Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,465 recruiting studies in this area right now.
By phase
- Not applicable9,805
- Phase 2785
- Phase 1574
- Phase 3534
- Phase 4343
- Phase 1/Phase 2304
- Phase 2/Phase 3120
Top conditions
- Stroke856
- Parkinson Disease424
- Alzheimer Disease341
- Multiple Sclerosis341
- Dementia228
- Ischemic Stroke199
- Epilepsy195
- Obstructive Sleep Apnea154
- Spinal Cord Injuries153
- Traumatic Brain Injury153
- Insomnia152
- Sarcopenia149
- Acute Ischemic Stroke141
- Cerebral Palsy130
- Mild Cognitive Impairment129
- Migraine113
- Pain Management112
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing95
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota63
Where studies are running
- California673
- Massachusetts304
- New York293
- Florida278
- Texas268
- Maryland244
- Alabama213
- Arizona213
- Illinois193
- Pennsylvania177
Recruiting studies12,463 total
- NCT06992752Recruiting
Trial on breathing problems in people with thoracic outlet syndrome
This study looks at whether people with thoracic outlet syndrome (TOS) have different breathing patterns and how that might relate to their symptoms. If you have had TOS pain for more than 6 months, you may be able to help researchers understand this condition better.
Ankara, AltındağAges 18–65 - NCT06992804RecruitingEarly Phase 1
Light therapy and lecanemab for mild Alzheimer's
This trial tests whether a special near-infrared light device, combined with the medication lecanemab, can help people with mild Alzheimer's disease. It aims to see if the light therapy can slow down memory loss and improve daily function.
BeijingAges 50–90 - NCT06992973Recruiting
Radiation before surgery for large brain metastases
This trial tests a new approach for people with a single large brain tumor that has spread from another cancer. You would receive a short, focused dose of radiation (stereotactic radiosurgery) in small, separate treatments, followed by surgery to remove the tumor. The goal is to see if this combination works better than the usual treatment.
RomeAges 18 years+ - NCT06993207Recruiting
Home brain monitoring study for cognitive decline
This study uses a special EEG headband to monitor brain activity at home in older adults. It aims to understand cognitive decline, including Alzheimer's and mild memory problems, and compare results with healthy volunteers.
Zaragoza, ZaragozaAges 60 years+ - NCT06993844RecruitingPhase 1/Phase 2
Study of ETX-636 for advanced solid tumors with PIK3CA mutation
This trial tests an experimental drug called ETX-636 in people whose cancer has a specific gene change (PIK3CA mutation) and has not responded to at least one prior treatment. The goal is to see if the drug can shrink tumors or stop them from growing.
Newport Beach, CaliforniaAges 18 years+ - NCT06994247Recruiting
Boosting CPAP use in severe sleep apnea
This study tests whether motivation and psychological support can help people with severe sleep apnea use their CPAP machine more consistently over three months.
Split, DalmatiaAges 18 years+ - NCT06994975RecruitingPhase 3
Stroke drug test for patients who missed the 4.5 hour window
This trial tests a clot-busting drug for people who had a stroke more than 4.5 hours ago. It uses a special CT scan to see if the treatment can still help them.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06995040Recruiting
Brain resilience after minor stroke study
This study looks at how the brain heals after a minor stroke by analyzing your genes and brain MRI over time. It aims to understand why some people recover better than others.
BrestAges 18 years+ - NCT06995313Recruiting
Biofeedback training for hemianopia
This trial tests a biofeedback training program for people with hemianopia (vision loss on one side) that started more than 6 months ago. The training uses visual and sound cues to help you make better use of your remaining vision.
Toronto, OntarioAges 18–90 - NCT06995573RecruitingPhase 1/Phase 2
Testing a new Alzheimer's drug (NSC001) for safety and early effectiveness
This study tests a new drug called NSC001 for people with mild to moderate Alzheimer's. It checks if the drug is safe and if it might help slow memory decline. You'll need a caregiver who can join you at visits and help track your progress.
Salzburg, State of SalzburgAges 50–85 - NCT06995534Recruiting
Splint or Exercise for De Quervain's Wrist Pain
This trial compares wearing a splint versus doing specific exercises to treat De Quervain's tenosynovitis, a condition that causes wrist pain and swelling. It may help if you have new or worsening wrist pain without other injuries or diseases.
KonyaAges 18–65 - NCT06995729RecruitingPhase 1
Testing zavegepant nasal spray in children with migraines
This trial tests whether the medicine zavegepant (given as a nasal spray) is safe and works well for children aged 6 to 11 who have a history of migraines. If your child gets migraines, this study may help find a new treatment option.
Little Rock, ArkansasAges 6–11 - NCT06995742Recruiting
Effect of a vital sign device on staff workload
This study tests whether using a special device (ANNE One-Wellue) to monitor vital signs reduces how often hospital staff need to take measurements manually. It is for patients staying on a specific hospital unit.
Chicago, IllinoisAges 18 years+ - NCT06996171Recruiting
Magnesium and melatonin for insomnia in young adults
This trial compares two natural supplements—magnesium and a melatonin-like compound—to see which works better for helping young adults fall asleep and stay asleep. It is for people with primary insomnia (trouble sleeping without another medical cause).
Kharan, Punjab ProvinceAges 18–40 - NCT06996509Recruiting
Noninvasive breathing support for Guillain-Barré syndrome
This trial tests whether noninvasive breathing support (like a mask or nasal prongs) can help people with Guillain-Barré syndrome who have trouble breathing. It aims to see if this approach can avoid the need for a breathing tube.
Asyut, AssuitAges 18 years+ - NCT06996600Recruiting
Study of a device to check CSF shunt flow and headaches
This trial is testing a wearable thermal device that checks if your CSF shunt is working properly. It may help understand if your headaches are linked to shunt problems. The study involves using the device at home for 30 days and going to a few follow-up visits.
Chicago, IllinoisAges 6–80 - NCT06997484RecruitingPhase 1
Testing safety of HL-400 in healthy adults
This study tests a new drug called HL-400 for the first time in people. It checks how safe the drug is and how the body handles it, to see if it could be developed for future patients.
Baltimore, MarylandAges 18–65 - NCT06998303Recruiting
Brain imaging study for Parkinson's DBS patients
This study uses MRI scans to look at brain activity in people with Parkinson's disease who have a Medtronic Percept DBS device. The goal is to better understand how deep brain stimulation works.
Minneapolis, MinnesotaAges 21 years+ - NCT06998485Recruiting
Arm recovery after a first stroke
This study tests an intensive 6-week arm training program for people who had a first stroke 3 to 6 months ago and still have arm weakness. The goal is to see how the brain can recover arm function.
Boston, MassachusettsAges 18 years+ - NCT06999096Recruiting
Long-read gene testing for inherited movement disorders
This study uses a new DNA reading method to find hidden genetic causes of dystonia. It is for people with dystonia who had standard genetic testing that did not find a cause.
MontpellierAges Any age - NCT06999161Recruiting
Tracking Antibiotic Levels in ICU Brain Injury Patients
This study monitors the amount of certain antibiotics in the blood of patients with acute brain injury in the intensive care unit. It aims to make sure the antibiotics are at the right level to fight infection, especially in patients whose kidneys are clearing drugs faster than normal.
NîmesAges 18 years+ - NCT06999434RecruitingPhase 1
Testing a new PET scan for nerve coating damage
This study uses a special PET scan tracer to look at the protective coating of nerves in the brain. It aims to help doctors see and measure damage to this coating, which can happen in diseases like multiple sclerosis. The trial is open to healthy volunteers to test this new imaging method.
New Haven, ConnecticutAges 18–90 - NCT06999577RecruitingPhase 4
The Mechanism Versus PPI Trial for throat reflux
This study tests how well omeprazole (a common acid-blocking medicine) works for people with laryngopharyngeal reflux (LPR), a condition where stomach acid irritates the throat. If you have had throat symptoms for more than 8 weeks and are already scheduled for an endoscopy with acid monitoring, you may qualify to see if this medicine helps more than a placebo.
San Deigo, CaliforniaAges 18–89 - NCT06999811Recruiting
Technology vs. medication monitoring for buprenorphine in pregnancy
This study compares two approaches to help pregnant people stay on buprenorphine (a medication for opioid use disorder): one uses technology to support therapy, and the other uses standard medication monitoring. It aims to see which method works better for keeping you in treatment during pregnancy.
Charleston, South CarolinaAges 18–45
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,465 recruiting neurology studies from the U.S. registry right now, out of 19,759 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.