Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,465 recruiting studies in this area right now.
By phase
- Not applicable9,805
- Phase 2785
- Phase 1574
- Phase 3534
- Phase 4343
- Phase 1/Phase 2304
- Phase 2/Phase 3120
Top conditions
- Stroke856
- Parkinson Disease424
- Alzheimer Disease341
- Multiple Sclerosis341
- Dementia228
- Ischemic Stroke199
- Epilepsy195
- Obstructive Sleep Apnea154
- Spinal Cord Injuries153
- Traumatic Brain Injury153
- Insomnia152
- Sarcopenia149
- Acute Ischemic Stroke141
- Cerebral Palsy130
- Mild Cognitive Impairment129
- Migraine113
- Pain Management112
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing95
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota63
Where studies are running
- California673
- Massachusetts304
- New York293
- Florida278
- Texas268
- Maryland244
- Alabama213
- Arizona213
- Illinois193
- Pennsylvania177
Recruiting studies12,463 total
- NCT06937164Recruiting
Blood pressure and isometric exercise in inactive adults
This study tests how isometric (holding still) exercises affect blood pressure in people who don't exercise much. It might help find safe ways to lower blood pressure without medication.
Canterbury, KentAges 18–55 - NCT06937255Recruiting
Language and reading risk in monolingual and multilingual children
This study tests a new way to identify children who may have trouble learning to read or speak Italian. It helps compare children who speak only Italian with those who also speak another language at home.
Bosisio Parini, LCAges 4–9 - NCT06937541Recruiting
Family support in dementia mental health wards
This study is about improving care for people with dementia in mental health hospital wards. Researchers want to hear from family carers, people with dementia themselves, and staff to understand experiences and design better support.
LondonAges Any age - NCT06937723Recruiting
App-based monitoring for spasticity in multiple sclerosis
This trial tests if a smartphone app can help monitor spasticity (muscle tightness or stiffness) in people with multiple sclerosis. If you have MS and spasticity that needs treatment, using your own smartphone might help track your health.
Düsseldorf, North Rhine-WestphaliaAges 18 years+ - NCT06938100Recruiting
CADASIL Study: Genes, Brain Scans and Symptoms
This study looks at how genetic and brain imaging changes relate to symptoms in people with CADASIL, a genetic condition that affects small blood vessels in the brain and can cause strokes. It aims to better understand the disease to improve future care.
MilanAges 18 years+ - NCT06938243RecruitingPhase 1
Vagus Nerve Stimulation for Early Stroke Arm Recovery
This trial tests whether a device called a vagus nerve stimulator (VNS), placed under the skin, is safe and helps improve arm function when started 3 months after a stroke. It is for people with moderate to severe arm weakness who can still move their arm a little.
Jinan, ShandongAges 30–75 - NCT06938581Recruiting
ERAS Recovery Steps for Breast-Conserving Surgery
This study tests a set of recovery steps called ERAS (Enhanced Recovery After Surgery) for people having breast-conserving surgery. The goal is to help you heal faster, feel more comfortable, and get back to your normal life sooner.
Omaha, NebraskaAges 19 years+ - NCT06938763RecruitingPhase 1
Safety study of J4 in healthy volunteers
This trial tests a new drug called J4 in healthy adults to see if it is safe and how the body processes it. Healthy volunteers aged 18 to 64 may join to help researchers learn about the drug's effects.
TaipeiAges 18–64 - NCT06938789Recruiting
Bleeding and confusion after hip fracture in older adults
This study looks at how bleeding after a hip fracture might affect confusion (delirium) in older adults. It will help doctors understand how to better manage bleeding to prevent confusion.
Aarhus, Central JutlandAges 75 years+ - NCT06939153Recruiting
How age, sex, and exercise affect the heart when blood flow drops
This study looks at how your heart and blood vessels work together when blood flow to your legs is reduced using a special chamber. It compares younger and older adults, and men and women, especially after light exercise.
Boston, MassachusettsAges 18 years+ - NCT06939166RecruitingEarly Phase 1
Immune cell therapy for relapsed neurological autoimmune diseases
This trial tests a new type of immune cell therapy (CAR T-cells) that targets CD19 and BCMA proteins on B cells. It is for people with certain neurological autoimmune diseases that have come back or not responded to standard treatments. The goal is to see if this therapy can help control the disease.
TianjinAges 18 years+ - NCT06939348Recruiting
Ultrasound therapy for patients with consciousness disorders
This trial tests whether ultrasound stimulation can help people with disorders of consciousness, like coma or a minimally conscious state. It aims to improve brain function and recovery for patients who have been injured for over a month.
Los Angeles, CaliforniaAges 18–79 - NCT06939660Recruiting
Brain-spinal cord stimulation for walking after spinal cord injury
This trial tests if combining brain-computer interface technology with spinal cord stimulation can help improve walking in people with chronic spinal cord injury. It aims to see if this approach works when standard rehab has stopped helping.
Beijing, Beijing MunicipalityAges 14–65 - NCT06940128Recruiting
Ischemic conditioning after stroke clot removal
This trial tests a method called direct ischemic conditioning, which is a gentle way to prepare your brain to better handle the return of blood flow after a stroke. It is for people who have had a large artery blockage in the front part of the brain and have already had a successful procedure to reopen the artery.
Shengyang, LiaoningAges 18 years+ - NCT06940284Recruiting
Food intake and health in hospitalized elderly
This study looks at how much food older adults eat while in the hospital and whether that affects their muscles and recovery. It may help understand the role nutrition plays in staying strong during a hospital stay.
São Paulo, São PauloAges 65 years+ - NCT06940336RecruitingPhase 4
Testing tafamidis for transthyretin amyloid polyneuropathy
This trial tests whether the drug tafamidis can help people with a specific type of nerve damage caused by abnormal protein buildup. It aims to slow or improve symptoms in adults with this condition.
JinanAges 18–80 - NCT06940323Recruiting
Pregnancy study for women with chronic conditions
This study tracks pregnant women with certain chronic health conditions (like multiple sclerosis, lupus, or rheumatoid arthritis) and healthy pregnant women as a comparison group. It aims to understand how these conditions and their treatments affect pregnancy, the baby, and breast milk.
San Francisco, CaliforniaAges 18–64 - NCT06940635Recruiting
Hand therapy for stroke: may help speech and swallowing
This study tests whether a special hand therapy using brain-computer interface and electrical stimulation can also help improve speech and swallowing problems after a stroke. You may be eligible if you're at least 3 months past your stroke, have some arm weakness, and have aphasia or dysphagia.
Innsbruck, TyrolAges 18 years+ - NCT06940908Recruiting
Living with Guillain-Barré syndrome as a child
This study interviews children who had Guillain-Barré syndrome (GBS) to understand their experiences after recovery. It may help doctors better support young patients with GBS.
Montpellier, OccitanieAges 10–18 - NCT06940934Recruiting
Acandis device study for brain aneurysms
This study is checking how well Acandis devices work for treating brain aneurysms in real-world use. If you have a brain aneurysm that can be treated with an Acandis device, this trial may help your doctor understand your treatment options.
RouenAges 18 years+ - NCT06941129RecruitingPhase 1
CAR T-cell therapy for resistant autoimmune diseases
This trial tests a new type of immune therapy called CAR T-cells that target two markers on your B cells (CD19 and BCMA). It is for people with certain autoimmune diseases that have not improved or have come back after standard treatments. The goal is to see if this therapy can help control the disease.
TianjinAges 18 years+ - NCT06940986Recruiting
Holistic pain self-management for military health system patients
This trial tests a holistic pain self-management program for people with long-term muscle or bone pain. It aims to help you take control of your pain through education and support, without relying only on medications.
Fairbanks, AlaskaAges 18 years+ - NCT06941012Recruiting
Measuring alpha-synuclein changes in Parkinson's disease progression
This study examines changes in alpha-synuclein, a protein linked to Parkinson's, to better understand how the disease progresses. It may help researchers learn more about Parkinson's and improve future care.
ThessalonikiAges 18–85 - NCT06941025Recruiting
Safety of Elfabrio in pregnant and breastfeeding women with Fabry disease
This study follows women with Fabry disease who took the medicine Elfabrio during pregnancy or breastfeeding to see if it is safe for them and their babies. It helps doctors learn more about how this treatment affects mothers and infants.
Washington D.C., District of ColumbiaAges Any age
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,465 recruiting neurology studies from the U.S. registry right now, out of 19,759 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.