Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,816 recruiting studies in this area right now.
By phase
- Not applicable1,253
- Phase 3130
- Phase 2121
- Phase 1120
- Phase 491
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract90
- Myopia89
- Diabetic Retinopathy52
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Macular Degeneration22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California141
- Arizona66
- Texas41
- Maryland39
- New York34
- Massachusetts33
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania21
Recruiting studies1,816 total
- NCT06351657Recruiting
Monitoring macular degeneration with AI to detect progression
This trial uses artificial intelligence to track changes in the eyes of people with advanced age-related macular degeneration (AMD) that has caused a specific type of damage (atrophy) in the retina. The goal is to see if AI can help detect when the disease gets worse, so doctors can personalize monitoring for each patient.
ViennaAges 55–99 - NCT06353542Recruiting
Glaucoma screening with AI for people with family history
This trial uses an artificial intelligence (AI) program to screen for glaucoma in people who have a family history of the disease. It aims to catch glaucoma early, when it can be treated more effectively.
Barcelona, BarcelonaAges 40–80 - NCT06355830Recruiting
A study of intermediate age-related macular degeneration
This study looks at people with intermediate age-related macular degeneration (AMD), a common eye condition that can affect central vision. The researchers want to better understand how AMD changes over time by using different types of eye scans. This may help find ways to monitor the condition and guide future treatments.
LisbonAges 55–95 - NCT06359548Recruiting
Repositioning the retina's inner layer for macular hole repair
This study tests a surgery for people with a small macular hole (a break in the retina's center). The surgeon repositions the inner layer of the retina to help the hole heal. It may be an option if you are between 50 and 80 and have not had eye surgery before.
ShanghaiAges 50–90 - NCT06359795Recruiting
PET Scan for Thyroid Eye Disease Activity
This study uses a special PET/CT scan (with a tracer called 18F-AlF-FAPI) to see how active your thyroid eye disease is. It may help doctors better understand and manage the condition.
Beijing, Beijing MunicipalityAges 18–80 - NCT06367530Recruiting
Trilateral retinoblastoma: incidence and outcomes
This study looks at how often trilateral retinoblastoma (a rare form that affects the brain as well as the eye) happens and what the outcomes are. It may help doctors better understand this condition.
Amsterdam, North HollandAges Any age - NCT06370104Recruiting
Online therapy for recent suicidal thoughts or behavior
This study tests a remote therapy program for people who have had suicidal thoughts or behaviors in the past month. It aims to provide timely support without needing to see a therapist in person.
Amsterdam, South HollandAges 16 years+ - NCT06371300Recruiting
Red vs Blue Light for Dry Eye With Mites
This study tests whether a special light (photobiomodulation) using red or blue light can help people with dry eye that is caused by both blocked oil glands and tiny eyelash mites. You'd receive 3 treatments, and we'd check how your eyes feel for a month after.
AucklandAges 18 years+ - NCT06375239Recruiting
Study of tests for tracking vision in retinal disease
This study will check if certain vision tests work well in people with retinal diseases like retinitis pigmentosa or Stargardt. Results will help design future trials.
Irvine, CaliforniaAges 18 years+ - NCT06379646Recruiting
YTS109 cell therapy for autoimmune disease
This study tests a new cell therapy (YTS109) for people with autoimmune diseases like lupus or Sjogren's syndrome that have not improved or keep coming back after standard treatments. It aims to see if the treatment can help control the disease.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT06380075Recruiting
Comparing two imaging systems for inherited retinal disease
This trial compares two different imaging systems (Clarus and Optos) to see how well they can capture images of the retina in people with inherited retinal diseases. The goal is to find which system works better for diagnosing and tracking these conditions.
Madison, WisconsinAges 18 years+ - NCT06380517RecruitingPhase 3
Headset therapy vs patching for lazy eye in children
This study tests a new way to treat lazy eye (amblyopia) in 4 to 7 year olds using special shows watched through a headset (dichoptic therapy). It compares this to the standard treatment of wearing a patch over the stronger eye. The goal is to see if the headset therapy works as well or better than patching.
Birmingham, AlabamaAges 4–7 - NCT06383273RecruitingPhase 3
Study of MELT-300 for sedation during cataract surgery
This trial tests a new sedative medication, MELT-300, to help you relax during cataract surgery. It's for people having surgery on one eye and aims to see if it works better than standard care.
Chico, CaliforniaAges 18–65 - NCT06389110RecruitingPhase 3
Low-dose atropine drops to slow children's nearsightedness
This study tests whether a very low-dose atropine eye drop (0.01%) can safely slow down worsening nearsightedness in children. It is for kids ages 3 to 12 who are already nearsighted but haven't used other myopia control treatments before.
Mexico CityAges 3–12 - NCT06389968Recruiting
Light therapy for vision after optic neuritis in MS
This study tests whether light stimulation can help improve vision after optic neuritis in people with multiple sclerosis. It may offer a way to support eye recovery without medication.
Munich, BavariaAges 18–60 - NCT06392711RecruitingPhase 1
Stem cell therapy for dry mouth not from radiation
This trial tests a new treatment using special cells (mesenchymal stromal cells) from your own bone marrow to help with dry mouth that is not caused by radiation. The goal is to see if it can increase saliva production and improve quality of life.
Madison, WisconsinAges 18–90 - NCT06392906RecruitingPhase 3
Radiation for Graves' Eye Disease: 1 vs 2 Weeks
This trial tests if a shorter course of radiation (1 week) works as well as a standard longer course (2 weeks) for treating active thyroid eye disease that did not improve enough with steroid medicine. It may be an option if you still have eye symptoms after steroid treatment.
Bangkok NoiAges 18–70 - NCT06393855Recruiting
Bandage contact lens shape and comfort after PRK surgery
This study tests whether different shapes of bandage contact lenses placed after PRK laser eye surgery affect pain and vision recovery. It may help people with moderate nearsightedness recover more comfortably.
Dongyang, ZhejiangAges 18–40 - NCT06394232RecruitingPhase 1/Phase 2
Testing a cell therapy for advanced dry AMD with geographic atrophy
This trial tests a new treatment called Eyecyte-RPE™, made from special cells that support the retina. It is given as a single injection under the retina during eye surgery. The study aims to see if it can help people with advanced dry age-related macular degeneration (AMD) who have large areas of damage (geographic atrophy) in the center of their vision.
Jālna, MaharashtraAges 50–100 - NCT06395285RecruitingPhase 1
Testing DF-003 for ROSAH syndrome with eye inflammation
This trial tests an oral medication called DF-003 for people with ROSAH syndrome who have eye inflammation (uveitis). The goal is to see if the drug is safe and tolerable. It might help reduce eye inflammation and other symptoms.
Bethesda, MarylandAges 18–65 - NCT06398158Recruiting
Ravulizumab and its impact on neuromyelitis optica
This study looks at how well ravulizumab (Ultomiris) works for people with neuromyelitis optica spectrum disorder (NMOSD) by tracking symptoms and MRI scans over time. It aims to see if the drug helps control the disease in real-world use.
Dallas, TexasAges 18 years+ - NCT06401811Recruiting
Turkish swallowing questionnaire study for Sjögren's syndrome
This study tests a Turkish version of a swallowing questionnaire (EAT-10) to see if it is reliable and accurate for people with primary Sjögren's syndrome. Taking part could help doctors better understand and track swallowing problems in this condition.
AnkaraAges 18 years+ - NCT06408701Recruiting
Lab-grown eye cells from people with eye problems
This study uses stem cells from people with eye malformations to grow tiny 3D eye organ-like structures in the lab. The goal is to better understand how eye problems develop, which could lead to new treatments in the future.
Clermont-FerrandAges 6 years+ - NCT06410833RecruitingPhase 4
Combination therapy for resistant Sjögren's in children
This trial tests a combination of two medicines, rituximab then belimumab, for children and teens with Sjögren's syndrome that hasn't improved with other treatments. The goal is to see if this two-step approach can better control symptoms like joint pain, skin rashes, and blood problems.
Beijing, Beijing MunicipalityAges 5–18
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,816 recruiting ophthalmology studies from the U.S. registry right now, out of 2,919 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.