Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,841 recruiting studies in this area right now.
By phase
- Not applicable3,975
- Phase 2223
- Phase 4196
- Phase 1191
- Phase 3149
- Phase 1/Phase 274
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis185
- Rheumatoid Arthritis142
- Fibromyalgia102
- Osteoporosis88
- Osteoarthritis74
- Osteoarthritis, Knee72
- Rheumatoid Arthritis (RA)64
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Chronic Pain38
- Degenerative Disc Disease38
- Total Knee Arthroplasty38
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University110
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad34
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California210
- New York94
- Florida80
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois54
- Pennsylvania50
Recruiting studies4,841 total
- NCT07549542Enrolling by invitationPhase 4
Testing antibiotic delivery method for hip replacement surgery
This study compares a new way of delivering antibiotics directly into the bone during hip replacement surgery versus the standard IV method. The goal is to see if this approach prevents infection just as well while potentially improving outcomes.
Somerset, New JerseyAges 18 years+ - NCT06732167Recruiting
Lyoplant for bone regrowth in dental implant surgery
This trial tests a special membrane called Lyoplant® that helps your jawbone grow back around a new dental implant. If you need a dental implant and your jawbone has a small gap or defect, this study might be a good fit for you.
Barcelona, CataloniaAges 18 years+ - NCT06636045Enrolling by invitation
Blood flow restriction after ACL surgery with quad graft
This study tests whether using a special blood flow restriction cuff after ACL surgery helps you recover faster and stronger. It is for people having ACL reconstruction using their own quadriceps tendon for the first time.
Kansas City, KansasAges 14–40 - NCT07574229Recruiting
Support System for Teens Wearing Scoliosis Braces
This study tests a new computer-based support system designed to help teenagers stay motivated and consistent with wearing their prescribed scoliosis braces. The system uses interactive tools and feedback to make brace-wearing easier and more manageable.
Shanghai, Shanghai MunicipalityAges 10–18 - NCT07329426Recruiting
Muscle energy therapy with mobilization for sacral torsion
This trial tests if combining muscle energy therapy with spinal mobilization can relieve pain and correct misalignment in people with a twisted pelvic bone (sacral torsion). It may help reduce pain and improve mobility.
Islamabad, Punjab ProvinceAges 22–44 - NCT07228611Recruiting
Osteoporosis risk after stroke
This study looks at bone health in people who have had a stroke. It aims to find out who is at risk for weak bones (osteoporosis) after a stroke, so doctors can help prevent fractures.
Ankara, YenimahalleAges 55–85 - NCT05767164Recruiting
Study links surgery outcomes to test results in cervical spine disease
This study looks at how measurements from symptoms, exams, and MRI results relate to recovery after a specific type of neck surgery (“single open-door” surgery). It may help doctors better predict who is more likely to do well after this operation.
Xi'an, Shannxi ProvinceAges 18–86 - NCT06527482Recruiting
Using your own bone and cartilage to repair ankle damage
This trial tests a surgery that takes a small piece of bone and cartilage from your knee and transplants it to a damaged area in your ankle. It may help people with severe ankle cartilage injuries that haven't gotten better with other treatments.
BeijingAges 18–60 - NCT06601803Enrolling by invitationPhase 4
Surgical preparation study for first-time shoulder replacement
This trial tests a surgical prep solution called Surgiphor during first-time total shoulder replacement. It aims to help prevent infections.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07226388Enrolling by invitation
Pyrocarbon hemiarthroplasty vs total shoulder replacement for osteoarthritis
This study compares two types of shoulder replacement surgery for people with osteoarthritis: one that replaces only the ball of the joint (hemiarthroplasty with a pyrocarbon ball) and one that replaces both the ball and socket (total shoulder arthroplasty). The goal is to see which option works better for people with this condition.
St Louis, MissouriAges 40–65 - NCT06797414Recruiting
Pilates with or without vibration for upper cross syndrome
This study compares Pilates exercises with and without whole-body vibration (a platform that gently shakes your body) to see which better improves posture and pain in people with upper cross syndrome (a common pattern of rounded shoulders and forward head). It aims to find a more effective way to strengthen muscles and reduce discomfort.
Lahore, Punjab ProvinceAges 20–40 - NCT07217964Enrolling by invitation
Study of natural protein for spinal fusion surgery
This trial is testing a natural protein material used during spinal fusion surgery to treat lower back pain caused by worn-out discs. It may help patients who haven't gotten better with other treatments and need surgery on up to four levels of the lower spine.
New York, New YorkAges 18 years+ - NCT07217405RecruitingPhase 4
Radiation or steroid shot for hand osteoarthritis pain
This trial compares low-dose radiation therapy to a corticosteroid injection to see which works better for hand osteoarthritis pain. It's for people 50 and older with moderate to severe hand OA who have significant pain when using their hand.
Rochester, MinnesotaAges 50 years+ - NCT07215845Recruiting
Healing spinal bone stress with MRI monitoring
This study uses MRI scans to see how well a spinal stress injury (called a pars defect) heals over time. It might help if you are a young person with low back pain from a specific type of bone stress in the lower spine.
Columbia, MissouriAges 12–30 - NCT07216300Enrolling by invitation
Osteopathic treatment for baseball pitchers
This trial tests if osteopathic manipulation of the shoulder and hip can improve pitching performance in college baseball players. It may help you throw better and prevent injuries.
Hattiesburg, MississippiAges 18–102 - NCT06107959Recruiting
Metabolism changes after bone or joint surgery
This study measures how your metabolism (how fast your body burns energy) changes after orthopedic surgery (surgery on bones or joints). It may help doctors understand how to better support recovery.
Kansas City, KansasAges 15 years+ - NCT06446414Enrolling by invitation
Provincial Scale-Up of Choose to Move Program
This trial looks at how well the Choose to Move (CTM) program works when it is expanded across a province. Researchers want to see if it helps older adults stay active and whether the program is being delivered as planned.
Vancouver, British ColumbiaAges 50 years+ - NCT06532929Recruiting
Recovery after sports surgery with Teknimed products
This study is checking how well people recover after sports surgery using Teknimed products. It is for patients who had or will have a surgery with these products, and aims to see how the products perform in real life.
Aubenas, ArdècheAges 18 years+ - NCT06839807Recruiting
Testing a new device for knee replacement loosening
This study tests a new device (AtMoves Knee System) to help diagnose if a knee replacement is loose. It is for people who have had a knee replacement and have symptoms that might mean the implant is loose, but standard tests have not given a clear answer.
Nijmegen, GelderlandAges 18 years+ - NCT06831422Recruiting
Antimicrobial Wash During Shoulder Replacement
This study tests whether washing the surgical site with a special antimicrobial liquid after the incision can lower the risk of infection during shoulder replacement surgery. It may help people who are already planning a first-time shoulder replacement.
Detroit, MichiganAges 18 years+ - NCT07211464Recruiting
ACT plus exercise for older adults with chronic low back pain
This study tests whether combining acceptance and commitment therapy (ACT) with exercise helps older adults manage ongoing low back pain. If you've had pain for at least 3 months and it's been bothering you, this approach might teach you new ways to cope and move better.
Hong KongAges 60 years+ - NCT07003087Enrolling by invitation
AI gait analysis for shoe sole adjustments
This study uses a 2D video and AI to analyze how you walk. The goal is to adjust your shoe soles to help with discomfort in your legs or feet.
TaichungAges 20–70 - NCT07706244Recruiting
Does reducing pre-surgery anxiety help orthopedic patients recover better?
This study tests if a program to reduce anxiety before surgery (Enhanced Recovery After Surgery) improves how patients feel one year after major orthopedic surgery like knee, hip, or spine procedures, compared to standard care.
Hualien City, Hualien CountyAges 20–100 - NCT04875884Recruiting
MRI imaging study for people with a replaced hip
This trial uses an MRI scan to improve how hip replacements are imaged, especially in people with hip pain. It may help clinicians see what’s going on around the hip implant more clearly.
New York, New YorkAges 18–99
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,841 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,937 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.