Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,578 recruiting studies in this area right now.
By phase
- Not applicable2,954
- Phase 4240
- Phase 2129
- Phase 3103
- Phase 193
- Phase 2/Phase 337
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University84
- Cairo University59
- Beijing Tiantan Hospital34
- Tanta University33
- Ain Shams University28
- Foundation University Islamabad28
- Mayo Clinic25
- VA Office of Research and Development23
- Hacettepe University22
- Stanford University21
Where studies are running
- California151
- New York79
- Massachusetts65
- Florida64
- Texas50
- North Carolina41
- Illinois40
- Maryland39
- Ohio39
- Minnesota37
Recruiting studies3,578 total
- NCT07352813Recruiting
Comparing numbing methods for kids with MIH teeth
This study tests two ways to numb teeth—in the bone or in the gum—to see which works better for children with weak enamel on their back teeth and front teeth. It may help find a pain-free way to treat these teeth.
AnkaraAges 6–12 - NCT07360392Recruiting
Nerve block comparison for knee replacement pain
This study compares two numbing techniques (nerve blocks) for pain relief after knee replacement surgery. The goal is to find which one works better and helps you recover with less pain.
AmasyaAges 18–80 - NCT07352774Enrolling by invitation
Laughter therapy for breathing and pain in older adults
This study tests whether laughter therapy can improve breathing and reduce pain in people aged 60 and older. It may be a fun, drug-free way to feel better.
Ankara, AnkaraAges 60 years+ - NCT07356115Recruiting
Pain patterns and pain location in muscle and sports clinics
This study looks at whether people's pain patterns—measured by a simple questionnaire called PainDETECT—are linked to where their pain is and what caused it. It may help doctors better understand and treat different types of pain.
IstanbulAges 18 years+ - NCT07356362Recruiting
Laser therapy for numbness and itching on the back
This trial tests whether a high-power laser can help relieve the itching, burning, and numbness on one side of the upper back caused by a condition called notalgia paresthetica. It may be an option if you have had these symptoms for at least 3 months and other causes have been ruled out.
UşakAges 18–65 - NCT07359144Recruiting
Pilates for low back pain after childbirth
This study tests whether Pilates exercises can help relieve low back pain in women who have had a baby. It focuses on pain that started after childbirth and lasts for more than three months.
Kafr ash Shaykh, KafrelsheikhAges 20–30 - NCT07359287Recruiting
Study on antibiotic use for respiratory infections
This study tests a program to help doctors prescribe antibiotics more carefully for common respiratory infections like colds, flu, bronchitis, and sinusitis. It may lead to better treatment for you.
CaenAges Any age - NCT07360028Recruiting
Nerve blocks for pain after chest surgery
This trial tests two types of numbing injections (nerve blocks) to control pain after chest surgery done with a camera. It aims to find which block works better so you can recover more comfortably.
Cairo, Abbassia-EgyptAges 25–70 - NCT07352982Recruiting
Nerve stimulation for painful periods in young women
This study tests if a gentle nerve stimulation device placed near your ankle can reduce period pain. It is for young women with primary dysmenorrhea (painful periods without a known medical cause).
Kafr ash Shaykh, KafrelsheikhAges 20–25 - NCT07356102Recruiting
Pulsed radiofrequency for pudendal nerve pain
This trial compares two types of a procedure called pulsed radiofrequency to treat chronic pain in the pudendal nerve (a nerve in the pelvic area). The goal is to find out if a higher-voltage, longer-duration treatment works better than the standard one.
AnkaraAges 18 years+ - NCT07357233Recruiting
Comparing two methods for root canal pain relief in lower molars
This trial compares two different ways of cleaning and shaping the inside of a tooth (root canal) to see which one causes less pain afterward. It is for people with a specific type of tooth infection in a lower back molar.
AlexandriaAges 18–50 - NCT07356206Recruiting
Dog-assisted therapy for fibromyalgia
This study tests whether spending time with a specially trained therapy dog can help people with fibromyalgia feel better and manage pain. You would attend 10 sessions and complete a few questionnaires.
GuimarãesAges 18 years+ - NCT07360093Recruiting
Nerve block for chronic hip pain from osteoarthritis
This study tests a nerve block treatment for people with long-term hip pain from osteoarthritis who haven't gotten enough relief from other treatments. It aims to see if this procedure can help reduce pain.
AnkaraAges 18–80 - NCT07361692Recruiting
Electric brain stimulation for complex regional pain syndrome
This trial tests if a gentle electric current applied to the scalp (called tDCS) can reduce pain in people with Complex Regional Pain Syndrome (CRPS), a chronic pain condition. It aims to see if this treatment is effective and safe for managing symptoms.
Saint-NazaireAges 18 years+ - NCT07353632Recruiting
What affects re-participation in Danish colorectal screening
This study looks at why some people come back for a second round of the Danish bowel cancer screening program after their first colonoscopy. It aims to learn what factors influence their decision to participate again.
AabenraaAges 50–75 - NCT07360847Recruiting
Understanding recovery from rotator cuff shoulder pain with non-surgical care
This study looks at people with rotator cuff shoulder pain who are starting non-surgical treatments like physical therapy. It aims to understand which factors help people get better, so doctors can provide more personalized care.
LimerickAges 18 years+ - NCT07353996RecruitingPhase 4
Finding the right dose of a new IV painkiller after bone surgery
This trial tests a single dose of a new pain medicine called tegileridine fumarate given through a vein right after orthopedic surgery (like spine, hip, or knee surgery). The goal is to find the best dose that works well for pain without causing side effects.
Hanzhong, ZhejiangAges 18–75 - NCT07361549RecruitingPhase 2
Lidocaine injection for chronic migraine pain
This study tests if injecting lidocaine (a numbing medicine) into an artery in the head can reduce chronic migraine pain. It may help people who have frequent migraines and are already getting a brain imaging test.
Camden, New JerseyAges 18 years+ - NCT05351099Recruiting
Nerve-block shot for emergency dental pain relief
This study tests whether a dental nerve-block shot can safely help reduce pain for adults who come to the emergency department with tooth pain. If the ED clinician plans to use the block, you may be asked to rate your pain during the visit.
Fresno, CaliforniaAges 18 years+ - NCT06453005Recruiting
Comparison of two tooth cap methods for baby molars
This trial compares two ways to fix cavities in baby molars: the SMART Hall technique (a newer, less invasive method) and the traditional stainless steel crown. The goal is to see which works better for children aged 3 to 9.
Tirupati, AndhrapradeshAges 3–9 - NCT06686147Recruiting
AI analysis of movement in low back pain
This trial uses artificial intelligence to analyze how well you can move if you have chronic low back pain. It may help researchers understand movement patterns better.
DenizliAges 18–65 - NCT06835868Recruiting
Registry for nerve stimulation treatments for chronic pain in Belgium
This trial creates a registry for people with chronic pain who are getting special nerve-modulating treatments in Belgium. It focuses on two specific chronic pain conditions: Persistent Spinal Pain Syndrome Type 2 (pain after spine surgery) and Complex Regional Pain Syndrome (a type of nerve pain).
Edegem, AntwerpAges Any age - NCT07351851Recruiting
Exercise for back pain and urine leakage in women
This study tests whether a special exercise program called PEMM (which combines pelvic floor and core exercises) can help women with both chronic low back pain and urinary incontinence. It is designed for women who have had back pain and urine leakage for at least 3 months.
Doha, Baladiyat ad DawhahAges 18–65 - NCT06857331Recruiting
Numbing block for pain after liver transplant
This trial tests a special numbing injection (erector spinae plane block) to help control pain after liver transplant surgery. It may be a good option if you have severe liver disease and need a transplant.
KyivAges Any age
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,578 recruiting pain medicine studies from the U.S. registry right now, out of 6,493 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.