Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,941 recruiting studies in this area right now.
By phase
- Not applicable9,343
- Phase 2764
- Phase 1557
- Phase 3513
- Phase 4339
- Phase 1/Phase 2300
- Phase 2/Phase 3125
Top conditions
- Stroke796
- Parkinson Disease395
- Alzheimer Disease338
- Multiple Sclerosis329
- Dementia226
- Epilepsy193
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke139
- Sarcopenia135
- Mild Cognitive Impairment127
- Cerebral Palsy119
- Pain Management114
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California659
- Massachusetts305
- New York294
- Florida271
- Texas266
- Maryland248
- Alabama207
- Arizona207
- Illinois181
- Pennsylvania176
Recruiting studies11,941 total
- NCT07542314RecruitingPhase 4
Gene therapy for Duchenne muscular dystrophy
This study is checking how safe and effective ELEVIDYS, a gene therapy for Duchenne muscular dystrophy, is when used in everyday clinics. It will help doctors understand more about the treatment's real-world effects and provide care for those who receive it.
Houston, TexasAges 4 years+ - NCT07536386Recruiting
Robotic Exoskeleton Walking Aid for Spinal Cord Injury
This study tests a self-balancing robotic exoskeleton device designed to help people with spinal cord injuries stand and walk. Researchers will assess whether the device improves mobility and quality of life over nine visits to a research center.
ParisAges 18 years+ - NCT07540364RecruitingPhase 3
Testing Samelisant for Narcolepsy Daytime Sleepiness
This study tests whether a new medication called samelisant can reduce extreme daytime sleepiness and sudden muscle weakness (cataplexy) in people with narcolepsy. If it works, it could offer a new treatment option for managing this sleep disorder.
Columbia, South CarolinaAges 18 years+ - NCT07537075Enrolling by invitationPhase 2/Phase 3
Continuing SKY-0515 treatment for Huntington's disease
This is a follow-up study for people with Huntington's disease who already completed an earlier SKY-0515 trial and tolerated it well. Researchers want to see how safe and effective the drug continues to be with longer-term use.
New Lambton Heights, New South WalesAges 25 years+ - NCT07540897RecruitingPhase 3
Testing ALKS 2680 for narcolepsy type 1
This study tests whether a new medication called ALKS 2680 can help people with narcolepsy type 1 stay more awake and alert during the day. Narcolepsy type 1 is a neurological condition where people fall asleep unexpectedly and may experience sudden muscle weakness.
Brandon, FloridaAges 18–70 - NCT07540572RecruitingPhase 1
Testing IDE574 safety and effectiveness in advanced solid tumors
This early-stage trial tests a new drug called IDE574 to see if it is safe and effective in treating advanced cancers that have spread or stopped responding to standard treatments. The trial focuses mainly on hormone-receptor positive breast cancer, but also includes lung, prostate, and colorectal cancers.
Plantation, FloridaAges 18–99 - NCT07539389Recruiting
Robot-Assisted Walking Training for Children With Cerebral Palsy
This study tests whether a robotic device called Bambini Kids can safely help children with cerebral palsy improve their walking and movement. The robot assists with gait training—guided walking practice—to see if it helps strengthen muscles and improve mobility.
Songpa, SeoulAges 2–10 - NCT07540221RecruitingPhase 3
Comparing two immune therapy infusions for nerve damage
This study tests whether a new immune therapy called XEMBIFY works as well as a standard treatment (Gamunex-C) for CIDP, a condition where the immune system damages nerves and causes weakness. Both are given as infusions under the skin every three weeks.
Rancho Mirage, CaliforniaAges 18 years+ - NCT07541404Recruiting
NeoCast embolization for subdural hematoma treatment
This trial tests a newer way to treat subdural hematoma—a bleeding problem inside the brain. After surgery to drain the blood, you'll receive an additional minimally invasive procedure (middle meningeal artery embolization) using a new device called NeoCast to help prevent the bleeding from coming back.
New Haven, ConnecticutAges 18–90 - NCT06674980Recruiting
Testing placenta-based wound treatment for diabetic and venous leg ulcers
This trial tests if adding a special placenta-based wound covering to standard care helps heal diabetic foot ulcers and venous leg ulcers faster. It's for people with wounds that haven't healed after standard treatment for at least 4 weeks.
Metairie, LouisianaAges 18 years+ - NCT06737055Recruiting
Sleep help for new and expectant parents
This study tests a sleep program for pregnant women and new moms. It uses specially trained helpers to teach better sleep habits, which may improve your rest and well-being.
Providence, Rhode IslandAges 18–99 - NCT06748235Recruiting
Hand strength training for children with cerebral palsy
This study tests a special, intensive hand and arm strength training program for children with cerebral palsy. It aims to see if this training improves how they use their upper limbs in daily activities.
Lahore, Punjab ProvinceAges 6–12 - NCT06735768Recruiting
Daily magnetic brain stimulation to prevent migraines
This study tests a type of magnetic brain stimulation (repetitive TMS) given daily at home to prevent migraines. It may be an option if your migraine medications aren't enough or you want a non-drug treatment.
Vienna, State of ViennaAges 18–65 - NCT07535593RecruitingPhase 2/Phase 3
Electrical Acupoint Stimulation for Consciousness Disorders
This trial tests a non-invasive treatment called transcutaneous electrical acupoint stimulation (TEAS) to help people recover consciousness after severe brain injury. The treatment uses mild electrical pulses on specific points on the hands and may help improve awareness and responsiveness.
Xi'an, ShaanxiAges 18–80 - NCT07537426Recruiting
Acupuncture for Dry Eyes After Facial Paralysis
This trial tests whether tiny acupuncture needles placed under the skin can help relieve dry eyes and other eye discomfort that develops after long-lasting facial paralysis. The goal is to see if this treatment can improve symptoms when standard care hasn't worked well enough.
Hangzhou, ZhejiangAges 18–65 - NCT07536542Recruiting
Dual-Task Training for Hand and Arm Function in Parkinson's
This study tests whether doing hand and arm exercises while performing a second task (like counting or listening) can improve movement and strength in people with Parkinson's disease. The goal is to help you move more smoothly and regain function in your hands and arms.
AnkaraAges 40–65 - NCT07536503Recruiting
How Sleep Quality Affects Thinking and Function in MS
This study looks at whether better sleep helps people with multiple sclerosis (MS) think more clearly and stay more physically active. Researchers will measure your sleep quality and test your memory and everyday abilities to see if they're connected.
Ankara, AnkaraAges 18–65 - NCT07539441RecruitingPhase 1/Phase 2
Mirdametinib for brain and nervous system tumors
This trial tests a drug called mirdametinib for people with specific types of brain tumors or neurohistiocytosis (a rare condition affecting the nervous system). The drug targets mutations that cause these conditions to grow.
Basking Ridge, New JerseyAges 18 years+ - NCT07536022Recruiting
At-Home Ear Stimulation for Walking and Balance in Parkinson's
This study tests a small device worn on your ear (called taVNS) that sends mild electrical signals to help improve walking and balance problems in Parkinson's disease. You'll use it at home, and researchers will track whether it helps you move better.
Charleston, South CarolinaAges 40–85 - NCT07542756RecruitingPhase 4
Testing Common Sleep Medications for Insomnia
This study compares how well different over-the-counter and prescription sleep medications work for insomnia. Researchers will guide you through trying medications one at a time to find what works best for your sleep problems.
Philadelphia, PennsylvaniaAges 18–80 - NCT07540117Recruiting
Social Prescribing to Improve Health in Older Adults
This study tests whether connecting older adults with community activities and exercise programs (like mindfulness and walking) can improve their overall health and quality of life. You'll participate in guided activities designed to keep you active and engaged in your community.
Zhunan, MiaoliAges 55 years+ - NCT07539792RecruitingPhase 2
New Skull Support Plates for Pituitary Tumor Surgery
This study tests a new type of absorbable (dissolvable) support plate used during minimally invasive surgery to remove tumors in the pituitary gland area. The plate helps support the surgical site as it heals. Researchers want to see if this new plate works safely and effectively compared to standard approaches.
Foshan, GuangdongAges 1–80 - NCT07541222Recruiting
Blood pressure medications and surgery recovery outcomes
This study looks at how blood pressure medications affect low blood pressure episodes that happen during and after heart surgery. Researchers want to understand if the number of blood pressure drugs you take before surgery changes how your body handles blood pressure during the operation.
KonyaAges 40 years+ - NCT07539740Recruiting
Brain Stimulation to Help Improve Consciousness After Brain Injury
This study tests whether a non-invasive brain stimulation technique called transcranial theta-burst stimulation (tTIs) can help patients recover consciousness after severe brain injury. The treatment aims to improve responsiveness in people in vegetative states or minimally conscious states.
Guangzhou, GuangdongAges 18–70
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,941 recruiting neurology studies from the U.S. registry right now, out of 18,432 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.