Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,425 recruiting studies in this area right now.
By phase
- Not applicable9,762
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York292
- Florida275
- Texas267
- Maryland245
- Arizona213
- Alabama211
- Illinois189
- Pennsylvania178
Recruiting studies12,423 total
- NCT05979064Recruiting
Belly fat graft for recurrent brain tumor
This study tests if a piece of your own belly fat (omentum) placed in the brain during tumor surgery can help fight recurrent glioblastoma. It is for people who are already scheduled for surgery to remove their brain tumor.
New York, New YorkAges 18 years+ - NCT05980767Recruiting
Electrical stimulation for better recovery after cubital tunnel release
This trial tests a short burst of electrical stimulation during surgery to improve nerve healing and hand function after cubital tunnel release. It may help people with ulnar nerve problems at the elbow recover faster.
Hamilton, OntarioAges 18–80 - NCT05981261Recruiting
Experimental pain study in Parkinson's and healthy adults
This study looks at how people with Parkinson’s, treated either with levodopa or deep brain stimulation (DBS), and healthy volunteers experience pain. The goal is to understand how Parkinson’s treatments affect pain perception.
AarhusAges Any age - NCT05981482Recruiting
Understanding vision problems after a recent stroke
This study looks at how stroke may affect the way you see and make sense of what's around you. It aims to better understand these visual challenges and may lead to better support after a stroke.
AbingdonAges 18 years+ - NCT05981755Recruiting
Breathing rescue to prevent SUDEP in epilepsy
This trial tests a breathing rescue device to prevent SUDEP (sudden unexpected death in epilepsy) in people with hard-to-control focal epilepsy who are staying in the hospital for invasive brain monitoring.
Houston, TexasAges 18 years+ - NCT05981989Recruiting
Spinal cord stimulation to improve arm and hand function after stroke
This trial tests if a device placed near the spinal cord can help improve movement, feeling, and pain after a stroke. It is for people who have had one stroke and have weakness on one side of the body.
Hualien CityAges 20–70 - NCT05982119Recruiting
Assessing muscle disease patients with activity monitors
This study assesses physical activity in people with different muscle diseases (like Duchenne, FSHD, and others) and in healthy volunteers. It helps doctors understand how these conditions affect daily movement and function.
LiègeAges 1–80 - NCT05982158Recruiting
Talking to an Avatar vs. Talk Therapy for Hearing Voices
This trial compares a new therapy where you talk to a computer avatar that represents the voice you hear, with standard cognitive behavioral therapy (CBT) to help reduce the distress from hearing voices. You must have been hearing voices for at least a year, and they should be upsetting or negative.
Hawthorn, VictoriaAges 18 years+ - NCT05982691Recruiting
Asian data collection for CNS germ cell tumors
This trial is creating a consortium to collect data from Asian patients with CNS germ cell tumors. It helps researchers understand these tumors better and may lead to better treatments.
Goyang-si, Gyeonggi-doAges Any age - NCT05983211Recruiting
TMS therapy study for ALS patients
This trial tests whether repetitive TMS (transcranial magnetic stimulation) can help people with ALS. It uses a special type of TMS that is repeated and measured. You would lie comfortably for about an hour while receiving the treatment.
Toronto, OntarioAges 18 years+ - NCT05982925Recruiting
Brain imaging study in multiple sclerosis
This study uses MRI scans to look at how multiple sclerosis affects the outer layer of the brain over time. It aims to learn more about the disease to help improve future treatments.
New York, New YorkAges 18 years+ - NCT05982730Recruiting
Segway training for balance and thinking in Parkinson's
This study tests whether practicing balance on a Segway can improve walking and thinking for people with moderate Parkinson's. You will train on a Segway while getting special sensory cues, and researchers will see if it helps your motor skills and cognitive function.
Dallas, TexasAges 50–85 - NCT05983263Recruiting
Testing capsaicin patch for tailbone pain
This study looks at how well a capsaicin 8% patch (QUTENZA®) works for pain in the tailbone area (coccygodygnia). It reviews past medical records of people who already received this treatment.
NantesAges Any age - NCT05983757Recruiting
Clot retrieval for smaller brain artery strokes
This trial tests if removing clots from smaller arteries in the brain (not the main ones) helps people who had a stroke and can't get standard clot-busting medicine. It compares clot removal to usual care for strokes caused by these medium-sized vessel blockages.
Atlanta, GeorgiaAges 18 years+ - NCT05983809Recruiting
Balance and walking rehab using technology for MS
This trial tests a new type of balance and walking training for people with multiple sclerosis. It uses technology to help improve your stability and gait, which may help you move more safely and confidently.
Roma, RMAges 18–65 - NCT05984524Recruiting
Gamma music therapy for mild Alzheimer's disease
This study tests whether a specially designed music intervention can help people with mild Alzheimer's disease. You listen to music with a gamma frequency beat, which may improve brain function and memory.
Boston, MassachusettsAges 50–95 - NCT05985161RecruitingPhase 2
Selinexor for wilms tumor and other solid tumors
This trial tests a drug called selinexor for children and young adults with certain types of solid tumors (like Wilms tumor, rhabdoid tumors, MPNST, or others with specific genetic changes) that have come back or not responded to standard treatment. Participants take selinexor pills to see if it can shrink or control their cancer.
Los Angeles, CaliforniaAges 1 year+ - NCT05985213Recruiting
Brain blood vessel disease study at Yueyang Hospital
This study follows people with small vessel brain disease to understand how it changes over time. You may join if you've had an MRI showing this type of brain change and are able to take care of yourself daily.
ShanghaiAges 18–80 - NCT05985473Recruiting
AI speech enhancement for hearing aid improvement
This trial tests whether artificial intelligence can improve speech clarity in hearing aids for people with normal hearing or mild hearing loss. It may help if you have trouble understanding speech in noisy environments.
ParisAges 18 years+ - NCT05985486Recruiting
Lifestyle change for brain health in Down syndrome
This study looks at how a healthy lifestyle program can improve brain health in adults with Down syndrome who are overweight or obese. You will attend a medical center three times over a year for tests, and you'll need a caregiver to support you.
Kansas City, KansasAges 18–64 - NCT05986279Recruiting
MINDGAPS: A balance and mental health study for military members
This study tests a program called MINDGAPS to help Veterans and active-duty service members with their balance and mental health. If you are a military member who can stand on your own and have not had a recent head injury, you may be eligible.
San Diego, CaliforniaAges 18 years+ - NCT05986604Recruiting
Improving Sleep and Daily Rhythms for Older Adults
This study tests a treatment that helps improve sleep and daily rhythms, which may also help with memory and moving around. It's for people aged 50+, with low income, who have trouble with mobility and sleep.
Berkeley, CaliforniaAges 50 years+ - NCT05986487Recruiting
Sleep apnea treatment for better blood pressure control
This trial tests whether treating sleep-disordered breathing (like sleep apnea) can help lower blood pressure in people with high blood pressure. You may join if you have high blood pressure and haven't been diagnosed with a sleep disorder before.
LleidaAges 18 years+ - NCT05986643Recruiting
Brain training game to improve balance in Parkinson's
This trial tests a brain-training game designed to improve balance in people with Parkinson's disease. You may be eligible if you have mild to moderate Parkinson's, have had a fall and freezing episodes in the past year, and are not very active.
LeicesterAges Any age
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,425 recruiting neurology studies from the U.S. registry right now, out of 19,436 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.