Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,504 recruiting studies in this area right now.
By phase
- Not applicable9,843
- Phase 2785
- Phase 1574
- Phase 3532
- Phase 4345
- Phase 1/Phase 2306
- Phase 2/Phase 3119
Top conditions
- Stroke852
- Parkinson Disease423
- Alzheimer Disease342
- Multiple Sclerosis339
- Dementia229
- Ischemic Stroke201
- Epilepsy196
- Insomnia156
- Obstructive Sleep Apnea156
- Traumatic Brain Injury155
- Spinal Cord Injuries151
- Sarcopenia150
- Acute Ischemic Stroke142
- Cerebral Palsy129
- Mild Cognitive Impairment128
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis106
Leading sponsors
- Beijing Tiantan Hospital135
- Riphah International University127
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University71
- National Taiwan University Hospital69
- University of Minnesota64
Where studies are running
- California677
- Massachusetts308
- New York294
- Florida278
- Texas270
- Maryland245
- Alabama214
- Arizona210
- Illinois193
- Pennsylvania177
Recruiting studies12,502 total
- NCT07601841Recruiting
Light therapy to improve sleep after brain injury
This study tests whether light therapy can help people sleep better after a traumatic brain injury (TBI). Researchers will use MRI brain scans and sleep tracking to see if light therapy changes how your brain clears toxins during sleep.
Portland, OregonAges 18–89 - NCT07602595Recruiting
Understanding pain after childhood rheumatic disease or surgery
This study helps researchers learn how young adults (ages 14–26) who had rheumatic disease or orthopedic surgery as children experience pain over time. By understanding your story, the study may help doctors better support others facing similar challenges.
Cincinnati, OhioAges 14–26 - NCT07603102Recruiting
Mindfulness and Walking Training for Memory After Stroke
This study tests whether combining mindfulness meditation with balance and walking exercises can help improve memory and thinking skills in people who had a stroke. The trial focuses on people with mild cognitive impairment—difficulty thinking clearly—after stroke recovery.
NanjingAges 55 years+ - NCT07603323Recruiting
Pain Relief Methods for Meniscus Knee Surgery
This study compares two different numbing techniques (ACB and ACB combined with BiFeS) to see which one better controls pain after meniscus surgery. The meniscus is cartilage in your knee that can tear and cause pain.
AnkaraAges 18–65 - NCT07603583Recruiting
Heart Rate Variability to Detect Sleep Apnea in Hypertension
This study tests whether a simple heart-rate measurement can help detect obstructive sleep apnea (a breathing condition during sleep) in people with high blood pressure. The goal is to find an easier way to screen for sleep apnea, which often goes undiagnosed but can worsen heart health.
Kaohsiung City, KaohsiungAges 18–65 - NCT07603752Recruiting
Brain implant to restore arm movement in spinal cord injury
This trial tests a wireless implant placed on the brain's surface to help people with cervical (neck-level) spinal cord injuries regain some arm and hand movement. The device reads brain signals and sends them to muscles, potentially bypassing the damaged spinal cord.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT07603804Recruiting
Accelerated Brain Stimulation for Treatment-Resistant Depression
This study tests an accelerated form of iTBS (a non-invasive brain stimulation technique) for depression that hasn't improved with antidepressant medications. The goal is to help people with major depression who haven't responded adequately to at least one antidepressant drug.
IstanbulAges 18–65 - NCT07603973Recruiting
Smartphone App to Help Manage Knee Osteoarthritis
This study tests whether a smartphone app that provides information and self-management tools helps people with knee osteoarthritis feel better and manage their condition. You would use the app at home to learn exercises, track symptoms, and get support.
Oslo, OsloAges 50 years+ - NCT07604181Recruiting
Telerehabilitation vs clinic therapy for stroke arm recovery
This trial compares two ways of helping stroke survivors regain arm and hand function: therapy done remotely online versus in-person at a clinic. Both use a specialized approach called constraint-induced movement therapy, which encourages use of the weaker arm. The study aims to see which method works better for people in the first 6 months after stroke.
Faisalabad, Punjab ProvinceAges 40–70 - NCT07604896RecruitingPhase 4
Lecanemab for early Alzheimer's disease with amyloid buildup
This trial tests lecanemab, an infusion medicine that targets amyloid protein buildup in the brain, in people with mild cognitive impairment or mild Alzheimer's disease. Researchers will track how well it works and study how it affects your body's proteins using advanced lab tests.
Wenzhou, ZhejiangAges 50–90 - NCT07605858Recruiting
Epilepsy, Sleep, and Brain Activity Study
This study examines how seizures affect sleep quality and dreams in people with hard-to-treat focal epilepsy. Researchers will use specialized brain electrodes to understand these connections during sleep, which may help improve treatment in the future.
Durham, North CarolinaAges 18–55 - NCT07606300Recruiting
Light Training to Help Light Sensitivity After Head Injury
This trial tests whether a training program using colored light targets can help reduce light sensitivity (photophobia) that some people experience after a traumatic brain injury. The training involves focusing your eyes on lights during several visits.
Columbus, OhioAges 18–80 - NCT07606547Recruiting
Swallowing Strength Training for Parkinson's Disease
This study tests whether a mouth and throat muscle-strengthening device called EMST helps people with Parkinson's disease who have difficulty swallowing. Stronger throat muscles may make swallowing safer and easier.
MünsterAges 18 years+ - NCT07606794Recruiting
Hip Surgery Pain Relief Using Nerve Blocks
This study tests two types of nerve-blocking injections to reduce pain after hip replacement surgery. The injections numb specific nerves around your hip so you need less pain medication after the operation.
Tanta, El-GharbiaAges 18–75 - NCT07606807RecruitingPhase 3
New clot-busting medication for stroke in the extended time window
This trial tests a new medication called rhTNK-tPA for treating acute ischemic stroke (a clot in the brain) up to 24 hours after symptom onset. The study uses simplified imaging to determine eligibility and aims to help patients recover better outcomes.
GuangzhouAges 18 years+ - NCT07608432RecruitingPhase 3
Testing a New DMD Treatment Given Every 4 Weeks
This study tests whether a new medicine called zeleciment rostudirsen can help ambulatory (walking) males with Duchenne muscular dystrophy (DMD). The medicine is given as an intravenous infusion (through a vein) every 4 weeks and works by helping the body produce a protective muscle protein.
Hillsborough, North CarolinaAges 4–18 - NCT07608588Recruiting
Brain Stimulation for Language Recovery After Stroke
This study tests whether a non-invasive brain stimulation technique called rTMS can help people regain language skills after a left-sided stroke, particularly for word-finding and meaning difficulties. Researchers will target specific brain regions to see if stimulation improves recovery.
Columbia, South CarolinaAges 18 years+ - NCT07609316Recruiting
Online Support Program for Dementia Family Caregivers
This study tests an online education program designed to help family members who care for someone with dementia. The program teaches coping strategies and provides emotional support to reduce caregiver stress and improve well-being.
Daejeon, Jung-gu, DaejeonAges 19 years+ - NCT07609329Recruiting
Nutritional Support Before Sarcoma Surgery
This study tests whether special nutritional supplements given before surgery for bone or soft tissue sarcoma (a type of cancer) can help your body heal better and recover faster. You'll take oral supplements for at least a week before your planned surgery.
BrnoAges Any age - NCT07609394Recruiting
Duchenne and Becker Muscular Dystrophy Health Records Study
This study collects electronic health records (medical information already in your doctor's computer system) from people with Duchenne or Becker muscular dystrophy, or female carriers of these conditions. Researchers will use this data to better understand the diseases and improve care over time.
Little Rock, ArkansasAges Any age - NCT07609407Recruiting
Pelvic Stability Training After Stroke for Leg Function
This study tests whether special exercises focused on stabilizing your pelvis (hip area) can help improve leg strength and movement after a stroke. The training is designed for people in the early recovery phase who are learning to stand and walk again.
Faisalabad, Punjab ProvinceAges 40–60 - NCT07609433Recruiting
Reducing Heat and Air Pollution Exposure in Pregnant Women
This study helps pregnant women in their second trimester reduce exposure to heat and air pollution through monitoring and personalized advice. Researchers want to see if reducing these environmental stressors improves pregnancy health outcomes.
LimassolAges 20–35 - NCT07609966Recruiting
Virtual Reality for Stroke Arm Recovery
This trial tests whether virtual reality exercises help stroke patients recover arm and hand movement faster and better. You'd use VR games alongside your regular rehabilitation therapy in the hospital and after going home.
GironaAges 18 years+ - NCT07610031Recruiting
Trunk Exercises and Mirror Therapy for Balance in Parkinson's
This study tests whether specific exercises for your trunk (torso) combined with mirror therapy can help improve balance and posture in people with Parkinson's disease. These techniques may help you move more safely and reduce fall risk.
Lahore, Punjab ProvinceAges 50–70
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,504 recruiting neurology studies from the U.S. registry right now, out of 19,972 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.