Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,760 recruiting studies in this area right now.
By phase
- Not applicable1,199
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 286
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- National Taiwan University Hospital15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona69
- Florida43
- Maryland39
- Texas37
- Massachusetts35
- New York35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,760 total
- NCT06842316Recruiting
Study on cannabis-like compounds for inflammatory arthritis
This trial tests whether plant-based compounds similar to cannabis (called phytocannabinoids) can help calm inflammation and improve immune function in people with certain types of arthritis or autoimmune diseases like lupus or Sjögren's disease. It aims to offer a new way to treat these conditions without the 'high' of marijuana.
OrléansAges 18 years+ - NCT06844240Enrolling by invitation
Testing the safety and effectiveness of the XEN63 gel implant for glaucoma
This study tests a new gel implant (XEN63) to lower eye pressure in adults with open-angle glaucoma. It may be an option if your eye pressure remains high despite using eye drops, or if you can't tolerate the drops.
Acquaviva delle Fonti, ItalyAges 18 years+ - NCT01756365Recruiting
Stem cell eye treatment from your own cornea cells
This trial tests an eye treatment made from your own cornea surface cells, grown in a lab and put back into the eye. It may help people with limbal stem cell deficiency by improving the health of the eye surface after a cell biopsy.
Toronto, OntarioAges 1 year+ - NCT05200715Recruiting
Registry study for inherited and inflammatory eye and joint diseases
This study is a registry, meaning it collects your medical information to better understand several inflammatory (auto-inflammatory) conditions. It may help doctors and researchers improve diagnosis and future treatments for people with these disorders.
AlgiersAges Any age - NCT06662994RecruitingPhase 4
High dose aflibercept for diabetic macular edema after vitrectomy
This trial tests a high-dose version of the drug aflibercept (given as an eye injection) for people with diabetic macular edema who have previously had a vitrectomy surgery. The goal is to see if this higher dose can help reduce swelling and improve vision.
Fullerton, CaliforniaAges 21 years+ - NCT06825702RecruitingPhase 2
Testing KIO-104 eye injection for macular edema
This trial tests an eye injection called KIO-104 to treat macular edema (swelling in the center of the retina) caused by conditions like uveitis, diabetes, or vein blockage. The goal is to see if it is safe and improves vision.
Sydney, New South WalesAges 18–85 - NCT06834906Recruiting
Usability test of the Easy-EyeFM AI platform
This study tests how easy it is to use the Easy-EyeFM AI platform, a new tool that may help with eye exams. If you are a medical student or doctor, you can help by using the platform for about an hour and sharing your experience.
BeijingAges 18–80 - NCT06827535Enrolling by invitation
Long-term study of eye changes in glaucoma and high eye pressure
This study tracks changes in blood flow, structure, and vision over time in people with glaucoma or high eye pressure. It aims to understand how these conditions progress, which could help improve future treatment.
Milan, ItalyAges 18 years+ - NCT06829524Recruiting
Study of satralizumab for NMOSD (real world evidence)
This study looks at how well satralizumab works in people with NMOSD (a rare disorder that affects the nerves in your eyes and spine). It is for people who have had recent flare-ups and test positive for a specific antibody (AQP4). You will receive satralizumab and be followed for at least one year to see if your disease stays under control.
Shanghai, Shanghai MunicipalityAges 12 years+ - NCT06828042RecruitingPhase 1/Phase 2
CAR-γδT cells for refractory autoimmune diseases
This trial tests a new type of immune cell therapy (CAR-γδT cells) that targets a protein called CD19 on your own B cells. It is for people with certain autoimmune diseases that have not gotten better with standard treatments. The goal is to see if this therapy can safely control the disease.
BeijingAges 18–80 - NCT06817265RecruitingPhase 3
TNTL for diabetic eye disease (non-proliferative)
This study tests if a drug called TNTL can help people with type 2 diabetes who have early-stage diabetic eye disease (non-proliferative diabetic retinopathy) without severe vision loss. It aims to see if the treatment is safe and effective in slowing or improving the condition.
Xuancheng, AnhuiAges 18–75 - NCT06822738RecruitingPhase 3
Study of XEN63 gel stent for glaucoma patients
This trial tests a new gel stent (XEN63) to lower eye pressure in adults with glaucoma. It compares two ways of putting the stent in the eye, and may help people who have not had success with other treatments.
Glendale, ArizonaAges 45 years+ - NCT06816446Recruiting
Do special glasses slow myopia in children?
This trial tests whether special Rodenstock glasses can slow down the worsening of nearsightedness (myopia) in children. It's for kids aged 6 to 12 who have never had myopia treatment before.
SingaporeAges 6–12 - NCT06818747Recruiting
Comparing two cornea transplant methods for advanced bullous keratopathy
This trial compares two types of cornea transplant surgery (PKP and DSAEK) to see which one helps people with severe corneal swelling see better after two years. It may be an option if you have advanced bullous keratopathy and need a first-time cornea transplant.
BesançonAges 50 years+ - NCT06824935Enrolling by invitation
Cataract surgery anesthesia needs study
This study looks at how much anesthesia is needed during outpatient cataract surgery. It may help find the right approach for your comfort and safety.
IstanbulAges 18 years+ - NCT06821399Recruiting
Better eye care for type 2 diabetes
This study is testing a better way to diagnose and manage eye problems (diabetic retinopathy) in people with type 2 diabetes. It aims to improve how doctors find and treat these issues to help protect your vision.
LanzhouAges 20–79 - NCT06805825RecruitingPhase 1
Study of NN3201 for advanced cancers with c-Kit
This trial tests a new drug, NN3201, that targets a protein called c-Kit found on some cancer cells. It may be an option for people with certain advanced solid tumors, including GIST, small cell lung cancer, or other c-Kit-positive cancers, who have already tried standard treatments or cannot take them.
Ann Arbor, MichiganAges 18 years+ - NCT06806085Recruiting
Understanding vision quality factors after smile eye surgery
This study looks at how SMILE eye surgery (a type of laser vision correction) affects tiny imperfections in the way light enters the eye, especially when a thin layer of corneal tissue is left in place. It may help people with nearsightedness understand how this surgery option affects their vision quality.
Nanchang, JiangxiAges 18–45 - NCT06775808Recruiting
Understanding eye infections through DNA testing
This study looks at eye infections by testing leftover fluid or tissue samples to find all possible germs, including viruses, bacteria, and fungi. It may help doctors better understand what causes different eye infections and improve treatment.
Shanghai, Shanghai MunicipalityAges Any age - NCT06798766Recruiting
Understanding darker skin tones and vein disease care
This study looks at how people with darker skin tones experience chronic venous insufficiency (a condition that affects blood flow in the legs) and aims to improve how it's diagnosed and treated. It involves two parts: one is sharing your experience through an interview, and the other includes a skin check and photos at the hospital.
London, LondonAges 18 years+ - NCT06796673Enrolling by invitation
Retina biobank study for vitreoretinal disease
This study collects retina fluid samples from people getting treatment for a vitreoretinal disease. It aims to find better ways to understand and manage these conditions.
Bellaire, TexasAges 18 years+ - NCT05694858RecruitingPhase 1/Phase 2
Numbing patch comparison before blood draw for eye care
This trial tests a numbing skin patch made with tiny microneedles against a standard numbing cream/patch to reduce pain before a blood draw. It may help you feel less discomfort during venepuncture before an eye procedure.
Kuala Lumpur, Kuala LumpurAges 18 years+ - NCT06789445RecruitingPhase 1/Phase 2
Cell therapy for inherited retinal disease (CLARICO)
This study tests a new cell therapy (OpCT-001) for adults with inherited retinal diseases that affect the light-sensing cells. It aims to see if the treatment is safe and possibly helps improve vision.
Los Angeles, CaliforniaAges 18 years+ - NCT06729710Recruiting
Prism Adaptation for Symptomatic Inward Eye Turn – Shorter Timing
This trial tests whether adjusting prism glasses over a shorter time helps people with symptomatic inward eye turn (esophoria) and whether surgery results are better after that adaptation. It may be helpful if you have double vision, eye strain, or headaches that worsen with fatigue or reading.
CopenhagenAges 18–65
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,760 recruiting ophthalmology studies from the U.S. registry right now, out of 2,756 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.