Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,425 recruiting studies in this area right now.
By phase
- Not applicable9,762
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York292
- Florida275
- Texas267
- Maryland245
- Arizona213
- Alabama211
- Illinois189
- Pennsylvania178
Recruiting studies12,423 total
- NCT05755919Recruiting
Brain mapping during epilepsy surgery with special brain electrodes
This study looks at how to map brain function in people having epilepsy surgery by recording brain signals using special electrodes placed on or inside the brain. It may help doctors better understand which brain areas cause seizures.
Detroit, MichiganAges 6 months–21 years - NCT05756257Recruiting
MRI study of blood pressure swings after ischemic stroke
This trial looks at whether changes in blood pressure after an ischemic stroke (a stroke caused by blocked blood flow) are linked to recovery and outcomes. You may be asked to have MRI scans soon after arriving to help researchers understand who is at higher risk and why.
New Haven, ConnecticutAges 18 years+ - NCT05756894Recruiting
Stimulation therapy to improve breathing after spinal cord injury
This trial studies a neurostimulation approach to help breathing problems after a spinal cord injury. You may be able to join if you have a certain type and level of spinal cord injury and breathing weakness, and you can safely attend study visits with caregiver support.
Chicago, IllinoisAges 18–85 - NCT05759065Recruiting
Behavioral insomnia treatment for adults with limited resources
This study tests behavioral (non-medication) treatments to help adults with insomnia who have socioeconomic disadvantages access better care through primary care clinics. You may be asked about sleep symptoms, mental health, substance use, and daily schedule to see if the treatment is safe and likely to help you.
Boston, MassachusettsAges 18 years+ - NCT05757141RecruitingPhase 1/Phase 2
Study of fosigotifator for vanishing white matter disease
This early-phase study tests fosigotifator in people with vanishing white matter disease (VWM). The goal is to see whether the treatment is safe and could affect how the disease works in the body and brain.
Boston, MassachusettsAges 6 months+ - NCT05757505Recruiting
Intracranial stent for narrowed brain arteries after symptoms
This trial studies whether an intracranial stent (a small mesh tube placed inside the brain artery) improves outcomes and safety for people with severe, symptomatic narrowing of brain arteries. It may help if symptoms continue despite antiplatelet medicine or if blood flow to the brain is poor.
Luoyang, HenanAges 18–75 - NCT05760287Recruiting
Study of heart ultrasound findings in cardiac amyloidosis
This study looks at how cardiac amyloidosis shows up on heart imaging, especially ultrasound (echocardiography). It may help doctors better describe and track the condition using your exam and test results.
Roma, RMAges 18 years+ - NCT05758831RecruitingPhase 3
Rituximab vs ocrelizumab for relapsing multiple sclerosis
This trial compares rituximab and ocrelizumab in people with relapsing-remitting multiple sclerosis (MS) to see which medicine better controls MS activity. It may help reduce future relapses and new MRI lesions.
Lyon, BronAges 18–55 - NCT05760846Recruiting
Training hand skills after a recent stroke
This study looks at a therapy that helps people with a recent stroke relearn coordinated hand and arm movements. It compares how well motor skill learning works and may help improve functional use of the affected arm.
Yvoir, NamurAges 18–90 - NCT05760885RecruitingEarly Phase 1
Multisensory training to improve standing balance after stroke
This early-stage study tests a multisensory therapy to help people with ongoing balance problems stand more safely after a stroke. It may help your balance by giving targeted feedback to the foot and ankle while you practice standing.
Charleston, South CarolinaAges 21 years+ - NCT05761392Recruiting
App-guided care plan for long-lasting hard-to-treat pain
This trial tests an app-based system to help manage chronic pain using precise treatment planning, including an implanted pain device. It may help by improving follow-up, adjusting care over time, and aiming to reduce pain when usual treatments didn’t work.
BeijingAges 18 years+ - NCT05761756Recruiting
Study of oxygen side effects in otherwise healthy adults
This study looks at what happens in the body when oxygen levels are too high, to better understand the mechanism of oxygen toxicity. You may be eligible if you are a healthy, non-smoking adult without certain medical conditions.
Durham, North CarolinaAges 18–45 - NCT05762419RecruitingPhase 1
FUS and etoposide treatment for midline brain tumors
This early-phase study tests whether focusing ultrasound (FUS) plus etoposide can help treat children and teens with diffuse midline glioma that affects the brainstem (pons) and/or thalamus, especially with an H3K27M change. Participants must have cancer that is getting worse and be healthy enough to safely receive study treatment.
New York, New YorkAges 4–21 - NCT05762796Recruiting
Brain scan and stimulation study for kids with mild concussion
This study tests whether a brain “stimulation” approach, paired with brain imaging (MRI), can help children who still have symptoms after a mild concussion. There is also a comparison group of children without concussion history.
Buffalo, New YorkAges 10–15 - NCT05763732Recruiting
Testing how brain stimulation affects walking in Parkinson’s
This trial looks at how turning on and using a specific Parkinson’s brain stimulator affects your walking. It may help doctors understand what changes in gait (walking) can happen with this device and settings.
Baltimore, MarylandAges 18–89 - NCT05765643Recruiting
Mobile app support for parents managing children’s symptoms
This study tests a smartphone app meant to help parents manage their child’s symptoms at home. You may be able to join if you’re a parent of a medically complex child and can use the app in Chinese.
Kowloon, KowloonAges 2–18 - NCT05764681Recruiting
Study for long-term pain after surgery
This study is for people who have chronic post-surgical pain and have a planned surgery on a leg or the spine. The goal is to better understand this long-term pain and what may help manage it after surgery.
Wilmington, DelawareAges 5–17 - NCT05765110Recruiting
Tracking speech, movement, and thinking in Parkinson’s disease
This study looks at how people with Parkinson’s disease speak, move, and think to see whether these patterns can act like a “biomarker” (a measurable sign) of the disease. It also involves healthy volunteers to compare results.
PragueAges 30–75 - NCT05765162Recruiting
Research study on safer, more tailored anesthesia
This study looks at safer anesthesia—meaning medicines used during procedures—using a more personalized approach. It may help make anesthesia safer for adults having medical procedures.
Nykøbing FalsterAges 18–100 - NCT05766059Recruiting
Noninvasive brain stimulation to aid stroke or phantom limb pain rehab
This trial tests new, noninvasive brain stimulation techniques to help recovery after stroke weakness or after arm amputation with phantom limb pain. If you fit the type and timing of your condition, the study may help improve pain or hand/arm function without surgery.
Milan, LombardyAges 18–85 - NCT05767151Recruiting
Newly diagnosed Parkinson’s study for early disease
This study looks at people newly diagnosed with Parkinson’s disease, before starting Parkinson’s medicines, to better understand early illness. It may help researchers identify patterns that could guide future treatments.
Changsha, HunanAges 30–75 - NCT05767203Recruiting
Study genetic and blood markers in people with inherited intellectual disability
This study looks at genetic-related and blood/biologic markers in people with an inherited (genetic) intellectual disability. The goal is to better understand these differences and how they might relate to the condition.
ParisAges Any age - NCT05768035RecruitingPhase 1/Phase 2
Testing SMART101 after half-matched stem cell transplant
This trial studies a new immune treatment called SMART101 given after a half-matched (haploidentical) stem cell transplant that uses post-transplant cyclophosphamide to prevent complications. It mainly checks safety, and may also look at how well SMART101 helps people with blood cancers recover after transplant.
MarseilleAges 18 years+ - NCT05767216Recruiting
Study of genetic and epigenetic differences in twin pairs with Down syndrome
This study looks at how genetics and gene-regulation (how genes turn on and off) differ between close family members who have different Down syndrome status. Researchers hope the findings will help explain why Down syndrome outcomes can vary even in very closely related people.
ParisAges 4–11
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,425 recruiting neurology studies from the U.S. registry right now, out of 19,436 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.