Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,473 recruiting studies in this area right now.
By phase
- Not applicable9,815
- Phase 2785
- Phase 1573
- Phase 3534
- Phase 4343
- Phase 1/Phase 2304
- Phase 2/Phase 3119
Top conditions
- Stroke856
- Parkinson Disease424
- Alzheimer Disease341
- Multiple Sclerosis341
- Dementia228
- Ischemic Stroke199
- Epilepsy195
- Obstructive Sleep Apnea155
- Traumatic Brain Injury154
- Insomnia152
- Spinal Cord Injuries151
- Sarcopenia149
- Acute Ischemic Stroke141
- Cerebral Palsy130
- Mild Cognitive Impairment129
- Migraine113
- Pain Management112
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital135
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing95
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University71
- National Taiwan University Hospital70
- University of Minnesota63
Where studies are running
- California674
- Massachusetts306
- New York293
- Florida277
- Texas270
- Maryland245
- Arizona213
- Alabama212
- Illinois193
- Pennsylvania177
Recruiting studies12,471 total
- NCT06996171Recruiting
Magnesium and melatonin for insomnia in young adults
This trial compares two natural supplements—magnesium and a melatonin-like compound—to see which works better for helping young adults fall asleep and stay asleep. It is for people with primary insomnia (trouble sleeping without another medical cause).
Kharan, Punjab ProvinceAges 18–40 - NCT06996509Recruiting
Noninvasive breathing support for Guillain-Barré syndrome
This trial tests whether noninvasive breathing support (like a mask or nasal prongs) can help people with Guillain-Barré syndrome who have trouble breathing. It aims to see if this approach can avoid the need for a breathing tube.
Asyut, AssuitAges 18 years+ - NCT06996600Recruiting
Study of a device to check CSF shunt flow and headaches
This trial is testing a wearable thermal device that checks if your CSF shunt is working properly. It may help understand if your headaches are linked to shunt problems. The study involves using the device at home for 30 days and going to a few follow-up visits.
Chicago, IllinoisAges 6–80 - NCT06997484RecruitingPhase 1
Testing safety of HL-400 in healthy adults
This study tests a new drug called HL-400 for the first time in people. It checks how safe the drug is and how the body handles it, to see if it could be developed for future patients.
Baltimore, MarylandAges 18–65 - NCT06998303Recruiting
Brain imaging study for Parkinson's DBS patients
This study uses MRI scans to look at brain activity in people with Parkinson's disease who have a Medtronic Percept DBS device. The goal is to better understand how deep brain stimulation works.
Minneapolis, MinnesotaAges 21 years+ - NCT06998485Recruiting
Arm recovery after a first stroke
This study tests an intensive 6-week arm training program for people who had a first stroke 3 to 6 months ago and still have arm weakness. The goal is to see how the brain can recover arm function.
Boston, MassachusettsAges 18 years+ - NCT06999096Recruiting
Long-read gene testing for inherited movement disorders
This study uses a new DNA reading method to find hidden genetic causes of dystonia. It is for people with dystonia who had standard genetic testing that did not find a cause.
MontpellierAges Any age - NCT06999161Recruiting
Tracking Antibiotic Levels in ICU Brain Injury Patients
This study monitors the amount of certain antibiotics in the blood of patients with acute brain injury in the intensive care unit. It aims to make sure the antibiotics are at the right level to fight infection, especially in patients whose kidneys are clearing drugs faster than normal.
NîmesAges 18 years+ - NCT06999434RecruitingPhase 1
Testing a new PET scan for nerve coating damage
This study uses a special PET scan tracer to look at the protective coating of nerves in the brain. It aims to help doctors see and measure damage to this coating, which can happen in diseases like multiple sclerosis. The trial is open to healthy volunteers to test this new imaging method.
New Haven, ConnecticutAges 18–90 - NCT06999577RecruitingPhase 4
The Mechanism Versus PPI Trial for throat reflux
This study tests how well omeprazole (a common acid-blocking medicine) works for people with laryngopharyngeal reflux (LPR), a condition where stomach acid irritates the throat. If you have had throat symptoms for more than 8 weeks and are already scheduled for an endoscopy with acid monitoring, you may qualify to see if this medicine helps more than a placebo.
San Deigo, CaliforniaAges 18–89 - NCT06999811Recruiting
Technology vs. medication monitoring for buprenorphine in pregnancy
This study compares two approaches to help pregnant people stay on buprenorphine (a medication for opioid use disorder): one uses technology to support therapy, and the other uses standard medication monitoring. It aims to see which method works better for keeping you in treatment during pregnancy.
Charleston, South CarolinaAges 18–45 - NCT06999850Recruiting
Stair Test with Motion Sensors
This study tests a new way to measure how well people climb stairs using small motion sensors. It includes people with different conditions and healthy volunteers to see if the test works for everyone.
Bosisio Parini, LeccoAges 4–80 - NCT07000409Recruiting
Ultrasound-guided nerve block for shingles pain
This trial tests if a nerve block with betamethasone can reduce long-term shingles pain on the trunk. It may help people who still have pain more than 3 months after the rash appeared.
CairoAges 18–75 - NCT07000461Recruiting
Doppler test to predict memory problems after heart surgery
This study uses a noninvasive ultrasound test (transcranial Doppler) before heart surgery to see if it can help predict thinking or memory problems that may occur after the operation.
IstanbulAges 18–70 - NCT07000851Recruiting
Brain Imaging Study in Corticobasal Syndrome
This study uses MRI scans to look at the brain in people with Corticobasal Syndrome (CBS). It aims to better understand the condition and may help find better ways to diagnose or treat it.
Rochester, MinnesotaAges 18 years+ - NCT07001111Recruiting
Taping therapy for cubital tunnel syndrome pain
This trial tests if a special tape placed on the arm can help reduce pain and improve symptoms in people with cubital tunnel syndrome. It may be a good option if you have arm pain and have not had surgery or certain injections recently.
Istanbul, UskudarAges 18–65 - NCT07001059Recruiting
Ultrasound to see nerve swelling in giant cell arteritis
This trial uses an ultrasound to check for swelling around the optic nerve in people who may have giant cell arteritis (GCA). It aims to see if this test can help diagnose GCA faster.
Aix-en-ProvenceAges 50 years+ - NCT07001150RecruitingPhase 2
Silymarin for nerve protection and symptom control in Parkinson's
This trial tests if silymarin, a natural plant extract, can help protect nerves and improve symptoms in people with Parkinson's disease who are already taking dopamine replacement therapy. It aims to see if adding silymarin can provide extra benefits.
Tanta, Tanta, Qism 2Ages 45–65 - NCT07001852Recruiting
Endovascular therapy for late window stroke patients selected by automated CT
This trial tests whether removing a clot from a large brain artery up to 72 hours after a stroke helps people recover better than standard care. It uses a special computer program on a regular CT scan to decide who might benefit.
Iowa City, IowaAges 18–80 - NCT07001891Recruiting
Brain activity study for restless legs syndrome
This study looks at brain connections related to body awareness in people with restless legs syndrome (RLS). It may help researchers understand RLS better.
BordeauxAges 18–70 - NCT07002437Recruiting
Low oxygen for early spinal cord recovery
This study tests whether mild, short-term low oxygen levels (like at high altitude) can help the spinal cord recover earlier after an injury. It is for people who had a spinal cord injury in the last 2 weeks to 6 months.
Jacksonville, FloridaAges 18–70 - NCT07002580Recruiting
Knee surgery pain relief: nerve block comparison
This study compares two types of nerve blocks (iPACK and adductor canal block) to see which provides better pain relief after arthroscopic knee surgery. It may help you have less pain and recover faster.
SakaryaAges 18–50 - NCT07002892Recruiting
Injection treatments for moderate carpal tunnel syndrome
This study compares two injection treatments (corticosteroid with dextrose versus ozone) for carpal tunnel syndrome. It may help if your CTS is moderate and other treatments haven't worked.
AnkaraAges 18–65 - NCT07003399Recruiting
Breathing Muscle Function in Sleep Apnea and COPD
This study looks at how the diaphragm (the main breathing muscle) and the drive to breathe work in people with sleep apnea, COPD, or both. Researchers want to compare these groups with healthy volunteers to better understand breathing problems.
Nanjing, JiangsuAges 18–80
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,473 recruiting neurology studies from the U.S. registry right now, out of 19,792 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.