Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,941 recruiting studies in this area right now.
By phase
- Not applicable9,343
- Phase 2764
- Phase 1557
- Phase 3513
- Phase 4339
- Phase 1/Phase 2300
- Phase 2/Phase 3125
Top conditions
- Stroke796
- Parkinson Disease395
- Alzheimer Disease338
- Multiple Sclerosis329
- Dementia226
- Epilepsy193
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke139
- Sarcopenia135
- Mild Cognitive Impairment127
- Cerebral Palsy119
- Pain Management114
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California659
- Massachusetts305
- New York294
- Florida271
- Texas266
- Maryland248
- Alabama207
- Arizona207
- Illinois181
- Pennsylvania176
Recruiting studies11,941 total
- NCT06687018Recruiting
Comparing two hand therapies for carpal tunnel relief
This study tests two types of gentle hand and wrist movements (mobilizations) to see which better relieves pain, tingling, and numbness in carpal tunnel syndrome. It may help you if you have these symptoms and are otherwise healthy.
Lahore, Punjab ProvinceAges 20–45 - NCT06686186Recruiting
Hainan Community Memory Study
This study follows older adults in Hainan who live in the community. The goal is to understand thinking and memory changes over time.
Haikou, HainanAges 60–120 - NCT04449523Recruiting
Check for hidden heart rhythm problems after silent brain strokes
This study looks at how often “silent” atrial fibrillation—an irregular heart rhythm that can be symptom-free—happens in people who have silent brain stroke spots on MRI. If it finds a link, it may help identify which patients might benefit from closer heart monitoring or prevention steps.
GrazAges 50 years+ - NCT05685069Recruiting
Studying stroke risk factors in people with silent brain infarcts
This study looks for what may have caused “silent” mini-strokes in the brain that were found on MRI, and which risk factors might be changeable. It may help doctors better understand how to prevent future stroke in people who have no clear stroke symptoms from the finding.
ToursAges 16 years+ - NCT06419101Recruiting
Finding early signs of memory loss in China
This trial looks for new ways to diagnose memory and thinking problems earlier. It involves a memory test, brain scan, and blood draw to find markers that could help identify cognitive disorders.
BeijingAges 40–90 - NCT06683248Recruiting
Night shifts and menstrual cycle health study
This study looks at how working night shifts affects your health throughout your menstrual cycle. It aims to help understand the risks and support better health for shift workers.
Uppsala, Uppsala CountyAges 18–35 - NCT06681974RecruitingPhase 3
Throat therapy for sleep apnea without CPAP
This trial tests a type of mouth and throat therapy to see if it can help people with mild to moderate sleep apnea who can't or don't want to use a CPAP machine. It might be an option if you want a non-machine treatment for your sleep apnea.
SantanderAges 18–70 - NCT07638514Recruiting
Pain Relief After Heel Surgery: Catheter vs. Single Injection
This study compares two ways to manage pain after foot or heel surgery: using a small tube (catheter) that delivers medication over several days, or a single nerve-numbing injection. Researchers want to see which method works better for your recovery.
AngersAges 18 years+ - NCT07640542RecruitingEarly Phase 1
Brain imaging study for Parkinson's and MSA patients
This early-stage research trial tests a new brain-imaging tracer called [11C]MODAG-005 to help doctors better understand Parkinson's disease (PD) and multiple system atrophy (MSA). You would undergo PET/CT and MRI scans twice, a few weeks apart, to see how reliable the imaging is.
Tübingen, Baden-WurttembergAges 50–75 - NCT07642414Enrolling by invitation
Digital program combining exercises and mindfulness for migraines
This 12-week online program uses exercises, mindfulness, and digital tracking to help reduce migraines. You'll work with the app on your smartphone while staying on your current migraine medications.
San Francisco, CaliforniaAges 18 years+ - NCT07640555RecruitingEarly Phase 1
Brain imaging study for Parkinson's and related movement disorders
This research study tests a new type of brain scan (called a PET scan) that may help detect early signs of Parkinson's disease and similar conditions. You'll receive the scan and may have a spinal tap to check for specific protein markers.
New Haven, ConnecticutAges 50–80 - NCT07640191Recruiting
New Nerve Stimulation Device for Hard-to-Treat Epilepsy
This study tests a new implanted device that stimulates the vagus nerve (a major nerve in your neck) to help reduce seizures in people whose epilepsy doesn't respond well to medications. The device is surgically placed under the skin and may help lower how often you have seizures.
Herston, QueenslandAges 4–75 - NCT07645924RecruitingPhase 3
Elismetrep for fast relief of migraine attacks
This trial tests a new oral medication called elismetrep (K-304) for quickly stopping migraine pain and other symptoms. If you have regular migraines, this could offer a new option that works fast when a migraine starts.
Birmingham, AlabamaAges 18–75 - NCT07641179RecruitingPhase 2
Testing MAR002 for Acromegaly (a Pituitary Tumor Condition)
This study tests a new drug called MAR002 to treat acromegaly, a hormone disorder caused by a pituitary tumor that makes too much growth hormone. The drug is designed to help lower hormone levels and improve symptoms.
Phoenix, ArizonaAges 18–75 - NCT03495440Recruiting
Family skills program for youth with developmental disabilities
This trial studies a parent-and-family intervention designed for families of youth with developmental disabilities. It may help parents and siblings better understand needs and improve day-to-day support at home through guided, theory-based activities and surveys.
Fort Wayne, IndianaAges Any age - NCT05035693Recruiting
Follow-up study after a neck disc replacement surgery
This study tracks people after they get the MOVE-C artificial disc in the neck. It checks how well the device works over time and monitors safety and recovery.
ViennaAges 18 years+ - NCT06691230Recruiting
Looking at blood flow after stroke clot removal
This study uses a special CT scan to see how well blood flows in the brain after a stroke patient has had a procedure to remove a clot. The goal is to learn more about recovery and improve future care.
BaselAges 18 years+ - NCT05867940Recruiting
Exercise program for people with disabilities who are not active
This trial studies whether a structured physical activity program can improve health for people with disabilities who currently do not meet recommended activity levels. It focuses on reducing long periods of sitting and encouraging safer movement.
MalmöAges 8 years+ - NCT06032715Recruiting
Reducing sleep medication use in older adults
This trial tests a brief program to help older adults who use sleep medications (Z-drugs) too often or for too long, and see if they can safely reduce or stop them.
LørenskogAges 60 years+ - NCT06128226Recruiting
Screening study for CLN2 disease in 6-year-olds
This study is screening children for a rare genetic condition called CLN2 disease. It looks for signs like seizures, speech loss, and movement problems to find out how common this condition is among 6-year-olds.
AdanaAges 2–6 - NCT06557369Recruiting
New light therapy for intermediate age-related macular degeneration
This trial tests a new light-based treatment for intermediate age-related macular degeneration (AMD), a common eye condition that can lead to vision loss. The goal is to see if it is safe and helps slow down the disease.
BergamoAges 50 years+ - NCT06642532Recruiting
Using ultrasound to check brain blood flow after skull repair
This study uses a special ultrasound test to see how blood flow in the brain changes after you have surgery to replace a piece of your skull with a PEEK implant. It may help doctors understand if the surgery affects blood flow.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT04925414RecruitingPhase 4
Testing high-flow oxygen for migraine in the emergency room
This trial looks at whether breathing high-flow oxygen in the emergency department can help relieve migraine-like headaches. You may qualify if you are 18+ and are admitted to the ER for a migraine that fits standard diagnostic rules.
NiceAges 18 years+ - NCT06571032Recruiting
EEG guidance for brain stimulation after severe injury
This study tests whether using brain wave monitoring (EEG) can help guide electrical stimulation treatment for people with severe traumatic brain injury. It aims to see if this approach can improve recovery.
Shanghai, Shanghai MunicipalityAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,941 recruiting neurology studies from the U.S. registry right now, out of 18,432 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.