Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,576 recruiting studies in this area right now.
By phase
- Not applicable2,951
- Phase 4240
- Phase 2131
- Phase 3102
- Phase 193
- Phase 2/Phase 337
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University84
- Cairo University60
- Beijing Tiantan Hospital34
- Tanta University33
- Ain Shams University28
- Foundation University Islamabad28
- Mayo Clinic25
- VA Office of Research and Development23
- Hacettepe University22
- Stanford University21
Where studies are running
- California152
- New York79
- Massachusetts65
- Florida64
- Texas50
- North Carolina41
- Illinois40
- Maryland39
- Ohio39
- Minnesota37
Recruiting studies3,576 total
- NCT06639009Recruiting
Laser treatment for better mouth opening in oral fibrosis
This study tests if a special laser therapy (photobiomodulation) helps people with oral submucous fibrosis open their mouths wider. It's for people who haven't had other treatments for this condition in the last three months.
New Delhi, National Capital Territory of DelhiAges 18–99 - NCT06641206Recruiting
Dexmedetomidine injection for chronic knee pain
This trial tests whether a single injection of dexmedetomidine into the knee joint can reduce chronic knee pain. It is for people who are not scheduled for knee surgery and have no serious health problems.
Tanta, El GharbyiaAges 40–75 - NCT06644807Recruiting
Neuromodulation for phantom limb pain after amputation
This trial tests a new approach to suppress phantom limb pain using neuromodulation methods. It may help people who have had a limb amputated and continue to experience persistent pain.
Moscow, MoscowAges 18–65 - NCT05970783RecruitingPhase 3
Jincaopian tablets for ongoing pelvic pain after pelvic infection
This trial tests whether Jincaopian tablets can reduce long-lasting pelvic pain that happened after pelvic inflammatory disease. You may be able to join if your pain is still moderate to severe and other causes of pelvic pain have been ruled out.
Beijing, Beijing MunicipalityAges 18–50 - NCT07701772Recruiting
Laser vs phenol for pilonidal sinus: which works better?
This trial compares laser treatment to crystallized phenol for a common skin condition called pilonidal sinus. Both are minimally invasive options that may help avoid surgery.
Sanliurfa, ŞanlıurfaAges 18 years+ - NCT07704931Enrolling by invitation
Can spinal cord stimulation repair small nerve fibers?
This study tests whether a special type of spinal cord stimulation (which uses mild electrical pulses to block pain) can help repair damaged small nerve fibers in people with small fiber neuropathy. If you have chronic nerve pain and meet the criteria, you may be able to join.
Grand Island, NebraskaAges 19 years+ - NCT07699601RecruitingPhase 2/Phase 3
Testing a pain tablet after orthopedic surgery
This trial tests an investigational tablet called HL-1186 for controlling pain after orthopedic surgery. It explores whether the drug can safely reduce moderate to severe pain when given after the procedure.
Changsha, HunanAges 18–75 - NCT07703917Recruiting
TENS for Uterine Pain During Breastfeeding
This study tests if a gentle electrical device (TENS) can help reduce uterine pain women sometimes feel during breastfeeding after giving birth. The results could offer a drug-free way to manage this discomfort.
NazarethAges 18 years+ - NCT07698665Recruiting
Ketamine vs dexmedetomidine in scalp block for brain tumor surgery
This trial compares two medicines, ketamine and dexmedetomidine, added to a scalp nerve block during brain tumor removal surgery. The goal is to see which provides better pain control and recovery after surgery.
Cairo, GovernorateAges 20–60 - NCT07700108RecruitingPhase 2
Pain relief for epidural needle insertion in pregnant women
This study compares two ways to numb the skin before placing an epidural needle: a lidocaine patch placed on the back versus a lidocaine injection under the skin. The goal is to find which method is more comfortable for pregnant women during labor or cesarean delivery.
Columbus, OhioAges 18 years+ - NCT07699744RecruitingPhase 4
Steroid injection study for pain after shoulder surgery
This trial tests if adding a steroid (dexamethasone) to a nerve block shot can reduce the severe pain that often returns after shoulder surgery. You will receive either a single injection or a continuous flow of pain medicine through a small tube.
Seoul, Jongno-guAges 19–79 - NCT07699224Recruiting
Menstrual cycle symptoms and women's health study
This study looks at the natural menstrual cycle symptoms and overall health in women who are not using hormonal birth control. It aims to understand how cycle-related symptoms affect daily life.
MadridAges 18–45 - NCT07703332Recruiting
Stretching methods for arm pain from overuse
This study tests two different stretching techniques to see which one better relieves arm pain and improves movement in people with overuse injuries. It may help you if you have long-lasting discomfort from repetitive activities like typing or manual work.
Faisalabad, Punjab ProvinceAges 20–50 - NCT07699575Recruiting
Can turmeric and ginger help runner recovery?
This trial tests whether taking turmeric, ginger, and black pepper supplements can reduce inflammation and aid recovery in runners completing the 175 km 'Diagonale des Fous' race. It could help you understand natural ways to manage post-race inflammation.
Saint-Pierre, CHU de La RéunionAges 18 years+ - NCT07705698Recruiting
Nordic exercise for young female pole vaulters
This study compares two types of Nordic hamstring exercises—one with blood flow restriction and one without—to see which better helps elite young female pole vaulters strengthen their hamstrings and reduce injury risk.
AdanaAges 12–18 - NCT07704554Recruiting
Dural puncture epidural for labor pain relief
This study compares a modified epidural technique (dural puncture epidural) to the standard method for managing labor pain. It aims to see if the new approach is safer or works better for women in labor.
Columbus, OhioAges 18 years+ - NCT07704970Recruiting
Nerve block for pain relief in robotic kidney surgery
This trial tests a special nerve block called QLESP to control pain after robotic partial kidney removal. It may reduce the need for strong pain medicines and improve recovery.
Wuhan, HubeiAges 18–80 - NCT07706244Recruiting
Does reducing pre-surgery anxiety help orthopedic patients recover better?
This study tests if a program to reduce anxiety before surgery (Enhanced Recovery After Surgery) improves how patients feel one year after major orthopedic surgery like knee, hip, or spine procedures, compared to standard care.
Hualien City, Hualien CountyAges 20–100 - NCT07705490Recruiting
Magnetic stimulation for traumatic nerve injury pain
This trial tests whether high-intensity magnetic pulses applied to the injured area can reduce pain and improve muscle strength after a traumatic peripheral nerve injury. It is for people who still have pain and weakness at least 3 months after the injury.
AnkaraAges 18–65 - NCT06415032Recruiting
Quilting sutures after mastectomy to improve recovery
This study tests whether using special stitches (quilting sutures) during mastectomy helps reduce fluid buildup or other complications after surgery. It is for people having one breast removed without immediate reconstruction.
LeuvenAges 18 years+ - NCT06650046Recruiting
Topping-off technique for lower back arthritis
This trial tests a 'topping-off' surgical technique for people with arthritis and disc problems in the lower back. If you have tried 3 months of non-surgical treatments without success, this surgery may be an option to relieve pain and improve function.
Jinan, ShandongAges 18–85 - NCT07697560RecruitingPhase 1
Safety of AH-008 in healthy volunteers
This trial tests a new medicine called AH-008 in healthy people to see if it's safe and how the body processes it. It is a first-in-human study with a single dose.
Salt Lake City, UtahAges 18–65 - NCT05382845Recruiting
Screening for pelvic pain in early pregnancy
This study looks to identify pregnancy-related pelvic girdle pain in pregnant people early in pregnancy (before 20 weeks). It may help doctors spot who is likely to develop pelvic pain and guide earlier support.
Karlskrona, Blekinge CountyAges Any age - NCT06652581Recruiting
Testing a nerve block for gallbladder surgery pain
This study tests a special nerve block called M-TAPA to see if it helps control pain during and after gallbladder removal surgery. It might offer better pain relief with fewer side effects.
Denpasar, BaliAges 18–65
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,576 recruiting pain medicine studies from the U.S. registry right now, out of 6,474 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.