Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,462 recruiting studies in this area right now.
By phase
- Not applicable9,797
- Phase 2786
- Phase 1574
- Phase 3538
- Phase 4342
- Phase 1/Phase 2304
- Phase 2/Phase 3121
Top conditions
- Stroke854
- Parkinson Disease424
- Multiple Sclerosis342
- Alzheimer Disease340
- Dementia226
- Ischemic Stroke199
- Epilepsy196
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia152
- Traumatic Brain Injury152
- Sarcopenia148
- Acute Ischemic Stroke141
- Cerebral Palsy130
- Mild Cognitive Impairment129
- Pain Management114
- Migraine113
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing95
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- Cairo University63
Where studies are running
- California675
- Massachusetts301
- New York292
- Florida277
- Texas267
- Maryland244
- Arizona216
- Alabama211
- Illinois193
- Pennsylvania177
Recruiting studies12,460 total
- NCT06775561Recruiting
Study of hidden DNA causes for rare neuromuscular and epilepsy diseases
This study is for people with a neuromuscular disease or epilepsy whose genetic testing hasn't found a clear answer. It uses advanced techniques to look at parts of the DNA that don't code for proteins, to find hidden causes and help guide future treatments.
BolognaAges Any age - NCT06775782Recruiting
Remote conditioning for moderate stroke from large artery blockage
This trial tests whether a non-invasive arm cuff treatment (remote ischemic conditioning) can help people recover from a moderate stroke caused by a blockage in a major artery. You must start the treatment within 48 hours of your first symptoms.
Xi'an, ShaanxiAges 18–85 - NCT06775964RecruitingPhase 1/Phase 2
Stem cell therapy for early Alzheimer's disease
This trial tests a stem cell treatment for people with early-stage Alzheimer's disease. It aims to see if the treatment can help slow memory loss or other symptoms. You must have a specific blood test showing inflammation in the body to qualify.
Houston, TexasAges 60–80 - NCT06776419Recruiting
Heart inflammation and scarring in Fabry disease
This study uses advanced heart scans (PET/CT and MRI) to look at inflammation, blood vessel health, and scarring in the hearts of people with Fabry disease. It aims to better understand how Fabry disease affects the heart and find new ways to track or treat these changes.
CopenhagenAges 18 years+ - NCT06776705Recruiting
Low-intensity ultrasound for sleep problems in chronic tinnitus
This trial tests if a gentle ultrasound treatment can improve sleep in people with ongoing tinnitus. It focuses on older adults who have had tinnitus for at least 3 months and struggle with sleep.
Hong Kong, Hong KongAges 60–85 - NCT06776991Recruiting
Social anxiety and public speaking fear study
This study tests if reward processing training combined with exposure therapy helps people with social anxiety disorder who are afraid of public speaking. Participants will complete therapy sessions and possibly an MRI brain scan.
Los Angeles, CaliforniaAges 18–60 - NCT06777134Recruiting
Pelvic floor issues and leg strength in MS patients
This study looks at how pelvic floor problems relate to leg strength and function in people with multiple sclerosis. It may help understand how to better treat these issues.
Istanbul, IstanbulAges 18–65 - NCT06777394Recruiting
High intensity interval training for Down syndrome
This study tests whether high intensity interval training (short bursts of intense exercise) can help children with Down syndrome. Doctors want to see if it improves strength and overall health.
Lahore, Punjab ProvinceAges 3–14 - NCT06777576Recruiting
Self-balancing exoskeleton for spinal cord injury
This trial tests a self-balancing exoskeleton (a wearable robotic suit) to help people with spinal cord injuries stand and walk. It is designed for those with injuries at or above the T6 level and looks at how well the device works and how it feels to use.
The Bronx, New YorkAges 18 years+ - NCT06778005Recruiting
Ultrasound of leg nerves in type 2 diabetes with nerve damage
This study uses ultrasound (an imaging test) to measure the nerves in the legs of people with type 2 diabetes who have nerve damage. It helps doctors learn more about how diabetes affects nerves.
Istanbul, ÜsküdarAges 18–65 - NCT06778135Recruiting
Brain cell study in Parkinson's DBS surgery
This trial studies how brain cells in a specific area (the prefrontal cortex) affect thinking and planning in people with Parkinson's disease who are getting deep brain stimulation (DBS) surgery. The goal is to learn more about brain function to improve future treatments.
Aurora, ColoradoAges 45–85 - NCT06778473Recruiting
Acupuncture plus self-rehab for severe Bell's palsy
This study tests whether combining a gentle type of acupuncture (intradermal acupuncture) with a self-guided rehabilitation program can help people with severe Bell's palsy recover better. It is for adults having their first episode of Bell's palsy with significant facial weakness.
Suzhou, JiangsuAges 18 years+ - NCT06778811RecruitingPhase 4
Sleep quality study for heart surgery patients
This trial studies sleep problems before and after heart surgery. It tests two medicines to see if they can help improve sleep. This may help you recover better after surgery.
Nanjing, JiangsuAges 40–75 - NCT06778772Recruiting
Moving from child to adult epilepsy care
This study helps teens with epilepsy make a smooth switch from a children's hospital to an adult hospital. It looks at how to improve this important transition so you don't miss any care.
PaviaAges 17–18 - NCT06779149Recruiting
Comparing therapy and medication for chronic insomnia
This trial compares two treatments for chronic insomnia: cognitive behavioral therapy (CBT-I) and a medication called lemborexant. It aims to find which works better for different types of insomnia. You may qualify if you have ongoing trouble sleeping and are not taking other sleep aids.
Québec, QuebecAges 18 years+ - NCT06779487Recruiting
Predicting memory changes from brain radiation
This study looks for biomarkers in your blood that might predict how radiation treatment affects brain function. The goal is to understand and possibly reduce cognitive side effects.
Mumbai, MaharashtraAges 5–39 - NCT06779578Recruiting
Comparing two types of radiofrequency for trigeminal neuralgia
This study compares two treatments (bipolar vs monopolar pulsed radiofrequency) for people with trigeminal neuralgia that hasn't improved with medication. It aims to see which method provides better pain relief.
AlexandriaAges Any age - NCT06779799Recruiting
Study of vocal cord lesions in autoimmune disease patients
This study examines vocal cord lesions, like 'bamboo' nodes, that cause voice changes (dysphonia) in people with autoimmune diseases such as lupus or rheumatoid arthritis. It aims to better understand and characterize these lesions to improve diagnosis and treatment.
BrestAges 18 years+ - NCT06779890RecruitingPhase 4
Comparing anesthesia types for brain tumor surgery
This trial compares two types of anesthesia (gas vs. IV) during brain tumor surgery to see which one better protects the brain and helps with thinking and memory after the operation.
ThessalonikiAges 18–80 - NCT06780501Recruiting
Database for people with intellectual disabilities and epilepsy
This trial creates a database of health information from people with intellectual disabilities and epilepsy. It aims to help doctors and researchers learn more about these conditions and improve care. The database includes information from medical records, and some people may also be asked to join a research register for future studies.
BodminAges 18 years+ - NCT06780488Recruiting
Virtual reality balance training for stroke recovery
This trial tests whether a special virtual-reality system that combines head movements and balance exercises can help improve walking and stability for people who have had a stroke. It is designed for those who are at least 6 months past their stroke and can walk with some help.
Roma, RMAges 18–80 - NCT06780709Recruiting
Wellness program for neuromyelitis optica patients
This trial tests a structured wellness program to improve quality of life for people with neuromyelitis optica (NMOSD). It is designed to be accessible for any level of disability.
New York, New YorkAges 18 years+ - NCT06781060Recruiting
Nerve stimulation for sciatic nerve injury in children
This trial tests if electrical nerve stimulation can help children aged 3 to 19 who have nerve damage in the leg caused by an injection. The goal is to improve nerve healing and leg function.
Multan, Punjab ProvinceAges 3–19 - NCT06780995Recruiting
Power exercise for better walking after stroke
This study tests if a power-based exercise program can improve walking and overall recovery for people who had a stroke at least six months ago. It may help you move more easily and feel stronger.
Kelowna, British ColumbiaAges 19 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,462 recruiting neurology studies from the U.S. registry right now, out of 19,649 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.