Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,497 recruiting studies in this area right now.
By phase
- Not applicable9,839
- Phase 2787
- Phase 1573
- Phase 3531
- Phase 4344
- Phase 1/Phase 2304
- Phase 2/Phase 3119
Top conditions
- Stroke856
- Parkinson Disease424
- Alzheimer Disease341
- Multiple Sclerosis341
- Dementia228
- Ischemic Stroke201
- Epilepsy196
- Insomnia156
- Obstructive Sleep Apnea155
- Traumatic Brain Injury154
- Spinal Cord Injuries151
- Sarcopenia149
- Acute Ischemic Stroke141
- Cerebral Palsy129
- Mild Cognitive Impairment128
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital135
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University71
- National Taiwan University Hospital69
- University of Minnesota63
Where studies are running
- California675
- Massachusetts305
- New York294
- Florida277
- Texas270
- Maryland245
- Alabama213
- Arizona211
- Illinois193
- Pennsylvania177
Recruiting studies12,495 total
- NCT01964261Recruiting
Study of brain and nerve activity after high neck injury
This study looks at how the brain and nerves change their activity after a high neck (cervical) spinal injury. You may be asked to have imaging—likely an MRI—and to follow daily checks by a caregiver during the study.
Downey, CaliforniaAges 22–65 - NCT02012699Recruiting
Cancer registry for people with or at risk of cancer
This trial collects health information and samples (a “cancer repository”) to help researchers study cancer and cancer risk. You may be able to join if you’ve had cancer before or if you’re at higher risk or have concerning findings.
Greenwood Village, ColoradoAges 19–110 - NCT02081924Recruiting
Testing kisspeptin hormone delivery and blood hormone changes
This study gives the hormone kisspeptin over time and measures how your body’s reproductive hormones respond. It may help researchers understand how reproductive hormone signals work, which could guide future treatments.
LondonAges 18–60 - NCT02098265Recruiting
Brain-signal device for stroke arm rehabilitation
This study tests a device that uses brain activity signals to trigger stroke arm therapy. It may help improve how well your upper arm and hand function by timing the training to your brain’s patterns.
Madison, WisconsinAges 18 years+ - NCT02362685Recruiting
Metabolic exercise testing study
This study is about doing a breathing-and-heart performance test while you exercise to better understand how your body uses energy. You may join if you’re referred for this type of test and can safely complete it.
BrestAges 5 years+ - NCT02435810Recruiting
Study of infections and inflammation affecting the nervous system
This study looks at how infections or inflammation involving the brain and spinal cord work, using patient data and samples. It may help researchers better understand these illnesses and improve future care.
Bethesda, MarylandAges 2–110 - NCT02410850Recruiting
Test how well long-term mouth devices work for sleep apnea
This trial looks at how effective an oral (mouth) appliance is over the long term for people with obstructive sleep apnea. If you already use a mouth device, this study may help doctors understand whether it continues to work well over time.
Vancouver, British ColumbiaAges 18–90 - NCT02433028Recruiting
Long-term study for MS and related nervous system conditions
This is a long-term hospital study that follows people diagnosed with MS (and a few related conditions) to understand how disease changes over time. You may be asked to have regular check-ups, brain scans, and provide blood samples so researchers can track disease and treatment effects.
Aarau, Canton of AargauAges Any age - NCT02714764Recruiting
Testing how best to measure outcomes in Alexander disease
This study is looking at which measurements best capture changes over time in people with Alexander disease. It may help researchers and doctors track the disease more accurately in future care and studies.
Philadelphia, PennsylvaniaAges Any age - NCT02329210Recruiting
Registry study for people with Bardet-Biedl syndrome
This study is a registry that collects health and genetic information from people with Bardet-Biedl syndrome. It may help researchers better understand the condition and improve future care by building a clear group of eligible patients.
Marshfield, WisconsinAges Any age - NCT02635022Recruiting
Care plan plus bone-medicine monitoring after a fracture
This study tests a structured care service to help people manage osteoporosis after a new bone fragility fracture. It aims to improve how you take bone-protecting medicines and to make sure treatment is followed and monitored over time.
HsinchuAges 50 years+ - NCT02407028RecruitingPhase 2
Hyperbaric oxygen treatment for severe traumatic brain injury
This Phase 2 trial studies whether breathing oxygen in a pressurized chamber can improve outcomes after a severe traumatic brain injury. It is mainly for people with very low consciousness levels soon after injury, with careful safety checks.
San Diego, CaliforniaAges 16–65 - NCT02107989Recruiting
MRI and brain scans before epilepsy surgery
This study collects noninvasive brain scan data (mainly MRI, sometimes MEG) from people being evaluated for focal epilepsy surgery, and from healthy volunteers. It aims to build reference “normal” brain images and improve how doctors plan and interpret epilepsy surgery evaluations.
Bethesda, MarylandAges 8–120 - NCT02543424Recruiting
Testing movement and thinking in brain-injury and cerebral palsy
This study looks at how people’s arm/hand movement and attention-thinking skills work after brain injury or cerebral palsy. You might be invited to tasks and simple instructions to help researchers understand function and possible support strategies.
Ottignies, Brabant WallonAges 5 years+ - NCT02440763Recruiting
Study of inherited progressive balance and coordination changes
This is a natural history study that follows people with inherited forms of “ataxia” (problems with balance and coordination) over time. It may help researchers better understand how these conditions progress in daily life and can inform future treatments.
InnsbruckAges 18 years+ - NCT02664831Recruiting
Study of inflammation after cardiac arrest in ICU patients
This trial looks at how the body’s inflammation response behaves after someone has a cardiac arrest and was treated in the ICU. It may help doctors understand which patients could benefit from treatments that target harmful inflammation after resuscitation.
Portland, MaineAges 18 years+ - NCT02216500Recruiting
Study ketogenic diet effects in people with epilepsy
This study looks at how a high-fat, low-carbohydrate ketogenic diet may change electrical activity in the brain and related body measurements in people with epilepsy. You may be asked to follow the diet and keep records so the researchers can compare changes over time.
Gainesville, FloridaAges Up to 50 years - NCT02567136Recruiting
Imaging study for people with ALS using MRI
This trial uses MRI scans to look for “imaging biomarkers” (scan patterns that may help track ALS). It may help researchers better understand disease changes over time and how ALS progresses.
Minneapolis, MinnesotaAges 21–75 - NCT02329652Recruiting
Bionic stimulation to help arm and trunk movement after spinal injury
This study tests a neuroprosthetic system that uses controlled stimulation to help restore movement in the arm and trunk after a spinal cord injury. If you qualify, it may help you regain practical strength and control for everyday tasks.
Cleveland, OhioAges 17 years+ - NCT02784210RecruitingPhase 2
Steroid treatment to reduce inflammation in active MS lesions
This Phase 2 study tests whether corticosteroid medicine can reduce inflammation at the edge of active multiple sclerosis (MS) plaques seen on MRI. It may help calm “hot” areas in the brain where MS activity is happening.
Bethesda, MarylandAges 18–120 - NCT02798705Recruiting
Testing heart tiny blood vessel function in amyloidosis
This study measures how well the heart’s tiny blood vessels work in people with cardiac amyloidosis, using special heart testing. It may help doctors understand the disease better and improve how patients are evaluated over time.
SeoulAges 18–85 - NCT02114450Recruiting
Training with a leg exoskeleton after stroke
This trial tests a “human–machine” leg exoskeleton system to help people with stroke improve standing and walking during rehab. You may be able to participate if you have certain levels of disability and spasticity, can safely stand and walk with help, and don’t have skin, joint, or medical issues that would make training unsafe.
Houston, TexasAges 18–75 - NCT02686125Recruiting
Study of the Vercise brain stimulator for dystonia
This study looks at how well a specific implanted brain stimulator (the Vercise system) works for people with dystonia. It may help confirm whether the device improves symptoms and is safe for eligible patients.
GhentAges 7 years+ - NCT02119611Recruiting
Deep brain stimulation for Parkinson’s, dystonia, or tremor
This study tests deep brain stimulation (DBS), a therapy that sends electrical signals to the brain, for movement problems like Parkinson’s disease, dystonia, and essential tremor. It may help people whose symptoms are not controlled enough with medications, or who already have a DBS device and need ongoing management.
Bethesda, MarylandAges 18–100
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,497 recruiting neurology studies from the U.S. registry right now, out of 19,911 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.