Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,975 recruiting studies in this area right now.
By phase
- Not applicable9,368
- Phase 2765
- Phase 1561
- Phase 3516
- Phase 4338
- Phase 1/Phase 2301
- Phase 2/Phase 3126
Top conditions
- Stroke799
- Parkinson Disease395
- Alzheimer Disease339
- Multiple Sclerosis330
- Dementia227
- Epilepsy194
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke140
- Sarcopenia134
- Mild Cognitive Impairment129
- Cerebral Palsy120
- Pain Management116
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital125
- Assistance Publique - Hôpitaux de Paris110
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development91
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University70
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California662
- Massachusetts306
- New York296
- Florida272
- Texas267
- Maryland249
- Alabama206
- Arizona206
- Illinois181
- Pennsylvania177
Recruiting studies11,975 total
- NCT06879821Recruiting
High-Intensity Exercise for Parkinson's: Brain and Body
This trial tests whether a high-intensity functional training program (a mix of strength, balance, and endurance exercises) can improve both physical movement and thinking skills in people with early-stage Parkinson's disease. You may qualify if you are in the early stages, exercise regularly, and can walk independently.
Valencia, ValenciaAges 40–80 - NCT05797857Recruiting
Exercise program for transthyretin heart amyloidosis
This trial studies whether a structured exercise training program is safe and helpful for people with transthyretin (ATTR) cardiac amyloidosis. It may help improve fitness and daily functioning, and it may also compare groups for specific eligibility needs.
Boston, MassachusettsAges 60–90 - NCT05191264Recruiting
Screws plus cement to treat bone metastases
This trial looks at a treatment that uses metal screws along with cement to stabilize and treat weakening spots in bones caused by metastases. It’s meant for people who have already received this type of procedure and want to be included in the study.
Saint-EtienneAges 18 years+ - NCT06774989Recruiting
Drug level monitoring in metastatic melanoma treatment
This trial checks how much of two drugs, encorafenib and binimetinib, remain in your blood while treating advanced melanoma that cannot be removed by surgery. The goal is to learn if drug levels affect how well the treatment works.
Boulogne-BillancourtAges 18 years+ - NCT06591975Recruiting
Upper extremity function and balance in Parkinson's disease
This study looks at how arm and hand function relates to balance and mobility in people with Parkinson's disease. Understanding this link may lead to better therapy approaches.
SivasAges 18–80 - NCT06746922Recruiting
Brain stimulation for fibromyalgia pain
This study tests a type of non-invasive brain stimulation called Intermittent Theta Burst Stimulation (iTBS) to see if it can help reduce pain and improve daily function in people with fibromyalgia. It may offer a new option for managing your pain without medication changes.
Izmir, KarabaglarAges 18–65 - NCT06803784Recruiting
Bioproducts in body fluids for early brain disease detection
This study is looking for proteins in blood and other body fluids that could help detect brain diseases like Parkinson's, Alzheimer's, and ALS early. It aims to improve diagnosis and future treatments.
Pozzilli, ItalyAges 20 years+ - NCT06882122Recruiting
Atogepant for episodic migraine: brain and body effects
This study tests a daily pill called atogepant to see how it affects the brain and body in people with episodic migraine. It may help if you have 8 to 14 migraine days a month and haven't tried CGRP treatments before.
Pavia, PAVIAAges 18–70 - NCT06880978Recruiting
Comparing two stent methods for Y-shaped heart blockages
This study compares two stent-placing techniques for people with a specific type of complex heart blockage at a branch point. It aims to see which method is safer and more effective for opening up the artery.
IstanbulAges 18 years+ - NCT03705715RecruitingPhase 1
Study brain immune-cell activity in different mental and brain conditions
This Phase 1 study looks for patterns (correlates) in how “microglial” brain immune cells become activated across different neuropsychiatric conditions and in healthy volunteers. It uses brain imaging to help researchers understand what might drive symptoms and differences between people.
Houston, TexasAges 18–80 - NCT04280458Recruiting
Intensive movement and thinking rehab for children with severe disabilities
This trial tests an intensive rehabilitation program to improve both movement abilities and daily function in children with severe, long-term disability due to early brain injury. It may help children gain better adaptive skills and independence through structured therapy.
Hyères, VarAges 4–13 - NCT06869746Recruiting
Swiss Spinal Tumor Registry Study
This study is creating a registry (a database) to gather information about people with spinal tumors who are undergoing surgery. By joining, you help doctors better understand these tumors and improve future treatments.
Lucerne, Canton of LucerneAges 18 years+ - NCT05817786Recruiting
Electrical nerve stimulation for persistent arm nerve pain
This trial tests whether stimulating the nerve roots in the shoulder area can reduce long-lasting nerve pain in one arm. It may help people whose arm pain has not improved with standard nerve-pain treatments.
Lyon, FranceAges 1.5 years–80 years - NCT05785546Recruiting
Build a wheelchair seat change prediction score
This study looks at how your wheelchair seating setup changes over time and uses that information to create a prediction score. The goal is to help the clinical team better decide when a seat adjustment might be needed.
GarchesAges 18 years+ - NCT06541691Recruiting
Aspirin for heart disease patients in polluted air
This study tests if different types of aspirin (coated or chewable) and a special schedule can help people with heart or blood vessel disease when they are exposed to air pollution. If you live in Tehran and have stable heart disease, you may be able to join.
Tehran, Tehran ProvinceAges 18 years+ - NCT06619613RecruitingPhase 1
Study of CM383 for early Alzheimer's disease
This trial tests a new drug called CM383 in people with mild cognitive impairment or mild Alzheimer's disease. The goal is to see if it can help slow down memory loss.
HefeiAges 50–85 - NCT06660602Recruiting
Brain function check before and after heart surgery
This study checks how well your brain works before and after heart surgery. It uses safe tests like a CT scan and an EEG to see if surgery affects brain function.
BeijingAges 18–80 - NCT06731647RecruitingPhase 2
Anti-inflammatory drugs for pleurodesis in pneumothorax
This trial tests whether using non-steroidal anti-inflammatory drugs (NSAIDs) during pleurodesis (a procedure to seal the lung lining) helps people with a collapsed lung (pneumothorax). It aims to see if these drugs can improve outcomes.
AmiensAges 18 years+ - NCT06688968Recruiting
Music, thinking, and memory in Parkinson's and Alzheimer's
This study looks at how music engagement affects thinking and memory in people with Parkinson's or Alzheimer's disease. It may help researchers understand how music can support brain health as we age.
Montpellier, HéraultAges 60 years+ - NCT06649500Recruiting
Comparing two balance therapy methods for older adults
This trial tests whether a high-tech treadmill (Walker View) or group therapy works better for improving balance and preventing falls in older adults. It also uses artificial intelligence to predict fall risk early.
Rome, RomeAges 65 years+ - NCT06761989Recruiting
Comparing two ways to control pain after Whipple surgery
This study compares two ways to manage pain after a Whipple procedure: one is a shot of morphine into the fluid around the spine, and the other is a small tube placed under the skin at the surgical cut that delivers pain medicine continuously. The goal is to see which method provides better pain relief and recovery.
Seoul, SeoulAges 19 years+ - NCT07282574RecruitingPhase 2
Study of an add-on drug for progressive multiple sclerosis
This trial tests whether adding a new medication, RO7268489, to the standard treatment ocrelizumab (Ocrevus) can help people with progressive forms of multiple sclerosis (MS) by slowing disability progression. The trial will evaluate the safety and effectiveness of this combination approach.
Camperdown, New South WalesAges 18–60 - NCT07282847RecruitingPhase 1/Phase 2
Gene therapy for adults with Pompe disease
This study tests a one-time gene therapy (AB-1009) for adults with late-onset Pompe disease. It aims to see if the treatment is safe and improves muscle and breathing function.
Phoenix, ArizonaAges 18–65 - NCT07284420RecruitingPhase 2
Testing empasiprubart with efgartigimod for myasthenia gravis
This study adds a new drug called empasiprubart to the existing treatment efgartigimod for people with generalized myasthenia gravis (gMG) who have antibodies against acetylcholine receptors (AChR-Ab) and have only partially responded to efgartigimod. The goal is to see if the combination improves daily living more than efgartigimod alone.
Carlsbad, CaliforniaAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,975 recruiting neurology studies from the U.S. registry right now, out of 18,541 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.