Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,435 recruiting studies in this area right now.
By phase
- Not applicable9,772
- Phase 2786
- Phase 1573
- Phase 3535
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3123
Top conditions
- Stroke846
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California680
- Massachusetts300
- New York291
- Florida274
- Texas268
- Maryland245
- Arizona214
- Alabama209
- Illinois190
- Pennsylvania177
Recruiting studies12,433 total
- NCT06245694Recruiting
Emergency room study for neurological deficits
This trial uses advanced data analysis to help doctors in the emergency room better predict and treat neurological problems like stroke or brain injury. It aims to improve care for all adults who come to the ER with these issues.
ViennaAges 18–120 - NCT06246526Recruiting
Spinal cord stimulator for chronic pain study
This study tests a new type of spinal cord stimulator (a device that sends gentle electrical pulses to your spine to block pain signals) for people with chronic pain in their back, chest, or arms or legs. The goal is to see how well it works in real-life settings.
Charleston, West VirginiaAges 18 years+ - NCT06246669Recruiting
Exercise and fear after concussion in college athletes
This study looks at whether prescribed exercise can help college athletes feel less afraid of pain after a concussion. It aims to see if exercise helps them recover better.
Charlottesville, VirginiaAges 18–25 - NCT06247085RecruitingPhase 3
A study testing pegtibatinase for classical homocystinuria
This trial tests an injectable drug called pegtibatinase for people with a rare condition called homocystinuria. It aims to lower high levels of homocysteine in the blood compared to a placebo, while you continue your usual treatments.
Phoenix, ArizonaAges 12–65 - NCT06247631Recruiting
Sleep apnea risk before chest surgery
This study uses a simple questionnaire (STOP-Bang) to check if patients having chest surgery might have undiagnosed sleep apnea or face breathing challenges during surgery. It helps doctors plan safer care.
Ankara, KeçiörenAges 18–65 - NCT06247553Recruiting
Walking exercise program for stroke survivors who can't walk
This study aims to develop a walking exercise program for people who have had a stroke and cannot walk on their own. It will test a treadmill-based program to help improve walking ability.
Kansas City, KansasAges 18–80 - NCT06247449Recruiting
MRI screening for brain metastases in aggressive breast cancer
This trial uses an MRI scan to look for early signs of breast cancer spreading to the brain in people with certain aggressive breast cancer types (triple-negative or HER2-positive) that are stage IIb or III. The goal is to find and treat brain metastases earlier, before they cause symptoms.
Toronto, OntarioAges 18 years+ - NCT06248073Recruiting
Online program and task training for Parkinson's disease
This study tests an online program and task-based training to help people with mild Parkinson's disease improve their movement and reaching ability. It is designed for people who can still sit and reach for objects without major tremors or other health problems.
Linkou DistrictAges 45–70 - NCT06248333Recruiting
Deep brain stimulation for focal motor epilepsy
This trial tests whether deep brain stimulation of a small area in the brain can help reduce seizures that start in the motor part of the brain and do not respond to medication. It may be an option for people who cannot have surgery or whose surgery did not help enough.
Beijing, Beijing MunicipalityAges 14–65 - NCT06248723Recruiting
Preventing memory decline in older adults with lifestyle changes
This study tests a personalized program of lifestyle changes (diet, exercise, brain training, etc.) to see if it can prevent memory loss and keep older adults independent. You may qualify if you are 60+, have mild frailty, and have certain risk factors for dementia.
MonzaAges 60 years+ - NCT06248671RecruitingPhase 2
Atorvastatin for preventing migraine attacks
This trial tests whether a daily dose of atorvastatin (a common cholesterol medicine) can prevent migraine attacks in people with episodic migraine. You would keep a headache diary and be randomly assigned to take atorvastatin or a placebo for about 3 months.
BergenAges 18–65 - NCT06249412Recruiting
Positive pressure breathing device for ALS patients
This trial tests whether a mask that helps you breathe out (positive expiratory pressure) combined with a cough-assist machine (in-exsufflator) improves breathing and coughing in people with ALS who have bulbar symptoms like trouble speaking, swallowing, or drooling.
Le Havre, NormandyAges 18–100 - NCT06249438RecruitingPhase 1
CAR-T cell therapy for hard-to-treat autoimmune diseases
This trial tests a new CAR-T cell therapy (C-CAR168) for people with several autoimmune diseases that have not responded to standard treatments. It aims to see if this therapy can control the disease when other medicines have failed.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT06249867RecruitingPhase 2
Darifenacin for ALS: safety and effect
This trial tests whether darifenacin, a drug currently used for bladder control, can safely help people with ALS. It aims to understand how the drug works in the body and if it can slow the disease or relieve symptoms.
Ottawa, OntarioAges 18–85 - NCT06249919RecruitingPhase 1/Phase 2
Study of NS101 for sudden hearing loss
This trial tests an experimental medicine called NS101 for people who have had a sudden, severe hearing loss in one ear that did not get better with standard steroid treatment. The goal is to see if NS101 can help restore hearing better than steroids alone.
Bucheon-siAges 19–70 - NCT06250491Recruiting
Deep rTMS for Nerve Pain or Fibromyalgia
This study is testing a special type of brain stimulation (deep rTMS) for people with long-term nerve pain or fibromyalgia. The goal is to see if it can help reduce pain that hasn't gotten better with usual treatments.
Boulogne-BillancourtAges 18–80 - NCT06250725Recruiting
Sleep help for memory loss and their caregivers
This study tests a sleep improvement program for older adults with memory loss and their live-in caregivers. Both partners have sleep problems, and the program aims to help them both sleep better and feel better.
Atlanta, GeorgiaAges 18 years+ - NCT06251258Recruiting
Reading emotions in faces: insomnia and feelings study
This study looks at how people with and without insomnia recognize emotions on faces. It aims to understand if sleep problems affect emotional understanding.
AngersAges 18–65 - NCT06251778Recruiting
National study of ATTR heart amyloid patients on tafamidis
This study follows patients with a specific type of heart amyloidosis (wild-type ATTR) who are taking or could start the drug tafamidis. It aims to learn more about how the condition and treatment affect people over time.
PaviaAges 18–99 - NCT06252571RecruitingPhase 2
Melatonin and light therapy for idiopathic hypersomnia
This trial tests whether taking melatonin at night and using a bright light therapy device in the morning can improve excessive daytime sleepiness in people with idiopathic hypersomnia. It is a double-blind study, meaning neither you nor the doctors will know if you are getting the real treatment or a placebo.
StrasbourgAges 18–40 - NCT06253000Recruiting
Heat vs. Freezing for the Back of the Heart
This trial tests two ways to treat the back wall of the heart's left chamber in people with stubborn atrial fibrillation. It compares radiofrequency (heat) and cryoablation (freezing) to see which is safer and works better.
MoscowAges 18–80 - NCT06253104Recruiting
Tracking muscle changes in acute heart failure
This study measures how thigh muscles change in people hospitalized with severe heart failure. It aims to understand muscle loss during this condition and how it relates to recovery.
Boston, MassachusettsAges 18–100 - NCT06253754Recruiting
Study of headache after spinal tap
This trial looks at why some people get a headache after a spinal tap and how treatment might help. It may be an option if you are between 20 and 40 and have this kind of headache.
Umeå, Västerbotten CountyAges 20–40 - NCT06253858Recruiting
Ultrasound guidance for brain drain placement in hydrocephalus
This study tests whether using ultrasound (a type of imaging) to guide the placement of a brain drain (ventricular catheter) is safe and effective for patients with newly diagnosed hydrocephalus (fluid on the brain). If you're already scheduled for the procedure, you may be able to join.
Hershey, PennsylvaniaAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,435 recruiting neurology studies from the U.S. registry right now, out of 19,491 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.