabad26
- Mayo Clinic26
- Stanford University24
- VA Office of Research and Development22
- Hacettepe University20
Where studies are running
- California158
- New York80
- Massachusetts68
- Florida65
- Texas52
- Ohio48
- Maryland42
- Minnesota41
- Illinois38
- North Carolina38
Recruiting studies3,763 total
- NCT07628452Recruiting
Aerobic exercise versus relaxation for period pain
This study compares two natural approaches—regular aerobic exercise and progressive muscle relaxation—to help reduce painful periods. You'll be assigned to one approach and tracked to see which works better for mild to moderate period cramping.
Okāra, Punjab ProvinceAges 17–24 - NCT07629141Recruiting
Muscle Position and Dry Needling for Neck Pain
This study tests whether the position of your neck muscle affects how well dry needling (inserting thin needles into tight muscle knots) relieves chronic neck pain. Dry needling may help reduce pain by relaxing tense muscles.
Alcalá de Henares, MadridAges 18–80 - NCT07630142Recruiting
Massage methods for chronic neck pain: an imaging study
This trial compares two types of massage—long, gentle strokes versus a handheld massager—for relieving long-lasting neck pain. Ultrasound imaging will be used to see how the muscles respond.
PoznanAges 18–60 - NCT07630337Recruiting
Cryotherapy to reduce pain medication after knee replacement
This study tests whether applying cold therapy (cryotherapy) after knee replacement surgery helps patients need fewer opioid pain medications than standard care alone. If cryotherapy works, it could help you manage pain more safely after surgery.
Buenos Aires, Buenos AiresAges 18 years+ - NCT07632612Recruiting
Nerve-Stretching Techniques for Sciatica Pain Relief
This trial compares two hands-on physical therapy techniques—one that stretches the sciatic nerve and one that moves it gently—to see which works better for sciatica pain that has lasted several months. You'll receive one of these treatments to help reduce leg pain and improve your ability to walk and move.
Rawalpindi, Punjab ProvinceAges 20–50 - NCT07632820RecruitingPhase 4
Nerve Block vs. Injection for Upper Back Muscle Pain
This study compares two ways to treat chronic muscle pain in the upper back: a nerve block (numbing injection near the spine) and trigger point injections (shots directly into painful muscle knots). The goal is to see which approach works better for long-lasting relief.
Jacksonville, FloridaAges 18–80 - NCT07633444Recruiting
Ear Stimulation to Reduce Pain After Abdominal Surgery
This study tests whether mild electrical stimulation applied to your ear can reduce pain and the need for pain medication after abdominal or urologic surgery. Researchers will try different stimulation frequencies to find what works best.
Salvador, Estado de BahiaAges 18–59 - NCT07633730Recruiting
Nerve Block for Back Pain in Ankylosing Spondylitis
This study tests whether a nerve-blocking injection in the back muscles can relieve persistent back pain in people with ankylosing spondylitis (a condition causing spine inflammation and stiffness). The injection targets specific nerves to reduce pain while your current disease treatment continues.
Istanbul, PendikAges 18–65 - NCT07637084Recruiting
Light therapy for chronic pain and fatigue in Ehlers-Danlos Syndrome
This trial tests whether a non-invasive light therapy called photobiomodulation can reduce chronic pain and fatigue in people with hypermobile Ehlers-Danlos Syndrome (hEDS), a genetic condition affecting connective tissue. The light is applied to the skin and may help cells produce energy and reduce inflammation.
Boulogne-Billancourt, Île-de-France RegionAges 18 years+ - NCT07637227Recruiting
Comparing two types of clear aligners for teeth straightening
This study tests two different ways of making clear aligners (custom plastic trays that move your teeth). Researchers want to see if 3D-printed aligners work as well as traditional heat-formed ones for mild crowding or spacing.
Baghdad, Bab Al-MuadhamAges 15–30 - NCT07638137Recruiting
Advanced Heart Catheter Testing for Stent Patients With Chest Pain
This study tests a detailed diagnostic procedure during heart catheterization for patients who previously had stents placed and now have chest pain or signs of heart stress. The goal is to better understand blood flow in treated arteries to guide treatment decisions.
Leganés, MadridAges 18 years+ - NCT07639944Recruiting
REN Device Study for Jaw Pain and Headaches
This study tests whether a treatment called REN can help reduce headaches and jaw pain caused by temporomandibular disorders (TMD). You would use the REN device at home on your smartphone or tablet over several months.
Ridgeland, MississippiAges 12 years+ - NCT07640282Recruiting
Nerve Blocks for Pain After Kidney Removal Surgery
This trial compares two types of nerve-blocking injections (ESP and EXORA blocks) to reduce pain after laparoscopic kidney removal surgery. The goal is to see which method works better for controlling pain after the procedure.
Istanbul, IstanbulAges 18–80 - NCT07640646Recruiting
Heart Surgery and Long-Term Pain: A Patient Survey
This study asks patients who had heart surgery in the past year about any ongoing pain or discomfort in the surgical area. The goal is to understand how common long-term pain is after heart surgery and how it affects daily life.
Leuven, Vlaams BrabantAges 18 years+ - NCT07642674Recruiting
IV Pain Relief After Shoulder Arthroscopy Surgery
This study tests whether an intravenous pain medication (dexketoprofen) given during shoulder arthroscopy can reduce pain that returns after surgery ends. Researchers want to see if this approach helps keep patients more comfortable and need fewer pain medications overall.
Eskişehir, OdunpazarıAges 18–70 - NCT07642882Recruiting
Brain Stimulation for Fibromyalgia Pain Relief
This study tests whether a non-invasive brain stimulation treatment (rTMS) can reduce chronic pain in fibromyalgia patients. The treatment uses magnetic pulses to stimulate specific areas of the brain and may help relieve widespread pain.
Boulogne-Billancourt, Île-de-France RegionAges 18–80 - NCT07645014Recruiting
Physical Therapy for PCOS Pain and Irregular Periods
This study compares two hands-on physical therapy techniques to see if they help reduce period pain and improve symptoms in women with PCOS (a hormone condition affecting the ovaries). You'll receive either neurodynamic stretching or myofascial release therapy to see which works better.
Lahore, Punjab ProvinceAges 18–35 - NCT07645989Recruiting
Registry tracking long-term outcomes after MuseCell treatment
This registry follows patients who have received Dezawa MuseCells (a type of cell therapy) to understand how well the treatment works over 5 years. You'll complete online surveys about your health and progress periodically.
North Palm Beach, FloridaAges Up to 89 years - NCT07649876Recruiting
Virtual Reality to Reduce Anxiety in Critically Ill Patients
This study tests whether wearing a virtual reality headset—which shows calming scenes like nature—can help reduce anxiety, agitation, and confusion in patients admitted to the intensive care unit. The goal is to see if VR can help patients feel more comfortable during their recovery.
Hershey, PennsylvaniaAges Any age - NCT07650422Recruiting
Virtual Reality to Reduce Anxiety During Cervical Screening
This study tests whether wearing a virtual reality headset during a colposcopy (a procedure to examine the cervix) can help reduce anxiety, stress, and pain. You would be randomly assigned to either use VR or receive standard care during the procedure.
Adana, AdanaAges 18 years+ - NCT07650760RecruitingPhase 4
Pain Relief After Gallbladder Removal Surgery
This trial tests whether flushing the abdomen with a numbing medication (bupivacaine) during minimally invasive gallbladder surgery reduces pain after the procedure compared to using saline (salt water) alone.
Wāh, Punjab ProvinceAges 18–60 - NCT07650877Recruiting
Pain relief blocks for minimally invasive chest surgery
This study compares two different types of nerve blocks (numbing injections near the ribs) to see which one works better for pain relief after minimally invasive chest surgery. Both techniques are standard care options, and the trial will help doctors understand which one provides the best pain control.
Çankaya, AnkaraAges 18–75 - NCT07651722Recruiting
Pain control and gut recovery after abdominal surgery
This trial tests a combination of two pain-management approaches—a long-acting numbing medicine injected near nerves and a self-administered opioid—to see if they help your gut function better and control pain after bowel or colon surgery.
Tianjin, Tianjin MunicipalityAges 18–80 - NCT07652944Recruiting
Magnetic field therapy for chronic lower back pain
This trial tests whether magnetic fields applied to your back can relieve chronic lower back pain that has lasted at least 12 weeks. It's for people aged 18 to 64 who are willing to attend all study visits.
Edwards Air Force Base, CaliforniaAges 18–64
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,764 recruiting pain medicine studies from the U.S. registry right now, out of 6,842 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.