Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,578 recruiting studies in this area right now.
By phase
- Not applicable2,954
- Phase 4240
- Phase 2129
- Phase 3103
- Phase 193
- Phase 2/Phase 337
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University84
- Cairo University59
- Beijing Tiantan Hospital34
- Tanta University33
- Ain Shams University28
- Foundation University Islamabad28
- Mayo Clinic25
- VA Office of Research and Development23
- Hacettepe University22
- Stanford University21
Where studies are running
- California151
- New York79
- Massachusetts65
- Florida64
- Texas50
- North Carolina41
- Illinois40
- Maryland39
- Ohio39
- Minnesota37
Recruiting studies3,578 total
- NCT07094282Recruiting
Integrative therapies study for chronic back or neck pain
This study is testing integrative medicine therapies for chronic back or neck pain. It is for military members and their families who receive care at Nellis Air Force Base. The goal is to see if these therapies can help reduce pain and improve quality of life.
Nellis Air Force Base, NevadaAges 18 years+ - NCT07093138RecruitingPhase 4
CBD cream for migraine attacks
This trial tests whether a cream made with cannabidiol (CBD) can help stop migraine attacks. It is for people aged 18 to 55 who have had migraines for at least a year and get 2 to 8 attacks per month.
TehranAges 18–55 - NCT07091682Recruiting
A trial of a dissolvable heart stent for long blockages
This trial tests a new type of stent made from magnesium that slowly dissolves over time. It is for people who have a long blockage in a heart artery that has not been treated before and may be a good option for those who are stable and have not had a recent heart attack.
ErfurtAges 18–80 - NCT06859164RecruitingPhase 2
Knee artery treatment for chronic osteoarthritis pain
This trial tests a procedure called genicular artery embolization to reduce pain in people with knee osteoarthritis that hasn't improved with other treatments. The goal is to see if blocking certain blood vessels can relieve pain and help you avoid or delay knee replacement surgery.
Chicago, IllinoisAges 40–80 - NCT07089628Recruiting
Core stability and hand-eye coordination in rotator cuff injury
This study looks at how a rotator cuff tear affects your core stability, reaction time, hand-eye coordination, pain, and daily function. It compares people with rotator cuff problems to healthy individuals to understand these connections better.
AnkaraAges 18–65 - NCT07094451Recruiting
Virtual reality for pain during needle procedures
This study tests whether using a virtual reality headset can help reduce pain during ultrasound-guided needle procedures in pregnancy. It may offer a drug-free way to feel more comfortable during the procedure.
New York, New YorkAges 18 years+ - NCT07095556Recruiting
Laser therapy to help gums heal after tooth extraction
This trial tests whether a special laser treatment can help your gums heal better after a tooth is removed and the socket is prepared for a future dental implant. If you're having a tooth pulled and bone preservation, this laser might speed up healing and reduce pain.
Charleston, South CarolinaAges 18 years+ - NCT07094178Recruiting
Steroid vs PRP shots for shoulder tendon pain
This trial compares two treatments for shoulder tendinopathy: a corticosteroid shot or a platelet-rich plasma (PRP) injection. It aims to find which one works better to relieve pain and improve function.
TunisAges 18 years+ - NCT07091123RecruitingPhase 4
Comparing two treatments for chronic back pain after surgery
This study compares two treatments for long-term back pain after surgery: a spinal cord stimulator (a device that sends mild electrical pulses to your spine) and a pump that delivers pain medicine directly to your spinal fluid. It will look at which treatment you prefer and how well it works over time.
Cleveland, OhioAges 30 years+ - NCT07094997Recruiting
Massage therapy for healthcare workers with low back pain
This study tests if massage therapy can help healthcare workers with ongoing low back pain. If you qualify, you would receive several massage sessions to see if they reduce your pain and improve your well-being.
Wroclaw, Lower Silesian VoivodeshipAges 30–65 - NCT07089134Recruiting
Virtual reality for ICU patient satisfaction and recovery
This trial tests whether using virtual reality (wearing a headset to see calming scenes) helps people in the ICU feel better, recover faster, and be more satisfied with their care. It is for awake and stable ICU patients who can follow simple instructions.
São Paulo, São PauloAges 18 years+ - NCT07090356Recruiting
Soft tissue therapy versus stretching for athletes with piriformis syndrome
This study compares two techniques—instrument-assisted soft tissue mobilization and PNF stretching—to see which works better for reducing pain and improving movement in athletes with piriformis syndrome. It may help if you are an athlete with ongoing buttock or hip pain that makes sitting uncomfortable.
Lahore, Punjab ProvinceAges 18–35 - NCT07093905Recruiting
Comparing two anesthetics for rotator cuff repair surgery
This study compares two types of anesthesia (numbing medicine) for rotator cuff repair surgery. It will help find which method works better for pain control and recovery.
MarseilleAges 18 years+ - NCT07090928RecruitingPhase 4
Numbing medicine for less pain after knee scope surgery
This study tests whether giving bupivacaine (a numbing medicine) around the time of knee arthroscopy can reduce pain at the surgery sites and help you move your knee better after the operation.
Peshawar, KPKAges 18–70 - NCT07090122Recruiting
Spinal tumor treatment: ablation plus radiation vs radiation alone
This study compares two treatments for cancer that has spread to the spine. One group receives radiofrequency ablation (a heat-based treatment to destroy tumor cells) plus bone strengthening, followed by radiation. The other group receives radiation alone. The goal is to see which approach better controls pain and prevents spine problems.
Minneapolis, MinnesotaAges 18 years+ - NCT07088900Recruiting
Dexmedetomidine with bupivacaine for pain relief in children's appendix surgery
This trial tests if adding dexmedetomidine to bupivacaine (a numbing medicine given near the tailbone) provides better pain relief during and after appendix surgery in children. It may help reduce the need for other pain medicines.
CairoAges 2–7 - NCT07095036Recruiting
Spinal cord stimulation and sensation study
This study looks at how a spinal cord stimulator affects your sense of touch and movement. It may help doctors better understand how this device works for people with chronic pain.
Chapel Hill, North CarolinaAges 18–85 - NCT07092982Recruiting
Comparing two numbing methods for knee replacement surgery
This study compares two different numbing techniques to see which provides better pain control during and after total knee replacement. It may help find a way to reduce pain and improve recovery.
IstanbulAges 18–75 - NCT07090096Recruiting
Plant-based diet study for endometriosis pain
This study tests whether a plant-based diet can help reduce pelvic pain in women with endometriosis. Participants are randomly assigned to either follow a plant-based diet or continue their usual diet for several months.
La Jolla, CaliforniaAges 18–45 - NCT07093437Recruiting
Comparing ways to secure urinary catheters in ICU patients
This study compares two methods of securing a urinary catheter to the thigh to see which works better. It's for patients in the intensive care unit (ICU) who need a catheter for more than 48 hours.
BarcelonaAges 18–99 - NCT07088146RecruitingPhase 4
Dexamethasone to prolong spinal anesthesia in C-section
This study tests whether giving dexamethasone (a steroid) during spinal anesthesia can make the numbness last longer during a planned C-section. It may help reduce the need for extra pain medicine after surgery.
Rawalpindi, Punjab ProvinceAges 16–40 - NCT06347679Recruiting
Can aromatherapy ease anxiety and pain during dental work?
This study tests whether smelling certain essential oils (aromatherapy) can help reduce anxiety and pain during dental treatments. If you are an adult having a dental procedure, this may be a way to feel more comfortable without medication.
Chengdu, SichuanAges 18–40 - NCT06552936Recruiting
Laser therapy for faster healing after tooth extraction
This study tests whether using a special laser after a lower-jaw tooth extraction can help the socket heal faster and grow new bone. It may benefit people who plan to get a dental implant later.
Lahore, Punjab ProvinceAges 21 years+ - NCT06974552Recruiting
Support surfaces during robotic pelvic surgery
This trial compares different support surfaces for patients having robotic surgery in the lower pelvic area while in a steep head-down position. It aims to see which surface helps prevent skin injuries.
Istanbul, AtaşehirAges Any age
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,578 recruiting pain medicine studies from the U.S. registry right now, out of 6,493 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.