Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,425 recruiting studies in this area right now.
By phase
- Not applicable9,762
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York292
- Florida275
- Texas267
- Maryland245
- Arizona213
- Alabama211
- Illinois189
- Pennsylvania178
Recruiting studies12,423 total
- NCT04707105Recruiting
Study of brain bleeding in hospitalized adults
This study follows adults who are hospitalized after a type of brain bleed called primary intracerebral hemorrhage. It mainly tracks what happens after the bleeding to help doctors understand outcomes and care needs.
Hangzhou, ZhejiangAges 18 years+ - NCT04707794Recruiting
Preventing confusion after non-heart surgery in older adults
This study looks at how often older adults develop sudden confusion (delirium) after non-heart operations under general anesthesia. It may help doctors better predict who is at risk and improve care after surgery.
New Delhi, National Capital Territory of DelhiAges 65 years+ - NCT04707976Recruiting
Smart anal irrigation vs standard care for bowel issues in MS
This study compares a smart device for transanal irrigation with regular bowel care in people with multiple sclerosis (MS) who have ongoing bowel problems. It aims to see if the smart irrigation approach improves bowel control and reduces symptoms.
AarhusAges 18 years+ - NCT04708613Recruiting
Brain testing study for former football players and controls
This study looks at how the brain and thinking may be affected by playing professional football, using brain scans and thinking tests. It also compares former players with similar men who did not play organized football beyond high school.
Pittsburgh, PennsylvaniaAges 29–59 - NCT04708431Recruiting
Study of health and wellbeing in people with androgen insensitivity
This study looks at the long-term health and wellbeing of people with androgen insensitivity, a genetic condition that affects how the body responds to androgens (male-type hormones). It may help your care team understand what to watch for over time and improve future guidance for patients and families.
Bethesda, MarylandAges 8–99 - NCT04709900Recruiting
Tests for stable chest pain using heart scans and pressure measurements
This trial studies how well different heart tests (imaging the blood flow and measuring blood pressure in the heart) work for people with stable chest pain. It may help guide safer, more accurate evaluation when you are not having a heart attack.
CopenhagenAges Any age - NCT04708717Recruiting
Testing brain training for people with cochlear implants
This study focuses on people who already use cochlear implants and tests a way to improve how the brain processes sound timing. If you’re an adult cochlear implant user, you may be able to join and help researchers understand what works best for hearing.
Los Angeles, CaliforniaAges 18 years+ - NCT04712812Recruiting
Study of childhood-onset hereditary spastic paraplegia
This study follows people with hereditary spastic paraplegia that started in childhood to better understand how the condition progresses over time. It may help doctors learn what to expect and how to plan care, using genetic information and family history.
Boston, MassachusettsAges Up to 30 years - NCT04712591Recruiting
Testing a recovery approach for people with severe brain injury
This study is testing a recovery strategy for adults who are in intensive care after a severe brain injury and are not able to follow commands. It may help doctors learn better ways to support recovery in this critical situation.
Miami, FloridaAges 18 years+ - NCT04712656Recruiting
CPAP treatment for sleep apnea and blood pressure changes
This study tests whether using CPAP (a breathing machine) for obstructive sleep apnea can improve blood pressure and heartbeat timing. You’ll have blood pressure checked at the start and again after 6 months, along with a sleep evaluation to confirm eligibility.
Columbus, OhioAges 30–75 - NCT04715399Recruiting
Research study collecting data for neurodegenerative diseases
This study collects health information from people with neurodegenerative diseases, some family members, and healthy controls to help researchers better understand these conditions. It may help future diagnosis and research, and participation may include noninvasive checks and other procedures depending on your situation.
Philadelphia, PennsylvaniaAges 18 years+ - NCT04715646RecruitingPhase 3
Brivaracetam study for children with hard-to-control seizures
This trial looks at how safe brivaracetam is and how well it can be used in children and teens with certain types of epilepsy that are not well controlled. It may help families who are dealing with frequent focal seizures despite taking seizure medicines.
Hawthorne, New YorkAges 1 month+ - NCT04715685Recruiting
Mind-body balance program for children with migraine
This trial studies a mind-body balance approach to help reduce symptoms and disability from pediatric migraine. You may join if your child has migraine headaches and can follow study routines, including keeping a headache diary.
Aurora, ColoradoAges 10–17 - NCT04715984Recruiting
Testing brain-circuit targets during DBS surgery in Parkinson’s
This study looks at how brain connections involved in movement may relate to thinking and memory problems in Parkinson’s disease. It happens during a deep brain stimulation (DBS) operation, using tests while the surgeon is placing an electrode.
Nashville, TennesseeAges 40 years+ - NCT04717869Recruiting
Studying frailty support for ICU patients
This trial looks at ways to help “frailty” (low strength and resilience) in people staying in intensive care units. It mainly enrolls adults who expect to be in the ICU for more than 24 hours, and it tries to avoid people whose mobility problems have other causes.
Los Angeles, CaliforniaAges 18 years+ - NCT04717388Recruiting
Study brain and feelings in people with tinnitus
This study looks at how tinnitus affects the brain, thinking, and emotional well-being. It compares people with chronic tinnitus to people without tinnitus (including a group related to a specific type of epilepsy surgery).
ParisAges 18 years+ - NCT04721717Recruiting
Workshop for healing writing after paralysis
This trial tests whether a structured writing workshop can help people living with paralysis and their ALS caregivers. It focuses on communication through words (spoken or written) to support well-being.
Birmingham, AlabamaAges 18 years+ - NCT04722913Recruiting
Link between forward head posture and neck headache
This study looks at whether a specific neck/head posture (forward head position) is related to cervicogenic headaches. It may help researchers understand what posture and neck factors contribute to these headaches.
GizaAges 18–25 - NCT04722939Recruiting
Testing brain function outcomes after ICU kidney failure treatment
This trial studies how treating severe kidney injury in the ICU may affect patients’ brain and thinking function over time. It compares measurements of brain activity and function after starting kidney replacement therapy.
Kingston, OntarioAges 18 years+ - NCT04724941Recruiting
Screening for alpha-synuclein in early Parkinson’s risk
This study looks for changes in a protein called alpha-synuclein in people who may be in the early “prodromal” stage before Parkinson’s symptoms fully appear. It may help researchers find early markers and understand who is more likely to develop Parkinson’s disease.
KielAges 50–99 - NCT04725409Recruiting
Study brain signals during psychiatric evaluations with SEEG
This study looks at brain activity to better understand psychiatric disorders. You may be able to join if you are already having a specific brain-monitoring procedure at Vanderbilt and can complete questionnaires.
Nashville, TennesseeAges 18 years+ - NCT04731246Recruiting
Eye-movement testing in people with early Parkinson’s
This study uses video recordings of your eye movements to learn more about Parkinson’s disease. It may help researchers better tell Parkinson’s apart from other movement conditions and understand how the disease affects the brain early on.
MonacoAges 18 years+ - NCT04730622Recruiting
Studying muscle and bone changes after a hip fracture
This study looks at how bone health and muscle strength (“osteosarcopenia” — loss of both bone and muscle) change after a hip fracture in older adults. It may help doctors understand who is at higher risk and how to better support recovery after hip surgery.
BolognaAges 65 years+ - NCT04732065RecruitingPhase 1
ONC206 for certain brain tumors in children and young adults
This Phase 1 study tests ONC206, a new targeted medicine, for diffuse midline gliomas (DMG) with a specific gene change (H3K27 altered) and for some other recurrent brain/spinal cord cancers. It is designed to find the right dose and see whether it can control or shrink tumors after initial treatment or when the cancer returns.
San Francisco, CaliforniaAges 2–21
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,425 recruiting neurology studies from the U.S. registry right now, out of 19,436 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.