Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,435 recruiting studies in this area right now.
By phase
- Not applicable9,772
- Phase 2786
- Phase 1573
- Phase 3535
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3123
Top conditions
- Stroke846
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California680
- Massachusetts300
- New York291
- Florida274
- Texas268
- Maryland245
- Arizona214
- Alabama209
- Illinois190
- Pennsylvania177
Recruiting studies12,433 total
- NCT06253871RecruitingPhase 1
Study of IAM1363 for HER2 Cancers
This trial tests a new oral drug called IAM1363 for people with HER2-altered cancers that have stopped responding to previous treatments. The goal is to see if the drug is safe and how well it works against these cancers.
La Jolla, CaliforniaAges 18 years+ - NCT06253962Recruiting
Can carotid artery scans predict heart disease?
This study looks at whether ultrasound scans of the carotid artery (the main artery in your neck) can help predict blockages in the heart arteries. If you are getting both a carotid ultrasound and a heart angiogram, you may be able to join.
ShanghaiAges 14–90 - NCT06254326RecruitingPhase 1
Immune cell therapy for recurrent oligodendroglioma
This trial tests a personalized immune cell therapy for adults with a specific type of brain tumor (oligodendroglioma) that has come back. The treatment uses your own immune cells to target the tumor.
Gainesville, FloridaAges 18–89 - NCT06254469RecruitingPhase 3
PET scan study for memory decline with head injury or Alzheimer's risk
This trial uses a special PET scan tracer to see if it can predict who will get worse over time. It is for people with mild memory or thinking problems that may be linked to past head injuries or early Alzheimer's disease.
Evanston, IllinoisAges 45 years+ - NCT06254534Recruiting
Medications for eye pressure during breathing tube placement
This study tests how four different medications affect pressure inside the skull during the placement of a breathing tube for surgery. The medications are lidocaine, dexmedetomidine, esmolol, and magnesium—all commonly used to calm the body's response to intubation.
IstanbulAges 18–80 - NCT06255210RecruitingPhase 2
Chemotherapy before surgery for olfactory neuroblastoma
This trial tests whether giving chemotherapy before surgery can help treat olfactory neuroblastoma, a rare type of nose cancer. It aims to see how safe and effective this approach is for people with early to advanced tumors that have not spread to other parts of the body.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06255535Recruiting
Brain-guided brain stimulation for autism
This study tests if a type of brain stimulation (rTMS) guided by brain scans can improve thinking and behavior in people with autism who also have intellectual disability. It aims to help with social communication and daily function.
Fuzhou, FujianAges 6–30 - NCT06256354Recruiting
Managing body temperature during cancer surgery to prevent confusion
This trial tests whether carefully managing a patient's body temperature during cancer surgery can reduce the risk of postoperative delirium and improve long-term survival. It is for older adults undergoing major cancer surgery.
Chizhou, AnhuiAges 65 years+ - NCT06257355RecruitingPhase 1
Testing a new eye drop for corneal scars
This trial tests a new eye drop to see if it can safely and effectively reduce corneal scars. It is for people who have a recent corneal injury (within the last month) that resulted in a scar that affects their vision.
Loma Linda, CaliforniaAges 18–80 - NCT06258109Recruiting
Pregnancy and stroke risk after artery dissection
This study looks at women who had a cervical artery dissection (a tear in a neck artery) and later became pregnant. It wants to see if pregnancy raises the risk of another dissection or stroke.
Salt Lake City, UtahAges 18 years+ - NCT06258837Recruiting
Personalized surgery for sleep apnea in children with small tonsils
This study tests a personalized surgical approach for children with moderate to severe obstructive sleep apnea who have small tonsils. The goal is to see if tailored surgery improves their breathing during sleep and overall health.
Ann Arbor, MichiganAges 2–17 - NCT06259006RecruitingPhase 3
Early Dexamethasone for Sydenham's Chorea in Children
This trial tests whether a short course of dexamethasone (a steroid tablet) can help children with Sydenham's chorea (movement tics after a strep infection) recover faster. The goal is to see if early treatment improves symptoms and reduces side effects compared to other treatments.
Darwin, Northern TerritoriesAges 4–17 - NCT06259292Recruiting
HHT patient registry tracking long-term outcomes
This registry collects health information from people with HHT over time to better understand the disease and improve care. Joining does not involve any experimental treatment, but your data will help researchers learn more about HHT.
Birmingham, AlabamaAges Any age - NCT06260072RecruitingPhase 2
Magnesium and Riboflavin for Post-Concussion Headaches
This trial tests if taking magnesium and riboflavin (vitamin B2) can help reduce headaches after a concussion. It is for University of Virginia students who have had a concussion within the past 3 days and can swallow pills.
Charlottesville, VirginiaAges 18–40 - NCT06261034Recruiting
How sex affects blood pressure control
This study looks at how the nervous system controls blood pressure differently in men and women. It may help researchers understand why some heart conditions affect men and women differently.
Rochester, MinnesotaAges 20–70 - NCT06262529Recruiting
Thinking after a Stroke: A Study of Memory and Thinking
This study looks at thinking and memory problems in younger adults (18 to 45) who have had an ischemic stroke. It aims to understand how a stroke affects the brain's ability to think clearly.
CannesAges 18–45 - NCT06262594RecruitingPhase 3
Testing a sleep medicine for epilepsy-related insomnia
This study tests a new sleep medicine called lemborexant for people with epilepsy whose seizures happen during sleep and who also have trouble sleeping. The goal is to see if the medicine can help you sleep better without making your seizures worse.
Durham, North CarolinaAges 18 years+ - NCT06263608Recruiting
Sleep apnea testing and treatment for atrial fibrillation patients
This study tests a new way to check and treat sleep apnea in people with atrial fibrillation (AF). If you have AF and symptoms, you may be able to join and get sleep tracking and treatment that could help both your heart and sleep.
EdegemAges 18 years+ - NCT06263920Recruiting
Study on late-onset epilepsy and its links
This study looks at people who had their first seizure or were diagnosed with epilepsy after age 18, and compares them to people with migraine. The goal is to understand what might be connected to epilepsy that starts later in life.
Preston, LancashireAges 18 years+ - NCT06264297Recruiting
Nerve radiofrequency treatment for chronic leg pain
This trial tests a new type of treatment (high-voltage pulsed radiofrequency) that uses a special needle to deliver energy to the nerve root in your lower back. The goal is to see if it can reduce chronic leg pain caused by a pinched or irritated nerve.
Terrassa, BarcelonaAges 18 years+ - NCT06264258Recruiting
Game-based diabetes education for kids
This study tests a fun video game to help children aged 6–12 with type 1 diabetes learn about managing their condition. It may improve how kids check their blood sugar and take insulin.
Pittsburgh, PennsylvaniaAges 6–12 - NCT06264427Recruiting
Study of metabolism issues in Greenland
This study looks at the genes and physical traits of people in Greenland with type 2 diabetes or severe obesity. It aims to better understand these conditions to improve care.
Nuuk, SermersooqAges 18 years+ - NCT06264531RecruitingPhase 2/Phase 3
Bevacizumab for adults with symptomatic, untreatable brain AVMs
This trial tests a medication called bevacizumab (given as an IV infusion) to see if it can improve symptoms in people with brain arteriovenous malformations (AVMs) that cannot be treated with standard therapies. It is for those whose AVMs cause significant disability.
Paris, Île-de-France RegionAges 18 years+ - NCT06265506Recruiting
Virtual Reward Program for Cutting Back on Heavy Drinking
This study tests a virtual program that rewards you for reducing heavy drinking. You'd use a phone app, check in via Zoom, and get a glimpse into your drinking patterns through a blood test. It might be a good fit if you want to cut back on heavy drinking without going to an in-person clinic.
Spokane, WashingtonAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,435 recruiting neurology studies from the U.S. registry right now, out of 19,491 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.