Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,611 recruiting studies in this area right now.
By phase
- Not applicable3,768
- Phase 2217
- Phase 4200
- Phase 1182
- Phase 3139
- Phase 1/Phase 271
- Phase 2/Phase 334
Top conditions
- Knee Osteoarthritis172
- Rheumatoid Arthritis132
- Fibromyalgia105
- Osteoporosis82
- Osteoarthritis71
- Rheumatoid Arthritis (RA)68
- Osteoarthritis, Knee64
- Shoulder Pain48
- Hip Osteoarthritis43
- Psoriatic Arthritis40
- Degenerative Disc Disease39
- Chronic Pain38
- Total Knee Arthroplasty38
- Duchenne Muscular Dystrophy37
- Systemic Lupus Erythematosus37
- Musculoskeletal Pain35
- Osteoarthritis (OA) of the Knee32
- Pain32
Leading sponsors
- Riphah International University85
- Istituto Ortopedico Rizzoli69
- Cairo University65
- Assistance Publique - Hôpitaux de Paris36
- Foundation University Islamabad31
- Mayo Clinic28
- Massachusetts General Hospital25
- National Taiwan University Hospital25
- Hacettepe University23
- Tanta University22
Where studies are running
- California207
- New York87
- Florida82
- Maryland76
- Arizona72
- Massachusetts71
- Texas67
- Alabama59
- Illinois51
- Pennsylvania48
Recruiting studies4,611 total
- NCT07555067Enrolling by invitation
Robotic Knee Replacement Surgery Comparison
This trial compares two different robotic systems used during knee replacement surgery for knee arthritis (wear and tear). The study helps doctors understand which robotic system may provide better results.
Bydgoszcz, Kuyavian-Pomeranian VoivodeshipAges 18 years+ - NCT07556874Recruiting
Study of Surgeries for Multiple Bone Tumors
This research looks at surgery records from patients who had multiple osteochondromas (benign bone tumors) treated at a major orthopedic hospital. The study aims to understand what surgical approaches work best for this condition.
Bologna, BolognaAges Any age - NCT07553351RecruitingPhase 3
Growth hormone treatment for children with growth hormone deficiency
This trial tests a new growth hormone medicine (GB06) for children whose bodies don't make enough growth hormone naturally. The study will see if this treatment helps children grow taller over time.
Chengdu, SichuanAges 3–11 - NCT07554495RecruitingPhase 3
Filgotinib for moderate to severe polyarticular juvenile arthritis
This trial tests filgotinib, a new medication that may help reduce joint swelling and pain in children and teens (ages 8–17) with polyarticular juvenile idiopathic arthritis—a type of childhood arthritis affecting multiple joints. You're eligible if your current arthritis medicines haven't worked well enough.
LeuvenAges 8–18 - NCT07558590Recruiting
Shoulder Replacement System Recovery and Function Study
This study follows patients who have received a new shoulder replacement device to see how well it works and how patients recover. Researchers will collect information about your shoulder function and satisfaction over time.
AmiensAges 18 years+ - NCT07557459Recruiting
Checking the health of dental implants
This study looks at how dental implants (artificial tooth roots) are doing, especially around the gum and bone, to help keep them healthy. If you have implants that have been in place for at least 3 years, you may be able to join and get a thorough check-up.
A Coruña, A CoruñaAges Any age - NCT07558278RecruitingPhase 4
LINQ procedure vs standard care for sacroiliac joint pain
This study compares a new procedure called LINQ—which stabilizes the sacroiliac joint (the joint where your spine connects to your pelvis)—against standard pain management for chronic sacroiliac joint pain. The trial tests whether this procedure reduces pain and disability better than medications and physical therapy alone.
Shenandoah, TexasAges 21 years+ - NCT07551804RecruitingPhase 2
Growth hormone replacement therapy safety and effectiveness study
This study tests a new injectable growth hormone treatment for adults whose bodies don't produce enough growth hormone naturally. Researchers will measure how safe it is, how your body processes it, and whether it helps you feel better and function more normally.
BeijingAges 18–80 - NCT07553182RecruitingPhase 3
Continuing filgotinib treatment for juvenile arthritis
This study lets young people who benefited from filgotinib (a medication that reduces inflammation) in a previous trial continue taking it to see if it stays safe and effective over a longer period. It's designed for patients ages 8–17 who did well on this medicine before.
Le Kremlin-BicêtreAges 8–18 - NCT07557446RecruitingPhase 2
Testing AGA2115 for Osteogenesis Imperfecta in Chinese Patients
This study tests a new medicine called AGA2115 in adults and teenagers with osteogenesis imperfecta (brittle bone disease). The trial aims to find the right dose and see if it can strengthen bones and reduce fracture risk.
Beijing, Beijing MunicipalityAges 12–75 - NCT06732674Recruiting
Home-based care for lung disease in rheumatic conditions
This trial tests whether people with lung disease caused by a rheumatic condition can safely manage their care at home using a smartphone or tablet. It aims to see if home monitoring is as effective as in-person visits for keeping your lungs healthy.
OsloAges 18 years+ - NCT07547215Recruiting
TRAQ Minimally Invasive Sacroiliac Joint Fusion Study
This study tests a minimally invasive surgical procedure called TRAQ to treat chronic sacroiliac joint (SIJ) pain—a type of lower back and buttock pain. The procedure may help if you've had pain for at least 6 months that didn't improve with non-surgical treatments and have already benefited from diagnostic joint injections.
Tucson, ArizonaAges 21 years+ - NCT07543796RecruitingPhase 2
Pain Relief After Hip Replacement Surgery
This study tests whether a new pain medication called TRD205 works well and is safe for people recovering from hip replacement surgery. If it works, it could offer better pain control after your operation.
Guangzhou, GuangdongAges 18–80 - NCT07543302Enrolling by invitation
Can Ear Nerve Stimulation Reduce Inflammation in Duchenne Muscular Dystrophy?
This trial tests whether gently stimulating a nerve in the ear can lower inflammation levels in boys with Duchenne muscular dystrophy (DMD). The goal is to see if this non-invasive approach might help slow disease progression or ease symptoms.
StockholmAges 5–17 - NCT07546552Recruiting
Egg Development Study: Testing a New Hormone Signal
This research study looks at how a specific hormone signal affects egg development in the ovary. Researchers are trying to understand if changing this signal might improve egg quality or fertility outcomes.
Skive, Midt JyllandAges 18 years+ - NCT07544732Recruiting
Tape comparison for heel pain relief
This study tests two types of taping methods to reduce heel pain caused by plantar fasciitis. You'll wear special tape on your foot for a few weeks to see which method works better for your pain and movement.
Islamabad, Punjab ProvinceAges 19–44 - NCT07543016Recruiting
Amino Acids and Exercise for FSHD Muscle Weakness
This study tests whether amino acid supplements combined with exercise can help people with FSHD (a genetic muscle disease) build strength and reduce fatigue. Researchers will compare participants who receive amino acids plus exercise training to a control group.
Voghera, PaviaAges 18–50 - NCT07543484Recruiting
Tennis Serve Movement Study for Shoulder Pain
This research study examines how your shoulder muscles and joints move during a tennis serve, comparing players with shoulder pain to those without. The goal is to better understand shoulder injuries in tennis and help prevent or treat them.
TaipeiAges 18–40 - NCT07544823Recruiting
Study of Early Markers for Osteoarthritis
This study looks for early signs of osteoarthritis (joint wear and tear) in your blood or other samples. Understanding these markers may help doctors detect and treat osteoarthritis sooner.
Xinxiang, HenanAges 40–70 - NCT07545616Recruiting
Finding biomarkers for femoral head bone death
This study looks for biological signs (biomarkers) that can help identify and understand osteonecrosis of the femoral head—a condition where bone in the hip dies. Researchers hope these signs will improve how doctors diagnose and treat the condition.
Xinxiang, HenanAges 18–70 - NCT07546240Recruiting
Radiation therapy for persistent heel pain
This trial tests whether targeted radiation can relieve long-lasting heel pain (plantar fasciitis) that hasn't improved with other treatments. If your heel pain has lasted months and other options haven't worked, radiation might help reduce pain and improve walking.
GliwiceAges 40 years+ - NCT07550647Recruiting
Early Rehab Program After Hip Replacement Surgery
This study tests a rehabilitation program that starts soon after hip replacement surgery for arthritis or hip developmental issues. The program uses telehealth (video calls) to help you recover strength and mobility at home.
Niğde, MerkezAges 50–75 - NCT07547735RecruitingPhase 2
Stem Cell Treatment for Knee Osteoarthritis
This study tests whether special stem cells (called UC-MSCs, derived from umbilical cord tissue) can reduce pain and improve function in people with moderate knee osteoarthritis. Researchers will inject these cells into your knee to see if they help repair damaged cartilage and reduce inflammation.
WuhanAges 40–70 - NCT07543692Recruiting
Ultrasound-guided injection therapy for spine pain
This study tests whether using ultrasound imaging to guide a special injection treatment (pharmacopuncture) is safe and effective for people with spine-related neck or lower back pain that radiates into the arms or legs. The treatment is already being offered as routine care, and this study tracks how well it works.
Daejeon, DaejeonAges 19–69
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,611 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,492 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.