Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,613 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3438
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke796
- Heart Failure535
- Hypertension389
- Cardiovascular Diseases374
- Coronary Artery Disease362
- Multiple Myeloma328
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona182
- Massachusetts174
- New York166
- Florida141
- Texas122
- Maryland118
- Minnesota118
- Illinois111
Recruiting studies9,613 total
- NCT07492498Recruiting
Village doctor telehealth to prevent heart failure in af
This study tests whether regular support from village doctors using telehealth (remote check-ins) can help prevent heart failure in people with atrial fibrillation, a common heart rhythm problem. The goal is to catch early signs and keep your heart healthier.
Yancheng, DongtaiAges 65–80 - NCT07492524Recruiting
Village doctor telehealth program for heart failure with atrial fibrillation
This trial tests a program where village doctors use telehealth to support patients who have both atrial fibrillation (an irregular heartbeat) and heart failure (when the heart doesn't pump well). It aims to improve their health and quality of life.
Yancheng, DongtaiAges 65–80 - NCT07494643Recruiting
Fluid response in children on low-tidal-volume ventilation
This study checks if giving fluids helps children on a ventilator with circulation problems. Doctors will use ultrasound to see how the heart responds to a small fluid boost.
AmiensAges birth–15 years - NCT06768398Recruiting
AI study for heart and blood vessel health
This study uses artificial intelligence (AI) to analyze medical images of blood vessels. It aims to help patients with heart or blood vessel conditions, including smokers and those with high blood pressure, by improving how doctors spot problems early.
ShatinAges 19 years+ - NCT07490613RecruitingPhase 1
Study of SHR-3836 for people with multiple myeloma
This trial tests a new drug called SHR-3836 for patients with multiple myeloma that has come back or stopped responding to treatment. The goal is to see if the drug is safe and how it works against the cancer.
Suzhou, JiangsuAges 18 years+ - NCT07496372RecruitingPhase 3
Stem cell injection for advanced heart failure
This trial tests a treatment made from stem cells that are turned into heart muscle cells and injected directly into the heart. It is for people with advanced heart failure who are already on the best available medicines and who are scheduled to have bypass surgery.
Tianjin, Tianjin MunicipalityAges 18–75 - NCT07493304RecruitingPhase 3
Preventing blood clots in people with cancer
This trial tests a new anticoagulant medication to treat and prevent blood clots in patients with active cancer. You may qualify if you have a recent clot in your leg or lungs and are already taking a blood thinner.
Hialeah, FloridaAges 18 years+ - NCT07491107Recruiting
Registry of a new drug-eluting stent for complex coronary lesions
This study tracks how well a new drug-eluting stent (a small mesh tube that keeps arteries open and releases medicine to prevent re-narrowing) performs in people with complex coronary artery disease. It aims to see if the stent is safe and effective in real-world patients with long, calcified, or multiple blocked arteries.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT07493135RecruitingEarly Phase 1
IMV102 for relapsed/refractory multiple myeloma
This early-phase trial tests an experimental drug called IMV102 for people with multiple myeloma that has come back or stopped responding to at least 3 prior treatments. The study aims to see if IMV102 is safe and how well it works.
BeijingAges 18–80 - NCT07498218RecruitingPhase 1
Studying VELGRAFT for diabetic foot ulcers
This trial tests a new treatment called VELGRAFT, which is made from living cells, for diabetic foot ulcers that haven't healed with standard care. The goal is to see if it can help the wound close and heal more effectively.
Phoenix, ArizonaAges 18 years+ - NCT06767501Recruiting
Amnion graft for diabetic foot ulcers vs. standard care
This trial tests whether a special amnion membrane graft can help heal diabetic foot ulcers better than standard care alone. If you have a diabetic foot ulcer that hasn't healed after standard treatment, this study may offer a new option.
Roanoke, VirginiaAges 18 years+ - NCT05702476Recruiting
Non-invasive 3D scan study for Marfan face features
This study uses a non-invasive 3D scan to better measure facial features in people with Marfan syndrome. It may help researchers describe face differences more accurately, without needles or surgery.
San Donato Milanese, LombardyAges Any age - NCT06646484Recruiting
Using a device to check hydration after brain bleeding
This study tests a new way to monitor your body's water and sodium levels using a simple, painless device (impedancemetry) after a subarachnoid hemorrhage. It may help doctors better manage your hydration and prevent complications during your ICU stay.
Lyon, FranceAges 18 years+ - NCT06632613RecruitingPhase 2
Trial of ENN0403 to prevent kidney injury after heart surgery
This study tests a new drug (ENN0403) given during heart surgery to see if it prevents acute kidney injury—a sudden drop in kidney function. The trial is for people who are already at higher risk due to their specific heart surgery and other health factors.
ShanghaiAges 18–85 - NCT06688448Recruiting
New biologic aortic valve replacement study
This study is testing a new generation of biologic (tissue) replacement valves for the aortic valve in adults aged 18 to 65. It aims to see how well these newer devices work compared to standard options.
São Paulo, São PauloAges 18–65 - NCT04184635Recruiting
ECMO for heart-attack shock in the ICU
This trial studies whether using a life-support machine called ECMO (extra support for the heart and lungs) helps people who develop shock right after a heart attack. It aims to improve outcomes when blood flow is failing and organs may be struggling.
ParisAges 18 years+ - NCT06772038Recruiting
Fluid response and vein health during fluid bolus in ICU
This trial looks at how well your body responds to extra fluids given through an IV, and whether it helps your veins. It is for people in the ICU who already have heart monitoring in place.
Guangzhou, GuangdongAges 18–99 - NCT05667805RecruitingPhase 4
Testing blood clotting in people with liver cirrhosis
This Phase 4 study looks at how clotting measurements relate to bleeding risk in people with liver cirrhosis who need a planned liver procedure. The study may help doctors understand what coagulation results mean when doing these procedures safely.
ViennaAges 18 years+ - NCT05796739Recruiting
Stress testing once or only when needed for high calcium risk
This study compares two approaches to stress testing in people who feel fine but have high coronary artery calcium on a scan. It may help determine whether testing routinely is better than doing it only if symptoms or concerns arise.
SeoulAges 19 years+ - NCT06775028Recruiting
Integrated care for older adults with atrial fibrillation
This trial is testing a new approach to care for older adults with atrial fibrillation (an irregular heartbeat) who also have other health conditions. It aims to see if a more integrated, team-based care plan helps improve their overall health and quality of life.
HaskovoAges 65 years+ - NCT06774586Recruiting
Study of blood vessel health in children
This study examines the health of blood vessels in children ages 6 to 17, using a non-invasive device called Vicorder to measure vessel stiffness. It aims to understand how blood vessel walls work in youth.
BolognaAges 6–17 - NCT06772922Recruiting
Pulmonary and heart rehab program testing combined exercise
This trial studies a combined lung and heart rehabilitation program for people with lung diseases (like COPD, asthma, or fibrosis) or heart conditions (like heart attack, bypass surgery, or heart failure). The goal is to see if a special exercise program can improve your health and quality of life.
Campinas, São PauloAges 18 years+ - NCT06774794Recruiting
Precision medicine for heart transplant patients
This trial uses precise, personalized approaches to manage heart transplant recipients. It involves taking a small heart muscle sample (a biopsy) to monitor for rejection or routine checks.
BolognaAges 18 years+ - NCT06773611Recruiting
Heart failure and transplant registry study
This study is creating a registry to track and learn from people with advanced heart failure or who have had a heart transplant. By joining, you help researchers better understand these conditions and improve care.
BolognaAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,613 recruiting cardiology studies from the U.S. registry right now, out of 14,690 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.