Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,497 recruiting studies in this area right now.
By phase
- Not applicable9,839
- Phase 2787
- Phase 1573
- Phase 3531
- Phase 4344
- Phase 1/Phase 2304
- Phase 2/Phase 3119
Top conditions
- Stroke856
- Parkinson Disease424
- Alzheimer Disease341
- Multiple Sclerosis341
- Dementia228
- Ischemic Stroke201
- Epilepsy196
- Insomnia156
- Obstructive Sleep Apnea155
- Traumatic Brain Injury154
- Spinal Cord Injuries151
- Sarcopenia149
- Acute Ischemic Stroke141
- Cerebral Palsy129
- Mild Cognitive Impairment128
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital135
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University71
- National Taiwan University Hospital69
- University of Minnesota63
Where studies are running
- California675
- Massachusetts305
- New York294
- Florida277
- Texas270
- Maryland245
- Alabama213
- Arizona211
- Illinois193
- Pennsylvania177
Recruiting studies12,495 total
- NCT07477015Recruiting
Study to find new antibodies in autoimmune encephalitis
This research study looks for new markers in the blood of people with autoimmune encephalitis (a condition where the immune system attacks the brain). It aims to better understand what causes the disease and find new ways to diagnose it.
Rome, RMAges 18 years+ - NCT07477119RecruitingPhase 4
Personalized linezolid dosing for drug-resistant TB treatment
This trial tests whether adjusting the dose of linezolid based on regular blood tests can help people with multidrug-resistant tuberculosis (MDR-TB) tolerate the medication better while on the BPaL or BPaL-M regimen. It aims to reduce side effects and improve treatment success.
ConakryAges 15 years+ - NCT07477483Recruiting
Manual therapy for tension headaches in menopausal women
This study tests if manual therapy (gentle hands-on techniques) can help reduce tension-type headaches in women going through menopause or premenopause. It involves tracking your headache symptoms and receiving treatment over several sessions.
Konya, KonyaAges 45–65 - NCT07477509Recruiting
Northwestern neuromuscular disease tissue and blood bank
This study collects tissue and blood samples from people with nerve or muscle disorders to help researchers learn more about these conditions. The goal is to build a bank of samples for future studies.
Chicago, IllinoisAges 18 years+ - NCT07477639RecruitingPhase 1/Phase 2
Testing TRX319 for worsening multiple sclerosis
This trial tests a new treatment called TRX319 for people with progressive multiple sclerosis (MS) that has been getting worse. The study wants to see if this treatment can help slow down disability progression.
Kansas City, KansasAges 18–65 - NCT07477691RecruitingPhase 4
Immune therapy during Palynziq treatment for PKU
This study tests whether combining a drug called methotrexate with Palynziq (a treatment for PKU) can help control immune responses and improve treatment outcomes. It may be an option for adults with PKU who have never used Palynziq or who have not reached target blood levels after at least 24 weeks.
Los Angeles, CaliforniaAges 18–65 - NCT07477821Recruiting
Muscle and brain health study in aging and neurological disorders
This study looks at the link between muscle health and brain function in people with different neurological conditions or healthy aging. It may help researchers understand how muscle changes relate to memory, movement, and thinking problems.
CataniaAges 60 years+ - NCT07478146Recruiting
Aerobic exercise for brain and movement in Parkinson's
This study tests whether moderate aerobic exercise (like brisk walking or cycling) can improve thinking, memory, and walking ability in people with Parkinson's disease. It also looks at how exercise affects blood flow in the brain.
São Paulo, São PauloAges 40 years+ - NCT07478172Recruiting
Electrical muscle stimulation exercise for neuromuscular disease
This study tests whether whole-body electrical muscle stimulation (using small electrodes on the skin) can help adults with certain neuromuscular diseases exercise and improve muscle strength. It may be an option if you can stand for about 15 minutes at a time and have some muscle strength left.
Columbia, MissouriAges 18 years+ - NCT07478367Recruiting
Muscle weakness in hospitalized patients outside the ICU
This study looks at muscle weakness that can develop when you are in the hospital for an acute illness but not in the intensive care unit (ICU). It aims to understand how common this weakness is and what factors might be involved.
RozzanoAges Any age - NCT07478926Recruiting
Testing a skin device to check shunt flow
This study tests a new, noninvasive device placed on the skin over your shunt to see if it can detect when the shunt is open or closed. It may help doctors quickly check if the shunt is working without using X-rays or other procedures.
Peoria, IllinoisAges Any age - NCT07479147Recruiting
Stroke prevention in elderly by PFO closure vs blood thinners
This trial compares two treatments for preventing another stroke in older adults who have a PFO (a small hole in the heart). It tests whether closing the hole with a device works better than using blood-thinning medication.
TaichungAges 18–90 - NCT07479446Recruiting
Comparing two painkillers for nausea after brain surgery
This trial tests if a newer painkiller (oliceridine) causes less nausea after a specific type of brain surgery than the standard painkiller (sufentanil). If you are having CPA region surgery and will receive a patient-controlled pain pump, this study may help find a better option for managing pain with fewer side effects.
BeijingAges 18–65 - NCT07480174Recruiting
Tai Chi and Yoga for Flexibility, Anxiety, and Sleep
This study tests whether gentle exercises like tai chi and yoga can help women feel more flexible, less anxious, and sleep better. If you're a woman between 18 and 45 with no major health problems, you may be able to join.
IstanbulAges 18–45 - NCT07480109Recruiting
More protein while on weight-loss meds in women
This study tests if eating extra protein helps middle-aged women with overweight or obesity who are just starting a GLP-1 medication. You would eat extra protein for a few weeks while staying active as usual.
Austin, TexasAges 30–60 - NCT07481149RecruitingPhase 3
Virtual exercise program for chemo nerve damage
This study tests a virtual exercise program to help people with nerve pain or numbness after chemotherapy. It is designed for anyone who finished chemo at least 6 months ago and still has symptoms in their hands or feet.
Toronto, OntarioAges 18 years+ - NCT07481396Recruiting
Studying brain injury after cardiac arrest through spinal fluid
This trial is looking at the spinal fluid of people who survived a cardiac arrest outside the hospital and are being treated for brain injury. The goal is to learn more about brain damage and find new ways to help patients recover.
Daejeon, Jung-guAges 18 years+ - NCT07481786RecruitingPhase 3
Bevacizumab with focused radiation vs standard brain radiation for lung cancer with brain spread
This trial tests combining a drug called bevacizumab with a focused radiation treatment for people with lung cancer that has spread to the brain. It compares this to the standard radiation approach, and aims to see which better preserves memory and controls tumors.
Chongqing, Chongqing MunicipalityAges 18 years+ - NCT07482072Recruiting
Brain blood flow and sugar study for Alzheimer's and diabetes
This study uses brain scans to see how blood flow and sugar transport work in people with both Alzheimer's disease and type 2 diabetes. It may help doctors understand how these conditions interact and find better treatments.
HerlevAges 60–90 - NCT07482124Recruiting
Registry study for patients with subarachnoid hemorrhage
This study collects information on people who have had a subarachnoid hemorrhage (a type of brain bleed) from certain causes. It helps doctors better understand the condition and improve care.
Nijmegen, GelderlandAges Any age - NCT07482462Recruiting
Blood pressure and heart rate study in healthy and hypertensive adults
This trial looks at how blood pressure and heart rate change when standing up or exercising in healthy people and in older adults with high blood pressure. It aims to understand how the body's automatic (autonomic) nervous system controls these functions.
LjubljanaAges 18 years+ - NCT07482501Recruiting
Magnetic brain stimulation for heart health after stroke
This study uses repetitive transcranial magnetic stimulation (a non-invasive brain treatment using magnetic pulses) to improve heart rate control in people who have had a stroke. It may help your body better manage stress and blood pressure.
AfyonkarahisarAges 35–80 - NCT07482579Recruiting
Stroke Recovery Prediction Using a Digital Twin
This study uses digital twin technology to predict how well people will recover after a stroke. It looks at your walking ability and other factors to create a personalized recovery plan.
Gyeonggi-do, Gyeonggi-doAges 20 years+ - NCT07482800Recruiting
Dementia in stories and real-life medical cases
This study looks at how people with early Alzheimer's or mild memory problems understand stories compared to healthy adults. Your participation could help researchers learn more about how dementia affects thinking and language.
New Taipei CityAges 60–85
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,497 recruiting neurology studies from the U.S. registry right now, out of 19,911 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.