Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,406 recruiting studies in this area right now.
By phase
- Not applicable9,740
- Phase 2783
- Phase 1576
- Phase 3534
- Phase 4342
- Phase 1/Phase 2307
- Phase 2/Phase 3124
Top conditions
- Stroke841
- Parkinson Disease427
- Alzheimer Disease342
- Multiple Sclerosis341
- Dementia227
- Ischemic Stroke201
- Epilepsy197
- Obstructive Sleep Apnea156
- Insomnia154
- Spinal Cord Injuries153
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke138
- Cerebral Palsy131
- Mild Cognitive Impairment130
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California681
- Massachusetts299
- New York292
- Florida275
- Texas265
- Maryland246
- Arizona212
- Alabama210
- Illinois188
- Pennsylvania177
Recruiting studies12,404 total
- NCT07200518Recruiting
Probiotics after spine surgery study
This trial tests if taking probiotics after spinal surgery helps recovery. It is for adults with a herniated disc, spinal narrowing, or instability in the lower back or neck.
MariborAges 18 years+ - NCT07242300RecruitingPhase 3
Testing a new botulinum toxin for arm stiffness after stroke
This trial tests a new injectable medication (Eveotox) to see if it can safely reduce arm or hand stiffness in people who have had a stroke. The goal is to improve daily activities like dressing or cleaning your hand.
Beijing, Beijing MunicipalityAges 18–80 - NCT07205666Recruiting
Eplontersen pregnancy and breastfeeding safety study
This study tracks the safety of eplontersen during pregnancy and breastfeeding by collecting reports from people who have taken it. It helps doctors understand any risks to the baby or mother.
FrankfurtAges Any age - NCT07267403Recruiting
Brain activity and sedation during anesthesia
This trial studies how stimulating a nerve in the wrist affects brain activity and sedation levels during propofol anesthesia. It may help improve care for right-handed patients having surgery.
BrusselsAges 18–81 - NCT07222826Recruiting
Noninvasive Brain Pressure Test Using Ultrasound
This study tests a new way to estimate pressure inside the skull without extra needles or surgery. It uses a soft mask and ultrasound to measure pressure at a vein near the eye, aiming to find a safer alternative for people who already have a standard brain-pressure monitor in place.
Houston, TexasAges 18 years+ - NCT07250893Recruiting
Resolving early life stress in depression: a psychotherapy study
This trial tests if a specific type of psychotherapy can help people with moderate-to-severe depression who experienced stress or adversity in childhood (before age 18). Researchers want to see how the treatment works in the brain and whether it improves depression symptoms.
Hamilton, OntarioAges 18–65 - NCT07128706Enrolling by invitation
Making youth football safer from concussions in Europe
This trial tests whether putting new concussion safety guidelines into practice in youth football clubs across Europe can help protect young players. It looks at how coaches, players, parents, referees, and medical staff can work together to make the sport safer.
Istanbul, IstanbulAges Any age - NCT07130669RecruitingPhase 1/Phase 2
Memory and thinking study for older adults
This trial tests a program to help maintain or improve memory and thinking skills in older adults. You may join if you are 60-89, speak English, and live at home or in an assisted-living facility.
Palo Alto, CaliforniaAges 60–89 - NCT07173153Enrolling by invitationPhase 1/Phase 2
Gene therapy study for SLC6A1 genetic disorder
This trial tests a gene therapy for people with a specific mutation (S295L) in the SLC6A1 gene, which causes a neurodevelopmental disorder. The therapy aims to correct the genetic issue, and participants will be monitored closely for safety and effectiveness.
Columbus, OhioAges Any age - NCT07129603Recruiting
Detecting Brain Complications After a Non-Traumatic Bleed
This study looks for clues in your blood or spinal fluid that might predict brain spasms, delayed damage, or infections after a brain bleed. If you already need a drain to remove fluid, you could be a candidate.
DebrecenAges 18 years+ - NCT07179887Recruiting
Arm cuff treatment for better brain blood flow in older adults
This trial tests if a simple, at-home arm cuff treatment (Remote Ischaemic Conditioning) can improve blood flow regulation in the brain of older adults. It may help understand how to protect brain health as we age.
Derby, DerbyshireAges 65–85 - NCT07110688Recruiting
Brain sensing study for mental states
This trial uses sensors and machine learning to understand mental states in healthy adults and people with epilepsy. Researchers aim to improve how we monitor and support mental health.
Downey, CaliforniaAges 18 years+ - NCT07160413Recruiting
Peripheral nerve sensitivity test in healthy adults
This study tests how sensitive healthy people's nerves are to mild electrical stimulation on the arm. It aims to understand normal nerve response and could help improve treatments for nerve-related conditions.
Biel, BielAges 18 years+ - NCT07157839Recruiting
Tau Levels in Donated Blood
This study measures a substance called tau in blood plasma from donors to help researchers understand brain health. If you've donated plasma, your sample may be used.
Houston, TexasAges Any age - NCT07135050RecruitingPhase 1/Phase 2
Gene therapy study for Pitt Hopkins syndrome
This trial tests a new gene therapy called MZ-1866 for people with Pitt Hopkins syndrome. The therapy is given as a single injection into the fluid around the brain to help replace the missing or faulty TCF4 gene.
Oakland, CaliforniaAges 2–25 - NCT07156214Recruiting
Understanding RFC1-ataxia to find biomarkers
This study looks at a rare genetic condition called RFC1-ataxia (also known as CANVAS). It aims to find better ways to diagnose and track the disease. You may qualify if you have this condition, are between 18 and 80, and can agree to take part.
BolognaAges 18–80 - NCT07087574Recruiting
Study of 3D printed tools for eating independence in rehab
This study tests whether using 3D printed tools can help people with neurodegenerative diseases eat more independently during their hospital stay. It focuses on patients who already need some help with meals, and aims to see if custom-made utensils or aids can give them more autonomy.
Hyères, VarAges 18 years+ - NCT07045259Recruiting
Exergaming vs. exercise for memory and movement in seniors
This study compares fun video games that get you moving (exergaming) with standard muscle-strengthening exercises. It aims to see which one better helps older adults who have both slower walking speed and memory concerns.
BalıkesirAges 65 years+ - NCT07058428RecruitingPhase 3
FSRT with Avastin for multiple brain tumors from lung cancer
This trial tests giving focused radiation (FSRT) along with Avastin (bevacizumab) to people with multiple brain metastases from lung adenocarcinoma. It aims to see if combining these treatments is safe and effective for tumors that are too large or numerous for standard one-time radiation.
Guangzhou, GuangdongAges 18 years+ - NCT06259071Recruiting
Saliva study for MuSK myasthenia gravis
This study gathers saliva samples from people with MuSK myasthenia gravis to better understand the condition. Participation involves providing a saliva sample and sharing your lab results.
Washington D.C., District of ColumbiaAges 7–99 - NCT07615400Recruiting
Long-term study of people with fucosidosis
This study follows people with fucosidosis over time to learn more about how the condition progresses. It is an observational study, so participants do not receive any new treatment—just regular health monitoring to help researchers better understand the disease.
Orange, CaliforniaAges Any age - NCT07747974Recruiting
Therapy for spastic cerebral palsy in children
This study compares two types of hand and arm therapy to help children with spastic cerebral palsy use their affected side better. Children will either practice with the affected hand through special exercises or use mirror therapy, which uses a mirror to create the illusion of movement.
IslamabadAges 5–9 - NCT07747701Recruiting
Monitoring brain blood flow after stroke treatment to predict recovery
This study looks at whether monitoring brain blood flow after a blocked artery is opened can help predict if the treatment will be successful. It may help doctors identify who might need additional help after stroke treatment.
BeijingAges 18 years+ - NCT07748572Recruiting
Tracking safety and performance of brain aneurysm flow diverters
This study collects information from patients in France who are being treated for a brain aneurysm with specific flow diversion devices (p64, p48 MW, or p64 MW). The goal is to confirm that these devices are safe and work well in real-world use, which can help doctors make better treatment decisions.
AmiensAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,406 recruiting neurology studies from the U.S. registry right now, out of 19,323 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.