Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,841 recruiting studies in this area right now.
By phase
- Not applicable3,975
- Phase 2223
- Phase 4196
- Phase 1191
- Phase 3149
- Phase 1/Phase 274
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis185
- Rheumatoid Arthritis142
- Fibromyalgia102
- Osteoporosis88
- Osteoarthritis74
- Osteoarthritis, Knee72
- Rheumatoid Arthritis (RA)64
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Chronic Pain38
- Degenerative Disc Disease38
- Total Knee Arthroplasty38
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University110
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad34
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California210
- New York94
- Florida80
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois54
- Pennsylvania50
Recruiting studies4,841 total
- NCT06820073Recruiting
Stretching study for office workers with neck or back pain
This study tests if a gentle stretching method using a special hammock can help reduce neck and back discomfort for people who sit at work. It's looking for volunteers who have some aches but no serious diagnoses.
Zaragoza, ZaragozaAges 18–65 - NCT07208630Recruiting
Mobilization therapy for seniors' movement and thinking
This trial tests a hands-on therapy called instrument-assisted soft tissue mobilization to see if it improves how well you move and think. It may help seniors who struggle with balance or memory.
GizaAges 65–75 - NCT06534866Recruiting
Kinesio tape plus therapy for plantar fasciitis
This study tests whether adding kinesio tape (a stretchy therapeutic tape) to standard physical therapy can reduce heel pain, improve ankle motion, and help you walk better. It is for people with plantar fasciitis who haven't had recent injections or surgery.
Rawalpindi, Punjab ProvinceAges 20–40 - NCT07209033Recruiting
Testing FlexiOss for bone repair in leg and foot fractures
This trial tests a new material called FlexiOss to help heal broken bones in the leg or foot. It aims to see if the material is safe and effective for bone regeneration.
KrakowAges 18–75 - NCT05872191Enrolling by invitation
Spanish-language tests for arm function after stroke
This study checks whether two hand/arm assessment questionnaires and tests work well in Spanish for people living with stroke-related arm weakness. It mainly involves you doing standardized assessments if you’re eligible.
Valencia, ValenciaAges 18–80 - NCT06535633Recruiting
Exercise program for older adults with chronic pain
This study looks at whether a community exercise program can help older adults with long-term muscle or joint pain. It is designed for people who are not already active and want to try a gentle, guided exercise program.
LimerickAges 50 years+ - NCT03610789Enrolling by invitation
Follow-up study for a specific hip implant system
This study monitors people who already received a specific hip replacement device (REDAPT) to check how it’s doing over time. It may help confirm long-term safety and performance of these implant parts.
Rancho Mirage, CaliforniaAges 18 years+ - NCT07206797Recruiting
Ultrasound to measure muscle activity from spinal cord stimulation
This study uses ultrasound to see how muscles respond to two types of electrical stimulation (spinal cord and functional electrical stimulation). It may help researchers better understand how to treat muscle weakness or paralysis.
Raleigh, North CarolinaAges 18–60 - NCT06536582Recruiting
Nutrition’s role in PRGF treatment for shoulder tendon pain
This trial studies how diet affects the success of a special blood-based treatment (PRGF) for shoulder tendon pain. It may help you heal better from tendinopathy.
MilanAges 18–70 - NCT06843798Recruiting
Healthcare workers' ergonomic knowledge and muscle pain
This study looks at how healthcare workers' understanding of ergonomics relates to muscle and bone problems. It may help find ways to prevent work-related pain.
IstanbulAges 25–45 - NCT06796881Recruiting
Comparison of two therapies for long-term low back pain
This study compares two hands-on treatments for people with chronic low back pain. One uses special tools to massage tight muscles, while the other uses gentle pressure on muscle knots. Both aim to help you move better and feel less pain.
CairoAges 25–45 - NCT06859957RecruitingPhase 3
Melatonin for chronic low back pain
This trial tests if melatonin can help reduce chronic low back pain. If you have had low back pain for at least 3 months that limits your daily activities, this study might be for you.
RotterdamAges 18–65 - NCT04812730Recruiting
Study of spinal alignment in adults with posture problems
This study measures how your spine and pelvis line up in everyday standing and walking, using multiple types of measurements. It aims to better understand adult spinal deformity and how it affects body mechanics—information that may help plan future care.
Leuven, Vlaams-BrabantAges 18–79 - NCT05560477RecruitingPhase 1/Phase 2
Study drug to help meniscus tears heal after knee injury
This early-phase study tests whether AM3101 can improve healing of a meniscus tear in the knee. Participants must meet age, scan, and health-lab requirements, and they will be closely followed during recovery to check safety and benefit.
Cincinnati, OhioAges 18–40 - NCT06849934Enrolling by invitation
Testing software for knee movement in below-knee amputees
This study tests whether a computer program called Kinovea can accurately measure how your knee moves while walking. If you have a below-knee amputation, use a prosthetic, and meet a few health criteria, you may be able to help improve how amputees are fitted and trained.
AnkaraAges 18–65 - NCT06915896Recruiting
Chronic back or neck pain: predicting therapy outcomes
This study looks at people with long-term low back or neck pain who are waiting for physical therapy. It aims to find what factors predict how well they will do with different treatment paths.
Florence, FIAges 18 years+ - NCT06046859RecruitingPhase 4
Can fluoxetine help recovery after serious injuries?
This study tests whether giving the antidepressant fluoxetine (Prozac) right after a traumatic injury can help improve mental and physical recovery. It is for people who have broken bones or internal injuries from an accident and may be feeling down.
Gainesville, FloridaAges 18–85 - NCT06741956Enrolling by invitation
Wearable device for osteoporosis prevention in women
This trial tests a wearable device designed to help prevent osteoporosis and reduce fracture risk in women who have recently gone through menopause. The goal is to see if the device can help you stay active and lower your chances of breaking a bone.
Seville, SpainAges 40 years+ - NCT06423300Recruiting
Testing a new implant for kneecap cartilage damage
This trial tests a new implant called the Patellar LIFT System to treat pain caused by cartilage damage behind the kneecap. It is for people who have tried other treatments like physical therapy but still have significant knee pain.
La Mesa, CaliforniaAges 22–65 - NCT07188350Recruiting
Electrical muscle stimulation for patients on a breathing machine
This trial tests whether low-level electrical pulses to the leg muscles can help prevent weakness in patients who need a breathing tube (ventilator) for more than 48 hours. It aims to see if this treatment helps patients recover faster.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT06523842Enrolling by invitation
Arabic version of a muscle pain questionnaire test
This study tests a translated questionnaire that measures muscle and joint pain in the neck, shoulders, back, and arms. It asks Arabic-speaking workers to fill out the form to see how well it works.
Dokki, Giza GovernorateAges 18–60 - NCT07185802Recruiting
PRP injection for recent ACL injury
This trial tests whether a shot of your own concentrated platelets (PRP) into the knee improves healing after a recent ACL injury. It's for people with mild to moderate ACL tears and no major other knee damage.
DhakaAges 18–50 - NCT07362355RecruitingPhase 2
New gout pill combined with febuxostat for high uric acid
This trial tests an experimental tablet (SHR4640) added to the standard gout medicine febuxostat (40 mg daily) for people whose uric acid remains too high despite febuxostat alone. The goal is to see if the combination lowers uric acid more effectively and safely.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06972914Enrolling by invitation
Brace wearing time after ACL surgery recovery study
This trial tests how long patients should wear a brace after anterior cruciate ligament (ACL) reconstruction surgery. It aims to find the best duration for faster short-term recovery.
Chongli, HebeiAges 18 years+
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,841 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,937 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.