Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,578 recruiting studies in this area right now.
By phase
- Not applicable2,954
- Phase 4240
- Phase 2129
- Phase 3103
- Phase 193
- Phase 2/Phase 337
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University84
- Cairo University59
- Beijing Tiantan Hospital34
- Tanta University33
- Ain Shams University28
- Foundation University Islamabad28
- Mayo Clinic25
- VA Office of Research and Development23
- Hacettepe University22
- Stanford University21
Where studies are running
- California151
- New York79
- Massachusetts65
- Florida64
- Texas50
- North Carolina41
- Illinois40
- Maryland39
- Ohio39
- Minnesota37
Recruiting studies3,578 total
- NCT07096349Recruiting
Chronic pain study in severe hemophilia A
This study looks at chronic pain in people with severe hemophilia A. It aims to understand pain better through questionnaires and joint health checks.
Oviedo, Principality of AsturiasAges 18 years+ - NCT07096661Enrolling by invitation
Pain education for labor and postpartum pain
This study tests a way of teaching about pain (called pain science education) to help healthcare professionals better support women during labor and after birth. If you are a healthcare professional who works with pregnant or new mothers, this trial may be for you.
BournemouthAges Any age - NCT07097792Recruiting
Concussion recovery support program for headaches
This study tests a support program for young people who have had a concussion and are still having headaches. It aims to help them recover and feel better.
Seattle, WashingtonAges 18–29 - NCT07095725Recruiting
Effect of Period Pain on Muscle Activity in Young Women
This trial studies how primary dysmenorrhea (period pain) affects muscle activity in young women aged 18-25. It may help understand why period pain happens and guide future treatments.
GizaAges 18–25 - NCT07100769Recruiting
Ultrasound guidance for epidural pain relief
This study tests if using real-time ultrasound to guide the placement of an epidural catheter improves accuracy and safety for people having major chest or belly surgery. The goal is to see if this technique reduces complications and helps ensure better pain control.
Ho Chi Minh City, Cho LonAges 16 years+ - NCT07098741Recruiting
Physical therapy for low back pain and pelvic tilt
This study looks at different physical therapy treatments for people with chronic, non-specific low back pain and a forward-tilted pelvis (anterior pelvic tilt). It aims to find which type of exercise or therapy works best to improve posture and reduce pain.
Chak Four Hundred Fifty-four, Punjab ProvinceAges 20–40 - NCT07100782RecruitingPhase 3
Estrogen & pain trial for endometriosis pelvic pain
This study tests whether a drug called relugolix CT can reduce pelvic pain from endometriosis. You'll have brain scans and pain tests to measure how your body processes pain. It might help if other treatments haven't worked well.
Ann Arbor, MichiganAges 18–49 - NCT07103317Recruiting
Understanding heart blood flow in chest pain without blockages
This study looks at people who have chest pain but don't have major blockages in their heart arteries. It aims to understand how the tiny blood vessels and artery spasms might be causing symptoms, using special heart tests.
Prague, Česká RepublikaAges 18 years+ - NCT07099560Recruiting
Comparing two numbing blocks for hypospadias repair in children
This study compares two ways to numb the lower belly and groin area for children having hypospadias repair. It tests if a newer injection method (sacral erector spinae block) works as well as the standard method (caudal block) to control pain during and after surgery.
Tanta, El-Gharbia GovenorateAges 1–5 - NCT07102121Enrolling by invitation
Comparing tooth sensitivity after cementing crowns with two dental materials
This study tests whether one type of dental cement causes less tooth sensitivity than another after placing a crown. The results could help your dentist choose the material that feels better for you.
Mingora, Khyber PakhtunkhwaAges 15–60 - NCT07102446Recruiting
Opioid safety program for chronic pain patients without cancer
This trial tests a program to help manage opioid use safely for people with chronic non-cancer pain. If you take opioids for long-term pain and do not have cancer, this study may help improve your care.
Seoul, SeoulAges 19–79 - NCT07104825Recruiting
Nerve block for pain after weight loss surgery
This trial tests if a nerve block can help control pain after gastric bypass or sleeve gastrectomy. The goal is to reduce the need for strong pain medicines and improve recovery.
Evanston, IllinoisAges 18–90 - NCT07098390Recruiting
Relaxation to Reduce Fear and Pain After Joint Replacement
This study tests whether a simple relaxation technique (progressive muscle relaxation) can help reduce fear of falling, pain, and anxiety after hip or knee replacement surgery. It may be a safe, drug-free way to feel better during recovery.
AnkaraAges 18 years+ - NCT07101172Enrolling by invitation
Stress ball for anxiety and pain during prostate biopsy
This study tests whether using a stress ball during a prostate biopsy can help reduce anxiety and pain. It may be an option if you are having your first biopsy and can squeeze a ball.
Çorum, MerkezAges 18 years+ - NCT07103135RecruitingPhase 1
Testing an accelerated TMS for chronic pain
This study tests an accelerated form of Transcranial Magnetic Stimulation (TMS) — a non-invasive treatment that uses magnetic pulses to stimulate the brain — to see if it can reduce chronic pain. If you have long-term pain that hasn't responded well to at least two medications, this trial might be a good option for you.
Minneapolis, MinnesotaAges 18 years+ - NCT07099157RecruitingPhase 4
Brivudine for Shingles: Safety and Effectiveness Study
This trial tests whether the antiviral drug brivudine is safe and effective for treating shingles (herpes zoster). It compares brivudine to other antiviral treatments like famciclovir, and may be an option if you are looking for a shorter treatment course.
BeijingAges 18 years+ - NCT07101250RecruitingPhase 4
Study of acetazolamide before laparoscopic hysterectomy
This trial tests a medication called acetazolamide given before surgery to see if it can help prevent shoulder pain after a laparoscopic hysterectomy. If you are a woman scheduled for this type of hysterectomy, you may be able to join.
Greenville, South CarolinaAges 21–65 - NCT06205875Recruiting
High vs. low dose pain block after minimally invasive heart valve surgery
This trial compares two doses of a numbing medicine injected into the chest wall to control pain after heart valve surgery. If you qualify, you will receive either a higher or lower dose of the pain block to see which provides better pain relief and recovery.
Hasselt, LimburgAges 18 years+ - NCT06970626RecruitingPhase 2/Phase 3
Comparing pain relief methods after sleeve gastrectomy
This study compares two ways to manage pain after laparoscopic sleeve gastrectomy: one uses a medication called dexmedetomidine given through an IV, and the other uses a combination of nerve blocks (TAP block and paragastric block) to see which leads to a better recovery.
AlexandriaAges 20–60 - NCT06755671Recruiting
Danning tablets for digestive symptom relief
This study looks at how well Danning tablets work for people with upset stomach, bloating, heartburn, or constipation. It follows patients who are already taking the tablets as part of their regular care.
Hangzhou, ZhejiangAges 18–75 - NCT06972199Recruiting
Foot massage or warm water bath for pain after colon cancer surgery
This trial tests whether a foot massage or a warm water foot bath can help reduce pain and improve recovery after laparoscopic surgery for colon cancer.
Istanbul, IstanbulAges 18 years+ - NCT06970678RecruitingPhase 1/Phase 2
A new way to ease pain and speed recovery after sleeve gastrectomy
This study tests whether adding two pain-management methods—a sedative infusion and a nerve block around the stomach—can help you recover faster and more comfortably after sleeve gastrectomy surgery. If you're eligible, you'll receive the extra treatment on top of standard anesthesia.
AlexandriaAges 18–60 - NCT06969417Recruiting
Comparing two medications for shingles nerve pain
This trial compares two medications (pregabalin and lacosamide) to find out which works better for relieving nerve pain that continues after shingles. If you have this persistent pain and are not already on painkillers, you may be able to join.
Kharan, Punjab ProvinceAges 18–50 - NCT06969625Recruiting
Shoulder Block for Pain Relief After Rotator Cuff Surgery
This study tests a special numbing injection (shoulder block) to see how well it controls pain after arthroscopic rotator cuff repair. If you are having this type of shoulder surgery and are generally healthy, this trial may help you recover with less pain.
Zagazig, Al SharqiaAges 21–65
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,578 recruiting pain medicine studies from the U.S. registry right now, out of 6,493 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.