Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,462 recruiting studies in this area right now.
By phase
- Not applicable9,797
- Phase 2786
- Phase 1574
- Phase 3538
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3121
Top conditions
- Stroke854
- Parkinson Disease424
- Multiple Sclerosis342
- Alzheimer Disease340
- Dementia226
- Ischemic Stroke199
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia152
- Traumatic Brain Injury152
- Sarcopenia148
- Acute Ischemic Stroke141
- Cerebral Palsy130
- Mild Cognitive Impairment129
- Pain Management114
- Migraine113
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing95
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- Cairo University63
Where studies are running
- California675
- Massachusetts301
- New York292
- Florida277
- Texas267
- Maryland244
- Arizona216
- Alabama211
- Illinois193
- Pennsylvania177
Recruiting studies12,460 total
- NCT07664358Recruiting
Predicting lung injury after traumatic brain injury
This study looks at whether a simple blood test measuring fibrinogen and albumin levels can help predict if someone with a traumatic brain injury will develop a serious lung condition called acute respiratory distress syndrome (ARDS). It may help doctors identify patients who need extra monitoring and care.
Tanta, Gharbia GovernorateAges 18 years+ - NCT06874322Recruiting
Voiceitt app for people with speech challenges
This trial tests the Voiceitt app, which helps people with speech difficulties communicate more clearly. It may be an option if your speech is hard to understand due to a condition like cerebral palsy, stroke, ALS, or Parkinson's disease.
Pittsburgh, PennsylvaniaAges 13 years+ - NCT07566923Enrolling by invitation
Vagus Nerve Stimulation for Teen Burn Recovery
This study tests a non-invasive device placed on the ear that stimulates the vagus nerve (a major nerve that affects stress and healing) to help adolescents recovering from burns feel less anxious, sleep better, and experience less pain and itching. The device is worn on the outside of the ear and may help your body heal.
Istanbul, KartalAges 12–18 - NCT06789445RecruitingPhase 1/Phase 2
Cell therapy for inherited retinal disease (CLARICO)
This study tests a new cell therapy (OpCT-001) for adults with inherited retinal diseases that affect the light-sensing cells. It aims to see if the treatment is safe and possibly helps improve vision.
Los Angeles, CaliforniaAges 18 years+ - NCT07213440Recruiting
Early markers for ALS study
This study looks for early signs of ALS in people with genetic risk, healthy controls, and people with early symptoms. It aims to find markers that could help diagnose ALS sooner.
Tours, FranceAges 18–90 - NCT07108244Enrolling by invitation
Better brain scan for small pituitary tumors in Cushing's disease
This study tests a special type of brain scan (PET-MRI) to better find tiny pituitary tumors causing Cushing's disease. It may help people whose standard MRI didn't show a clear tumor.
Rotterdam, South HollandAges 18 years+ - NCT06857851Recruiting
Deep brain stimulation study for movement in Parkinson's
This study looks at whether adjusting deep brain stimulation (DBS) can improve how you see and move. DBS uses a device implanted in your brain to help control Parkinson's symptoms. This research aims to find better settings for that device to improve your coordination and daily function.
Cleveland, OhioAges Any age - NCT06708143Recruiting
Temporal interference therapy for drug-resistant epilepsy
This study tests a new, non-invasive treatment called 'temporal interference' for people whose epilepsy seizures are not controlled by medication. It aims to reduce seizures by using low-level electrical fields to calm overactive brain cells.
Beijing, Beijing MunicipalityAges 6–60 - NCT06708468Recruiting
Personalized training for rare neuromuscular disorders
This study tests a personalized exercise program for people with rare neuromuscular diseases like FSHD, DM1, or CMT to see if it improves their physical function and quality of life.
BergenAges 18–70 - NCT06708741RecruitingPhase 3
Vitamin D maintenance after surgery
This trial tests whether taking vitamin D supplements after surgery can help maintain healthy vitamin D levels. It may be a good fit if you are between 21 and 65, had surgery, and are willing to take vitamin D and have your levels checked.
Singapore, SingaporeAges 21–65 - NCT06709950Recruiting
Art therapy for movement recovery after stroke
This study tests art therapy (like painting or clay) to help improve movement and emotional well-being after a recent stroke. It is designed for people in the subacute phase (2 weeks to 3 months after their first stroke) who have mild to moderate physical challenges and can actively participate in creative activities.
Jiamusi, HeilongjiangAges 40–75 - NCT06709898Recruiting
Returning to work after a stroke
This study looks at how job accommodations can help people return to work after a stroke. It focuses on those who had a stroke within the last year and have some thinking or emotional symptoms.
Helsinki, UusimaaAges 18–68 - NCT06710301Recruiting
Navigation skills in virtual reality for children with CP
This study uses a virtual reality headset to understand how children with and without cerebral palsy navigate spaces. Results may help design better therapies for spatial skills.
Bosisio Parini, LCAges 8–17 - NCT06710249RecruitingPhase 2
Testing Salovum and SPC Flakes for Brain Tumor Swelling
This trial tests whether two special food products (Salovum and SPC Flakes) can help reduce brain swelling caused by tumors. If you have a brain tumor with swelling and are already on steroids, you may be able to join.
LundAges 18–79 - NCT06710405RecruitingPhase 4
Lidocaine for pain relief after children's chest surgery
This trial tests whether giving lidocaine during surgery can reduce pain and speed up recovery in children under 7 having chest surgery with a camera. If it works, it could mean less pain and a faster return to normal after the operation.
SeoulAges 6 months–7 years - NCT06710574RecruitingPhase 4
Probiotics for sleep problems in Parkinson's disease
This study tests whether taking probiotics can improve REM sleep behavior disorder (RBD) in people with Parkinson's disease. You will receive either a probiotic supplement or a placebo, and researchers will use brain scans to see how it affects your symptoms.
BeijingAges 40–85 - NCT06711003Recruiting
Enhanced circulation therapy for recent stroke recovery
This trial tests whether a non-invasive treatment that boosts blood flow can help people recovering from a stroke. If you had a stroke within the last month and have moderate to moderately severe disability, you may be eligible to participate and potentially improve your recovery.
TaichungAges 20 years+ - NCT06711159Recruiting
Searching for a biomarker of sleepiness in severe sleep apnea
This study looks for a biological marker of severe daytime sleepiness in people with severe obstructive sleep apnea who haven't started breathing machine treatment yet. It may help doctors better understand and treat sleepiness in the future.
Koege, Regional ZealandAges 18 years+ - NCT06711432Recruiting
Blood Pressure Management During Tumor Surgery and Brain Function
This trial compares different blood pressure management strategies during abdominal tumor surgery to see which one better protects cognitive function (thinking, memory, and clarity). It is for patients who have multiple stroke risk factors and are undergoing a lengthy surgery.
Hangzhou, ZhejiangAges 40–85 - NCT06711731Recruiting
Registry for spinal CSF leak and post-dural headache
This registry collects information from people with suspected spinal CSF leak (a condition where fluid leaks from around your spine) or headaches after a spinal procedure. By joining, you help researchers learn more about these conditions and improve future care.
Freiburg im BreisgauAges Any age - NCT06711952Recruiting
German study of a new memory questionnaire
This study tests a new questionnaire designed to help doctors better understand early memory or thinking problems. It takes place at a memory clinic in Munich and is for people who are already coming in for dementia testing.
München, BavariaAges 50 years+ - NCT06712004RecruitingPhase 2
Testing a new stroke drug: different doses for people who cannot get standard care
This trial tests a new medication (bevifibatide) to see which dose works best for people having an ischemic stroke who cannot get standard treatments like clot-busting drugs or a procedure to remove the clot. It aims to improve recovery by stopping clots from getting worse.
Guangzhou, GuangdongAges 18–80 - NCT06712849Recruiting
Brain stimulation for adult lazy eye
This trial tests a gentle, noninvasive brain stimulation technique (called TMS) to see if it can improve vision in adults with lazy eye. It is a noninvasive approach that does not involve surgery or drugs.
Downers Grove, IllinoisAges 18–55 - NCT06712927RecruitingPhase 2
Three-drug immunotherapy for melanoma brain metastases
This trial tests a combination of three immunotherapy drugs (relatlimab, nivolumab, and ipilimumab) for people with melanoma that has spread to the brain. It aims to see if this treatment can shrink brain tumors and improve outcomes.
Palo Alto, CaliforniaAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,462 recruiting neurology studies from the U.S. registry right now, out of 19,649 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.