Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,952 recruiting studies in this area right now.
By phase
- Not applicable9,355
- Phase 2761
- Phase 1558
- Phase 3514
- Phase 4339
- Phase 1/Phase 2300
- Phase 2/Phase 3125
Top conditions
- Stroke798
- Parkinson Disease395
- Alzheimer Disease338
- Multiple Sclerosis328
- Dementia226
- Epilepsy193
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke138
- Sarcopenia134
- Mild Cognitive Impairment127
- Cerebral Palsy119
- Pain Management116
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California661
- Massachusetts305
- New York295
- Florida272
- Texas266
- Maryland248
- Alabama207
- Arizona206
- Illinois181
- Pennsylvania177
Recruiting studies11,952 total
- NCT06857916Recruiting
Cycle and Stroke With Biofeedback for Power Symmetry
This trial studies the effect of biofeedback on power symmetry during cycling in stroke patients with lower extremity hemiparesis.
Salt Lake City, UtahAges 18–70 - NCT06278194Recruiting
Masseter muscle thickness in gasser ganglion radiofrequency treatment
This trial studies how radiofrequency treatment for facial pain affects the thickness of your chewing muscle. It may help improve future treatments.
Istanbul, BaşakşehirAges 40–85 - NCT06664203Recruiting
Nerve block for arm surgery pain relief
This trial tests a special type of nerve block (called variable volume truncal block) for pain relief during arm, elbow, forearm, hand, or wrist surgery. It may help reduce pain and the need for strong pain medicines.
IstanbulAges 18–65 - NCT06490809Recruiting
Understanding meaningful hand function changes in Parkinson's
This study looks at a simple hand-and-arm test (the Box and Block Test) to see how much improvement matters to people with Parkinson's. It helps doctors understand what small changes in hand function are meaningful to you.
IstanbulAges 50–80 - NCT06536764Recruiting
Relaxation exercises for pregnancy back pain
This trial tests whether progressive muscle relaxation exercises can help reduce low back pain and improve sleep quality during pregnancy. It may be helpful if you are in your second or third trimester, have uncomplicated pregnancy, and are experiencing moderate to severe back pain and poor sleep.
Mirpur, Azad Jammu & KashmirAges 20–40 - NCT06859502Recruiting
National database for cerebrovascular disease research
This study creates a national database of people with cerebrovascular diseases (conditions affecting blood flow in the brain, like stroke or aneurysm). By joining, you help researchers better understand and improve care for these conditions.
Florence, FIAges Any age - NCT06643000Recruiting
High-dose furmonertinib combo for EGFR lung cancer with brain lining spread
This trial tests a strong dose of furmonertinib (a targeted pill) combined with two other drugs, bevacizumab and pemetrexed, for people with EGFR-mutated non-small cell lung cancer that has spread to the lining of the brain or spinal cord. It aims to see if this combination can better control the cancer and improve symptoms.
Zhengzhou, HenanAges 18 years+ - NCT07334743Recruiting
A study to find biomarkers in ALS using tiny brain particles
This trial collects blood and spinal fluid samples from people being checked for ALS. The goal is to find clues (biomarkers) in tiny particles from nerve cells that could help doctors better understand and diagnose ALS.
ParisAges 18 years+ - NCT07339319Recruiting
Treatment and recovery for mild head injury
This study looks at how people with mild head injuries are treated and recover. It may help doctors improve care for patients who have a mild head injury and get a brain scan.
BolognaAges 18 years+ - NCT07341490Recruiting
Comparing CT scan vs angiogram to confirm brain death
This trial compares two imaging methods—CT angiography and traditional angiogram—to see if one is better at confirming complete loss of brain function (brain death) in people with severe brain injury. It may help doctors diagnose brain death more accurately and quickly.
StockholmAges 18 years+ - NCT07339813Recruiting
Understanding brain changes after stroke with advanced MRI
This study uses ultra-powerful MRI to see how the brain reorganizes after a stroke. It may help explain why some people recover arm movement and guide future therapies.
Gif-sur-Yvette, Île-de-France RegionAges 18–70 - NCT07341464Recruiting
Blended tube feeding for children and adults
This study tests if a blended tube-feeding formula made from real food is easy to tolerate and acceptable for people who already use a gastrostomy tube. It may be a good option if you or your child need extra nutrition through a tube.
NottinghamAges 1 year+ - NCT07334912RecruitingPhase 2
Study of AEF0217 for people with Down syndrome
This study tests if an investigational drug called AEF0217 can help improve thinking and daily living skills in people with Down syndrome. It's for ages 16-32 who have a caregiver to support them throughout the trial.
BordeauxAges 16–32 - NCT07341009Recruiting
Study of time processing skills in Alzheimer's disease
This study uses a brain game to measure how people with Alzheimer's disease process the passage of time. The goal is to better understand this ability, which could lead to new ways to support patients.
CaenAges Any age - NCT07338175RecruitingPhase 3
Testing minocycline for brain bleeding recovery
This trial tests if the antibiotic minocycline can help people recover after a spontaneous brain bleed (intracerebral hemorrhage). It is for patients who have a moderate-sized bleed and are within 48 hours of symptoms starting.
Beijing, Beijing MunicipalityAges 18–80 - NCT07340268Recruiting
Brain stimulation for insomnia
This study tests if a gentle electrical current applied to the head can help improve sleep in people with insomnia. It involves wearing a device during sessions and completing questionnaires about your sleep and mood.
Ch’ang-ch’un, JilinAges 18–75 - NCT07337629Recruiting
Painkiller Before Nose Surgery: Paracetamol vs. Ibuprofen
This study tests whether giving a single dose of paracetamol or ibuprofen before nose surgery can reduce the need for stronger painkillers during and after the procedure. It may help you recover with less opioid pain medicine.
SamsunAges 18 years+ - NCT07341984Recruiting
Exercise study for people with ALS
This study tests whether a personalized exercise program, done 3 to 5 times a week for 30 minutes each, can help people with ALS maintain strength and function. It aims to see if tailored physical therapy is safe and beneficial.
Sankt GallenAges Any age - NCT07342075Recruiting
Registry Study of Small Vessel Disease in the Brain
This study tracks people with cerebral small vessel disease (changes in the brain's tiny blood vessels) to learn more about how the condition progresses. It may be a good fit if you are 50 or older and have had an MRI showing these changes.
Beijing, Beijing MunicipalityAges 50 years+ - NCT07337317Recruiting
Testing stairway designs for people with vision loss
This study compares different stairway designs to see which are easier and safer for people with vision impairment. It will help identify features that make stairs more accessible.
Huntsville, AlabamaAges 65 years+ - NCT07337785RecruitingEarly Phase 1
CAR-T cell therapy for autoimmune diseases
This trial tests a new kind of cell therapy (UCAR-T) that targets CD19 and BCMA proteins on immune cells. It is for people with certain neurological autoimmune diseases like multiple sclerosis, myasthenia gravis, chronic inflammatory demyelinating polyneuropathy, or autoimmune encephalitis who have not responded well to standard treatments.
Wuhan, HubeiAges 18–70 - NCT07335315Recruiting
Ultrasound with contrast for pituitary tumor surgery
This trial is testing a special ultrasound during surgery to see if it can help doctors find pituitary tumors, especially in Cushing's disease. The contrast agent is a tiny bubble that makes the tumor show up better on ultrasound.
Rochester, MinnesotaAges Any age - NCT07336277RecruitingPhase 3
Sleep quality study for hospitalized orthopedic trauma patients
This study tests if a special sleep program can help people with leg or foot injuries sleep better in the hospital. It may show if treatments like zolpidem or melatonin help improve sleep after surgery.
Atlanta, GeorgiaAges 18–65 - NCT07339865Enrolling by invitation
Bladder symptoms study for teens moving to adult care
This study looks at how bladder problems, like frequent urination or leaks, affect teenagers and young adults as they switch from pediatric to adult doctors. The goal is to learn what helps you feel better and manage your health.
Ghent, East-FlandersAges 16–25
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,952 recruiting neurology studies from the U.S. registry right now, out of 18,491 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.