Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,425 recruiting studies in this area right now.
By phase
- Not applicable9,762
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York292
- Florida275
- Texas267
- Maryland245
- Arizona213
- Alabama211
- Illinois189
- Pennsylvania178
Recruiting studies12,423 total
- NCT05638724Recruiting
Long COVID health registry for people of all ages
This study builds a health registry to learn how long COVID affects children, teens, and adults over time. It may help by improving understanding of symptoms and care, even if it does not test a new drug.
Munich, BavariaAges Any age - NCT05641116Recruiting
Exercise plus education program for long-lasting Lyme-related symptoms
This trial tests whether a combined program of adapted exercise and therapeutic education can improve long-lasting symptoms that are thought to be related to Lyme disease. It may help people who have symptoms for over 6 months and are not very active currently.
Clermont-FerrandAges 18 years+ - NCT05641441Recruiting
Study hearing side effects after targeted treatment for vestibular schwannoma
This study looks at how targeted brain/skull-base treatment for a vestibular schwannoma may affect hearing (ear “ototoxicity,” meaning damage to hearing). It may help doctors better predict and prevent hearing problems in people treated for this tumor.
GenevaAges 18 years+ - NCT05641688RecruitingPhase 3
PET brain scan study for people with terminal illness
This Phase 3 study tests an amyloid/tau PET brain imaging agent (called [18F]PI-2620). It aims to see how well the scan helps with brain pathology findings in people who are expected to have a life expectancy of 1 year or less.
Phoenix, ArizonaAges 50 years+ - NCT05642455RecruitingPhase 1/Phase 2
Study of a new treatment for certain childhood cancers
This Phase 1/2 study tests a new therapy for children and young adults with specific types of cancer that have been treated with chemotherapy before. It may help by targeting cancer features in the tumor and using your immune system in a controlled way.
Palo Alto, CaliforniaAges 2–21 - NCT05644171Recruiting
Epidural spinal stimulation for chronic spinal cord injury recovery
This trial tests whether a stimulating device placed near the spinal cord can help improve movement and rehabilitative function in people with long-term spinal cord injuries. It may help some patients strengthen function, but only if they meet specific injury and health requirements.
SingaporeAges 21 years+ - NCT05644184RecruitingPhase 2
Oral polio vaccine for infants and young children in Bangladesh
This trial tests a new oral polio vaccine given to babies and young children. It aims to see whether the vaccine is safe and helps the body build protection against polio.
DhakaAges birth–4 years - NCT05644522Recruiting
At-home brace study for leg support and walking
This study tests an at-home wearable activity monitor and brace-related walking support for people who already use a knee-ankle-foot brace. It may help researchers understand how brace use and day-to-day movement relate to walking ability.
Chicago, IllinoisAges 18–89 - NCT05644327Recruiting
Exercise program to improve sleep in Parkinson’s disease
This study looks at whether an exercise program can improve sleep problems in people with Parkinson’s disease. It’s mainly for those who already have poor sleep quality while taking stable Parkinson’s medicine.
Laval, QuebecAges 40 years+ - NCT05644314Recruiting
Drug-coated stent for narrowed vertebral arteries
This trial studies whether a drug-coated stent placed in a narrowed vertebral artery can improve outcomes for people with artery narrowing from plaque. It also looks at how safe the stent is, since it requires specific blood-thinning medicines around the procedure.
Guangzhou, GuangdongAges 18 years+ - NCT05645003Recruiting
Brain stimulation therapy for nerve pain after spinal cord injury
This trial tests whether painless magnetic stimulation of the brain (non-surgical) can reduce long-lasting nerve pain after spinal cord injury. It may help people whose spinal cord injury-related pain has been present for at least six months.
AfyonkarahisarAges 20–70 - NCT05645081Recruiting
Blood test study to predict stroke risk after TIA
This trial studies tiny particles in your blood (called extracellular vesicles) to understand and predict stroke risk after a TIA (a temporary stroke-like episode). It may help doctors identify who is at higher risk using blood samples, rather than only symptoms and scans.
Merthyr TydfilAges 18 years+ - NCT05646394Recruiting
Registry for blood-clot prevention plans in arterial antiphospholipid syndrome
This study keeps a registry to follow people with antiphospholipid syndrome (APS) who have had arterial blood clots (like stroke). It collects information about the treatment approach your clinician chooses to see how different antithrombotic regimens may perform and be tolerated.
Buenos Aires, Buenos Aires F.D.Ages 18 years+ - NCT05647044RecruitingPhase 1
Brain stimulation to reduce impulsivity and suicidal thoughts after mild TBI
This early-stage study tests whether a noninvasive brain stimulation treatment (called iTBS) can reduce impulsivity and suicidal thoughts in Veterans who have had a mild traumatic brain injury (mTBI) and recent suicidal thinking. If you qualify, you may be offered a monitored treatment plan and assessments for safety and symptom changes.
Hines, IllinoisAges 22–65 - NCT05647135Recruiting
High-protein tube feeds for multiple trauma ICU patients
This trial studies whether very high protein tube-feeding helps critically ill adults with multiple injuries recover better in the ICU. It compares feeding approaches during the time you need breathing support.
BucharestAges 18 years+ - NCT05649514Recruiting
Studying sleep problems in early Alzheimer’s risk patients
This study looks at sleep problems in people with mild Alzheimer’s disease and whether sleep measurements and questionnaires can help researchers understand early changes. You may be able to join if your diagnosis is mild and you can complete repeated sleep and thinking questionnaires with a family caregiver’s help.
Montpellier, HéraultAges 50–85 - NCT05649800Recruiting
Study brain and blood-vessel changes in older adults after stroke
This study looks at how blood flow in the brain and related brain processes change after stroke, especially when someone also has conditions like dementia, depression, or delirium. It may help researchers understand what drives these problems and how they connect.
Leicester, LeicestershireAges 65 years+ - NCT05649930Recruiting
Power training for tight calf muscles in children with spastic paresis
This trial tests whether a specific exercise program that strengthens leg muscle power can improve calf muscle length and strength in children with spastic paresis (stiffness from the brain or nerves). If it works, it may help children move more easily and build stronger calves.
AmsterdamAges 4–18 - NCT05649670Recruiting
Compare starting stroke clot-busting before vs after hospital
This study tests whether starting clot-busting treatment by the emergency team before hospital arrival works better than starting it after you reach the hospital. It may help doctors improve speed and outcomes after an acute stroke.
GarchesAges 18 years+ - NCT05649904Recruiting
Study for adults needing brain fluid drainage after brain bleeding or infection
This study looks at patients age 18+ who need a procedure to drain brain fluid after certain brain bleeds (like intraventricular or subarachnoid bleeding, or chronic subdural bleeding) or after ventriculitis. It aims to better understand and improve care for people with these serious conditions.
Columbus, OhioAges 18 years+ - NCT05650229RecruitingPhase 2
Study of KL1333 for adult mitochondrial disease fatigue and weakness
This Phase 2 trial studies whether KL1333 improves chronic fatigue and muscle weakness in adults with a confirmed mitochondrial genetic disease. You may be eligible if you have persistent fatigue for at least 3 months and signs of muscle involvement, and can safely follow study requirements.
Orange, CaliforniaAges 18 years+ - NCT05651204Recruiting
Study of brain GABA signals in Dravet syndrome
This study looks at “GABA signals” in the body/brain to learn more about Dravet syndrome and how it may relate to seizures. If you have Dravet syndrome caused by a specific SCN1A gene change, you may be asked to provide genetic test results and help with study visits so researchers can compare biomarker readings.
Fort Worth, TexasAges Up to 18 years - NCT05652101Recruiting
Study of skills and development in hyperekplexia
This study looks at how children and adults with hyperekplexia develop and adapt over time. It may help researchers understand what support or treatment approaches work best for day-to-day development.
BronAges 2 years+ - NCT05651945Recruiting
Cardiac rehab program for people after a stroke
This trial studies a supervised cardiac rehabilitation program for people after they have had a stroke. It may help improve heart-related fitness and recovery safety after stroke, especially for patients who need a tailored rehab approach.
Edison, New JerseyAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,425 recruiting neurology studies from the U.S. registry right now, out of 19,436 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.