Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,497 recruiting studies in this area right now.
By phase
- Not applicable9,839
- Phase 2787
- Phase 1573
- Phase 3531
- Phase 4344
- Phase 1/Phase 2304
- Phase 2/Phase 3119
Top conditions
- Stroke856
- Parkinson Disease424
- Alzheimer Disease341
- Multiple Sclerosis341
- Dementia228
- Ischemic Stroke201
- Epilepsy196
- Insomnia156
- Obstructive Sleep Apnea155
- Traumatic Brain Injury154
- Spinal Cord Injuries151
- Sarcopenia149
- Acute Ischemic Stroke141
- Cerebral Palsy129
- Mild Cognitive Impairment128
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital135
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University71
- National Taiwan University Hospital69
- University of Minnesota63
Where studies are running
- California675
- Massachusetts305
- New York294
- Florida277
- Texas270
- Maryland245
- Alabama213
- Arizona211
- Illinois193
- Pennsylvania177
Recruiting studies12,495 total
- NCT01372800Recruiting
Study blood adiponectin levels and stroke/heart risk
This study measures a blood marker called adiponectin and looks at how it relates to heart and stroke (cardiovascular and cerebrovascular) problems over time. It may help doctors understand who is at higher risk, especially in Chinese participants.
Xi'an, ShaanxiAges 18–85 - NCT01772602Recruiting
Join a national ALS patient registry in the U.S.
This study is a national registry that collects information from people with amyotrophic lateral sclerosis (ALS) to better understand the disease. Joining may help researchers learn about patterns of symptoms and care over time.
Atlanta, GeorgiaAges 18 years+ - NCT00874783Recruiting
Testing nerve-cell growth from donated body cells
This trial uses donated body cells or small hair samples from people with neurological diseases (and healthy donors) to try to grow “nerve-like” cells for research. It may help scientists learn how to better study and treat different neurological conditions.
Jerusalem, IsraelAges 18 years+ - NCT00794352Recruiting
Studying immune brain and nerve conditions with tests and samples
This study looks at how immune-related brain or spinal cord illness shows up using exams, MRI scans, and sometimes a spinal fluid test (lumbar puncture), plus collected blood and other samples. It may help researchers better understand these conditions and improve future diagnosis or treatments.
Bethesda, MarylandAges 1 month–99 years - NCT01166854Recruiting
Study of muscle and bone conditions in families
This study looks at how certain muscle and bone diseases show up in people and in their family members. It may help researchers better describe these conditions and improve future diagnosis and care.
Irvine, CaliforniaAges 18 years+ - NCT00801333Recruiting
Create patient-specific stem cells for research
This study uses adult body cells (from participants) to create special lab cells called stem cells for research. It’s mainly about whether cells can be made and studied, not about treating a disease.
JerusalemAges 18 years+ - NCT00857922Recruiting
Neuroscience research repository for brain-related patients
This study collects information and/or tissue for a research library from people who have had neurosurgery and from certain family members. It helps researchers study brain, blood-vessel, injury, tumor, and related conditions.
Houston, TexasAges birth+ - NCT01891318RecruitingPhase 1/Phase 2
Study radiosurgery plus surgery for brain metastases
This trial tests giving focused radiation (radiosurgery) before surgery for certain resectable brain metastases. It may help shrink or control tumors in the brain before they are surgically removed.
Cleveland, OhioAges 18 years+ - NCT02081768RecruitingPhase 3
Yttrium radiation liquid for cyst-like brain tumors near the pituitary
This Phase 3 trial studies a radioactive liquid called yttrium colloid (90Y) given around the time of surgery for cyst-like tumors near the pituitary gland. The goal is to see if it can improve treatment when you need an operation.
Halifax, Nova ScotiaAges 17 years+ - NCT00981396RecruitingEarly Phase 1
EFT therapy to help smokers who struggle to quit
This early-stage study tests Emotional Freedom Techniques (EFT), a gentle talking-and-tapping method, for people who feel very anxious about quitting and still have strong cravings. It may help improve confidence and reduce the emotional triggers that make quitting harder.
Ormskirk, LancashireAges 12–99 - NCT01132885Recruiting
Brain scans in children with Williams syndrome
This study uses brain testing—often MRI scans—to learn how the brains of children with Williams syndrome are different from typical development. It may help researchers better describe brain patterns and improve future care for people with Williams syndrome.
Bethesda, MarylandAges 5 years+ - NCT01829724Recruiting
Brain activity study during repeated movement in some children
This study uses brain and muscle activity recordings while you do simple repeated movements. It may help researchers understand how brains work during movement in people with certain childhood injuries that affect walking and arm/leg control.
Bethesda, MarylandAges 5–100 - NCT01193088Recruiting
Study genetics to find who modifies Charcot-Marie-Tooth (CMT)
This study looks at DNA changes in families with Charcot-Marie-Tooth (CMT), especially a known gene duplication called PMP22. It aims to understand what other genetic factors may change how CMT shows up, which could help future diagnosis and care.
Los Angeles, CaliforniaAges Any age - NCT01950624Recruiting
DS-Connect registry for people with Down syndrome
This is a study registry that collects information from people with Down syndrome (or certain forms like mosaic or partial trisomy 21) and their families. It helps researchers learn about health and needs over time and makes it easier to contact people for future studies.
Aurora, ColoradoAges Any age - NCT01900132Recruiting
Measures nerve and muscle signals in healthy people and patients
This study uses a painless electrical method to record how muscles and nerves work over time. It aims to better understand normal patterns (healthy volunteers) and to learn how these signals change in people with neuromuscular or movement-related conditions.
Bethesda, MarylandAges 2–110 - NCT01276470Recruiting
Study of environmental triggers in anti-synthetase syndrome
This study looks for environmental risk factors that may be linked to anti-synthetase syndrome, a type of inflammatory muscle disease. It compares people with the condition to carefully matched people without it, using questionnaires, blood samples, and lung imaging when needed.
Miami, FloridaAges 2–100 - NCT01906385RecruitingPhase 1/Phase 2
Recurrent brain tumor study testing rhenium nano-liposome
This early-phase study tests a drug made of tiny fat-like particles carrying rhenium for recurrent (coming back) high-grade glioma. It mainly checks safety and the highest tolerable dose, and it also looks for signs the treatment may slow tumor growth.
Manhasset, New YorkAges 18 years+ - NCT01535430Recruiting
Mapping brain function in people with certain brain tumors
This study uses brain “mapping” tests (with MRI and possibly other methods) to identify important brain functions near a tumor. It may help your care team plan a safer surgery by understanding which brain areas do critical tasks.
Omaha, NebraskaAges 19 years+ - NCT01574053Recruiting
Global Huntington’s disease registry for gene carriers and controls
This study builds a global record of people who carry the Huntington’s (HD) gene change and people who do not. By comparing them over time, researchers hope to better understand how HD begins and progresses.
Birmingham, AlabamaAges 18 years+ - NCT01668186Recruiting
Study of how peroxisome disorders change over time
This study follows people with peroxisome biogenesis disorders (PBD) or closely related enzyme/protein defects to learn how symptoms and health changes over time. It may help researchers better understand the condition and plan future treatments.
Montreal, QuebecAges Any age - NCT01732523Recruiting
Check if extra blood-vessel growth predicts stroke risk in carotid narrowing
This study looks at an imaging test to see whether signs of new blood-vessel growth in an artery predict future stroke risk in people who have carotid artery narrowing but no symptoms. If it works, it could help doctors identify who may need closer monitoring or preventive treatment.
BaselAges 18 years+ - NCT01958086Recruiting
Visuomotor prosthetic for people with paralysis
This trial tests a prosthetic device that helps with movement by using brain-and-hand body signals to guide action. You may be able to join if you have paralysis from an injury or illness and can safely have surgery and frequent study visits.
Los Angeles, CaliforniaAges 22–65 - NCT01840930Recruiting
Study of severe cerebral palsy in children
This study looks at children ages 2 to 10 who have severe, long-term cerebral palsy to better understand this condition. It may help clinicians learn what to expect and how to support children with the most significant mobility needs.
BronAges 2–10 - NCT02022943Recruiting
Join an Alzheimer's prevention registry website
This trial builds a registry so researchers can contact you about future Alzheimer’s studies. It mainly requires agreeing to the registry’s website terms and conditions.
Phoenix, ArizonaAges 18–110
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,497 recruiting neurology studies from the U.S. registry right now, out of 19,911 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.