Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,487 recruiting studies in this area right now.
By phase
- Not applicable9,830
- Phase 2786
- Phase 1573
- Phase 3532
- Phase 4343
- Phase 1/Phase 2304
- Phase 2/Phase 3119
Top conditions
- Stroke855
- Parkinson Disease423
- Alzheimer Disease341
- Multiple Sclerosis341
- Dementia229
- Ischemic Stroke200
- Epilepsy195
- Obstructive Sleep Apnea155
- Traumatic Brain Injury154
- Insomnia153
- Spinal Cord Injuries151
- Sarcopenia149
- Acute Ischemic Stroke141
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital135
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University71
- National Taiwan University Hospital69
- University of Minnesota63
Where studies are running
- California673
- Massachusetts306
- New York293
- Florida278
- Texas270
- Maryland245
- Alabama213
- Arizona212
- Illinois193
- Pennsylvania177
Recruiting studies12,485 total
- NCT07304375Recruiting
Exercise and sleep effects on learning and abilities in MS
This trial tests how combining exercise and sleep monitoring can improve motor learning and daily function in people with early relapsing-remitting multiple sclerosis. It may help you move better and feel more capable in daily life.
CopenhagenAges 18–70 - NCT07304518RecruitingPhase 2
PRT-064040 nasal spray for migraine in adults
This trial tests a new nasal spray, PRT-064040, to see if it can help treat migraine attacks. It is for adults who have had migraines for at least a year and get 2 to 8 moderate to severe migraines per month.
Beijing, Beijing MunicipalityAges 18–75 - NCT07304674Recruiting
Primary Aldosteronism and Thinking Ability Study
This study looks at whether primary aldosteronism (a treatable cause of high blood pressure) is linked to memory and thinking problems. It may help understand if managing this condition can protect brain health.
Chengdu, SichuanAges 40 years+ - NCT07304739RecruitingPhase 2
Furmonertinib plus radiation and chemo for EGFR lung cancer with brain spread
This trial tests a combination of a targeted pill (furmonertinib), chemotherapy into the spinal fluid, and precise radiation for people with a specific type of lung cancer (EGFR-mutant adenocarcinoma) that has spread to both the brain and the lining around the brain. The goal is to see if this combination can better control the cancer and improve symptoms.
Cangzhou, HebeiAges 18–75 - NCT07304947Recruiting
Guiding blood flow during Moyamoya surgery in children
This study tests if careful monitoring and management of blood flow during surgery can help children with Moyamoya disease recover better after EDAS. It aims to improve safety and outcomes by adjusting treatment based on real-time heart function.
SeoulAges 1 month–18 years - NCT07305168Recruiting
Breathing after tonsil surgery in children with sleep apnea
This study looks at breathing problems that can happen after tonsil or adenoid surgery in children who have sleep apnea. Researchers want to learn more so they can make surgery safer for kids.
Edegem, AntwerpAges 1–18 - NCT07306052Recruiting
Spinal cord stimulation to help walk again after injury
This trial tests whether placing a small device on the spinal cord can help people with spinal cord injuries regain the ability to walk. It is designed for those who have had a traumatic injury and still have some movement in their upper body.
Hangzhou, ZhejiangAges 16–70 - NCT07306104Recruiting
Long-term daily brain stimulation with mild electromagnets for Parkinson's
This trial tests whether daily, long-term use of pulsed electromagnetic fields applied to the head can help reduce Parkinson's symptoms. It is for people with mild to moderate Parkinson's who are not on certain blood thinners and have no major health complications like other neurological diseases or active implants.
OdenseAges 18 years+ - NCT07307508Recruiting
Scalp block for headache after aneurysm bleeding
This trial tests if a scalp nerve block can better manage severe headaches after a brain aneurysm rupture. It is for patients who had an aneurysm treated with coiling in the intensive care unit.
DohaAges 18 years+ - NCT07307560Recruiting
High-flow oxygen during sedation for sleep apnea patients having endoscopy
This study tests if high-flow nasal oxygen can prevent oxygen drops during sedated endoscopy in patients with severe obstructive sleep apnea. It may help people who are at higher risk of breathing problems during the procedure.
Hangzhou, ZhejiangAges 18 years+ - NCT07307846Recruiting
Steroid injection for neck pain and arm feeling
This study tests whether a steroid injection in the neck can improve your sense of arm position (proprioception) along with pain. It may help if you have chronic neck pain that travels down one arm due to a herniated disc.
Pendik, IstanbulAges 18–65 - NCT07307989RecruitingPhase 2
Statin plus ezetimibe vs. statin alone after stroke
This trial compares two treatments for people who recently had a stroke or TIA and have high cholesterol with artery plaque. Some participants will get a combination of two cholesterol-lowering medicines (statin and ezetimibe), while others will get only a statin.
PoziAges 20–100 - NCT07308314Recruiting
Taining County chronic disease management study
This study looks at how to manage chronic diseases (like diabetes or high blood pressure) better for people living in Taining County. It involves completing a survey and regular check-ins over the next few years.
Fuzhou, FujianAges 18 years+ - NCT07308704Recruiting
Using AI to spot heart muscle disease on echocardiograms
This study at Mayo Clinic is testing an artificial intelligence (AI) tool that analyzes echocardiograms (ultrasound of the heart) to find early signs of four types of heart muscle disease. If the AI flags a high-risk pattern, doctors can learn whether acting on that alert helps catch the condition sooner.
Rochester, MinnesotaAges 18 years+ - NCT07308795Recruiting
Measuring belly breathing muscles in Parkinson’s patients
This trial uses ultrasound to measure the size of belly and rib muscles that help you breathe. It looks at how these muscles relate to the severity of Parkinson’s and your ability to exhale strongly.
Istanbul, BAHÇELİEVLERAges 18–75 - NCT07308808RecruitingEarly Phase 1
Safety of a live bacteria solution for bladder infections
This trial tests if putting a live bacteria called Lactobacillus crispatus into the bladder is safe for people with spinal cord injury and neurogenic lower urinary tract dysfunction. It may help prevent urinary tract infections without antibiotics.
Washington D.C., District of ColumbiaAges 18 years+ - NCT07309107Recruiting
Deep learning study of amyloid pet scans for memory issues
This trial is testing a deep learning tool on amyloid PET scans from patients with memory problems. It aims to improve diagnosis and understanding of Alzheimer's disease.
Vandœuvre-lès-NancyAges 18–99 - NCT07309133Recruiting
Brain signals in dystonia
This trial records brain signals during deep brain stimulation surgery to learn more about dystonia. It may help doctors understand how to improve treatment for people with this condition.
Newcastle upon Tyne, Tyne & WearAges 18 years+ - NCT07309575Recruiting
Hip fracture surgery: regional vs. general anesthesia
This trial compares two types of anesthesia (regional, which numbs just the hip area, vs. general, which puts you fully asleep) to see which one helps with breathing after surgery. It is for patients over 65 having hip fracture surgery.
Lisbon, Lisbon DistrictAges 65 years+ - NCT07309718Recruiting
Stroke Risk Assessment for Brain Artery Narrowing
This study looks at a new way to measure stroke risk in people with a specific type of brain artery narrowing (atherosclerosis) in the front part of the brain. You might participate if you have this condition and are willing to have imaging tests and take standard medicines.
Beijing, Xicheng DistrictAges 18–80 - NCT07310147Recruiting
Online ACT therapy for young-onset Parkinson’s
This trial tests an online program based on Acceptance and Commitment Therapy (ACT) to help people with young-onset Parkinson’s disease cope better with life challenges. It aims to improve emotional well-being and quality of mind.
CoimbraAges 21–65 - NCT07310264RecruitingPhase 1
Safety study of a new drug for Parkinson's disease
This trial tests a new drug called VT-5006 to see if it is safe for people with Parkinson's disease. It focuses on those who have stomach or bowel issues, like constipation.
LeidenAges 18–80 - NCT07310290Recruiting
Study of Ubrogepant for Migraine During the Prodrome Phase
This study looks at how well the migraine medication ubrogepant works when taken during the early signs of a migraine (prodrome). It may help people who already use ubrogepant for their migraines.
Aliso Viejo, CaliforniaAges 18 years+ - NCT07311018Recruiting
Electrical stimulation and motion games for hand function in cerebral palsy
This study tests whether combining electrical stimulation (a gentle muscle zapping) with fun hand exercises using a motion-sensor game can improve hand and wrist movement in children with cerebral palsy. It is designed for children who can move their arms and hands with some difficulty but are not too severely limited.
Istanbul, BeykozAges 6–15
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,487 recruiting neurology studies from the U.S. registry right now, out of 19,851 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.