Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,576 recruiting studies in this area right now.
By phase
- Not applicable2,951
- Phase 4240
- Phase 2131
- Phase 3102
- Phase 193
- Phase 2/Phase 337
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University84
- Cairo University60
- Beijing Tiantan Hospital34
- Tanta University33
- Ain Shams University28
- Foundation University Islamabad28
- Mayo Clinic25
- VA Office of Research and Development23
- Hacettepe University22
- Stanford University21
Where studies are running
- California152
- New York79
- Massachusetts65
- Florida64
- Texas50
- North Carolina41
- Illinois40
- Maryland39
- Ohio39
- Minnesota37
Recruiting studies3,576 total
- NCT07659990Recruiting
Comparing two nerve blocks for mastectomy pain relief
This study compares two types of nerve blocks given before a mastectomy (breast removal surgery) to see which one provides better pain relief. If you are having a mastectomy on one side with lymph node removal, you may be able to join.
Bursa, NilüferAges 18–75 - NCT07655323Recruiting
RISS vs. ESP Block for Gallbladder Surgery Pain
This study compares two types of nerve blocks (RISS and ESP) to manage pain after gallbladder removal surgery. It aims to find which block provides better pain relief.
Bursa, NilüferAges 18–75 - NCT07655336Recruiting
Nerve block comparisons for lung-sparing chest surgery
This trial compares two types of nerve blocks to manage pain during and after a type of lung surgery that removes only part of the lung. It aims to find which block provides better pain relief and recovery.
Bursa, NilüferAges 18–75 - NCT07655271Recruiting
Pain, arm function, and anxiety after shoulder surgery for brachial plexus palsy
This study examines pain, arm function, and social appearance anxiety in adults who had shoulder tendon transfer surgery as children for brachial plexus birth palsy. It helps understand long-term outcomes after this specific surgery.
Istanbul, IstanbulAges 18–40 - NCT07658521Enrolling by invitation
Nerve blocks for pain after heart bypass surgery
This study tests whether adding two numbing injections (nerve blocks) to standard care provides better pain relief after heart bypass surgery. It is for adults having planned surgery and compares pain scores and recovery.
Cairo, Cairo GovernorateAges 18–75 - NCT07659015Enrolling by invitation
Using a hand exercise tool during IV placement
This study tests if using a simple hand-extension rubber band during IV placement can help reduce pain or improve the procedure. It may be an option for right-handed adults getting an IV in specific arm veins.
Konya, MeramAges 18–65 - NCT07661758RecruitingPhase 3
Lidocaine to prevent headache after C-section
This trial tests if giving lidocaine through an IV can prevent the headache that sometimes happens after spinal anesthesia during a planned C-section. If you are having a planned C-section with spinal anesthesia and meet other health requirements, this study might help reduce your risk of post-procedure headache.
Tanta, Gharbia GovernorateAges 18 years+ - NCT07657845Recruiting
Long-term safety of a freezing nerve block before pectus surgery
This study checks the long-term safety of a procedure called cryoneurolysis, which uses cold to temporarily numb certain nerves before surgery to fix a sunken chest (pectus excavatum). It may be for people who already had this treatment.
Bergamo, BGAges 14 years+ - NCT07662733Recruiting
Acupuncture for better sleep and less pain after lung cancer surgery
This trial tests if acupuncture given before and after surgery can help patients sleep better and have less chronic pain after a lung cancer operation. You may join if you are having a specific type of lung cancer surgery, are in good general health, and do not have severe sleep problems already.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07659145Recruiting
Simulation training for ultrasound-guided nerve block in students
This trial tests if a simulation-based training program helps medical students learn how to perform an ultrasound-guided nerve block (a numbing injection near the sciatic nerve). If you're a medical student, you may join to practice and improve your skills.
Santiago, Santiago MetropolitanAges Any age - NCT07659236Recruiting
Plasma-activated water for fibromyalgia pain
This study tests whether a special water called 'plasma-activated water' can help reduce pain in people with fibromyalgia. If you have widespread pain for at least 3 months and meet the age and health requirements, you may be able to join.
TaipeiAges 20–75 - NCT07657390RecruitingPhase 1/Phase 2
Acupoint plaster for moderate to severe cancer pain
This study tests a special pain-relief plaster placed on acupoints (body points used in acupuncture) to see if it can help people with moderate to severe cancer pain who are already taking pain medications. The goal is to find a gentler way to improve pain control.
BeijingAges 18 years+ - NCT07655921Recruiting
Enhanced recovery after knee replacement surgery
This trial tests a special care plan called ERAS to help people recover faster after total knee replacement. It compares this plan to standard care to see if it reduces hospital stay and improves recovery.
Karachi, SindhAges 50–70 - NCT07657949Recruiting
Nerve block for pain after breast reduction surgery
This trial tests a specific nerve block to see if it can reduce pain after breast reduction surgery, possibly helping with recovery and lowering the need for strong painkillers.
Sivas, SivasAges 18–65 - NCT07655388Recruiting
Wound healing and dressing changes after hip replacement
This study compares different types of dressings and how often they should be changed after total hip replacement surgery. It aims to find the best way to help the surgical wound heal.
Novi SadAges 65–95 - NCT07660523Recruiting
Shockwave therapy for neck and shoulder muscle pain
This trial tests if focused shockwave therapy can help people with long-term neck and shoulder pain caused by tight muscles in the upper back. The goal is to see if this treatment is safe and effective for easing pain and improving daily activities.
Kaohsiung CityAges 20 years+ - NCT07662421Recruiting
Slump lateral bending test for leg pain from nerve issues
This study tests how well a simple physical exam maneuver (the slump lateral bending test) can identify nerve-related leg pain (lumbar radicular pain). If you have symptoms like pain, tingling, or numbness down your leg that might be coming from a nerve, this study could help improve diagnosis.
Parma, PRAges 18–75 - NCT07655804RecruitingPhase 3
Calcitonin injection for shingles pain in older adults
This trial tests whether a medication called calcitonin (given as a shot under the skin) can help reduce pain in people with a recent shingles outbreak. It is for adults 50 and older who have moderate to severe pain from their rash.
Tanta, Gharbia GovernorateAges 50 years+ - NCT06642142Recruiting
When numbness starts after a spine block for breast surgery
This study is testing how quickly numbness starts after a specific type of pain block (erector spinae plane block) given before breast surgery. It may help people who are having breast surgery and are healthy enough to receive this block.
Latina, ItalyAges 18 years+ - NCT06669884Recruiting
New ECG method to quickly sort chest pain in ER
This study tests a new ECG-based technology that may help doctors more quickly sort out the cause of your chest pain in the emergency room. If you have chest pain that needs checking, this tool could help decide how urgent your care is.
Jinan, ShandongAges 18 years+ - NCT06671665Recruiting
Manual therapy for low back pain in women with osteopenia
This study tests if manual therapy (hands-on treatment by a therapist) can reduce low back pain in postmenopausal women who have osteopenia, a condition where bones are weaker than normal but not yet osteoporosis. It aims to help with pain located in the lower back area.
GizaAges 50–60 - NCT07652944Recruiting
Magnetic field therapy for chronic lower back pain
This trial tests whether magnetic fields applied to your back can relieve chronic lower back pain that has lasted at least 12 weeks. It's for people aged 18 to 64 who are willing to attend all study visits.
Edwards Air Force Base, CaliforniaAges 18–64 - NCT07653490Recruiting
Two anesthesia methods for gallbladder surgery
This study tests whether a numbing injection in the back (erector spinae plane block) helps reduce anesthesia needs during gallbladder surgery. It compares two anesthesia methods to see which works better for pain control and recovery.
IstanbulAges 18–65 - NCT07652034Recruiting
Tracking migraine relief after a minimally invasive artery procedure
This study follows adults who undergo a procedure called middle meningeal artery embolization—a minimally invasive treatment that blocks blood flow to a specific artery thought to trigger migraines. The trial simply tracks your symptoms and quality of life before and after the procedure to understand how well it works.
Tacoma, WashingtonAges 18–64
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,576 recruiting pain medicine studies from the U.S. registry right now, out of 6,474 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.