Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,504 recruiting studies in this area right now.
By phase
- Not applicable9,843
- Phase 2785
- Phase 1574
- Phase 3532
- Phase 4345
- Phase 1/Phase 2306
- Phase 2/Phase 3119
Top conditions
- Stroke852
- Parkinson Disease423
- Alzheimer Disease342
- Multiple Sclerosis339
- Dementia229
- Ischemic Stroke201
- Epilepsy196
- Insomnia156
- Obstructive Sleep Apnea156
- Traumatic Brain Injury155
- Spinal Cord Injuries151
- Sarcopenia150
- Acute Ischemic Stroke142
- Cerebral Palsy129
- Mild Cognitive Impairment128
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis106
Leading sponsors
- Beijing Tiantan Hospital135
- Riphah International University127
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University71
- National Taiwan University Hospital69
- University of Minnesota64
Where studies are running
- California677
- Massachusetts308
- New York294
- Florida278
- Texas270
- Maryland245
- Alabama214
- Arizona210
- Illinois193
- Pennsylvania177
Recruiting studies12,502 total
- NCT07579481Recruiting
Vortioxetine for Depression with Migraine
This study tests whether vortioxetine, a depression medication, can help people who have both depression and episodic migraine (recurring headaches). You'd take vortioxetine for depression while researchers track how it affects both your mood and migraine symptoms.
Rome, LazioAges 18 years+ - NCT07579559Recruiting
Animal Fun Program for Movement Development in Down Syndrome
This study tests whether a fun program involving animals helps children with Down syndrome improve their movement and physical skills. Researchers will work with children aged 6–9 to see if this approach strengthens balance, coordination, and overall mobility.
Lahore, Punjab ProvinceAges 6–9 - NCT07579871Recruiting
Sleep patterns and recovery after first stroke
This study looks at how sleep affects recovery in people who have had their first ischemic stroke (a stroke caused by a blood clot). Researchers want to understand whether sleep quality influences how well patients regain function after stroke.
Lund, Skåne CountyAges 18 years+ - NCT07580183Recruiting
Memory and Brain Function in Epilepsy Surgery
This study examines how the brain recognizes spatial scenes (like rooms or landscapes) in people with epilepsy who may have surgery. Researchers want to understand memory patterns before and after surgery to help predict outcomes.
Sacramento, CaliforniaAges 18–55 - NCT07580612Recruiting
Home-based AI system for detecting freezing of gait in Parkinson's
This study tests an artificial intelligence system that detects freezing of gait—sudden, involuntary pauses while walking—using sensors you wear at home. The goal is to better understand and eventually help manage this common Parkinson's symptom.
LeuvenAges 18 years+ - NCT07580703RecruitingPhase 1
Brain Imaging Study for Memory and Thinking Changes
This study tests a new type of brain scan (called [18F]Flortaucipir PET) that may help detect early signs of Alzheimer's disease. Researchers want to make sure the scan is safe and works well in Chinese patients aged 50–85 with normal thinking, mild memory problems, or Alzheimer's disease.
Beijing, Beijing MunicipalityAges 50–85 - NCT07580820Recruiting
Walking Adaptability in Early-Stage Multiple Sclerosis
This study looks at how people with mild multiple sclerosis (MS) adapt their walking and balance. Researchers will test your walking ability and how your body adjusts to different movements, which could help improve care for people with MS.
DiepenbeekAges 18–65 - NCT07581210RecruitingPhase 2
QD202 Study for Recent Stroke Treated With Clot-Busting Medicine
This study tests whether a new drug called QD202 can help protect the brain and improve recovery when given alongside standard clot-busting therapy (thrombolysis) for acute ischemic stroke. You would be in the trial if you had a stroke in the last 24 hours and are receiving or planning to receive thrombolytic treatment.
Meizhou, GuangdongAges 18–85 - NCT07581938Recruiting
Early Dental Screening for Sleep Problems in Kids
This study uses a smartphone app and a wearable device to check for early signs of sleep-disordered breathing—a condition where breathing stops briefly during sleep—in children ages 8–13. The goal is to catch dental and jaw problems that might lead to sleep issues before they become serious.
Chapel Hill, North CarolinaAges 8–13 - NCT07582744Recruiting
Imaging tests for spontaneous spinal fluid leaks
This study compares two specialized imaging techniques to help diagnose spontaneous spinal fluid leaks (a rare condition causing severe headaches). The goal is to improve how doctors identify where the leak is coming from so patients can get the right treatment.
Durham, North CarolinaAges 18 years+ - NCT07583498Recruiting
Treating Muscle Stiffness After Spinal Cord Injury With Oxygen Therapy
This study tests whether brief periods of low oxygen (called acute intermittent hypoxia) can reduce muscle stiffness and tightness that develops after a spinal cord injury. Researchers believe this approach may help improve arm and hand function.
Chicago, IllinoisAges 18 years+ - NCT07583823Recruiting
Higher-Rate Pacing for Heart Amyloid Disease
This study tests whether pacing your heart at a faster rate helps people with cardiac amyloidosis (a condition where abnormal protein builds up in the heart). If you have a pacemaker and cardiac amyloidosis, this research might help doctors understand the best pacing settings for you.
Minneapolis, MinnesotaAges 18 years+ - NCT07584525RecruitingPhase 3
Dexamethasone treatment for tick-borne encephalitis
This study tests whether a steroid medication called dexamethasone can help people with tick-borne encephalitis, a serious brain infection spread by ticks. The goal is to see if this treatment reduces inflammation in the brain and improves recovery.
LjubljanaAges 18 years+ - NCT07585045Recruiting
Magnesium Supplements for Fibromyalgia Not Helped by Standard Drugs
This study tests whether taking magnesium by mouth can reduce fibromyalgia pain in people whose symptoms don't improve with common medications like amitriptyline, duloxetine, or pregabalin. Magnesium is a mineral that may help relax muscles and ease pain.
Lahore, Punjab ProvinceAges 18–65 - NCT07585409Recruiting
Physical Activity for Parkinson's Disease Patients
This study tests whether physical activity (like exercise or movement) can help people with Parkinson's disease feel better and move more easily. Researchers want to understand how activity affects Parkinson's symptoms and quality of life.
StockholmAges 18 years+ - NCT07588178Recruiting
Sleep Problems Before Heart Surgery: Study on Recovery
This research examines how sleep issues before heart surgery may affect how well patients recover afterward. Researchers will study blood markers and chemical changes to better understand this connection and potentially improve surgical outcomes.
Beijing, Beijing MunicipalityAges 18–80 - NCT07588503RecruitingPhase 1
FES Cycling With Blood Flow Restriction for Spinal Cord Injury
This study tests a new exercise method combining electrical stimulation (FES) and controlled blood flow restriction while you cycle. It's designed to improve heart health, blood sugar control, and fitness in people with spinal cord injuries.
Toronto, OntarioAges 18–75 - NCT07588971Recruiting
Understanding childhood epilepsy outcomes and long-term patterns
This study tracks children with epilepsy to understand how different types progress over time and what factors affect their outcomes. By learning more about your child's epilepsy journey, researchers hope to improve how doctors predict and manage the condition.
RomeAges Up to 18 years - NCT07588997Recruiting
Brain Training After Aneurysm Bleeding to Improve Thinking and Movement
This study tests whether combining thinking exercises with physical movements can help people recover better after a brain aneurysm ruptures and bleeds. You'd start the training early in your recovery (2-7 days after treatment) to see if it helps your memory, attention, and ability to move.
TaipeiAges 18 years+ - NCT07589257RecruitingPhase 2
VRT106 drug combined with radiation for brain stem tumors
This trial tests whether a new drug called VRT106, given alongside radiation therapy, can help treat a serious type of brain tumor called diffuse midline glioma or DIPG. The drug is designed to work with radiation to fight the cancer.
Guangzhou, GuangdongAges 18–75 - NCT07589296Recruiting
Robot-Assisted Walking vs. Electrical Stimulation for Parkinson's
This study compares two ways to help people with Parkinson's disease improve their walking: using a robotic device to guide your legs, or electrical stimulation (mild electrical pulses to leg muscles). The goal is to see which approach helps you walk better and more confidently.
Küçükçekmece, IstanbulAges 40–80 - NCT07589790Recruiting
Virtual Reality and Mindfulness for Chronic Low Back Pain
This study tests whether virtual reality combined with mindfulness-based cognitive therapy can help reduce chronic low back pain lasting 3+ months. The trial aims to see if this newer approach eases pain and improves quality of life.
Suzhou, JiangsuAges 20–70 - NCT07589855Recruiting
Touch therapy for neglect awareness after stroke
This study tests whether regular touch-based therapy can help stroke survivors who ignore one side of their body (called unilateral neglect). You would receive therapy sessions, likely at home, to see if this treatment improves your awareness and function.
Newcastle-under-LymeAges 18 years+ - NCT07591272Recruiting
Dance therapy to help people recover from stroke
This study tests whether adaptive dance activities can help people in early stroke recovery regain movement and function. You would participate in dance-based exercises during your hospital stay as part of your stroke care.
Hong KongAges 18–80
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,504 recruiting neurology studies from the U.S. registry right now, out of 19,972 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.