Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,575 recruiting studies in this area right now.
By phase
- Not applicable2,950
- Phase 4240
- Phase 2131
- Phase 3102
- Phase 193
- Phase 2/Phase 337
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University84
- Cairo University59
- Beijing Tiantan Hospital34
- Tanta University33
- Ain Shams University28
- Foundation University Islamabad28
- Mayo Clinic25
- VA Office of Research and Development23
- Hacettepe University22
- Stanford University20
Where studies are running
- California151
- New York79
- Massachusetts65
- Florida64
- Texas51
- Illinois40
- North Carolina40
- Maryland39
- Ohio39
- Minnesota37
Recruiting studies3,575 total
- NCT07747649Recruiting
Multisensory stimulation for pain from newborn heel pricks
This study tests whether combining gentle touches, sounds, and other sensory input can reduce pain when newborns get a routine heel prick for blood tests. If you have a healthy newborn staying with you in the hospital's newborn care unit, this might make those pricks less uncomfortable.
Ankara, BeşevlerAges 1 day–4 weeks - NCT07743710Recruiting
Telehealth smoking study for chronic pain
This study tests a telehealth program to help people with chronic pain learn about smoking and pain management. It may help you understand how smoking affects your pain and explore ways to reduce smoking without quitting right away.
Binghamton, New YorkAges 18 years+ - NCT07745972Recruiting
Pain relief block for gallbladder surgery
This trial tests a numbing injection near the ribs to reduce pain after laparoscopic gallbladder removal. It may help you recover with less discomfort.
IstanbulAges 18–80 - NCT07746973Enrolling by invitation
Magic show to reduce pain and fear during needle procedures
This study tests whether watching a magic show called 'Kuco' during a needle procedure (like getting blood drawn or an IV) helps children aged 5 to 8 feel less pain and fear. If your child needs a needle and can watch the show, they might be eligible to join.
Bingoel, BingölAges 5–8 - NCT07741227Recruiting
Electric acupuncture for chronic neck pain
This study tests whether electric acupuncture can reduce stiffness and pain in the neck muscles. It may be a treatment option if you have had neck pain for at least 3 months and would like to try a non-drug approach.
Hong KongAges 18–65 - NCT07743073Recruiting
Ceylon cinnamon for diabetic nerve pain
This study tests whether taking Ceylon cinnamon daily can help lower blood sugar, improve cholesterol, and reduce nerve pain in adults with type 2 diabetes and painful diabetic peripheral neuropathy. If you qualify, you might get a natural supplement that could ease your symptoms.
AmmanAges 18 years+ - NCT07742826Recruiting
Platelet-rich fibrin vs. steroids after wisdom tooth removal
This study compares two treatments to reduce pain and swelling after removing an impacted wisdom tooth: one uses a special blood clot (platelet-rich fibrin) placed in the socket, and the other uses steroid medication. The goal is to find which works better for healing and comfort.
NicosiaAges 18 years+ - NCT07747623Recruiting
Pain relief options for breast surgery
This study compares two ways of giving pain relief during breast surgery. It aims to find which method controls pain better after the operation.
Yenimahalle, AnkaraAges 18–80 - NCT06613178RecruitingPhase 4
IV acetaminophen for heart surgery recovery
This trial tests if giving acetaminophen (Tylenol) through a vein after heart surgery can help patients recover better. You may be a good fit if you are having planned heart surgery that is not an emergency.
Vancouver, British ColumbiaAges 18 years+ - NCT05919745RecruitingPhase 4
Ibuprofen before mouth surgery to reduce pain sensing
This trial studies whether taking ibuprofen before tooth extraction and bone graft surgery can lower how much pain you feel afterward. It may help by changing the body’s pain response during healing.
Milwaukee, WisconsinAges 18 years+ - NCT06602349Recruiting
Lidocaine injection for chronic anal/perineal pain
This trial tests whether injecting a numbing medicine (lidocaine) into the painful area helps people with chronic, unexplained pain in the anal or perineal region. It is for patients who have not gotten relief from standard treatments and whose MRI shows no other cause.
Paris, Île-de-France RegionAges 18 years+ - NCT07739277Recruiting
Comparing two ways to give a chest wall pain block for breast surgery
This study compares two ways of giving a numbing injection (a nerve block) to the side of the chest wall for pain relief after breast surgery. The goal is to see which method works better for reducing pain and the need for pain medicine.
Ankara, Yenimahalle\AnkaraAges 18–65 - NCT07738770Recruiting
Comparing two numbing techniques for pain relief after mastectomy
This trial tests two different numbing injections to see which one works better for pain after breast cancer surgery. If you are having a mastectomy, you may be able to join and help find a better way to manage pain.
Jakarta, DKI JakartaAges 18–60 - NCT07736144Recruiting
Herbal formula study for fibromyalgia pain relief
This study tests a Chinese herbal formula called Yangyin Roujin (which nourishes yin and softens the muscles) to see if it helps reduce pain and other symptoms of fibromyalgia. If you have fibromyalgia and a pain level of 4 or more, you may be able to join.
Beijing, Beijing MunicipalityAges 18–75 - NCT07740382Recruiting
Pain block comparison for recovery after liver surgery
This study compares two types of pain-relieving nerve blocks used during liver surgery to see which one helps you breathe better and recover more comfortably after the operation.
Alexandria, Sbein-ElkomAges 18–75 - NCT07733583Recruiting
Pelvic floor therapy and exercise for endometriosis pain
This study tests whether a special type of physical therapy (pelvic floor therapy) combined with exercise can help reduce chronic pelvic pain in women with endometriosis. It aims to see if these treatments improve pain, daily function, and quality of life.
Porto Alegre, Rio Grande do SulAges 18–45 - NCT07733752Recruiting
AI symptom-checking for spine pain in physical therapy
This trial tests if a computer tool that checks your symptoms before a visit can help you and your physical therapist make better decisions about your spine care. It is for adults with neck, mid-back, or low back pain (with or without leg pain) who are starting physical therapy.
AsyutAges 18 years+ - NCT07732556Recruiting
Nerve block comparison for shingles pain relief
This trial compares two different nerve blocks (MTP and ESP) to see which works better for treating shingles pain in the chest or back. It could help you if you have moderate to severe shingles pain that started within the last 30 days.
Tanta, El-GharbiaAges 21–60 - NCT07733128Recruiting
Pain relief with buprenorphine patch after lung surgery
This study tests a skin patch that releases buprenorphine, a pain medicine, to control pain after lung surgery. It may help reduce pain and the need for other pain medicines.
Santiago, Santiago MetropolitanAges 18 years+ - NCT07732764Recruiting
TENS for Pain After Chest Surgery
This trial tests if a mild electrical therapy (TENS) can reduce pain after chest surgery. It may help you need less pain medicine and feel better during recovery.
Kaohsiung City, Kaohsiung CityAges 15–85 - NCT07724691Recruiting
Comparing two shoulder therapies for frozen shoulder
This study compares two types of gentle shoulder movements (mobilizations) to treat frozen shoulder. The goal is to reduce pain and help you move your arm more easily.
Lahore, Punjab ProvinceAges 30–50 - NCT07729488Recruiting
Nerve blocks for better recovery after lung surgery
This study compares two types of nerve blocks to see which one helps people recover better after lung surgery. It tests a block around the spine versus one near the shoulder blade to improve comfort and recovery.
Diyarbakır, Outside of the USAges 18–85 - NCT07727551Recruiting
Nerve block before knee replacement for better recovery
This trial tests if a nerve block given a few weeks before knee replacement surgery can improve pain and function after the operation. It is designed for people who have certain risk factors that might make recovery harder.
BrusselsAges 18–60 - NCT07724470Recruiting
Stretching techniques for neck and arm pain
This study tests two types of stretching to see which one works better for neck pain that spreads into the arm. If you have had this pain for more than a month, this trial might help find a way to move better and feel less pain.
Lahore, Punjab ProvinceAges 30–60
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,575 recruiting pain medicine studies from the U.S. registry right now, out of 6,452 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.