Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,952 recruiting studies in this area right now.
By phase
- Not applicable9,355
- Phase 2761
- Phase 1558
- Phase 3514
- Phase 4339
- Phase 1/Phase 2300
- Phase 2/Phase 3125
Top conditions
- Stroke798
- Parkinson Disease395
- Alzheimer Disease338
- Multiple Sclerosis328
- Dementia226
- Epilepsy193
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke138
- Sarcopenia134
- Mild Cognitive Impairment127
- Cerebral Palsy119
- Pain Management116
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California661
- Massachusetts305
- New York295
- Florida272
- Texas266
- Maryland248
- Alabama207
- Arizona206
- Illinois181
- Pennsylvania177
Recruiting studies11,952 total
- NCT07351877Recruiting
Vibration therapy for strength and movement in older adults and stroke survivors
This study tests if a precise vibration device can improve muscle function and mobility in older adults with frailty and stroke survivors. It may help reduce knee pain and enhance rehabilitation outcomes.
TaipeiAges 18–95 - NCT07350564Recruiting
Comparing tight vs. usual blood pressure control after stroke clot removal
This trial tests whether keeping blood pressure very tightly controlled after a stroke clot removal (thrombectomy) is better than standard care. It may help people who have had an acute stroke from a large brain artery blockage and still have high blood pressure after the procedure.
Suzhou, JiangsuAges 18 years+ - NCT07347574Recruiting
Early Alzheimer's detection study in Hong Kong communities
This study aims to find early signs of Alzheimer's in the community through blood tests and assessments. It's for people who can think clearly and agree to participate without major health issues.
Hong KongAges 60–75 - NCT07346378Recruiting
Brain stimulation for post-stroke aphasia
This study tests a new type of brain stimulation called temporal interference stimulation to see if it can safely help people recover language abilities after a stroke. It aims to improve communication for people with post-stroke aphasia.
Hefei, AnhuiAges 18–80 - NCT07347067Recruiting
Trigger point injections for chronic migraine
This study tests if injecting medication into specific painful spots in your muscles (called trigger points) can help reduce chronic migraine pain. It may be an option if you've tried other treatments but still have significant pain.
Beijing, Beijing MunicipalityAges 18–65 - NCT07345702Recruiting
Endovascular therapy for large core posterior stroke
This trial tests endovascular therapy (a procedure to remove a clot through a tube in an artery) versus medical management for people with a severe stroke due to a blockage in the back part of the brain (basilar artery) and a large area of brain damage. The goal is to see if the procedure improves outcomes compared to medication alone.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07349706Recruiting
Breathing exercise for dementia risk reduction
This trial tests a simple breathing exercise done for about 5–10 minutes each day for 8 weeks. It aims to see if this exercise can reduce your risk of dementia. If you are between 60 and 80 years old and have at least one risk factor for dementia, this study may be a fit for you.
Tallahassee, FloridaAges 60–80 - NCT07347431Recruiting
AI tool to understand memory clinic experiences
This study uses a computer program to understand how people with memory problems and their carers talk about their experiences. It aims to help doctors better support dementia care.
North ShieldsAges 65 years+ - NCT07348965Recruiting
High-dose furmonertinib for EGFR-mutant lung cancer that spread to the brain lining
This trial tests a new way to give a targeted therapy (furmonertinib) to people with a specific type of lung cancer that has spread to the lining of the brain. It uses a higher, pulsing dose to try to get more medicine into the brain fluid and stop the cancer there.
Guangzhou, GuangdongAges 18–75 - NCT07345715Recruiting
Melatonin vs. dexmedetomidine for preventing agitation after tonsil surgery in children
This study tests whether giving children either oral melatonin or a nebulized sedative (dexmedetomidine) before surgery can reduce confusion and restlessness (emergence agitation) when they wake up from anesthesia. It may help children recover more calmly after adenotonsillectomy.
Tanta, El-GharbiaAges 3–7 - NCT07343856Enrolling by invitation
Long COVID diagnostic test study
This study is testing a new, non-invasive way to diagnose Long COVID using a simple bioelectrical assessment. It might help if you've had COVID-19 and have been dealing with ongoing symptoms for 12 weeks or longer.
TashkentAges 18–75 - NCT07348627RecruitingPhase 3
Opioid-free hip replacement study
This trial tests if using fewer opioids after hip replacement surgery can still control pain well. It uses a specific type of hip replacement called anterior total hip arthroplasty and aims to help patients recover with less reliance on strong pain medicines.
Atlanta, GeorgiaAges 18 years+ - NCT07351006Recruiting
Exercise for menopause symptoms
This study tests whether a supervised exercise program can help relieve menopausal symptoms without using medication. If you are 45-55 and bothered by symptoms like hot flashes, poor sleep, or mood swings, you may be able to join.
KalmarAges 45–55 - NCT07346703Enrolling by invitation
DHA supplement study for multiple sclerosis patients
This trial tests whether taking a DHA supplement (a type of omega-3 fat) can help people with multiple sclerosis. It aims to see if it may improve muscle function or overall well-being.
La Ñora, MurciaAges 18–65 - NCT07345832Recruiting
Volunteer-led lifestyle program for older adults with muscle loss
This study tests a volunteer-led program to improve muscle health in older adults with sarcopenia. It uses a mobile app to guide exercise and nutrition, and aims to see if this approach helps people regain strength.
Hong KongAges 60 years+ - NCT07349173Recruiting
Testing a new way to assess hand and arm awareness
This study explores how people perceive the space around their affected arm or hand after a condition called 'exclusion' (partial loss of awareness or use). It uses virtual reality to test this, which might lead to better therapies.
NancyAges 18 years+ - NCT07346989Recruiting
Brain stimulation to improve function in frail older adults
This study uses a gentle, non-invasive brain stimulation technique (called transcranial direct current stimulation, or tDCS) to see if it can improve physical function and daily activities in older adults who are showing early signs of frailty. You will be asked to do some simple exercises and cognitive tasks while receiving or not receiving the stimulation.
Valencia, ValenciaAges 65–90 - NCT03434548Recruiting
Imaging study for early and late Huntington’s disease changes
This study uses repeat brain scans (including PET and MRI) to track changes in the brain caused by Huntington’s disease over time. It may help researchers understand disease progress and test how well the scans reflect early vs later disease.
London, EnglandAges 21–75 - NCT06864000Recruiting
Genetic study of a brain condition called CAA
This study looks at the genetic causes of cerebral amyloid angiopathy (CAA), a condition where proteins build up in small brain blood vessels. It aims to better understand the disease and may help guide future treatments.
RouenAges 18–99 - NCT02945774Recruiting
Brain imaging study of inflammation in frontotemporal dementia
This study uses brain scans to look for signs of inflammation in people with probable frontotemporal dementia, and in healthy volunteers for comparison. It may help researchers understand what’s happening in the brain and how it changes over time.
London, OntarioAges 30–95 - NCT00801333Recruiting
Create patient-specific stem cells for research
This study uses adult body cells (from participants) to create special lab cells called stem cells for research. It’s mainly about whether cells can be made and studied, not about treating a disease.
JerusalemAges 18 years+ - NCT03535142Recruiting
Fatty liver in people considering bariatric surgery
This study looks at how fatty liver disease may predict future liver health in people with severe weight gain. It compares people who are planning bariatric (weight-loss) surgery with similar people who are not, to better understand who may be at higher risk.
EsbjergAges 18 years+ - NCT05834920Recruiting
Neurofeedback and brain stimulation to improve attention
This trial studies whether training your brain signals (neurofeedback) and sending gentle pulses to the brain (transcranial pulse stimulation) can improve attention. You might be a candidate if you’re an adult with below-threshold sustained attention scores and meet safety and health requirements.
Hong KongAges 20 years+ - NCT06487364Recruiting
How much change in a Parkinson's quality-of-life test matters
This study looks at a short questionnaire (Parkinson's Disease Questionnaire-8) that measures how Parkinson's affects your daily life. The goal is to find out the smallest change in the questionnaire that really matters to patients.
IstanbulAges 40–80
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,952 recruiting neurology studies from the U.S. registry right now, out of 18,491 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.