Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,610 recruiting studies in this area right now.
By phase
- Not applicable3,771
- Phase 2215
- Phase 4199
- Phase 1182
- Phase 3139
- Phase 1/Phase 270
- Phase 2/Phase 334
Top conditions
- Knee Osteoarthritis171
- Rheumatoid Arthritis131
- Fibromyalgia105
- Osteoporosis82
- Osteoarthritis71
- Rheumatoid Arthritis (RA)68
- Osteoarthritis, Knee65
- Shoulder Pain48
- Hip Osteoarthritis43
- Psoriatic Arthritis40
- Degenerative Disc Disease39
- Chronic Pain38
- Total Knee Arthroplasty38
- Systemic Lupus Erythematosus37
- Duchenne Muscular Dystrophy36
- Musculoskeletal Pain35
- Osteoarthritis (OA) of the Knee32
- Pain32
Leading sponsors
- Riphah International University85
- Istituto Ortopedico Rizzoli69
- Cairo University66
- Assistance Publique - Hôpitaux de Paris36
- Foundation University Islamabad31
- Mayo Clinic28
- Massachusetts General Hospital25
- National Taiwan University Hospital25
- Hacettepe University23
- Tanta University22
Where studies are running
- California207
- New York87
- Florida82
- Maryland76
- Arizona72
- Massachusetts71
- Texas66
- Alabama60
- Illinois51
- Pennsylvania48
Recruiting studies4,610 total
- NCT07511751Recruiting
Comparing treatments for myofascial pain syndrome
This trial compares three different treatments to find which works best for long-term back pain caused by myofascial pain syndrome, a condition where tight muscle knots cause pain. It is for people who have not found relief with standard treatments.
Adapazarı, SakaryaAges 18–65 - NCT07509775Recruiting
Chinese medicine and Western medicine for Ankylosing Spondylitis
This study tests if combining traditional Chinese medicine with standard Western medicine can better treat ankylosing spondylitis. The goal is to see if this approach can reduce inflammation and improve your symptoms, such as back pain and stiffness.
Beijing, Beijing, ChinaAges 18–75 - NCT07513350Recruiting
Exercise and anti-fibrotic treatment for frozen shoulder
This study tests whether exercise combined with an anti-fibrotic medication (a drug that reduces scar tissue) helps people with frozen shoulder regain shoulder movement. Frozen shoulder causes stiffness and pain that limits your ability to move your arm.
IstanbulAges 18 years+ - NCT07507734Recruiting
Splint and exercise therapy for jaw joint pain
This trial tests whether a custom mouth splint combined with jaw exercises can reduce pain in the jaw joint (TMJ). It may help people who have had jaw joint pain for at least 3 months.
Istanbul, TuzlaAges 18–65 - NCT07514819Recruiting
Adaptive Proton Therapy Planning for Children With Cancer
This study tests a new way to plan proton radiation therapy (a precise type of cancer treatment) for children with solid tumors or Hodgkin's lymphoma. The goal is to improve how doctors adapt treatment during therapy to better target tumors while protecting healthy tissue.
Memphis, TennesseeAges Any age - NCT07512934Recruiting
Pancreatic Function Study in Early Type 2 Diabetes
This study examines how the pancreas works in people newly diagnosed with type 2 diabetes. Researchers will assess pancreatic function to better understand early diabetes and potentially improve treatment.
Aktobe, AktobeAges 18–74 - NCT06719037Recruiting
Comparing two spine surgeries for lower back narrowing
This study compares two different surgical techniques – one using a small camera (endoscopic discectomy) and the other a traditional open approach (microdiscectomy) – to treat narrowing in the lower spine. It helps find which method may be better for relieving pain and improving function.
Jinan, ShandongAges 18–80 - NCT06753565RecruitingPhase 2
L-carnitine supplement for rheumatoid arthritis
This trial tests whether adding L-carnitine (a natural substance) to your current treatment helps reduce rheumatoid arthritis symptoms. It could be an option if your arthritis is still active despite taking standard medications.
Cairo, DemerdashAges 18–60 - NCT06761040Recruiting
Hip and foot strength training for overweight women
This study tests whether adding hip-strengthening exercises to foot-strengthening exercises helps overweight women with flat feet. If you have foot pronation and are in your early 30s, you may be able to join.
Lahore, Punjab ProvinceAges 30–35 - NCT06760884Recruiting
Pregnancy and jaw function study
This study looks at jaw joint function, oral habits, and pain in pregnant and non-pregnant women. It aims to understand how pregnancy might affect these issues.
TrabzonAges 18–45 - NCT07499362RecruitingPhase 2
Study of Pimicotinib for Japanese Patients with TGCT
This trial tests a new drug called pimicotinib for people in Japan with tenosynovial giant cell tumor (TGCT) that cannot be removed by surgery. It aims to see if the drug can help with pain and stiffness caused by the tumor.
ChūōkuAges 18 years+ - NCT06763419Recruiting
Light therapy for jaw joint pain
This trial tests if a non-invasive light therapy (photobiomodulation) can reduce pain and clicking in the jaw joint. It may help people with jaw pain caused by muscle tension or joint issues.
AlexandriaAges 20–40 - NCT06763601Recruiting
Shoulder treatment for frozen shoulder
This trial tests a new shoulder exercise method for frozen shoulder. If you are between 40–65 years old and have been diagnosed with frozen shoulder, you may be able to join.
AjmanAges 40–65 - NCT06763679Recruiting
Comparing two therapies for frozen shoulder pain
This trial tests whether adding a specific joint mobilization technique to a standard muscle-relaxing method works better for people with frozen shoulder. It aims to help improve shoulder movement and reduce pain.
Lahore, Punjab ProvinceAges 50–60 - NCT07501507RecruitingPhase 2/Phase 3
Methotrexate for hand osteoarthritis not helped by usual treatments
This trial tests if methotrexate, a medicine that reduces inflammation, can ease pain and improve function in people with hand osteoarthritis that hasn't gotten better with standard treatments like pain relievers or hand therapy.
NiceAges 40–85 - NCT07500883Recruiting
Adding body awareness therapy to scoliosis exercises for teens
This trial tests whether adding Basic Body Awareness Therapy (a gentle movement practice that helps you notice how your body feels and moves) to standard scoliosis exercises can improve posture and reduce discomfort in teenagers with scoliosis.
Ankara, AnkaraAges 10–17 - NCT07499973Recruiting
Core muscle strength and knee stability for injury prevention
This study looks at how your core (abdominal muscles) affects knee stability. It will test a training program to see if it helps prevent injuries. You will be randomly assigned to either the training group or a control group for 8 weeks.
Villaviciosa de Odón, MadridAges 18–35 - NCT07501429RecruitingPhase 1
Shockwave therapy for arm spasticity after spinal cord injury
This trial tests whether shockwave therapy can reduce muscle tightness in the elbow and wrist caused by spinal cord injury. It may help make daily tasks like dressing or bathing easier.
West Orange, New JerseyAges 18 years+ - NCT07507175Recruiting
Calf muscle release for women with knee arthritis
This trial tests whether releasing tight calf muscles can help women with knee osteoarthritis feel less pain. It focuses on women who have moderate knee arthritis and a tight spot in their calf muscle.
Giza, Giza GovernorateAges 45–55 - NCT07502989Recruiting
Study of Muscle Health Using Electrical Impedance Myography
This study uses a simple electrical test (EIM) and an MRI scan to check muscle health in people with muscle diseases. It may help researchers learn how to measure muscle changes without a biopsy.
Boston, MassachusettsAges 18–89 - NCT07501013Recruiting
Shoulder and knee surgery outcomes study
This study looks at how well different types of shoulder and knee surgeries work for sports injuries. It aims to help improve future care by following patients' recovery after common procedures like fixing torn cartilage or repairing ligaments.
Hangzhou, ZhejiangAges 8–80 - NCT07505914Recruiting
Breathing exercises for better thinking in older adults
This trial tests whether simple breathing exercises can improve memory and thinking skills in adults aged 65 and older. You would attend two sessions each week for 8 weeks.
IstanbulAges 65 years+ - NCT07503327Recruiting
Remote rehab for ankylosing spondylitis
This trial tests whether doing physical therapy exercises at home using a smartphone app can help people with ankylosing spondylitis feel better and move more easily.
ElâzığAges 16–65 - NCT07502209Recruiting
Two types of nerve treatment for chronic shoulder pain
This study compares two methods of treating chronic shoulder pain by using a needle to deliver a special type of electrical pulse to a nerve in the shoulder. The goal is to find which method provides better pain relief for people with shoulder pain from a rotator cuff problem.
AnkaraAges 40–80
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,610 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,508 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.