Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,764 recruiting studies in this area right now.
By phase
- Not applicable1,204
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 285
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- National Taiwan University Hospital16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona68
- Florida43
- Maryland39
- Texas37
- New York36
- Massachusetts35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,764 total
- NCT07619482Enrolling by invitationPhase 1/Phase 2
Insulin eye drops for glaucoma
This study tests whether insulin eye drops can help people with glaucoma by protecting the optic nerve. It is an early-stage trial that may offer a new way to manage the condition.
Palo Alto, CaliforniaAges 18–90 - NCT07613580Recruiting
Comparing two ways to record vision in eye studies
This study compares two ways of recording how well you can see (called BCVA) during a routine eye exam. It tests whether a new electronic method (Acuvera Capture) gives the same results as the traditional paper-based way, and it includes people with all levels of vision, from normal to very low.
CoimbraAges 18 years+ - NCT07618364Recruiting
Rinsing to reduce eye inflammation in dry eye disease
This study tests whether rinsing the eye surface helps reduce inflammation and symptoms in people with dry eyes. Participants must have a specific inflammatory marker (MMP-9) in both eyes.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07614776RecruitingPhase 3
New Eye Injection Treatment for Age-Related Macular Degeneration
This study tests whether a new eye injection called ABP 938 works as well as or better than the current standard treatment (Eylea) for wet age-related macular degeneration—a condition that causes vision loss in the center of your sight. You would receive injections into your eye every month for a year.
Fullerton, CaliforniaAges 50 years+ - NCT05672121RecruitingPhase 1/Phase 2
Gene therapy safety study for neovascular macular degeneration
This trial tests a new gene therapy drug (KH631) to see if it is safe and tolerated in people with neovascular age-related macular degeneration (nAMD). It may help your retina problems, but the early goal is mainly to learn about side effects and how the treatment behaves in the eye.
BeijingAges 50–85 - NCT04110067Recruiting
SMILE laser eye procedure for very high nearsightedness
This trial studies how well the SMILE laser procedure works to correct very high nearsightedness. It may help people with strong focusing power problems, as long as their eye measurements and cornea shape meet the study limits.
Münster, North Rhine-WestphaliaAges 18 years+ - NCT06000111Recruiting
Face down positioning after macular hole surgery
This trial compares different lengths of face down positioning after surgery for a macular hole. It aims to find the best duration to help the hole heal while being easier for patients.
Stoney Creek, OntarioAges 18 years+ - NCT06458595RecruitingPhase 1/Phase 2
Gene therapy for wet age-related macular degeneration (nAMD)
This trial tests a gene therapy (KH658) as a one-time treatment for wet macular degeneration. It's for people whose condition has been stabilized with anti-VEGF injections, and aims to see if it is safe and can reduce the need for frequent eye injections.
TianjinAges 50–85 - NCT06681688RecruitingPhase 1/Phase 2
Comparing two approaches to prevent cataract surgery complications
This study compares two ways to prevent complications after cataract surgery. One group gets a special combination of eye drops and a steroid injection before surgery, and the other group gets standard care. The goal is to see which approach leads to fewer problems after surgery.
Venice, FloridaAges 18 years+ - NCT06709690Recruiting
AI-powered PET/MR scanner for children with suspected cancer
This study tests a new, fast, and quiet AI-powered PET/MR scanner to take detailed pictures of children with suspected cancer. It aims to make the imaging experience easier and more comfortable for kids.
Shanghai, Shanghai MunicipalityAges Up to 18 years - NCT07606404Recruiting
Comparing surgical techniques for macular hole repair
This study compares ten different surgical methods for repairing full-thickness macular holes—small breaks in the central part of the retina that blur vision. You'd be in the study to help doctors learn which technique works best at restoring sight.
Almaty, AlmatyAges 18 years+ - NCT07606365RecruitingPhase 2
Testing a New Treatment for Geographic Atrophy
This study tests a new drug called STL303 for geographic atrophy, a condition where the back of the eye slowly loses cells, causing vision loss. The drug aims to slow or stop this vision loss in people over 60.
Bakersfield, CaliforniaAges 60 years+ - NCT07607496Recruiting
MacuTherm laser treatment study for intermediate age-related macular degeneration
This study tests a new laser treatment (MacuTherm) for intermediate age-related macular degeneration (iAMD), an eye condition that affects central vision. The study aims to see if this treatment can slow or prevent progression to more advanced stages of the disease.
DetmoldAges 60–90 - NCT05877560Recruiting
Noninvasive brain stimulation for eye focusing trouble
This study tests a noninvasive brain stimulation treatment to improve symptoms of convergence insufficiency, a condition that makes near vision tasks like reading harder. You may be randomly assigned to the study treatment or a comparison condition.
Downers Grove, IllinoisAges 18–40 - NCT07609628Recruiting
Silicon Oil's Effect on Retinal Nerve Function
This study examines how silicon oil (a clear liquid sometimes used to repair detached retinas) affects the electrical function of the retina. Researchers will use special eye tests to measure how well the retina responds to light after treatment.
Minya, Minya GovernorateAges 18–70 - NCT07606625RecruitingPhase 4
Nasal spray for dry eye disease and tear film stability
This study tests whether a nasal spray can improve dry eye symptoms and tear production in people with mild to moderate meibomian gland dysfunction (a common cause of dry eye). You'll use the spray daily while the research team monitors your eye health and comfort over several weeks.
Berkeley, CaliforniaAges 18 years+ - NCT07609186Recruiting
Sound therapy during cataract surgery in older adults
This study tests whether listening to special binaural sounds (through earphones) during cataract surgery helps older patients stay calm and comfortable. The surgery uses light sedation, and researchers want to see if the sounds improve the experience.
SeoulAges 65 years+ - NCT07606300Recruiting
Light Training to Help Light Sensitivity After Head Injury
This trial tests whether a training program using colored light targets can help reduce light sensitivity (photophobia) that some people experience after a traumatic brain injury. The training involves focusing your eyes on lights during several visits.
Columbus, OhioAges 18–80 - NCT07605572Recruiting
GLP-1 drugs and dry eye disease in type 2 diabetes
This study tests whether a diabetes and weight-loss medication called GLP-1 receptor agonists affects dry eye disease. Researchers want to see if this medication helps or worsens dry eyes in people with type 2 diabetes and obesity.
AthensAges 18 years+ - NCT07610226Recruiting
Cataract Surgery Lens for Prior Myopic Eye Surgery
This study tests a special intraocular lens (an artificial lens implanted during cataract surgery) designed for patients who had prior myopic refractive surgery (LASIK or PRK to correct nearsightedness). The goal is to achieve the best possible vision correction after cataract removal.
Greensboro, North CarolinaAges 18 years+ - NCT07604246Recruiting
How nicotine affects eye movements in e-cigarette users
This study looks at how nicotine from e-cigarettes affects eye movements and related behaviors. It involves two lab visits and may help understand nicotine's effects on the brain.
Columbus, OhioAges 21–50 - NCT07608367Recruiting
Hydrogel glue for eye surface repair surgery
This trial tests a new hydrogel glue that may replace stitches during eye surface repair surgery. It could help your eye heal faster and more comfortably after procedures like pterygium removal or corneal repair.
Jinan, ShandongAges 18–85 - NCT07605221Recruiting
Testing a formula for laser eye surgery astigmatism correction
This study develops a formula to help surgeons correct astigmatism (blurred vision from curved corneas) during a laser eye surgery called LASEK. If you're eligible, your surgery may be more precisely tailored to your eye shape.
Tianjin, Tianjin MunicipalityAges 18–45 - NCT06712758Recruiting
Cataract surgery with new technique for glaucoma patients
This trial tests a newer, gentler cataract surgery method in people who have both glaucoma and cataracts. It aims to lower eye pressure safely during the procedure.
GeelAges Any age
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,764 recruiting ophthalmology studies from the U.S. registry right now, out of 2,747 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.