Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,516 recruiting studies in this area right now.
By phase
- Not applicable9,855
- Phase 2786
- Phase 1573
- Phase 3533
- Phase 4344
- Phase 1/Phase 2305
- Phase 2/Phase 3120
Top conditions
- Stroke852
- Parkinson Disease423
- Alzheimer Disease341
- Multiple Sclerosis340
- Dementia230
- Ischemic Stroke202
- Epilepsy197
- Insomnia156
- Obstructive Sleep Apnea156
- Traumatic Brain Injury156
- Spinal Cord Injuries152
- Sarcopenia151
- Acute Ischemic Stroke141
- Cerebral Palsy129
- Mild Cognitive Impairment128
- Migraine112
- Pain Management112
- Amyotrophic Lateral Sclerosis106
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University127
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon80
- Johns Hopkins University71
- National Taiwan University Hospital71
- University of Minnesota65
Where studies are running
- California678
- Massachusetts307
- New York295
- Florida274
- Texas271
- Maryland245
- Alabama214
- Arizona209
- Illinois193
- Pennsylvania177
Recruiting studies12,514 total
- NCT05921240Enrolling by invitation
Study on access to vision care for young people with vision needs
This study looks at what gets in the way of getting vision services for children and teens with special vision needs. It will help identify barriers and solutions by using questionnaires and interviews in Chinese.
TaipeiAges 19–99 - NCT05919160Enrolling by invitation
New tiny electrode to record brain activity during DBS
This study tests a high-density microelectrode that captures detailed brain recordings while surgeons place a deep brain stimulator for Parkinson’s disease. It may help doctors better locate the exact brain area to target during surgery.
Los Angeles, CaliforniaAges 18 years+ - NCT05911139Enrolling by invitation
Study how anesthesia affects brain injury markers in craniosynostosis surgery
This study looks at how general anesthesia may affect “brain injury marker” levels during and after surgery for single-suture craniosynostosis in infants. It may help doctors better understand anesthesia timing and safety for babies having corrective surgery.
BratislavaAges Up to 18 years - NCT05901233Enrolling by invitation
Remote brain stimulation and speech therapy for primary progressive aphasia
This study tests whether combining speech-language treatment with remotely supervised brain stimulation (a mild current to the scalp) can improve communication in people with primary progressive aphasia. You and a study partner would also join online training and regular video check-ins.
San Francisco, CaliforniaAges Any age - NCT05897957Enrolling by invitation
Follow-up study for people who received BRT-DA01
This study is for people with Parkinson’s disease who previously took part in an earlier BRT-DA01 trial and finished it (or stopped it). It mainly checks how participants do over time after that earlier treatment.
Orange, CaliforniaAges 50–78 - NCT05876910Enrolling by invitation
Study brain signals for stopping speech during epilepsy care
This study looks at how the brain helps stop ongoing speech. It may help researchers understand brain control during medication-resistant epilepsy surgery, using recordings from implanted electrodes.
San Francisco, CaliforniaAges 18–65 - NCT05870527Enrolling by invitation
Pupil changes during vagus nerve stimulation during ear surgery
This study looks at how your pupils (the black center of the eye) respond while a vagus nerve device is turned on during surgery for either a cochlear implant or a vagus nerve stimulator. It aims to better understand the eye/nerve effects of this stimulation, which may improve how such procedures are done safely.
New York, New YorkAges 18 years+ - NCT05863897Enrolling by invitation
Online program to help long-term fatigue after brain injury
This trial tests an online, blended coaching program for severe fatigue that lasts at least 6 months after a stroke or traumatic brain injury. It may help reduce fatigue by supporting self-management using an internet-based approach.
Wijk aan Zee, North HollandAges 18–70 - NCT05859997Enrolling by invitation
CAR-T cell therapy for active autoimmune disease flare-ups
This study tests an immune-cell treatment (CAR-T, called BRL-301) in people with certain autoimmune diseases that are active and hard to control. It may help your immune system calm down if standard treatments have not worked or your disease has returned.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT05859568Enrolling by invitation
Hearing device fit checks and baseline performance study
This study measures how well hearing devices work and how they are best fitted at the start. It helps the company collect baseline information so future testing and fitting can be improved.
Valencia, CaliforniaAges 8 years+ - NCT05848778Enrolling by invitation
Noninvasive treatment aimed at nerve regrowth in the hand
This trial tests a non-surgical therapy to help regrow damaged hand nerves and improve symptoms like numbness, pain, and hand weakness. It may be most helpful if your nerve damage affects sleep and hand dexterity.
Edmonton, AlbertaAges 18–60 - NCT05834829Enrolling by invitation
Ultrasound scan to study the body’s automatic (stress) responses
This trial tests a low-intensity ultrasound approach while measuring how your nervous system and body respond automatically (like changes in heart rate or stress signals). It may help researchers learn how to stimulate or monitor these responses safely, using imaging and standard monitoring.
Roanoke, VirginiaAges 18–65 - NCT05831839Enrolling by invitation
Computer training for attention and memory after COVID
This study tests whether computer-based exercises can improve attention and working memory in adults who still have cognitive (thinking) complaints after COVID. It may help if your focus and memory issues have lasted for a while.
Rotterdam, South HollandAges 18 years+ - NCT05826912Enrolling by invitationPhase 2
Testing new treatment for acute brain injury after a fall or hit
This study tests an investigational treatment to improve outcomes after a recent non-penetrating traumatic brain injury (like a fall or car crash). It uses early CT/MRI imaging and a blood test soon after injury to see who benefits and how well the treatment works.
San Francisco, CaliforniaAges 18–65 - NCT05826457Enrolling by invitation
Study for early RBD as a possible Parkinson’s risk
This study looks at people with REM sleep behavior disorder (RBD), confirmed by a sleep test, who may be in the early “prodromal” stage before Parkinson’s or related diseases. It also enrolls healthy controls to compare results from brain and body testing to better understand who is at risk.
Los Angeles, CaliforniaAges 18 years+ - NCT05814991Enrolling by invitation
Study of factors affecting operating field visibility in jaw surgery
This study looks at what makes the surgeon’s view during jaw (orthognathic) surgery better or worse. It aims to identify predictors that could improve safety and surgical conditions for patients undergoing bimaxillary osteotomy.
MoscowAges 18–40 - NCT05812092Enrolling by invitation
Surgery for one or two levels of neck disc degeneration
This trial studies whether an operation to remove and decompress damaged neck discs (and fuse the area) helps people with painful nerve problems in the neck/arm. It’s meant for cases where non-surgery treatments haven’t worked and imaging shows the problem matches your symptoms.
Fort Worth, TexasAges 18 years+ - NCT05810428Enrolling by invitation
Using AI to predict outcomes and test pain treatment for trigeminal neuralgia
This study uses computer-based (AI) predictions to better understand what happens after a specific procedure for trigeminal neuralgia, a face pain condition. It also checks how well a “pain neuromodulation” approach works and what it feels like over time.
MilanAges 18 years+ - NCT05805839Enrolling by invitationPhase 2
Study uses brain scans to understand demyelinating diseases
This trial compares scan results in people with multiple sclerosis or related demyelinating conditions versus people without inflammatory demyelinating diseases. The goal is to better understand what’s happening in the brain and how sex differences may play a role.
Rochester, MinnesotaAges 18 years+ - NCT05796440Enrolling by invitationPhase 2
Long-term safety study of LUM-201 in children with growth hormone deficiency
This trial checks the long-term safety of LUM-201 in children who have idiopathic growth hormone deficiency and already completed an earlier LUM-201 study. If you previously took LUM-201 and are allowed to continue, the study may help your care team monitor ongoing effects over time.
Iowa City, IowaAges 5–14 - NCT05786729Enrolling by invitationPhase 1/Phase 2
Aerobic exercise program after traumatic brain injury
This trial tests whether a supervised aerobic exercise plan is safe and helpful for people recovering from traumatic brain injury (TBI). It may help improve physical fitness and functioning through regular walking and aerobic training.
Bakersfield, CaliforniaAges 18–60 - NCT05779475Enrolling by invitation
Study of people with moderate Parkinson’s disease
This is an observational study, meaning it doesn’t test a new drug—researchers mainly follow people to better understand moderate Parkinson’s disease and who may be good candidates for future cell therapy. If you have moderate symptoms that aren’t well controlled with tablets, this study may help inform better future treatments.
Irvine, CaliforniaAges 50–68 - NCT05772468Enrolling by invitation
Virtual pain care for people getting wound treatment
This trial tests a virtual (VR) pain-care approach during wound care procedures. It may help reduce how painful the treatments feel, especially for people who have had very painful wound care before.
Amsterdam, North HollandAges 18 years+ - NCT05762055Enrolling by invitation
Compare two neck fusion methods for arthritis pain
This study compares two ways of doing neck fusion surgery for people with age-related (degenerative) problems in the cervical spine. It may help surgeons learn which method works best for healing and long-term outcomes.
Dallas, TexasAges 18–99
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,516 recruiting neurology studies from the U.S. registry right now, out of 20,061 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.