Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,425 recruiting studies in this area right now.
By phase
- Not applicable9,762
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York292
- Florida275
- Texas267
- Maryland245
- Arizona213
- Alabama211
- Illinois189
- Pennsylvania178
Recruiting studies12,423 total
- NCT05987592Recruiting
Wellness and brain education for migraine relief
This study tests an 8-week online program that combines brain education and wellness skills to help people with migraine. It aims to reduce headache-related disability and improve quality of life.
Cambridge, MassachusettsAges 18 years+ - NCT05987644RecruitingPhase 1/Phase 2
Timing of brain radiation for ALK-positive lung cancer with brain mets
This trial tests whether it is better to delay brain radiation or give it right away in people with ALK-positive lung cancer that has spread to the brain and is causing few or no symptoms. If you are starting alectinib, you may be able to join and help find the best timing for radiation.
Stanford, CaliforniaAges 18 years+ - NCT05988190Recruiting
Learning new words in children with language disorder
This study looks at how children with developmental language disorder learn new words from context. It aims to find better ways to support their language development.
Johnson City, New YorkAges 7–11 - NCT05988710RecruitingPhase 4
Low-dose buprenorphine for pain in opioid-naive adults
This study tests a low-dose form of buprenorphine (a medicine for pain) placed inside the cheek. It is designed for people who have never taken opioids before, to see how well it works for pain and how likely it is to be misused.
Nashville, TennesseeAges 18–65 - NCT05989620Recruiting
Long-term study of muscular dystrophy functions
This study tracks changes in muscle strength and breathing over time in people with certain types of muscular dystrophy. It helps researchers develop better tests to measure how the disease progresses.
Richmond, VirginiaAges 6–50 - NCT05989763Recruiting
Constipation study for people with systemic sclerosis
This study looks at why people with systemic sclerosis (a disease that can affect connective tissues) develop constipation. It will use special tests to measure how well the colon moves waste, and it may help doctors find better treatments.
Houston, TexasAges 18 years+ - NCT05990244Recruiting
MRE scan to measure brain tumor stiffness before surgery
This study uses a special MRI called magnetic resonance elastography (MRE) to measure how stiff a brain tumor (glioma) is and how well it sticks to nearby brain tissue. The goal is to help doctors better prepare for surgery by knowing these details beforehand.
Shenyang, LiaoningAges 18–80 - NCT05990426Recruiting
Alternate day fasting during chemo for gynecologic cancers
This trial tests whether alternating between a fasting day and a normal eating day can help people recovering from gynecologic cancer surgery while they receive chemotherapy. It aims to see if this eating pattern is safe and helpful during treatment.
Chicago, IllinoisAges 18 years+ - NCT05990790RecruitingPhase 4
Comparing anesthetics and their effect on confusion after surgery
This study compares three different anesthesia medicines to see which one might lower the chance of confusion or delirium after major surgery. If you are 65 or older and having a long, planned non-heart surgery, this trial could help determine the safest option for you.
InnsbruckAges 65 years+ - NCT05990881RecruitingPhase 3
Botox injection for thumb arthritis pain
This study tests if injecting Botox into the thumb joint can reduce pain and stiffness from thumb base arthritis when usual treatments like pills and splints haven't helped enough.
Providence, Rhode IslandAges 18 years+ - NCT05990491Recruiting
Pituitary function after recovery from septic shock in ICU survivors
This study checks how well the pituitary gland (a small gland in your brain that controls hormones) works after you recover from a severe infection that caused dangerously low blood pressure (septic shock). It aims to see if the gland was affected during your ICU stay.
Lucknow, Uttar PradeshAges 18–80 - NCT05991713Recruiting
GPS and brain study for healthy volunteers
This study uses a smartphone GPS app and brain scans (fMRI) to understand how daily emotions and movement patterns are connected. It may help researchers learn more about how people's environments affect their feelings.
Coral Gables, FloridaAges 18–50 - NCT05991804Recruiting
Spinal cord stimulation to improve arm function after injury
This trial tests a treatment that uses mild electrical stimulation on the upper spine to help improve arm and hand function after a recent spinal cord injury. It is for people who are in the hospital and have injury levels between C1 and C8.
LondonAges 18 years+ - NCT05991817Recruiting
Sevoflurane Anesthesia and Memory After Gallbladder Surgery
This study is testing how a common type of anesthesia (sevoflurane) affects memory after gallbladder surgery. If you are having this surgery and are between 30 and 50, you may be able to help doctors learn more about memory and anesthesia.
Santiago, RMAges 30–50 - NCT05992532Recruiting
Study of rare enzyme disorders in monoclonal gammopathy or myeloma
This study looks for two rare inherited disorders—Gaucher disease and acid sphingomyelinase deficiency (ASMD)—in people who already have a blood condition like monoclonal gammopathy (abnormal protein) or multiple myeloma. If you have an enlarged spleen or low platelets, you may be eligible to help researchers understand if these rare diseases are more common in this group.
Vitoria-Gasteiz, AlavaAges 18–99 - NCT05992402Recruiting
Brain training program for epilepsy surgery readiness
This study tests a cognitive training program called ReBOOT for adults with epilepsy who are eligible for surgery. The program is done online and aims to improve brain function before surgery.
Cleveland, OhioAges 18–60 - NCT05993091Recruiting
Mirror therapy and augmented reality for stroke recovery
This study tests whether combining mirror therapy with augmented reality (a computer-generated view of your arm) helps improve arm movement and daily function after a stroke. It may be a good fit if you have some arm movement and can walk.
New Taipei CityAges 30–80 - NCT05993364Recruiting
EFA treatment for brain injury recovery
This trial tests a treatment called EFA for people recovering from a brain injury (from trauma or stroke). It aims to help patients who are still in the early stages of recovery and can breathe on their own during the day.
Rovato, BSAges 18 years+ - NCT05993390Recruiting
Reversing muscle relaxants in ICU patients
This trial tests two medicines that help reverse the muscle-relaxing drugs given to patients on breathing tubes in the intensive care unit. The goal is to see which one works better and faster so patients can wake up sooner.
Seoul, Jongno-guAges 19–90 - NCT05993351Recruiting
Concussion assessment using MRI and blood tests
This study uses MRI scans and blood tests to measure brain recovery after a concussion. It will help doctors understand how concussions affect the brain and find better ways to diagnose them.
Hamilton, OntarioAges 9–50 - NCT05993221Recruiting
Understanding arm weakness after stroke
This study looks at the brain changes that happen after a stroke and how they affect arm movement. It uses MRI scans and gentle magnetic pulses to understand your brain better, which may help guide future treatments.
Providence, Rhode IslandAges 18–90 - NCT05993754Recruiting
Preventing confusion after surgery in frail older adults
This study tests whether a special nursing care plan can help prevent confusion after surgery in older adults who are frail. If you are 65 or older, having planned surgery, and generally healthy enough, this trial may be an option.
Santiago, Santiago MetropolitanAges 65 years+ - NCT05995418Recruiting
Cost and health impact study for Alzheimer's in China
This study looks at the financial and health effects of Alzheimer's disease and mild cognitive impairment (aMCI) in China. It aims to understand how the disease affects patients and families over time.
BeijingAges 40–100 - NCT05995600RecruitingPhase 4
Clopidogrel vs warfarin to prevent a second APS stroke
This study compares two types of blood thinners — clopidogrel (an antiplatelet) and warfarin — to prevent another stroke in people with antiphospholipid syndrome (APS). It aims to find which medicine works better for people who have already had a stroke related to APS.
AnyangAges 19 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,425 recruiting neurology studies from the U.S. registry right now, out of 19,436 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.