Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,576 recruiting studies in this area right now.
By phase
- Not applicable2,951
- Phase 4240
- Phase 2131
- Phase 3102
- Phase 193
- Phase 2/Phase 337
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University84
- Cairo University60
- Beijing Tiantan Hospital34
- Tanta University33
- Ain Shams University28
- Foundation University Islamabad28
- Mayo Clinic25
- VA Office of Research and Development23
- Hacettepe University22
- Stanford University21
Where studies are running
- California152
- New York79
- Massachusetts65
- Florida64
- Texas50
- North Carolina41
- Illinois40
- Maryland39
- Ohio39
- Minnesota37
Recruiting studies3,576 total
- NCT06290011Recruiting
Mixed reality for chronic pain relief
This study tests a new therapy that uses mixed reality (a type of glasses that shows virtual images over the real world) to help distract you from pain and teach relaxation. It may help people with chronic pain who have not tried VR or MR before.
Shanghai, YangpuAges 18–85 - NCT06684249Recruiting
Comparing nerve block and Botox for chronic migraine
This study compares two treatments for chronic migraine: a nerve block (injection near the nerves in the head) and Botox injections. It aims to see which one works better to reduce headache days and improve quality of life.
Zagazig, Sharqia ProvinceAges 18–65 - NCT06015165Recruiting
Pain control plan for complex anorectal surgery
This study tests a pain management plan led by anesthesiologists for people having complex anorectal surgery. The goal is to see if this approach can better control pain and improve recovery.
Beijing, Beijing MunicipalityAges 18–85 - NCT07651722Recruiting
Pain control and gut recovery after abdominal surgery
This trial tests a combination of two pain-management approaches—a long-acting numbing medicine injected near nerves and a self-administered opioid—to see if they help your gut function better and control pain after bowel or colon surgery.
Tianjin, Tianjin MunicipalityAges 18–80 - NCT07650396RecruitingPhase 3
Steroid Injections for Long-Term Achilles Tendon Pain
This study tests whether steroid injections can help people with chronic Achilles tendon pain (the tendon at the back of your heel) who haven't improved with physical therapy and exercise. The injection is designed to reduce inflammation and pain in the middle part of the tendon.
RotterdamAges 18–65 - NCT07649876Recruiting
Virtual Reality to Reduce Anxiety in Critically Ill Patients
This study tests whether wearing a virtual reality headset—which shows calming scenes like nature—can help reduce anxiety, agitation, and confusion in patients admitted to the intensive care unit. The goal is to see if VR can help patients feel more comfortable during their recovery.
Hershey, PennsylvaniaAges Any age - NCT07650877Recruiting
Pain relief blocks for minimally invasive chest surgery
This study compares two different types of nerve blocks (numbing injections near the ribs) to see which one works better for pain relief after minimally invasive chest surgery. Both techniques are standard care options, and the trial will help doctors understand which one provides the best pain control.
Çankaya, AnkaraAges 18–75 - NCT07650526Recruiting
Brain Stimulation for Nerve Pain Relief
This study tests two types of magnetic brain stimulation (aiTBS and rTMS) to treat long-lasting nerve pain. Researchers want to see which approach works better and develop a way to predict who will benefit most.
Boulogne-Billancourt, Île-de-France RegionAges 18–80 - NCT07647276Recruiting
Massage and relaxation for period pain relief
This study tests whether connective tissue massage (a hands-on technique) and progressive relaxation exercises can reduce severe menstrual cramps. If you have primary dysmenorrhea—painful periods without an underlying medical cause—this trial may help you find natural pain relief.
DenizliAges 18–30 - NCT07650422Recruiting
Virtual Reality to Reduce Anxiety During Cervical Screening
This study tests whether wearing a virtual reality headset during a colposcopy (a procedure to examine the cervix) can help reduce anxiety, stress, and pain. You would be randomly assigned to either use VR or receive standard care during the procedure.
Adana, AdanaAges 18 years+ - NCT07648342Recruiting
Eye Pupil Response to Predict Pain After Heart Surgery
This study looks at how your eye pupils respond to light as a way to predict how much pain you might feel when sedation (sleep medicine) is stopped after heart surgery. The goal is to help doctors better manage your pain during recovery.
DijonAges 18 years+ - NCT07653906Recruiting
Nerve block for upper abdominal cancer pain
This trial compares two nerve-block procedures to see which better relieves severe pain from cancers in the upper belly (like pancreas, stomach, liver, or bile duct). It may help if you have moderate to severe pain and are not pregnant or have certain medical conditions.
DhakaAges 18 years+ - NCT07652086Recruiting
Body Awareness Therapy for Young, Healthy Adults
This study tests Basic Body Awareness Therapy, a gentle movement program designed to improve how you understand and control your body. Researchers want to see how it affects balance, posture, and overall movement quality in healthy young adults.
AnkaraAges 18–40 - NCT07646899Recruiting
Unstable Loads and Shoulder Movement in Overhead Athletes
This study investigates how using unstable equipment (like a wobbly barbell) affects shoulder blade movement and muscle use during overhead pressing in athletes with shoulder impingement pain. The goal is to understand whether unstable loads might help improve shoulder mechanics and reduce pain in overhead athletes.
TaipeiAges 18–40 - NCT07647367Recruiting
Nerve blocks to reduce pain after breast cancer surgery
This trial compares two types of nerve-blocking injections given before breast removal surgery to help reduce pain and improve recovery. The goal is to see which method works better for comfort and quality of life after surgery.
Tanta, Gharbia GovernorateAges 18–65 - NCT07654192Enrolling by invitation
ShotBlocker and finger puppet for blood draw pain
This study tests two simple distraction methods—a small plastic device called ShotBlocker and a finger puppet—to see if they help reduce pain and fear during blood draws in children. It may help your child feel more comfortable and less scared.
BoluAges 5–10 - NCT07650591Recruiting
Tapping and vibration to ease needle pain in children
This study tests whether rhythmic tapping and gentle vibration near the skin can help children ages 6–12 feel less pain and fear during blood draws. Researchers want to see if these simple techniques can make the procedure more comfortable.
Antalya, KepezAges 6–12 - NCT07648784Recruiting
Pain Relief Comparison for Lower Leg Surgery
This trial tests different combinations of two numbing medicines (lidocaine and bupivacaine) given through the spine to manage pain during lower limb surgery. The goal is to find which mixture works best and lasts longest.
Karachi, SindhAges 20–60 - NCT07650760RecruitingPhase 4
Pain Relief After Gallbladder Removal Surgery
This trial tests whether flushing the abdomen with a numbing medication (bupivacaine) during minimally invasive gallbladder surgery reduces pain after the procedure compared to using saline (salt water) alone.
Wāh, Punjab ProvinceAges 18–60 - NCT06290024Recruiting
Nerve pain study: tracking long-term symptoms
This study follows people with nerve pain over time to learn more about their condition. You will not receive a new treatment, but your data will help doctors understand neuropathic pain better.
Shanghai, YangpuAges 18–85 - NCT06674772Recruiting
Migraine study measuring CGRP levels by age and sex
This study measures a substance called CGRP in saliva from people with migraine and healthy volunteers to see how it changes with age and sex. It may help researchers understand migraine better.
Barcelona, BarcelonaAges 6–75 - NCT06686706Recruiting
Treating Plantar Fasciitis with Special Taping and Massage
This study tests two treatments for heel pain caused by plantar fasciitis: a special scraping technique (IASTM) and kinesio taping. It may help if you stand for long hours and have morning heel pain that gets better then worse with activity.
Rawalpindi, Punjab ProvinceAges 20–40 - NCT06686290Recruiting
Stretching exercises for levator scapulae pain
This trial compares two stretching techniques to relieve chronic neck and shoulder blade pain caused by tight levator scapulae muscles. It may help you if you have had this pain for at least 3 months and have trouble turning or tilting your head.
Daska Kalan, Punjab ProvinceAges 24–59 - NCT06687018Recruiting
Comparing two hand therapies for carpal tunnel relief
This study tests two types of gentle hand and wrist movements (mobilizations) to see which better relieves pain, tingling, and numbness in carpal tunnel syndrome. It may help you if you have these symptoms and are otherwise healthy.
Lahore, Punjab ProvinceAges 20–45
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,576 recruiting pain medicine studies from the U.S. registry right now, out of 6,474 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.