Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,952 recruiting studies in this area right now.
By phase
- Not applicable9,355
- Phase 2761
- Phase 1558
- Phase 3514
- Phase 4339
- Phase 1/Phase 2300
- Phase 2/Phase 3125
Top conditions
- Stroke798
- Parkinson Disease395
- Alzheimer Disease338
- Multiple Sclerosis328
- Dementia226
- Epilepsy193
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke138
- Sarcopenia134
- Mild Cognitive Impairment127
- Cerebral Palsy119
- Pain Management116
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California661
- Massachusetts305
- New York295
- Florida272
- Texas266
- Maryland248
- Alabama207
- Arizona206
- Illinois181
- Pennsylvania177
Recruiting studies11,952 total
- NCT07458568Recruiting
ViBandz study for children with movement problems
This study tests a wearable device called ViBandz that gives gentle vibrations to help children with neurologic conditions move better. It is for children who are already scheduled to receive this type of vibration therapy as part of their regular care at Children's Mercy Hospital.
Kansas City, MissouriAges 6 months–17 years - NCT07454824Recruiting
Aligning medications with what matters most: patient portal trial
This study tests whether a patient portal tool can help older adults with memory problems and their care partners adjust medications to better match their personal goals and values. It is for people who are 65 or older, have mild cognitive impairment or dementia, are taking a medication that may not be ideal for their age, and use the patient portal.
Baltimore, MarylandAges 65 years+ - NCT07461584Recruiting
Memory boost in older adults with optimal dosing
This study tests a safe, non-invasive brain stimulation method to see if it can improve memory in healthy older adults. It uses carefully chosen doses to find the best approach.
Boston, MassachusettsAges 65 years+ - NCT07459803Recruiting
Speech motor skills study for neurotypical speakers and those with stuttering or dyslexia
This study looks at how different people control their speech muscles, comparing neurotypical speakers to adults who stutter or have dyslexia. It could help us understand why some people have trouble producing fluent speech.
Boston, MassachusettsAges 18–50 - NCT07460232RecruitingEarly Phase 1
PET scan for Cushing disease pituitary adenomas
This study uses a special PET scan (FET PET/CT) to help find tiny pituitary tumors causing Cushing disease. The goal is to improve surgery planning so the tumor can be removed successfully.
Rochester, MinnesotaAges 18 years+ - NCT06789783RecruitingPhase 2/Phase 3
Lithium treatment for Cornelia de Lange syndrome
This trial tests whether lithium can help people with Cornelia de Lange syndrome (CdLS) who have a confirmed NIPBL gene mutation. It might improve their daily life and overall well-being.
Milan, MIAges 4 years+ - NCT06519279Recruiting
Freezing of gait study for Parkinson's patients
This study looks at how Parkinson's disease affects freezing of gait (a sudden feeling of being stuck while walking). It may help researchers better understand this symptom and improve future treatments. You may be able to join if you can walk 10 meters without help and don't have a deep brain stimulator.
Tel AvivAges 18 years+ - NCT06753500RecruitingPhase 4
Numbing medicine during gallbladder surgery
This trial tests whether giving a special numbing medicine during gallbladder surgery helps reduce pain. It is for adults having laparoscopic (minimally invasive) gallbladder removal.
Barranquilla, AtlantivoAges 18 years+ - NCT06796972Recruiting
Emotional impact of fetal surgery for spina bifida
This study looks at how parents make decisions about fetal surgery for spina bifida (myelomeningocele) and how they feel afterward. It aims to understand the emotional and psychological effects to better support families.
Paris, ParisAges 18 years+ - NCT06795932Recruiting
Testing a new nerve stimulation device for frozen shoulder
This study tests if a non-invasive device that stimulates nerves can help treat frozen shoulder (adhesive capsulitis). If you are an adult with frozen shoulder and are in generally good health, you may be able to join to see if this device works.
Saguenay, QuebecAges 18 years+ - NCT06796595Recruiting
Nerve recovery program for chronic pelvic nerve pain
This study tests a medical program designed to help nerves heal better after surgery for long-term pelvic or buttock nerve pain. It looks at results one year after a minimally invasive operation to free compressed nerves.
BordeauxAges 18 years+ - NCT06796920Recruiting
Spinal cord stimulation for leg problems in adrenomyeloneuropathy
This trial tests a small device placed near your spinal cord (called epidural spinal cord stimulation) to see if it can help improve leg movement and stiffness in people with adrenomyeloneuropathy (AMN). If you have AMN and trouble walking due to leg stiffness, this study may explore a new option for you.
Beijing, Beijing MunicipalityAges 22–50 - NCT02693223Recruiting
Get With the Guidelines Stroke Registry for people with recent stroke
This study collects health information from people who were recently treated for certain types of stroke or “TIA” (a warning stroke). It helps doctors understand care and improve future treatment, and you may be included if you were treated in the hospital for one of these conditions.
Dallas, TexasAges 18–125 - NCT04507178RecruitingPhase 2
Nadroparine to improve recovery after bleeding in the brain
This study tests whether nadroparine (a blood-thinning medicine) can improve outcomes after a type of brain bleed called subarachnoid hemorrhage. It focuses on people who have had a brain aneurysm treated with a procedure soon after the bleed.
AmsterdamAges 18 years+ - NCT05150795RecruitingEarly Phase 1
Testing pregabalin before surgery versus fentanyl during surgery
This trial compares two medicines used around the time of surgery—pregabalin given by mouth before surgery versus fentanyl given during surgery—to see which better controls pain after the operation. You might join if you’re a generally healthy surgical patient and aren’t using certain related medicines.
CairoAges 21–45 - NCT06156670Recruiting
A study of closing a PFO to prevent strokes
This trial looks at the safety and results of closing a PFO (a small hole in the heart) in people who have had a stroke or embolism with no other clear cause. If you qualify, doctors will close your PFO using a small tube inserted through a blood vessel and then follow your health over time.
MoscowAges 18–70 - NCT06488183Recruiting
Pain relief study for laparoscopic weight loss surgery
This study compares two ways to manage pain after laparoscopic bariatric surgery: one method involves numbing medicine placed near the surgery site, and the other uses an ultrasound-guided injection near the back. It aims to find which option works better for recovery in people with moderate to severe obesity.
AlexandriaAges 20–50 - NCT06396260Recruiting
Brain network study in ALS with emotional outbursts
This study looks at how ALS affects the brain's structure and networks, especially in people who have sudden emotional outbursts (pseudobulbar affect). You will have brain scans (MRI and MEG) and answer questions to help researchers understand these changes.
Aalborg, Northern JutlandAges 18–90 - NCT06799091Recruiting
Nerve stimulation for fibromyalgia relief
This trial tests whether a nerve stimulation technique can help reduce fibromyalgia symptoms. It is open to women with a confirmed diagnosis of fibromyalgia who have had symptoms for at least three months.
GizaAges 20–45 - NCT04140903RecruitingPhase 4
Oral antibiotics after 14 days for bacterial brain abscess
This trial looks at whether continuing treatment for a bacterial brain abscess using partially oral antibiotics works as well as the usual approach. It may help people who have already had 14 days of antibiotic treatment and are stable enough to take medicines by mouth.
AalborgAges 18 years+ - NCT04317677Recruiting
See if bladder pee timing affects infant sleep
This study checks whether changing or timing bladder emptying (pee/voiding) affects how infants sleep. It may help families and clinicians understand sleep trouble in babies after a breathing/safety event, so care can be better targeted.
BronAges 1 month–1 year - NCT06799273Recruiting
Exercise capacity and outlook in cardiac amyloidosis
This study looks at how well people with cardiac amyloidosis can exercise and how that might relate to their long-term health. You'll do a supervised bike or treadmill test while your heart and lungs are monitored.
Milan, ItalyAges 18–100 - NCT03382158Recruiting
Learn about DICER1-related tumors through a patient registry
This registry collects information about people with known or suspected DICER1-related conditions, including certain rare chest and other tumor types. It helps doctors and researchers understand these conditions better and may support future studies.
Minneapolis, MinnesotaAges birth–100 years - NCT07451600Recruiting
TMS for spasticity and balance in multiple sclerosis
This study tests if transcranial magnetic stimulation (TMS) can help reduce muscle stiffness (spasticity) and improve balance in people with multiple sclerosis. TMS uses magnetic pulses to stimulate parts of the brain.
Ankara, YenimahalleAges 18–60
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,952 recruiting neurology studies from the U.S. registry right now, out of 18,491 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.