Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,425 recruiting studies in this area right now.
By phase
- Not applicable9,762
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York292
- Florida275
- Texas267
- Maryland245
- Arizona213
- Alabama211
- Illinois189
- Pennsylvania178
Recruiting studies12,423 total
- NCT05494034Recruiting
Monitoring heart rhythms after stroke to guide care
This study uses a small implantable heart monitor to track heart rhythm in people after an acute ischemic stroke or TIA. It aims to learn how often hidden heart rhythm problems show up, which could help doctors choose better stroke prevention treatments.
AthensAges 40–100 - NCT05495087Recruiting
Breathing low-oxygen air to test brain benefits in mild memory loss
This study tests whether breathing controlled low-oxygen air (through a disposable face mask) can improve brain function in people with mild cognitive impairment (MCI). You’d be randomly assigned to the real treatment or a sham (placebo-like) control, and you’d need multiple lab visits.
Fort Worth, TexasAges 55–79 - NCT05496673Recruiting
Testing and preventing meningitis in rural Northern Uganda
This study helps doctors find meningitis (and rule it out) and improve screening and prevention in rural clinics. You might be included if you come to the clinic with symptoms that could be meningitis, or if you have HIV and are receiving care there.
LiraAges Any age - NCT05498038Recruiting
Exercise program to help military concussion recovery
This trial studies whether a structured exercise “reset” program can improve recovery after concussion in active-duty service members. There are two groups: one soon after a new concussion and one with either lingering symptoms or a more recently recovered concussion.
Fayetteville, North CarolinaAges 18–40 - NCT05497180RecruitingPhase 1
Testing an oral device to reduce snoring and mild sleep apnea
This Phase 1 study tests whether a passive mouth/oral appliance can lessen snoring and mild obstructive sleep apnea. It may help you by improving airflow during sleep without other intensive treatments.
Edmonton, AlbertaAges 18 years+ - NCT05497609Recruiting
Study of tiny muscle changes in children with cerebral palsy
This study follows children with cerebral palsy (and sometimes acquired brain injury) to learn how the muscles look and change over time at a very small, microscopic level. The results may help researchers better understand what’s happening in the muscles and guide future treatments.
StockholmAges 2–18 - NCT05499741Recruiting
Heat-based therapy to improve sleep in adults with Tourette’s
This trial tests a forehead temperature-regulating therapy to help improve insomnia symptoms in adults who have Tourette’s (and significant tics). It may help you sleep better by testing whether changing forehead temperature can improve sleep quality and efficiency.
Los Angeles, CaliforniaAges 18–50 - NCT05500001Recruiting
Family education after a recent psychosis hospital visit
This study follows young people after a recent hospital stay or discharge for psychosis to see how family education affects outcomes. You may benefit from extra support and structured teaching for both you and your family.
Edmonton, AlbertaAges 17–27 - NCT05500170Recruiting
Study of nicotinamide riboside for sleep and thinking
This trial tests whether nicotinamide riboside can improve sleep quality and help with thinking and memory. You may be invited if your sleep is poor and you do not show signs of dementia on a brief mental test.
Buffalo, New YorkAges 65–85 - NCT05500963Recruiting
TENS to reduce fatigue in relapsing-remitting multiple sclerosis
This study tests whether TENS, a non-drug device that delivers mild electrical signals through the skin, can reduce fatigue in people with relapsing-remitting multiple sclerosis (MS). It also includes an exercise-training portion and checks safety and comfort during the program.
Boulder, ColoradoAges 18–65 - NCT05501262Recruiting
Cryoablation vs steroid injection for Morton’s neuroma pain
This trial compares two ways to treat Morton’s neuroma pain: freezing treatment (cryoablation) versus steroid plus lidocaine injections. It may help people who didn’t improve after trying basic shoe inserts or padding, by seeing which approach works better for symptoms.
Portland, OregonAges 18–105 - NCT05502198Recruiting
How muscle loss matters in advanced liver disease
This study looks at how loss of muscle strength or mass (sarcopenia) relates to advanced liver disease. It may help doctors understand which patients are at higher risk and could guide future care choices.
EksjöAges 18 years+ - NCT05503290Recruiting
Music sessions for pregnant people with epilepsy
This trial tests whether a guided music program (called “The Lullaby Project”) can be helpful during pregnancy for people with epilepsy. It focuses on participating in online musical sessions while you’re pregnant.
Toronto, OntarioAges 18 years+ - NCT05504694RecruitingPhase 1/Phase 2
Ofatumumab for AQP4-positive NMOSD with recent relapses
This trial studies ofatumumab to reduce disease activity in adults with AQP4-IgG positive NMOSD who have had recent relapses. It may help lower the chance of new attacks and help prevent worsening disability over time.
Xi'an, ShaanxiAges 18 years+ - NCT05505019Recruiting
Using music to reduce apathy in Parkinson’s disease
This study tests whether music can help reduce apathy (low motivation) in people with Parkinson’s disease. It may help your mood and daily drive by targeting brain and behavior pathways tied to apathy.
Vancouver, British ColumbiaAges 40–85 - NCT05504941Recruiting
Testing a treatment target map in sudden brain bleeding
This study looks at a special scan (DSA, done with contrast dye) to find a likely “target” that doctors can use when treating sudden brain bleeding. It’s meant to help doctors better understand where treatment may be needed soon after symptoms start.
BaselAges 18 years+ - NCT05505188Recruiting
Predicting long-term pain after head and neck radiotherapy
This study looks for ways to predict and improve pain you may have months after radiotherapy for first head and neck cancer. It may help doctors better anticipate pain and support patients during recovery.
CaenAges 18 years+ - NCT05506228Recruiting
Muscle biopsy during surgery study in brain injury conditions
This study looks at how muscles are affected in children and teens with cerebral palsy or an acquired brain injury. Researchers take a small muscle tissue sample during surgery that you were already having for medical reasons, to better understand muscle changes.
StockholmAges 2–18 - NCT05506085Recruiting
Brain stimulator study for voice spasms with tremor
This trial studies a brain stimulation approach for a specific voice disorder that can include tremor. It aims to better understand how well the treatment works and how to use it more effectively while carefully checking safety with awake procedures.
Indianapolis, IndianaAges 18–70 - NCT05508841Recruiting
Study how brain stimulation may work in mild Alzheimer’s
This study looks at how mild to moderate Alzheimer’s affects response to a noninvasive brain stimulation treatment (transcranial direct current stimulation). It may help researchers learn who benefits most and why.
Toronto, OntarioAges 50–90 - NCT05508971Recruiting
Personalized tonsil surgery for sleep apnea in children with Down syndrome
This study tests whether a personalized surgical approach can treat moderate to severe obstructive sleep apnea (OSA) in children with Down syndrome. The goal is to improve breathing during sleep and overall sleep health.
Aurora, ColoradoAges 2–17 - NCT05509387Recruiting
Stronger brain stimulation to improve naming in Alzheimer’s
This trial tests whether a stronger form of gentle brain stimulation (tDCS) can help people with mild to moderate Alzheimer’s improve word-finding (naming). If you qualify, you’ll be assessed before and during the study to see whether the stimulation improves naming ability.
Toronto, OntarioAges 50–90 - NCT05509101Recruiting
Training a device to help control a prosthetic or brace after stroke
This study looks at improving how a device senses and helps control a prosthetic limb or an orthotic brace for people living with stroke effects. It may help you move and use a device more smoothly, but you must meet specific stroke timing and ability requirements.
Salt Lake City, UtahAges 18–70 - NCT05509153RecruitingPhase 2
N-acetylcysteine trial for people at risk of Huntington’s disease
This Phase 2 study tests whether NAC (a supplement-like medicine) can delay symptoms in people who carry the Huntington’s disease gene expansion but do not yet have clear movement symptoms. You may be asked to take NAC and attend regular visits, scans, and blood tests to see if it changes how likely you are to develop Huntington’s disease within the next 10 years.
Westmead, New South WalesAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,425 recruiting neurology studies from the U.S. registry right now, out of 19,436 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.