Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,982 recruiting studies in this area right now.
By phase
- Not applicable7,962
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke844
- Heart Failure566
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California465
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois118
- Texas118
Recruiting studies9,979 total
- NCT04184635Recruiting
ECMO for heart-attack shock in the ICU
This trial studies whether using a life-support machine called ECMO (extra support for the heart and lungs) helps people who develop shock right after a heart attack. It aims to improve outcomes when blood flow is failing and organs may be struggling.
ParisAges 18 years+ - NCT04185285Recruiting
Heart procedure registry for people who had stents
This trial is a registry that collects information from people who receive a heart artery procedure (percutaneous coronary intervention) at the study hospital. It mainly helps researchers understand outcomes and care patterns, and it only requires your consent to participate.
FribourgAges 17–120 - NCT04185844Recruiting
Chronic kidney health study for Native American adults
This study follows Native American adults with kidney function changes (either moderately reduced kidney filtration or early urine protein). It aims to better understand kidney disease over time and what factors predict progress, which may help improve care for people like you.
Phoenix, ArizonaAges 21–80 - NCT04189471Recruiting
Improving care for people in the Neuro ICU
This trial looks at improving outcomes for people who have a potentially life-threatening neurologic illness and are admitted to a Neuro ICU soon after injury. If you qualify, you may receive care strategies being tested to improve recovery and survival.
Baltimore, MarylandAges 18 years+ - NCT04187443RecruitingPhase 1
Drug MS-553 for diabetic eye swelling with reduced vision
This Phase 1 trial tests MS-553 to see how it works and how safely it can be given to people with diabetic retinopathy causing central macular swelling (macular edema). You may be considered if your vision and eye scan results match, and if you can follow frequent study visits.
Changsha, HunanAges 18 years+ - NCT04188522Recruiting
MEG study of memory after a small stroke
This study uses a special brain scan called MEG to understand how thinking and memory change after a small ischemic stroke. If you qualify, you may get scanned about 4–6 weeks after your stroke and help researchers learn what brain signals relate to recovery.
Baltimore, MarylandAges 18–100 - NCT04188808Recruiting
Study comparing patients with artery disease before surgery
This study looks at people with blocked leg arteries who are having planned (elective) open surgery for symptoms like leg pain when walking or at rest. It aims to better understand what to expect in these patients and how to compare outcomes between groups.
GothenburgAges Any age - NCT04190849Recruiting
Children’s liver fat disease registry in Europe
This is a registry study collecting information about children and teens with fatty liver disease that isn’t caused by alcohol. It aims to better understand this condition and may help future research and treatments.
MaastrichtAges Up to 18 years - NCT04190602Recruiting
Registry study for NeoChord artificial mitral valve chord
This study keeps track of people who had NeoChord treatment to help understand how well it works in everyday care. You may be included if you had a certain type of mitral valve leakage (regurgitation) and the procedure happened after 2016.
BonnAges 18 years+ - NCT04191681RecruitingPhase 4
Testing ARNI in people with implanted LVAD devices
This trial studies whether a heart medicine called ARNI (sacubitril-valsartan) is safe and works well for people who have a durable LVAD and moderate-to-severe heart pumping weakness. It may help improve symptoms and outcomes, while carefully checking side effects in this higher-risk group.
Cleveland, OhioAges 18 years+ - NCT04194372Recruiting
Health study of risk markers in people with metabolic conditions
This study looks at your health “risk profile” in a hospital group of people with metabolic conditions like diabetes, obesity, or metabolic syndrome. It mainly focuses on measuring factors to better understand who is at higher risk of health problems over time.
Boulogne-sur-MerAges 18 years+ - NCT04193475Recruiting
Uses computer learning to improve stress heart ultrasound
This study uses computer technology (“machine learning”) with stress echocardiogram images (a heart ultrasound done during stress) to improve how heart function is measured. If you are able to have a stress echocardiogram, you may be able to help test a better way to interpret the results.
CottinghamAges 20–89 - NCT04194619Recruiting
Study of pregnancy safety in women with rare blood-vessel diseases
This study looks at pregnancy and the early period after birth in women with rare diseases that affect blood vessels. It may help doctors understand risks and improve care for future pregnancies.
AngersAges 18–45 - NCT04196712Recruiting
Heart artery testing registry during coronary angiography
This trial is a registry that collects information from people undergoing an invasive heart artery test (coronary angiography). It helps researchers understand heart disease and outcomes in real-world patients.
Essen, North Rhine-WestphaliaAges Any age - NCT04195984Recruiting
Heart valve replacement through a catheter for leaky mitral valve
This trial studies a new way to replace a damaged mitral heart valve using a catheter (a thin tube), instead of open-heart surgery. It may help people who have severe leaking of the mitral valve but are considered too high-risk for surgery.
Beijing, Beijing MunicipalityAges 65 years+ - NCT04196842Recruiting
Heart failure precision medicine study using heart tests and blood tests
This study looks at how “personalized” (precision) treatment planning for heart failure may work, using results from heart imaging (echocardiogram) or a blood test called B-type natriuretic peptide. You may join if you have heart failure and can follow frequent study check-ins.
Sacramento, CaliforniaAges 21 years+ - NCT04197258Recruiting
Peer support after stroke for people going home from rehab
This study tests whether a personal “peer” supporter can help you after discharge home following a stroke. It’s meant to improve how stroke patients cope and to understand what support works best.
Saint-Genis-LavalAges 18 years+ - NCT04197648Recruiting
Supervised exercise study for certain thoracic aneurysms
This study looks at whether a supervised exercise program is safe and helpful for people with a thoracic (chest) aortic aneurysm. You may be able to join if your aneurysm size fits their range and you can safely attend training visits.
Québec, QuebecAges 18 years+ - NCT04198792Recruiting
Finding outcomes after ECMO for heart-related emergencies
This study looks at what helps determine survival and better brain function after people are treated with ECMO, a heart-lung support machine. It may help doctors understand who is most likely to do well after this kind of emergency treatment.
GothenburgAges 16 years+ - NCT04201015RecruitingPhase 2/Phase 3
Testing exercise pacing to improve heart pumping
This trial tests whether “pacing” your exercise (doing it at the right rate) can improve how strongly your heart pumps. It’s for people with heart failure who have a pacemaker and can safely do an exercise test.
LeedsAges 18 years+ - NCT04201964Recruiting
TNK treatment for stroke when blood flow didn’t reopen enough
This trial looks at giving a clot-busting medicine directly into the brain arteries (intra-arterial TNK) when a stroke procedure (thrombectomy) doesn’t reopen the blocked vessel enough. It aims to improve recovery by improving blood flow while checking for safety, especially bleeding risk.
ShenyangAges 18 years+ - NCT04204642Recruiting
Testing MRI findings to find markers of brain blood vessel disease
This study looks at brain MRI scans in people with cerebral amyloid angiopathy (a condition where amyloid builds up in brain blood vessels). The goal is to search for “biomarkers,” or measurable scan features, to better understand and detect the disease in some people before symptoms or during symptoms.
Milan, MilanoAges 55 years+ - NCT04204915Recruiting
Early valve replacement for severe but symptom-free aortic narrowing
This study looks at whether replacing a narrowed heart valve early helps people who have severe aortic stenosis but no symptoms. You would be randomly assigned to early valve replacement or careful waiting with regular check-ups.
Garran, Australian Capital TerritoryAges 18 years+ - NCT04211181Recruiting
Prevent blood clots in hospitalized teens and adults
This study looks at a prevention plan to reduce the risk of hospital-acquired blood clots. It may help people who are expected to stay in the hospital for several days but do not already have a clot.
Beijing, Beijing MunicipalityAges 14 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,982 recruiting cardiology studies from the U.S. registry right now, out of 15,268 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.