Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,749 recruiting studies in this area right now.
By phase
- Not applicable3,095
- Phase 4251
- Phase 2145
- Phase 3104
- Phase 197
- Phase 2/Phase 335
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University96
- Cairo University62
- Beijing Tiantan Hospital34
- Ain Shams University31
- Mayo Clinic28
- Tanta University28
- Foundation University Islamabad26
- Stanford University24
- VA Office of Research and Development22
- Hacettepe University20
Where studies are running
- California160
- New York81
- Massachusetts68
- Florida63
- Texas51
- Ohio47
- Maryland42
- Minnesota42
- North Carolina38
- Illinois37
Recruiting studies3,748 total
- NCT06806514Recruiting
Exercise and muscle strength in chronic low back pain
This trial measures how well you can use your arms and how strong your breathing and other muscles are if you have chronic low back pain. It aims to understand the links between these factors to improve future treatments.
KırşehirAges 18–65 - NCT06808022Enrolling by invitation
Back exercises before spine surgery
This trial studies whether doing back exercises before spine surgery helps improve recovery. If you are having spine surgery and can safely do physical therapy, you may be able to join.
La Jolla, CaliforniaAges 18 years+ - NCT07004686Recruiting
Guided anesthesia to reduce opioid use in gallbladder surgery
This study tests a new way of guiding anesthesia during gallbladder removal surgery, with the goal of using less opioid pain medicine. It may help you have a smoother recovery with fewer side effects.
Shenzhen, GuangdongAges 18–64 - NCT07605013Recruiting
Neck Exercises for Office Workers: Building Strength and Function
This study tests whether specific neck mobilization techniques (gentle movements and stretches) can improve neck strength and function in desk workers. You would be a healthy control participant to help researchers understand how these techniques work in people without existing neck pain.
IstanbulAges 18–40 - NCT06752759RecruitingPhase 3
Ketamine mist for depression
This trial tests if a ketamine mist you breathe in can help treat moderate to severe depression. It is for adults who are not helped enough by other treatments.
Brooklyn, New YorkAges 18–88 - NCT03751566Recruiting
Acupuncture to ease short-term side effects of head and neck radiation
This trial studies whether adding acupuncture to standard radiation care can reduce short-term side effects from radiation for head and neck tumors. You might qualify if you are having treatment with the goal of cure or after-surgery prevention and can reliably complete symptom/side-effect tracking.
BrnoAges 18 years+ - NCT07286630Enrolling by invitation
Disability and fear avoidance in physical therapists
This study looks at how common disability and fear-related beliefs are among Egyptian physical therapists who have long-term low back pain. If you qualify, you will answer questionnaires about your pain, your thoughts about movement, and how it affects your daily life.
CairoAges 25–55 - NCT07628413Recruiting
Exercise Methods for Neck and Shoulder Pain
This study compares two types of gentle exercise programs—Egoscue and Feldenkrais—to help people with chronic neck pain and poor posture. Both programs focus on retraining muscles and improving how your body moves, and the study will measure which approach works better.
Lahore, Punjab ProvinceAges 25–45 - NCT07626489Recruiting
Numbing injection to reduce pain after lung surgery
This trial tests whether injecting a numbing medication (ropivacaine) mixed with a steroid (Diprospan) into the surgical area before chest surgery can reduce pain after the procedure. If it works, patients may need fewer pain pills and feel more comfortable during recovery.
Beijing, Beijing MunicipalityAges 18–64 - NCT05432895Recruiting
Compare moving vs fixed night splints for heel pain
This study compares two types of night splints to treat early plantar fasciitis (heel pain). It aims to see which splint type helps your symptoms and walking more after nighttime use.
Palo Alto, CaliforniaAges 18–99 - NCT03415828Recruiting
Testing ethanol gel versus steroid gel for low back disc pain
This study compares two gels put on or into the painful disc area: an ethanol gel versus a steroid gel. It is for adults with long-lasting low back disc pain that did not improve with usual non-surgical care.
BordeauxAges 18 years+ - NCT07079865Recruiting
Nerve stimulation for pain after spine fracture
This trial tests a 60-day nerve stimulation treatment to reduce pain and improve mobility after a recent spine fracture caused by osteoporosis. It may help patients who still have significant pain despite over-the-counter pain relievers.
Avenel, New JerseyAges 18 years+ - NCT07064200Recruiting
Timing of TAP blocks for abdominal surgery
This study compares two different ways to give a numbing medicine (TAP block) before abdominal surgery to see which one works better for pain control. If you are scheduled for elective abdominal surgery, joining may help doctors find the best way to manage your pain.
New York, New YorkAges 18–65 - NCT07486830RecruitingPhase 2
Botox for Painful Vestibulodynia with Tight Pelvic Floor Muscles
This trial tests whether Botox (incobotulinumtoxinA) can help reduce pain in women with provoked vestibulodynia (pain at the vaginal opening) and overactive pelvic floor muscles. If you qualify, you will receive an injection and be monitored for improvement.
Washington D.C., District of ColumbiaAges 18 years+ - NCT07487987Recruiting
Imagery and exercises for chronic neck pain
This trial tests whether imagining movements (motor imagery) and doing special neck exercises can help people with long-term neck pain. You may be eligible if your neck pain has lasted at least 3 months and is at least moderate, and you haven't had recent neck surgery or therapy.
Konya, KaratayAges 18–65 - NCT03404778Enrolling by invitation
Collecting data on reverse shoulder implants for weak rotator cuff
This study collects real-world information about a reverse shoulder implant used when the rotator cuff is badly damaged. It may help improve how these implants are chosen and how well they work for pain relief and improving arm function.
Towson, MarylandAges 18 years+ - NCT07602387Recruiting
Capsaicin cream for chemo-related nerve pain in legs
This study tests whether an 8% capsaicin cream (a chili-pepper derived treatment) can help reduce nerve pain and numbness in the legs caused by cancer chemotherapy drugs (taxanes). The cream is applied directly to affected areas, and the research team will track whether it improves your symptoms and pain levels over time.
Boulogne-Billancourt, HAUTS DE SEINEAges 18 years+ - NCT07646184Enrolling by invitation
Nerve Block Techniques for Upper Back Surgery Pain
This trial compares two types of numbing injections (nerve blocks) used during upper back spine surgery to see which one works better for pain relief. Both techniques are already used in surgery; this study tests which may be more effective.
Tanta, State/Province:*Ages 18–60 - NCT07496983Recruiting
Using platelet-rich plasma (PRP) for tennis elbow
This study tests a treatment for tennis elbow called platelet-rich plasma (PRP), which uses your own blood to help the tendon heal. It looks at who benefits most from a PRP injection given within the last 48 hours.
PloemeurAges 18 years+ - NCT07607249Enrolling by invitation
Floating Needle Treatment for Stomach Issues After Knee Surgery
This trial tests whether a traditional Chinese acupuncture technique called 'floating needle' can help with stomach and bowel problems that sometimes happen after knee surgery under general anesthesia. You would receive this treatment along with standard post-surgery care to see if it reduces nausea, constipation, or other digestive issues.
Guangzhou, GuangdongAges 18 years+ - NCT06778070Recruiting
Pelvic pain study testing yoga therapy for relief
This trial tests whether yoga therapy can help reduce chronic pelvic pain in women and non-binary individuals over 6 months. You'll join online yoga classes and see if they improve your pain and daily life.
San Francisco, CaliforniaAges 18 years+ - NCT07095725Recruiting
Effect of Period Pain on Muscle Activity in Young Women
This trial studies how primary dysmenorrhea (period pain) affects muscle activity in young women aged 18-25. It may help understand why period pain happens and guide future treatments.
GizaAges 18–25 - NCT07717918RecruitingPhase 1
Testing a new eye drop for capsaicin-induced eye pain
This trial tests whether a new eye drop, BL1332, can reduce eye pain caused by capsaicin (the compound that makes chili peppers spicy). If you are a healthy adult and have no eye problems, this study could help see if the drop is safe and works.
Newport Beach, CaliforniaAges 18–65 - NCT07510373Recruiting
Helping patients cut back on opioids after orthopedic surgery
This trial tests a program to help patients safely reduce their opioid pain relievers after leaving the hospital following orthopedic surgery. It is designed for people who are new to opioids and want to avoid long-term use.
The Bronx, New YorkAges 18 years+
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,749 recruiting pain medicine studies from the U.S. registry right now, out of 6,757 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.