Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,462 recruiting studies in this area right now.
By phase
- Not applicable9,797
- Phase 2786
- Phase 1574
- Phase 3538
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3121
Top conditions
- Stroke854
- Parkinson Disease424
- Multiple Sclerosis342
- Alzheimer Disease340
- Dementia226
- Ischemic Stroke199
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia152
- Traumatic Brain Injury152
- Sarcopenia148
- Acute Ischemic Stroke141
- Cerebral Palsy130
- Mild Cognitive Impairment129
- Pain Management114
- Migraine113
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing95
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- Cairo University63
Where studies are running
- California675
- Massachusetts301
- New York292
- Florida277
- Texas267
- Maryland244
- Arizona216
- Alabama211
- Illinois193
- Pennsylvania177
Recruiting studies12,460 total
- NCT07661290Recruiting
High-power laser therapy for cervical radiculopathy
This study tests whether high-power laser therapy can help people with cervical radiculopathy (nerve pain from the neck). The laser is applied to the neck to reduce pain and improve function, and the trial will also see if it affects the shape of the discs in the spine.
CairoAges 40–60 - NCT01682668Recruiting
Deep brain stimulation study for Parkinson movement problems
This study looks at how deep brain stimulation (an implanted brain device) affects Parkinson’s symptoms, especially movement problems like freezing, slowness, or involuntary movements. It may help people whose symptoms are not fully controlled by standard Parkinson medicines.
Paris, PARISAges 18–70 - NCT06435312Enrolling by invitationPhase 3
Studying zilucoplan for children with generalized myasthenia gravis
This study gives an injectable medicine called zilucoplan to children who were part of an earlier trial and could benefit from more treatment. It aims to see if zilucoplan is safe and helpful for young patients with generalized myasthenia gravis.
MilanAges 12 years+ - NCT07346014Recruiting
Sleep therapy for college students at risk of suicide
This study tests if improving sleep can help college students who are already getting mental health treatment for suicidal thoughts. You will try light therapy or sleep schedule changes to see if it reduces suicide risk.
Pittsburgh, PennsylvaniaAges 18–25 - NCT07602582RecruitingPhase 3
Donanemab Extension Study for Alzheimer's Disease
This is a follow-up study for people who already completed a previous donanemab trial (AACM). Donanemab is a medication designed to slow cognitive decline in early Alzheimer's disease by targeting amyloid buildup in the brain.
Phoenix, ArizonaAges 55 years+ - NCT07552714Recruiting
Thread Embedding and Ear Acupressure for Sleep Problems
This study tests whether special threads placed under the skin combined with acupressure on the ears can help people with chronic insomnia (long-term sleep trouble). The treatment is based on Traditional Chinese Medicine ideas about balancing energy in the body.
Ho Chi Minh City, CityAges 40–75 - NCT07688863Enrolling by invitation
Comparing breathing muscle training methods for heart failure
This trial compares two different types of breathing muscle training to see which works better for people with heart failure and weak breathing muscles. You may join if you have heart failure with reduced pumping ability and are stable overall.
Viña del Mar, ValparaisoAges 18 years+ - NCT06641271Enrolling by invitation
Vagus nerve stimulation with hand exercises for MS
This study tests if vagus nerve stimulation (a mild electrical pulse on the ear) combined with hand exercises can help repair the protective coating of your nerves and improve hand function in multiple sclerosis.
Aurora, ColoradoAges 18–70 - NCT07525973Enrolling by invitation
Eye Exercises to Help Parkinson's Disease Symptoms
This study tests whether simple eye exercises can help improve symptoms in people with Parkinson's disease. You'll do supervised eye exercises in a clinic to see if they help with movement, balance, or other Parkinson's symptoms.
IsfahanAges 18–80 - NCT06374264Enrolling by invitation
Music-based walking therapy for NMOSD
This trial tests a music-based walking therapy (called MR-C-014) to see if it is safe and well-tolerated for people with NMOSD who have trouble walking. It may help improve your walking pattern and strength.
Atlanta, GeorgiaAges 18–70 - NCT07678086Recruiting
Breathing tube pressure and sore throat in children's appendix surgery
This trial tests whether carefully managing the pressure in the breathing tube during surgery can help prevent a sore throat in children after they have their appendix removed by keyhole surgery. It may help your child have a more comfortable recovery.
Ankara, YenimahalleAges 6–18 - NCT07039435Recruiting
Perceptual adaptation after cochlear implant
This study looks at how people adapt to hearing with a cochlear implant. It's for adults who are getting one implant in one ear while the other ear has normal or near-normal hearing.
New York, New YorkAges 18 years+ - NCT07655817RecruitingPhase 2/Phase 3
Magnesium for reducing confusion after surgery in children
This trial tests if giving magnesium through the mouth works as well as through the vein to prevent confusion or agitation right after surgery in children having their tonsils out. It aims to find a simpler way to help kids wake up calmly.
Tanta, Gharbia GovernorateAges 4–7 - NCT07494890Recruiting
Walking test study for stroke survivors with slow walking
This study looks at how we measure the effort of walking in people who have had a stroke and still walk slowly. It may help understand your walking and guide better treatments.
Cincinnati, OhioAges 30–80 - NCT07100990RecruitingPhase 3
Early plasma exchange for optic neuritis or myelitis
This trial tests if getting plasma exchange early, along with high-dose steroids, helps people with severe optic neuritis or transverse myelitis recover better than waiting to see if steroids alone work. It aims to find out if faster treatment can prevent lasting vision loss or disability.
Scottsdale, ArizonaAges 18 years+ - NCT02071134Recruiting
Registry study for Vercise deep brain stimulation patients
This study keeps a record of people who receive the Vercise deep brain stimulation system. It helps doctors learn how the treatment is used in real-world care and how patients do over time.
Aliso Viejo, CaliforniaAges 18 years+ - NCT07566871Enrolling by invitation
Nerve Stimulation to Help Burn Injury Recovery
This study tests whether gentle electrical stimulation of a nerve in your ear can help reduce anxiety, improve sleep, and ease pain or itching after a burn injury heals. You would wear a small device on your ear for several weeks.
Istanbul, KartalAges 18–65 - NCT06995625RecruitingPhase 1
Stem cell particles for recent stroke recovery
This trial tests whether stem cell-derived extracellular vesicles can help people recover after a moderate to severe stroke. You may join if you had a stroke in the last 5 days and still have arm or leg weakness, even after standard treatments like clot-busting drugs or clot removal.
Suwon, Gyeonggi-doAges 19 years+ - NCT06997198RecruitingPhase 4
Deutetrabenazine for tardive dyskinesia in people with intellectual disabilities
This trial tests whether deutetrabenazine, a medication already used for tardive dyskinesia, can help people who also have intellectual or developmental disabilities. It aims to see if the drug reduces uncontrolled movements safely over 24 weeks.
Cleveland, OhioAges 18–89 - NCT07673770Recruiting
Brain stimulation to improve memory in dementia
This study tests whether a safe, non-invasive brain stimulation technique called TMS (transcranial magnetic stimulation) can help improve memory and thinking in people with dementia. By measuring your brain waves first, researchers hope to tailor the stimulation to your specific needs.
Hamilton, OntarioAges 55 years+ - NCT07451028Recruiting
Mouth training device for swallowing problems after stroke
This trial tests a device that strengthens mouth muscles to help people who have trouble swallowing after their first stroke. It may improve your ability to swallow safely.
Hammel, JutlandAges 18 years+ - NCT07683780Enrolling by invitation
Spinal stimulation and muscle training for cough after spinal cord injury
This study tests a combination of spinal cord stimulation and electrical muscle stimulation to help improve cough strength in people with a recent spinal cord injury. It may help you clear secretions more effectively.
Chicago, IllinoisAges 18–65 - NCT07477613Recruiting
Brain implant for arm recovery after stroke
This trial tests a brain-computer interface (a device implanted in the brain) to help people who have had a stroke regain arm movement. It may help if you have a single stroke that happened 6 to 18 months ago and still have trouble using your arm.
GrenobleAges 18–70 - NCT07037966Recruiting
Portable brain MRI for multiple sclerosis
This study tests a new portable brain MRI to see if it can help diagnose multiple sclerosis. It may be easier to use than regular machines.
ValenciaAges 18–65
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,462 recruiting neurology studies from the U.S. registry right now, out of 19,649 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.