Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,465 recruiting studies in this area right now.
By phase
- Not applicable9,805
- Phase 2785
- Phase 1574
- Phase 3534
- Phase 4343
- Phase 1/Phase 2304
- Phase 2/Phase 3120
Top conditions
- Stroke856
- Parkinson Disease424
- Alzheimer Disease341
- Multiple Sclerosis341
- Dementia228
- Ischemic Stroke199
- Epilepsy195
- Obstructive Sleep Apnea154
- Spinal Cord Injuries153
- Traumatic Brain Injury153
- Insomnia152
- Sarcopenia149
- Acute Ischemic Stroke141
- Cerebral Palsy130
- Mild Cognitive Impairment129
- Migraine113
- Pain Management112
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing95
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota63
Where studies are running
- California673
- Massachusetts304
- New York293
- Florida278
- Texas268
- Maryland244
- Alabama213
- Arizona213
- Illinois193
- Pennsylvania177
Recruiting studies12,463 total
- NCT06941532Recruiting
Study of GMP powder for PKU and tyrosinemia
This trial tests a new powdered protein substitute (GMP) for people with PKU or tyrosinemia. It aims to see if it is a safe and effective option to help manage their condition.
BirminghamAges 3 years+ - NCT06941584Recruiting
AIRE gene's role in autoimmune nerve diseases
This study looks at how the AIRE gene affects people with autoimmune nerve diseases like NMOSD, myasthenia gravis, and autoimmune encephalitis when they also have other autoimmune conditions. It may help researchers understand why some people get multiple autoimmune problems.
RomaAges 18 years+ - NCT06941662Recruiting
Huntington's disease biobank: remote monitoring study
This study is building a biobank to better understand Huntington's disease by using remote monitoring and deep phenotyping (collecting detailed health information). It may help develop better ways to track the disease and improve care for people with the Huntington's gene expansion.
Palo Alto, CaliforniaAges Any age - NCT06941961Recruiting
Brain stimulation therapy after stroke clot removal
This trial tests if a non-invasive brain stimulation technique called iTBS can help people recover motor function after a stroke caused by a large clot in the front part of the brain. It is for patients who had the clot removed successfully with a procedure within 24 hours of symptoms starting.
Changchun, JilinAges 18–85 - NCT06942039RecruitingEarly Phase 1
Study of two drugs for young children with aggressive brain tumors
This trial tests a combination of chemotherapy drugs (topotecan given into the spine plus maintenance chemo) for children under 6 with high-risk embryonal brain tumors. The goal is to see if this approach can improve outcomes after initial treatment.
Calgary, AlbertaAges Up to 6 years - NCT06942455Recruiting
Better sleep for urban Latino middle schoolers
This study tests a sleep hygiene program to improve sleep health in Latino children aged 11-13 who sleep 9 hours or less per night. It aims to help kids get better rest and feel better overall.
Providence, Rhode IslandAges 11–13 - NCT06942533Recruiting
Using SpiroGym app to help Parkinson's breathing
This trial tests whether using a mobile app that gives visual feedback while doing breathing exercises can improve symptoms in people with Parkinson's disease. It may help you if you are on stable medication.
PragueAges 40–80 - NCT06943170Recruiting
Aerobic exercise with or without a low calorie diet for teens with Down syndrome
This trial studies how aerobic exercise, alone or combined with a low calorie diet, affects body fat and weight in children with Down syndrome who are overweight or obese. The goal is to find a safe, effective way to help manage weight.
Lahore, Punjab ProvinceAges 8–16 - NCT06943508Recruiting
Nordic walking for balance in children with Down syndrome
This study tests whether a special walking program (Nordic walking with poles) can help children with Down syndrome improve their balance and leg strength. It may be a good fit for children who can walk but have balance difficulties.
Lahore, Punjab ProvinceAges 8–13 - NCT06943586Recruiting
Stroke genetics: testing a heart medicine's fit
This trial tests whether a quick genetic test can help choose the right antiplatelet medicine for people who have had a mild stroke or a high-risk mini-stroke (TIA). The goal is to see if this personalized approach is possible in a hospital setting.
Birmingham, AlabamaAges 18–89 - NCT06943625Recruiting
Green light and brain stimulation for migraine
This trial tests whether combining green light therapy with a gentle brain stimulation technique (transcranial direct current stimulation, or tDCS) can help reduce migraine pain. It may be an option for people with frequent migraines who have not found relief from other treatments.
Rawalpindi, Punjab ProvinceAges 18 years+ - NCT06943729Recruiting
Testing a flow-diverter stent for brain aneurysms
This trial tests a flow-diverter stent (a small mesh tube) to treat brain aneurysms that are hard to close with standard methods. It may help if you have a wide-neck or other complex aneurysm that hasn't burst.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06943885Recruiting
Mobile Stroke Unit vs Standard Ambulance for Stroke
This study compares a special ambulance equipped with a CT scanner and video link to stroke doctors (mobile stroke unit) versus standard emergency services for people having a stroke. It tests whether getting faster, specialized care on the way to the hospital improves recovery.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06944171Recruiting
How brain-related challenges affect daily life in children with cerebral palsy
This study looks at how impairments like muscle stiffness or weakness affect daily activities and participation in children (ages 6–12) with cerebral palsy. It could help families better understand their child's needs.
AnkaraAges 6–12 - NCT06944782Recruiting
Can mouth muscle tests help diagnose sleep apnea?
This study tests a new device that measures muscle activity in your mouth to diagnose sleep apnea—without needing to spend the night in a lab. If you've already had a sleep test showing either no sleep apnea or moderate to severe sleep apnea, and you're not using CPAP daily, you may be able to help.
San Diego, CaliforniaAges 18–80 - NCT06945081Recruiting
Measuring skin elasticity in Wilson's disease patients on D-Penicillamine
This study checks if D-Penicillamine, a treatment for Wilson's disease, causes skin damage by measuring skin elasticity on the forearm and cheek. It compares results between patients taking the drug and healthy volunteers matched by age and sex.
BronAges 12 years+ - NCT06945185Recruiting
Motor imagery training for arm strength after stroke
This trial tests if imagining arm movements (motor imagery training) can help improve arm strength in people who had a stroke at least 6 months ago. It is a non-drug, mental practice approach that may help your brain relearn movement.
IslamabadAges 45 years+ - NCT06945211Recruiting
Mirror therapy for arm movement after stroke
This study tests whether doing arm exercises while watching the reflection of your good arm in a mirror can help improve movement and function in your affected arm after a stroke.
IslamabadAges 45 years+ - NCT06945848Recruiting
Stenting for Intracranial Hypertension on Acetazolamide
This trial tests whether placing a stent (a small tube) in a narrowed brain vein can help reduce pressure in the head in people with Intracranial Hypertension who have been on acetazolamide for over a year. It may be an option if you still have high pressure despite medication.
MontpellierAges 18 years+ - NCT06946082Recruiting
Stroke study: arm and language skills in Turkish speakers
This study looks at how arm movement, body control, and mental imagery (imagining movement without actually doing it) relate to Turkish language abilities after a stroke. It aims to understand how these functions work together to help recovery.
IzmirAges 18 years+ - NCT06946563Recruiting
Fetoscopic surgery for spina bifida before birth
This trial tests a special fetal surgery (fetoscopic repair) to fix spina bifida before birth. It might help reduce spine and brain damage in babies with this condition.
Portland, OregonAges 18 years+ - NCT06946940RecruitingPhase 2
Cannabis oil for fibromyalgia pain
This trial tests whether cannabis oil can help people with fibromyalgia who still have pain despite trying other treatments. Participants will receive cannabis oil, and researchers will look for biological markers that predict who responds best.
HaifaAges 30 years+ - NCT06947343Recruiting
Action observation vs motor relearning for stroke balance
This study compares two types of therapy—watching actions and a standard motor relearning program—to see which helps stroke survivors improve their balance and walking. If you are able to stand briefly, you may benefit from this extra rehab.
IslamabadAges 45 years+ - NCT06947512Recruiting
Personalized reading help for children with difficulties
This trial tests whether customizing on-screen characters and text-to-speech can improve reading skills in children aged 7 to 15 who either have dyslexia, specific reading disorder, or other significant reading and writing challenges. It also includes a group of typical readers for comparison.
Bosisio Parini, LCAges 7–15
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,465 recruiting neurology studies from the U.S. registry right now, out of 19,759 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.