Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,816 recruiting studies in this area right now.
By phase
- Not applicable1,253
- Phase 3130
- Phase 2121
- Phase 1120
- Phase 491
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract90
- Myopia89
- Diabetic Retinopathy52
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Macular Degeneration22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California141
- Arizona66
- Texas41
- Maryland39
- New York34
- Massachusetts33
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania21
Recruiting studies1,816 total
- NCT06413654RecruitingPhase 2/Phase 3
B001 for NMOSD: reducing relapses
This trial tests an investigational drug called B001 for people with NMOSD who have had recent relapses. The goal is to see if it can reduce future flare-ups.
BeijingAges 18 years+ - NCT06414590RecruitingPhase 2
Tebentafusp before surgery for eye melanoma
This trial tests a drug called Tebentafusp for a type of eye melanoma (uveal melanoma) that is too large to be removed without taking out the whole eye. The goal is to see if the drug can shrink the tumor before deciding on surgery.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06417502Recruiting
China pediatric rheumatic disease registry study
This study collects information from children with rheumatic and immune system diseases in China to better understand these conditions. By participating, you help researchers learn more about how to diagnose and treat these diseases.
Beijing, Beijing MunicipalityAges Up to 18 years - NCT06417216Recruiting
Virtual reality for single-eye nerve palsy
This study tests a virtual reality headset that uses head movements to help people with a single-eye nerve palsy move their eye better. It may help if you have limited eye movement due to a nerve condition.
Jacksonville, FloridaAges 18 years+ - NCT06424301RecruitingEarly Phase 1
Targeted gene therapy for hard-to-treat retinoblastoma
This trial tests an experimental drug that targets a specific gene (NUDT21) to treat retinoblastoma that has not responded to standard treatments. It is for children who have active tumor in only one eye and whose only other option is to remove the eye, but who want to try to save the eye instead.
ShanghaiAges 6 months+ - NCT06425666Recruiting
Cataract surgery with triple-DMEK for Fuchs dystrophy
This trial tests a combined surgery that treats both cataract and Fuchs endothelial corneal dystrophy at the same time. It compares the standard cataract surgery to one that also replaces the damaged cornea layer, aiming to improve vision with fewer steps.
Aarhus N, Central JutlandAges 18 years+ - NCT06426498Recruiting
Ultrasound and temporary blind spot study
This study tests whether a focused ultrasound technique can create a temporary blind spot in the vision. Researchers hope this will help them find the right ultrasound dose for each person, with the goal of treating certain brain conditions.
Charleston, South CarolinaAges 18–70 - NCT06428188RecruitingPhase 1/Phase 2
CAR-T cells targeting BCMA/CD19 for autoimmune diseases
This trial tests a new treatment called CAR-T cells that target two proteins (BCMA and CD19) on immune cells. It is for people with certain autoimmune diseases that have not improved with standard treatments.
Beijing, Beijing MunicipalityAges 21–90 - NCT06429280Recruiting
Lazy Eye Treatment Registry for Luminopia Users
This registry collects information from people with lazy eye who have used Luminopia treatment for at least 12 weeks. It helps researchers learn more about how the treatment works in real life.
San Ramon, CaliforniaAges Any age - NCT06433284Recruiting
Comparing two treatments for large macular holes
This study compares two ways to repair a large macular hole: one using a hydrogel made from donated amniotic membrane (the tissue that surrounds a baby during pregnancy), and one using a small flap of your own retina. The goal is to see which approach helps the hole close better and improves vision.
Nakhon Si Thammarat, ThasalaAges 18 years+ - NCT06435000Recruiting
A study tracking Stargardt disease progression
This study follows people with Stargardt disease (a genetic eye condition that causes vision loss) over time. It aims to learn more about how the disease progresses and does not test any treatment.
San Diego, CaliforniaAges 12–65 - NCT06445322Recruiting
Finding people with Stargardt disease for ACDN-01
This prescreening study looks for people with a specific genetic eye condition called Stargardt disease to see if they might be able to join a future trial for a new treatment called ACDN-01.
San Francisco, CaliforniaAges 5 years+ - NCT06445634Recruiting
A study of a new glaucoma surgery for closed-angle glaucoma
This trial tests a surgery called GATT combined with goniosynechiolysis to treat glaucoma patients whose eye drainage angle is closed due to scarring. It aims to lower eye pressure when medicines alone aren't working.
GizaAges Any age - NCT06446817Recruiting
High-add lens implant study for cataract patients
This study tests a new type of lens implant designed to help with both distance and near vision after cataract surgery. It is for people aged 50 and older with cataracts in both eyes who have not had any prior eye surgery.
MarseilleAges 50 years+ - NCT06451172RecruitingEarly Phase 1
New antibiotic eye drops for drug-resistant eye infections
This trial tests a new type of antibiotic eye drop for people with serious eye infections that don't respond to standard antibiotics. It aims to see if these drops can safely treat the infection and help improve vision.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06451575Recruiting
Blood Clots and Behçet's Disease Study
This study looks at how Behçet's disease affects blood clotting. If you have Behçet's disease and are between 18–70, you may help doctors understand why some people with Behçet's develop dangerous blood clots.
Erzurum, Üniversite MahallesiAges 18–70 - NCT06451718Recruiting
A new implant for keratoconus to avoid corneal transplant
This trial tests a small metal implant placed in the cornea to treat keratoconus, a condition where the cornea thins and bulges. The goal is to see if the implant can safely improve vision and prevent the need for a corneal transplant.
Roma, RomaAges 18 years+ - NCT06452316RecruitingPhase 1
Eye drop study for limbal stem cell deficiency
This study tests a new eye drop called CSB-001 for people with limbal stem cell deficiency (LSCD), a condition that damages the cornea. The goal is to see if the drops can help improve the health of the cornea and reduce inflammation.
Loma Linda, CaliforniaAges 18 years+ - NCT06453694RecruitingPhase 2
Efgartigimod for first-time optic neuritis
This trial tests a drug called efgartigimod for people having their first episode of optic neuritis (inflammation of the optic nerve). The goal is to see if it can help protect your vision better than standard treatment alone.
Boston, MassachusettsAges 18 years+ - NCT06454370Recruiting
New imaging vs standard biopsy for Sjögren's diagnosis
This trial compares a new, quick imaging method (called full-field optical coherence tomography) with the standard lab analysis of a saliva gland biopsy. It may help diagnose Sjögren's syndrome faster and with less discomfort.
Mâcon, Sâone-et-LoireAges 18–99 - NCT06458088Recruiting
Sugar-related substances and blood vessel problems in type 1 diabetes
This study looks at how certain sugar-related substances in the blood (called advanced glycation products) are linked to blood vessel problems in people with type 1 diabetes. It follows up with participants from an earlier study at Reims Hospital.
ReimsAges 18 years+ - NCT06458595RecruitingPhase 1/Phase 2
Gene therapy for wet age-related macular degeneration (nAMD)
This trial tests a gene therapy (KH658) as a one-time treatment for wet macular degeneration. It's for people whose condition has been stabilized with anti-VEGF injections, and aims to see if it is safe and can reduce the need for frequent eye injections.
TianjinAges 50–85 - NCT06467344RecruitingPhase 1/Phase 2
Testing ACDN-01 for ABCA4 Stargardt eye disease
This trial tests an experimental medicine called ACDN-01 for people with Stargardt retinopathy caused by ABCA4 gene mutations. The goal is to see if it can slow or stop vision loss in an eye with already damaged central vision.
San Francisco, CaliforniaAges 12 years+ - NCT06474520Recruiting
Bovine gallstone extract for inflammatory brain disease
This trial tests a natural substance called Calculus Bovis Sativus (CBS) to see if it helps people with certain inflammatory brain conditions like multiple sclerosis, neuromyelitis optica, MOGAD, or ADEM. The goal is to find out if it is safe and effective.
Wuhan, HubeiAges 18 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,816 recruiting ophthalmology studies from the U.S. registry right now, out of 2,919 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.