Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,975 recruiting studies in this area right now.
By phase
- Not applicable9,368
- Phase 2765
- Phase 1561
- Phase 3516
- Phase 4338
- Phase 1/Phase 2301
- Phase 2/Phase 3126
Top conditions
- Stroke799
- Parkinson Disease395
- Alzheimer Disease339
- Multiple Sclerosis330
- Dementia227
- Epilepsy194
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke140
- Sarcopenia134
- Mild Cognitive Impairment129
- Cerebral Palsy120
- Pain Management116
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital125
- Assistance Publique - Hôpitaux de Paris110
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development91
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University70
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California662
- Massachusetts306
- New York296
- Florida272
- Texas267
- Maryland249
- Alabama206
- Arizona206
- Illinois181
- Pennsylvania177
Recruiting studies11,975 total
- NCT07282574RecruitingPhase 2
Study of an add-on drug for progressive multiple sclerosis
This trial tests whether adding a new medication, RO7268489, to the standard treatment ocrelizumab (Ocrevus) can help people with progressive forms of multiple sclerosis (MS) by slowing disability progression. The trial will evaluate the safety and effectiveness of this combination approach.
Camperdown, New South WalesAges 18–60 - NCT07285018RecruitingPhase 2
Study of a new drug for diabetic nerve pain in legs
This trial tests an investigational drug for people with pain caused by nerve damage from diabetes (diabetic peripheral neuropathy). It may help reduce pain in your lower legs if other treatments haven't worked well.
Birmingham, AlabamaAges 18 years+ - NCT07286292RecruitingPhase 2
Vorasidenib for children with IDH-mutated low-grade glioma
This trial studies an oral drug called vorasidenib for children and teens with a slow-growing brain tumor (Grade 2 astrocytoma or oligodendroglioma) that has an IDH1 or IDH2 mutation. The drug is taken daily and may help keep the tumor from growing, avoiding the need for immediate chemotherapy or radiation.
Los Angeles, CaliforniaAges 12–17 - NCT07284472RecruitingPhase 2/Phase 3
Testing drugs for agitation in Alzheimer's disease
This trial tests two new drugs (EXV-802 and EXV-801) to see if they can safely reduce moderate to severe agitation in people with Alzheimer's dementia. If you or a loved one has Alzheimer's and has been experiencing significant agitation for at least two weeks, this study may be an option.
Murrieta, CaliforniaAges 55–90 - NCT07284797RecruitingPhase 1
Safety study for autoimmune disease and healthy volunteers
This trial is testing an experimental drug for safety in people with certain autoimmune diseases—like myositis, scleroderma, or Sjögren's disease—as well as in healthy volunteers. It aims to find out if the drug is safe enough to study further.
MelbourneAges 18–75 - NCT07284823Recruiting
Cionic sleeve study for walking problems in Parkinson's
This trial tests a wearable sleeve that uses gentle electrical signals to help improve walking in people with Parkinson's disease. It aims to see if the sleeve is safe and easy to use.
Carlsbad, CaliforniaAges 22–75 - NCT07284810Enrolling by invitation
Tracking daily function and quality of life with the Cionic Neural Sleeve
This trial asks new users of the Cionic Neural Sleeve to answer questions about how they move and feel in daily life. It helps understand if the device makes a difference in function and quality of life.
San Francisco, CaliforniaAges 22 years+ - NCT07282028RecruitingPhase 2/Phase 3
Spectacle hearing aid study for adults with mild to moderate hearing loss
This study tests a new hearing aid built into glasses for people who have mild to moderate hearing trouble, especially in noisy places. It aims to see if the glasses help you hear better without needing a traditional hearing aid.
Tel AvivAges 18 years+ - NCT07287163Enrolling by invitationPhase 3
Long-term study of vormatrigine for epilepsy
This trial is for adults with epilepsy who have already taken vormatrigine in a previous study or through a special access program. It aims to collect ongoing safety and effectiveness information.
Miami, FloridaAges 18–85 - NCT07279623Recruiting
Nasal stimulation device for migraine prevention
This trial tests if a gentle nasal stimulation device can help prevent migraines. It is for adults with frequent migraines (at least 8 days per month).
StockholmAges 18–65 - NCT07287397RecruitingPhase 1/Phase 2
Testing VTx-002 for safety in ALS patients
This trial tests a new drug called VTx-002 to see if it is safe and tolerable for people with ALS. You may be able to join if you have had symptoms for less than 18 months and have a caregiver who can help.
Phoenix, ArizonaAges 18 years+ - NCT07284784RecruitingPhase 2/Phase 3
Buntanetap for Parkinson's disease study
This trial tests an investigational drug called buntanetap in people with Parkinson's disease. It aims to see if the drug can improve symptoms. There are two groups: those who've taken buntanetap before (Cohort 1) and those with a deep brain stimulator (DBS) implant for at least a year (Cohort 2).
Birmingham, AlabamaAges 40–85 - NCT07284342Recruiting
Study on sleep and advanced Parkinson's with foslevodopa/foscarbidopa
This study looks at how a Parkinson's drug delivered under the skin (foslevodopa/foscarbidopa) affects sleep problems in people with advanced Parkinson's. It is a real-world study that follows your usual treatment, no new experimental drug is being tested.
Málaga, AndalusiaAges 18 years+ - NCT07284420RecruitingPhase 2
Testing empasiprubart with efgartigimod for myasthenia gravis
This study adds a new drug called empasiprubart to the existing treatment efgartigimod for people with generalized myasthenia gravis (gMG) who have antibodies against acetylcholine receptors (AChR-Ab) and have only partially responded to efgartigimod. The goal is to see if the combination improves daily living more than efgartigimod alone.
Carlsbad, CaliforniaAges 18 years+ - NCT06853743RecruitingPhase 2
Study of nicotinamide riboside for Huntington's disease
This trial tests if a vitamin B3-like supplement, nicotinamide riboside, can help people with early to mid-stage Huntington's disease. You will be randomly assigned to take the supplement or a placebo to see if it slows the disease.
OsloAges 18–80 - NCT06883708Recruiting
Online program for dementia caregivers in Malaysia
This trial tests an online program called iSupport-Malaysia to help people who care for a family member with dementia. It aims to reduce stress, burden, and symptoms of depression or anxiety.
Petaling Jaya, Kuala LumpurAges 18–100 - NCT06883019Recruiting
Lecanemab for early onset inherited Alzheimer's
This trial tests a medication called lecanemab for people with early onset familial Alzheimer's disease. It aims to see if the drug can help slow cognitive decline in those with confirmed signs of Alzheimer's in their brain.
Beijing, ChinaAges 18–65 - NCT06882954Recruiting
Managing Asymptomatic Carotid Stenosis
This trial studies the best way to treat people who have a high-grade blockage in their carotid artery but no symptoms. It focuses on blockages greater than 80% with signs of unstable plaque to prevent future strokes.
Roma, RMAges 18 years+ - NCT07285226Recruiting
Creatine for muscle loss in older adults
This trial tests whether taking creatine HCl can help older adults with muscle loss (sarcopenia) improve muscle strength. If you are over 60 and have weak grip strength, this study might be for you.
BelgradeAges 60 years+ - NCT07282938Recruiting
Robot hand and electrical stimulation for hand function after stroke
This test combines a soft robotic hand and electrical stimulation to help improve hand movement in people recovering from a stroke. It may benefit stroke survivors who have some ability to extend their fingers and are in the early months of recovery.
Lahore, Punjab ProvinceAges 45–65 - NCT07283289Recruiting
Obstructive sleep apnea in patients with PAD
This study looks at how common obstructive sleep apnea is in people with peripheral artery disease (PAD). Participants will have a sleep test as part of their regular care.
Toulon, VarAges 18 years+ - NCT07280416Recruiting
Sleep changes in first year after cancer diagnosis
This study follows people who are newly diagnosed with cancer to see how their sleep changes during the first year. It looks at whether treatments like chemo or immunotherapy affect insomnia.
Le Puy-en-VelayAges 18–80 - NCT07286435Recruiting
Vibration therapy after botox for stroke spasticity
This trial tests if adding whole-body vibration therapy to botulinum toxin A (Botox) injections can improve muscle stiffness, balance, and walking in stroke survivors. It may help reduce spasticity and make daily activities easier.
Bursa, BursaAges 18–75 - NCT07285837Recruiting
Intensive arm rehab for kids with cerebral palsy
This study tests an intensive rehabilitation program for the upper limb (arm and hand) in children and teens with cerebral palsy. It aims to improve arm function and may help your child gain more control and independence.
Saint-Fargeau-Ponthierry, Île-de-France RegionAges 3–17
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,975 recruiting neurology studies from the U.S. registry right now, out of 18,541 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.