Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,462 recruiting studies in this area right now.
By phase
- Not applicable9,797
- Phase 2786
- Phase 1574
- Phase 3538
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3121
Top conditions
- Stroke854
- Parkinson Disease424
- Multiple Sclerosis342
- Alzheimer Disease340
- Dementia226
- Ischemic Stroke199
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia152
- Traumatic Brain Injury152
- Sarcopenia148
- Acute Ischemic Stroke141
- Cerebral Palsy130
- Mild Cognitive Impairment129
- Pain Management114
- Migraine113
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing95
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- Cairo University63
Where studies are running
- California675
- Massachusetts301
- New York292
- Florida277
- Texas267
- Maryland244
- Arizona216
- Alabama211
- Illinois193
- Pennsylvania177
Recruiting studies12,460 total
- NCT06768580Recruiting
Melatonin or lidocaine to prevent confusion after hip replacement
This trial tests if giving either oral melatonin or lidocaine during surgery can reduce the chance of confusion (delirium) in older adults after total hip replacement. It compares these two approaches to standard care.
Tanta, El-GharbiaAges 65 years+ - NCT06768749Recruiting
Melatonin lotion for better sleep and mood
This trial tests whether using a scented melatonin lotion before bed can improve sleep and reduce anxiety or depression symptoms. It may be a good fit if you have mild sleep problems and some mood symptoms but are not currently taking medication for them.
Redlands, CaliforniaAges 18–21 - NCT06769308Recruiting
Brain wave guided sedation in ICU patients
This study tests a new way to give pain and sedation medicines in the ICU. It uses a special brain wave monitor (EEG) to help doctors adjust your medicines more precisely, aiming to keep you comfortable and safe.
Ferrara, ItalyAges 18–90 - NCT06769373Recruiting
Whirlpool and contrast bath for CRPS after wrist fracture
This study tests whether warm water whirlpool baths or alternating hot and cold water baths (contrast bath) can help reduce pain and improve function in people with Complex Regional Pain Syndrome (CRPS) after a wrist fracture that was treated without surgery.
Afyonkarahisar, AfyonkarahisarAges 18–70 - NCT06769607Recruiting
New auto-CPAP algorithm for sleep apnea
This study tests a new, smarter way for your CPAP machine to automatically adjust air pressure while you sleep. If you have a ResMed AirSense 10 or 11 and have been using it for a few months, you may be eligible.
Bella Vista, New South WalesAges 18 years+ - NCT06769672Recruiting
Walking and thinking training with brain stimulation for stroke recovery
This study tests whether combining dual-task training (walking while doing a thinking task) with a gentle brain stimulation technique called tDCS can improve how stroke survivors move and think. It may help you walk safely while also paying attention to other tasks.
Hong KongAges 50 years+ - NCT06769633RecruitingPhase 2
Study of givinostat in young boys with Duchenne muscular dystrophy
This trial tests an experimental drug called givinostat in boys ages 2 to under 6 years with Duchenne muscular dystrophy (DMD). The study looks at how the drug works in the body and if it is safe, with the goal of finding new treatment options for young children.
BrusselsAges 2–6 - NCT06769659RecruitingPhase 2
Testing NPT 2042 for absence seizures in genetic epilepsy
This trial tests a new medication called NPT 2042 for people with a type of epilepsy that causes brief staring spells (absence seizures). It aims to see if the drug can reduce seizure frequency compared to a placebo (an inactive pill).
Little Rock, ArkansasAges 16–75 - NCT06770218Recruiting
Pelvic taping for stability in Down syndrome
This trial tests whether taping the pelvic area can help children with Down syndrome feel more stable. It may improve their movement and balance.
Lahore, Punjab ProvinceAges 4–10 - NCT06771284Recruiting
Helping young children with behavior challenges
This study looks at understanding and improving problem behavior in young children with developmental delays. If your child is between birth and 5 years old, has a developmental delay, and shows problem behavior, you and your early intervention professional can be coached by researchers to help your child.
Las Vegas, NevadaAges birth–5 years - NCT06772077Recruiting
Testing a walking robot for kids with spinal cord injury
This study tests a wearable robotic exoskeleton called ATLAS 2030 to help children with a spinal cord injury practice standing and walking. The goal is to see if it is safe and easy to use.
ToledoAges 3–14 - NCT06772142RecruitingEarly Phase 1
Testing a new device for knee, arm, or shoulder pain
This study tests a new wearable device that uses mild electrical pulses to treat chronic pain in the knee, arm, or shoulder. It is for people whose pain started after surgery or injury and who have not found enough relief with standard treatments.
Panama City, Provincia de PanamáAges 18–80 - NCT06772220Recruiting
Homocysteine management for Parkinson's patients on levodopa
This trial tests whether controlling homocysteine levels can help people with Parkinson's disease who are taking levodopa. You may qualify if you take at least 300 mg of levodopa per day, are between 40 and 90 years old, and have no major kidney problems or uncontrolled high blood pressure.
Portland, OregonAges 40–90 - NCT06772194Recruiting
Taiwan Recovery After Stroke Study
This study looks at how people recover after a stroke. Researchers will check your thinking, memory, and daily function over a year to learn more about recovery patterns and help design better treatments.
TaipeiAges 18 years+ - NCT06772740Recruiting
Middle meningeal artery embolization for chronic subdural hematoma
This trial tests a procedure called middle meningeal artery embolization, which aims to stop the bleeding and reduce the fluid buildup from a chronic subdural hematoma. It may be an option for patients who have a hematoma at least 10mm thick and one or more risk factors such as older age, blood thinners, diabetes, or certain scan features.
Nishinomiya, HyōgoAges 18 years+ - NCT06773143Recruiting
Esketamine for sleep quality during breast cancer chemo
This trial tests whether a low dose of esketamine can improve sleep quality in women with breast cancer who are receiving neoadjuvant chemotherapy. If you have trouble sleeping during treatment, this study may find a new way to help.
Nanjing, JiangsuAges 18–65 - NCT06773286Recruiting
Stimulation and therapy for hand function after spinal cord injury
This trial is testing a safe method of electrical stimulation through the skin (called transcutaneous stimulation) combined with physical therapy to help people who recently had a cervical spinal cord injury improve hand and arm function. It is designed for people who are still in the hospital rehab setting.
West Orange, New JerseyAges 18–75 - NCT06773364RecruitingPhase 3
Early levetiracetam and head position for stroke
This trial tests if starting a seizure medication called levetiracetam early in the ambulance, along with a specific head position, can help people having a stroke. It is for adults who show clear stroke signs within the last 2 hours and do not have other major health problems.
Suzhou, AnhuiAges 18 years+ - NCT06773988Recruiting
Long-term monitoring of breathing support at home for Duchenne patients
This study follows adults with Duchenne muscular dystrophy who use a breathing machine (non-invasive ventilation or NIV) at home. It aims to track their health over time to improve care.
Leuven, Vlaams-BrabantAges 18 years+ - NCT06774989Recruiting
Drug level monitoring in metastatic melanoma treatment
This trial checks how much of two drugs, encorafenib and binimetinib, remain in your blood while treating advanced melanoma that cannot be removed by surgery. The goal is to learn if drug levels affect how well the treatment works.
Boulogne-BillancourtAges 18 years+ - NCT06774443Recruiting
Testing social thinking in Huntington's disease
This trial uses a hinting task to study how people with Huntington's disease understand indirect requests. It may help researchers learn more about social thinking in this condition.
Groningen, Provincie GroningenAges 18–74 - NCT06775028Recruiting
Integrated care for older adults with atrial fibrillation
This trial is testing a new approach to care for older adults with atrial fibrillation (an irregular heartbeat) who also have other health conditions. It aims to see if a more integrated, team-based care plan helps improve their overall health and quality of life.
HaskovoAges 65 years+ - NCT06775262Recruiting
chronic fatigue in internal medicine patients
This study looks at people with chronic fatigue who saw a doctor but no physical cause was found. It aims to understand their experiences better.
Almere Stad, FlevolandAges 18 years+ - NCT06775535Recruiting
Spinal cord stimulation trial for chronic pain
This trial tests a closed-loop spinal cord stimulator that adjusts stimulation based on nerve signals. It may help people with chronic pain who are already scheduled to try this type of device.
RoeselareAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,462 recruiting neurology studies from the U.S. registry right now, out of 19,649 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.