Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,816 recruiting studies in this area right now.
By phase
- Not applicable1,252
- Phase 3131
- Phase 2121
- Phase 1120
- Phase 491
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract90
- Myopia89
- Diabetic Retinopathy53
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Macular Degeneration22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California143
- Arizona66
- Texas41
- Maryland39
- New York34
- Massachusetts33
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania21
Recruiting studies1,816 total
- NCT07453992Recruiting
Comparing three toric lenses for cataract and astigmatism
This study compares three types of toric lenses (lenses that correct both cataracts and astigmatism) to see how well they stay in place after surgery. It may help you choose the best lens for your cataract surgery.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07454447Recruiting
Eye exam after new glaucoma surgery
This trial uses a special ultrasound to look at the eye after a certain type of glaucoma surgery. It helps doctors see how well the surgery is working for people with open-angle glaucoma.
Minya, Minya GovernorateAges Any age - NCT07455786Recruiting
Modified glaucoma surgery after failed combined cataract and GATT
This trial tests a modified trabeculectomy (a type of glaucoma surgery) for people whose earlier combined cataract and minimally invasive glaucoma surgery (GATT) did not work well.
AsyutAges 21–70 - NCT07458516Recruiting
Observing eye disease progression in type 2 diabetes
This study closely follows people with type 2 diabetes who have early signs of diabetic retinopathy (damage to the retina from diabetes) to see how the condition changes over time. It does not test a new treatment but monitors the eye's health closely. It may be a good fit if you have diabetic retinopathy that does not need immediate treatment.
CoimbraAges 35–80 - NCT07460557Recruiting
Link between jaw shape and vision
This study looks at how the shape of your jaw and face might relate to your eyesight. Healthy young adults aged 21 to 25 are needed to see if there is a connection.
ZagrebAges 21–25 - NCT07460791Recruiting
Long-term look at Hydrus stent after 8 years
This study is checking how the Hydrus implant (a tiny device for glaucoma) is doing more than 8 years after it was placed. It aims to see if the eye pressure is still controlled and if the eye is healthy. If you were in one of the earlier Hydrus studies in Mainz and had the implant with or without cataract surgery, this follow-up may be for you.
Mainz, Rhineland-PalatinateAges Any age - NCT07461441RecruitingPhase 3
Personalized faricimab for new polypoidal choroidal vasculopathy
This study tests a personalized treatment plan using an investigational drug called faricimab for people who have a specific type of wet age-related macular degeneration known as polypoidal choroidal vasculopathy. The goal is to see if adjusting the time between injections based on your individual needs can safely dry up fluid in the retina and improve vision.
Daegu, NamguAges 50 years+ - NCT07462000Recruiting
Eye fluid and tissue analysis in glaucoma and cataract
This study collects eye fluid and tissue samples during planned cataract or combined cataract-glaucoma surgery to analyze differences between people with and without glaucoma. It may help researchers understand eye disease better.
WarsawAges 18 years+ - NCT07465913RecruitingPhase 4
Rocklatan vs Latanoprost after DSLT laser
This study compares two eye drops—Rocklatan and latanoprost—for people with open-angle glaucoma who have already had a laser treatment (DSLT). It tests whether one drop works better than the other at lowering eye pressure after the laser.
Beaumont, TexasAges 18 years+ - NCT07468058Recruiting
Diabetic eye disease study in Da Nang
This study looks at how common diabetic retinopathy is and what factors increase the risk. It may help find better ways to prevent vision loss in people with diabetes.
Da NangAges 18 years+ - NCT07468877Recruiting
Comparing two cataract surgery systems for bilateral cataract removal
This trial compares two machines used during cataract surgery to see which one uses less energy and ultrasound time. If you are healthy and need cataract surgery in both eyes, this study might help determine the best approach.
Los Angeles, CaliforniaAges 18 years+ - NCT07476053Recruiting
How light exposure affects migraine and sleep
This study looks at how office lighting and sleep quality affect migraine. You'll track your headaches and light exposure. The goal is to find ways to improve sleep and reduce migraine attacks.
Tempe, ArizonaAges 18 years+ - NCT07480720Recruiting
Thyroid autoimmunity and eye changes in Graves disease
This study looks at how inflammation and thyroid autoimmunity in Graves disease may cause changes in the retina at the back of the eye. It uses a special eye scan (OCT) to measure those changes and compares results between people with Graves disease and healthy volunteers.
Elâzığ, ElaziğAges 18 years+ - NCT07481487Recruiting
Cataract and vision correction surgery outcomes
This trial looks at results after cataract or vision correction surgery, like lasik or lens implants. It helps doctors improve care.
Bristol, EnglandAges 18 years+ - NCT07482228Recruiting
Long-term outcomes after retinal artery occlusion
This study looks at the long-term health results of people who have a retinal artery occlusion (a blockage in the blood vessels of the eye). It aims to understand what happens over time, which can help guide treatment and care.
Gwangju, GwangjuAges Any age - NCT07672899Recruiting
Study on tRF-31 changes in age-related cataract patients
This study looks at a small RNA molecule called tRF-31 in people with age-related cataracts. Researchers want to see how it changes, which may help understand cataracts better.
Hangzhou, ZhejiangAges 18 years+ - NCT06970106RecruitingPhase 1/Phase 2
Study of PYC-001 eye injections for people with a type of inherited optic nerve disease
This trial tests a new medicine called PYC-001, given as an injection into the eye, for people with a specific genetic form of vision loss called autosomal dominant optic atrophy (ADOA). It aims to see if the treatment is safe and could help protect or improve vision.
Sydney, New South WalesAges 18 years+ - NCT07674290RecruitingPhase 4
Study of MC4R Agonist for Bardet-Biedl Syndrome and Genetic Obesity
This trial tests a drug called setmelanotide for people with Bardet-Biedl Syndrome (a rare genetic condition) or other severe genetic obesity. It looks at how well the drug works in real-world settings, not just in a lab.
EssenAges Any age - NCT07674069Recruiting
Pilot study of a portable vision field machine
This pilot study tests a new portable device for measuring your field of vision during a glaucoma clinic visit. You may benefit from a quicker or more convenient test.
AylesburyAges 18–99 - NCT07495852RecruitingPhase 3
Implant for eye pressure in glaucoma or ocular hypertension
This trial tests a tiny implant that slowly releases medication inside the eye to lower pressure. It is for people with open-angle glaucoma or high eye pressure who have not had certain eye surgeries.
Dothan, AlabamaAges 18 years+ - NCT07496957Recruiting
A new glaucoma surgery: Preserflo versus trabeculectomy
This trial compares two types of glaucoma surgery to see which one works better for people with specific kinds of open-angle glaucoma whose eye pressure isn't controlled by eye drops or laser.
Bialystok, PolskaAges 21 years+ - NCT07500324Recruiting
Searching for new markers in age-related eye diseases
This study looks for proteins in the blood and eye fluids that may help doctors better understand and monitor three common eye conditions: age-related macular degeneration, diabetic retinopathy, and retinal detachment. If you have one of these conditions, or if you are a healthy control with no retinal disease, you may be able to help by giving a small sample of blood or fluid from your eye during a routine procedure.
Roma, ItalyAges 18 years+ - NCT07502456Recruiting
Clareon TruPlus study for cataract patients with astigmatism
This trial tests a new type of lens (toric IOL) to correct both cataracts and astigmatism in one surgery. It may help you see clearly without glasses if you have cataracts and a mild to moderate astigmatism.
Phoenix, ArizonaAges 22 years+ - NCT07502664Recruiting
A study on vision and navigation in inherited retinal disease
This study is looking at how people with inherited retinal disease that affects peripheral vision see and move around. It will test a new way to measure vision and navigation to see if it can help doctors understand how the disease affects daily life.
Irvine, CaliforniaAges 18 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,816 recruiting ophthalmology studies from the U.S. registry right now, out of 2,924 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.