Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,425 recruiting studies in this area right now.
By phase
- Not applicable9,762
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York292
- Florida275
- Texas267
- Maryland245
- Arizona213
- Alabama211
- Illinois189
- Pennsylvania178
Recruiting studies12,423 total
- NCT05510401Recruiting
Safe use study of an at-bed safety mattress system
This study checks whether a special bed-safety device (SÉCURIDRAP® SELFIA®) can be used safely for adults who get confused, move at night, or are at risk of falling out of bed. You may be able to join if you already have a prescription for the device and meet other safety and consent requirements.
BailleulAges 18 years+ - NCT05513833Recruiting
School hearing checks with remote specialty follow-up
This study offers hearing screening through schools in certain rural Kentucky counties and uses telemedicine (video/phone) to connect families with hearing specialists when needed. It may help by catching hearing problems earlier and speeding up referrals.
Lexington, KentuckyAges 3–11 - NCT05514340RecruitingPhase 2
Test drug for brain injury after low oxygen at birth
This Phase 2 study tests whether sovateltide can improve safety and outcomes for babies whose brains may have been injured by low oxygen around birth. It focuses on babies who show signs of moderate to severe injury soon after delivery, and who receive standard supportive care.
Mangalore, KarnatakaAges Any age - NCT05515224Recruiting
Study for adults 65+ with memory concerns
This study looks at ways to help older adults with new or ongoing memory or thinking concerns. You may be able to take part if you’re 65 or older, have cognitive concerns, can complete study visits in English or Spanish, and are able to see and hear well enough for assessments.
Bloomington, IndianaAges 65 years+ - NCT05514899RecruitingPhase 2
Cannabidiol and THC study for gut health and brain inflammation in HIV
This Phase 2 study tests whether cannabidiol (CBD) and tetrahydrocannabinol (THC) change the gut microbiome and brain-related inflammation in people with HIV. It may help researchers understand new ways to reduce inflammation, but you would need strict cannabis and CBD/THC avoidance during the study.
San Diego, CaliforniaAges 21–70 - NCT05515237Recruiting
Therapy to improve arm use after stroke
This study tests a therapy plan that focuses on using your more-affected arm more often after stroke, plus added sensory activities. It may help improve how well you can move and use that arm in daily life.
Birmingham, AlabamaAges 18–89 - NCT05516719Recruiting
Study tracking I2BS in Parkinson’s over time
This study follows people with Parkinson’s to see how “I2BS” changes over time using special brain scans and other tests. It may help researchers better understand Parkinson’s and improve how it’s measured in future trials.
Exeter, DevonAges 25 years+ - NCT05516277Recruiting
Insomnia care study for older adults with PTSD
This study tests a treatment plan for insomnia (trouble sleeping) in older adults who also have post-traumatic stress disorder (PTSD). The goal is to see whether improving sleep also supports heart and metabolic health (such as blood sugar and heart-related measures).
North Hills, CaliforniaAges 50 years+ - NCT05516732Recruiting
Testing serotonin activity in the brain in people with Parkinson’s
This study uses special scans to measure how serotonin is released in parts of the brain involved in movement in Parkinson’s disease. It may help researchers understand disease changes and the role of serotonin systems in movement problems.
Exeter, DevonAges 25–85 - NCT05516667Recruiting
Study of Alzheimer’s patients and their families
This study follows people with Alzheimer’s disease and family members over 2 years. It uses regular questionnaires and medical checkups to better understand needs and health changes for patients and caregivers.
France, MarseilleAges 18 years+ - NCT05518578RecruitingPhase 2
Drug trial for hard-to-control focal epilepsy with brain scar
This Phase 2 trial tests SPN-817 in adults whose seizures are still not well controlled despite trying multiple seizure medicines. It targets people with a specific type of brain finding called focal cortical dysplasia and looks at safety/tolerability and seizure outcomes over several weeks.
Jacksonville, FloridaAges 18–70 - NCT05518305Recruiting
Predicting recurrent stroke risk in people with artery narrowing
This study looks at blood markers and brain/artery scan results to predict who with intracranial artery narrowing is more likely to have another stroke. It may help doctors spot higher-risk people earlier and better target prevention.
Los Angeles, CaliforniaAges 30 years+ - NCT05518565Recruiting
Study muscle changes in people with cerebral palsy
This study looks at how muscles work in the body in people with cerebral palsy or an acquired brain injury. It may help researchers understand muscle structure and changes over time, which could guide future treatments.
StockholmAges 2–18 - NCT05518617Recruiting
Imaging study for inherited Parkinson’s using PET, SPECT, and spinal fluid
This trial tests how well special brain scans (PET/SPECT) and spinal fluid tests can show changes in people with inherited (genetic) Parkinson’s. It may help researchers understand what’s happening in the brain and improve how these conditions are measured.
Exeter, DevonAges 25–80 - NCT05520034Recruiting
Nurse teaching plan to help prevent another stroke
This study tests whether nurse-led education and follow-up can lower the chance of having another stroke. It targets people who recently returned home after a first stroke and their main caregiver.
DhakaAges 18 years+ - NCT05520359Recruiting
Testing spinal stimulation and devices to improve movement
This study tests spinal stimulation and mobility-related devices to see if they can improve how well you move. You would visit a lab, do simple movement tasks, and share feedback about comfort and what you experience.
Seattle, WashingtonAges 4–70 - NCT05520268Recruiting
Music therapy plus digital rehab for dementia symptoms
This study tests whether music therapy and a digital music program can improve symptoms and daily functioning in people living with dementia. It may help support memory, mood, or communication by using music-based activities.
HelsinkiAges 60 years+ - NCT05522647Recruiting
Study of risk behaviors in hospitalized confused or agitated patients
This is a study that observes how often and what kinds of “risk behaviors” happen in neurosurgery patients who are agitated or confused. It aims to better understand these behaviors so care can be improved for people who are unable to move or who seem restless.
Clermont-FerrandAges 18 years+ - NCT05522374Recruiting
Study registry for people with suspected or confirmed NBIA
This trial is a research registry that collects information from people who have suspected or confirmed NBIA (a rare inherited brain movement/nerve condition). It helps researchers learn more about the condition and how it affects people, which may support future studies.
OttawaAges Any age - NCT05523505Recruiting
Noninvasive brain stimulation to improve adult reading understanding
This study tests whether a safe, non-drug brain stimulation approach can help adults better understand what they read. It aims to see if the treatment improves reading comprehension and related thinking skills.
Nashville, TennesseeAges 18–40 - NCT05522972Recruiting
Tests video-game and training therapy for amblyopia
This trial studies whether perceptual learning and video-game style training can improve vision in people with amblyopia (lazy eye). You may be included if you have normal vision or amblyopia, and your eye exam does not show other eye problems that could affect results.
Fort Lauderdale, FloridaAges Any age - NCT05525039Recruiting
Vibration plus supplement trial for weak muscles and nerves
This trial studies whether a vibration treatment combined with an HMB supplement can improve weak muscle quality and reduce early nerve-to-muscle connection problems. It is mainly for older adults who already have signs of low muscle strength or function.
Hong KongAges 60 years+ - NCT05524493Recruiting
Brain scans for migraine, visual snow, or epilepsy symptoms
This study uses a very strong MRI brain scanner to better understand conditions like migraine, visual snow, or epilepsy that don’t fully respond to treatment. You may be able to join if you meet specific diagnosis and safety requirements for the scanner.
ZurichAges 18–65 - NCT05524922Recruiting
Sleep problems in people with memory or nerve diseases
This study looks at how sleep issues are related to neurodegenerative (nerve/memory) diseases. It will use sleep testing to see patterns that may help explain night-time symptoms like confusion or frequent waking.
Fuzhou, FujianAges 30–80
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,425 recruiting neurology studies from the U.S. registry right now, out of 19,436 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.