Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,462 recruiting studies in this area right now.
By phase
- Not applicable9,797
- Phase 2786
- Phase 1574
- Phase 3538
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3121
Top conditions
- Stroke854
- Parkinson Disease424
- Multiple Sclerosis342
- Alzheimer Disease340
- Dementia226
- Ischemic Stroke199
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia152
- Traumatic Brain Injury152
- Sarcopenia148
- Acute Ischemic Stroke141
- Cerebral Palsy130
- Mild Cognitive Impairment129
- Pain Management114
- Migraine113
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing95
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- Cairo University63
Where studies are running
- California675
- Massachusetts301
- New York292
- Florida277
- Texas267
- Maryland244
- Arizona216
- Alabama211
- Illinois193
- Pennsylvania177
Recruiting studies12,460 total
- NCT06763055RecruitingPhase 3
Study of two drugs for spontaneous brain bleed recovery
This trial compares two medicines (deferoxamine and colchicine) to see if they can prevent further brain damage after a spontaneous brain bleed (intracerebral hemorrhage). The goal is to improve recovery by reducing inflammation and iron-related damage.
Sydney, New South WalesAges 18–80 - NCT06763458Recruiting
Balloon angioplasty for minor unstable stroke with brain artery narrowing
This trial tests if balloon angioplasty (opening a narrowed artery with a tiny balloon) can help people who have had a minor stroke and are still having symptoms despite taking blood thinners.
ShenyangAges 18 years+ - NCT06763575Recruiting
Surgical glove compression to prevent nerve damage from paclitaxel
This trial tests if wearing surgical gloves that compress the hands can prevent nerve damage caused by the chemotherapy drug paclitaxel. If you have a solid tumor and are getting paclitaxel every 3 weeks, this might help reduce numbness, tingling, or pain in your hands.
Bangkok, BangkokAges 18 years+ - NCT06763848Recruiting
Blood filtering for NMOSD attacks
This trial tests a blood filtering procedure called Protein A immunoadsorption for people having an acute episode of neuromyelitis optica spectrum disorder (NMOSD). It may help remove harmful antibodies from your blood and reduce symptoms.
Guangzhou, GuangdongAges 18–65 - NCT06764290Recruiting
Brain changes when walking after stroke
This study looks at how the brain changes after a stroke when people walk on different surfaces. It may help understand why walking can be harder and how therapy could improve it.
Nanjing, JiangsuAges 18–70 - NCT06764563Recruiting
Mediterranean diet study for multiple sclerosis quality of life
This trial tests whether following a Mediterranean diet can improve quality of life for people with multiple sclerosis (MS). It aims to find a dietary approach that may help manage symptoms and improve well-being.
Tel Aviv, IsraelAges 18–70 - NCT06764602Recruiting
Kidney health in kids with tuberous sclerosis
This study looks back at medical records to see how many children with tuberous sclerosis complex (TSC) have kidney problems. It may help doctors understand how common kidney issues are in kids with TSC.
BolognaAges Up to 17 years - NCT06764797RecruitingPhase 3
Virtual reality and brain stimulation for arm recovery after stroke
This trial tests whether combining virtual reality mirror therapy with a gentle brain stimulation technique can improve arm and hand movement in people who have had a stroke. It may be an option if you have moderate to severe arm weakness and it has been more than three months since your stroke.
Riyadh, Riyadh RegionAges 18 years+ - NCT06765161RecruitingPhase 3
Efgartigimod for IVIG-dependent myasthenia gravis
This study tests a medication called efgartigimod for people with myasthenia gravis who need regular IVIG treatments. The goal is to see if efgartigimod can help reduce the need for IVIG.
Gatineau, QuebecAges 18–80 - NCT06765499Recruiting
Silkworm pupa powder for nutrition and frailty in motor neuron disease
This trial tests whether silkworm pupa powder can improve nutrition and reduce frailty in people with motor neuron disease (like ALS). It looks for volunteers who are frail, have a confirmed diagnosis, and are willing to provide blood, stool, and urine samples.
Hangzhou, ZhejiangAges 18–80 - NCT06765668RecruitingPhase 4
Study of CREXONT for Parkinson's with wearing-off episodes
This study tests how well CREXONT, an extended-release form of carbidopa-levodopa, controls symptoms in people with Parkinson's who experience predictable 'off' periods when their regular medication wears off. The goal is to see if it can reduce the daily hours of poor mobility.
Phoenix, ArizonaAges 18 years+ - NCT06765642Recruiting
Brain stimulation for hand strength after stroke
This study tests whether a safe, non-invasive brain stimulation technique (called rTMS) can improve hand strength and movement in people who have had a stroke at least 3 months ago. The treatment is delivered through a coil placed on the scalp and does not require surgery.
Durham, North CarolinaAges 21 years+ - NCT06765733RecruitingEarly Phase 1
Testing Aleeto for multiple system atrophy (MSA)
This trial tests a new treatment called Aleeto for people with a specific type of multiple system atrophy (MSA-P) who haven't responded well to standard Parkinson's medications. The goal is to see if Aleeto is safe and might help improve symptoms.
Beijing, Beijing MunicipalityAges 30–75 - NCT06766279Recruiting
OMT for smell loss after COVID-19
This trial tests if osteopathic manipulative treatment (OMT) can help people regain their sense of smell after COVID-19. OMT is a hands-on therapy used by osteopathic doctors to improve body function.
Las Cruces, New MexicoAges 18 years+ - NCT06766422Recruiting
AI tool to better detect and predict brain aneurysm risk
This study uses artificial intelligence to help doctors better see and understand brain aneurysms from MRI or CT scans. It aims to improve how accurately aneurysms are found and whether they are stable or at risk of rupturing.
ShanghaiAges 18 years+ - NCT06766435Recruiting
A blood test for brain injury after head trauma
This trial tests a new blood test that can help doctors quickly check if you have a brain injury after a head injury. It may help you avoid a CT scan if the blood test shows you are likely fine.
New York, New YorkAges 18 years+ - NCT06766526Recruiting
Online support for emotional adjustment after prostate cancer
This trial tests an online support program to help men cope with emotional distress after prostate cancer. You participate from home using a computer or smartphone.
LinköpingAges 18 years+ - NCT06766916RecruitingPhase 2
Testing Crisugabalin for nerve pain after radiation
This trial tests a drug called Crisugabalin to see if it helps people with nerve pain caused by radiation treatment for head and neck cancer. The study aims to find a better way to manage this type of pain that does not go away.
Fuzhou, FujianAges 18 years+ - NCT06767137Recruiting
Comparing two therapies for insomnia
This study compares two types of talk therapy — BRT (a brief version) and CBT-I (the standard approach) — to see which works better for people with insomnia. You would attend sessions and learn techniques to improve your sleep.
Bern, Canton of BernAges 18–80 - NCT06767631Recruiting
Muscle and nerve changes after botox for stroke foot tightness
This study looks at how botulinum toxin (botox) injections affect the muscles, tendons, and nerves in the lower leg of people who have had a stroke and have a tight, twisted foot (equinovarus). It aims to understand these changes to improve future treatments.
LeuvenAges 40–60 - NCT06767657Recruiting
Immediate vs delayed surgery for recent mini-stroke or mild stroke
This trial compares two approaches for treating a blocked carotid artery after a mini-stroke or mild stroke: surgery done right away (within hours) versus waiting a short while. The goal is to see which timing helps prevent another stroke better.
FlorenceAges 45–90 - NCT06768138RecruitingPhase 3
Giving clot-busting medicine directly into the brain after successful blood flow restoration
This trial tests whether a clot-busting drug given directly into the brain artery can improve recovery after a major stroke caused by a blockage in the front part of the brain. The study is for people whose blood flow has already been successfully restored with standard treatments.
NancyAges 18 years+ - NCT06768190Recruiting
WeLove: WhatsApp support for pregnancy mental health
This pilot study tests a WhatsApp-based support program (WeLove) designed to help pregnant women and their partners prevent emotional distress and sleep problems. If you are in early pregnancy or a partner, you may join a 3‑group study comparing the program to usual care.
Hong KongAges 18 years+ - NCT06768515Recruiting
Organ donation from brain-dead ICU patients
This study looks at how brain-dead patients are cared for in the ICU before organ donation to see if certain practices help with getting more usable organs. It may help improve the donation process for future patients.
ParisAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,462 recruiting neurology studies from the U.S. registry right now, out of 19,649 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.