Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,609 recruiting studies in this area right now.
By phase
- Not applicable7,632
- Phase 4472
- Phase 2469
- Phase 3439
- Phase 1350
- Phase 1/Phase 2160
- Phase 2/Phase 387
Top conditions
- Stroke797
- Heart Failure534
- Hypertension388
- Cardiovascular Diseases373
- Coronary Artery Disease363
- Multiple Myeloma327
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction97
- Congenital Heart Disease84
- Peripheral Arterial Disease79
- Stroke, Ischemic78
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital68
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California453
- Alabama196
- Arizona181
- Massachusetts173
- New York168
- Florida140
- Texas122
- Maryland118
- Minnesota117
- Illinois112
Recruiting studies9,609 total
- NCT02194816Recruiting
Online survey study for people with Parkinson’s or Parkinsonism
This study looks at how changing certain factors over time relates to symptoms in Parkinson’s disease and related conditions. You may help researchers by completing longer online surveys every 6 months for 5 years.
Kenmore, WashingtonAges 19 years+ - NCT04733404Recruiting
Dragonfly device study for functional mitral valve leakage
This trial tests a catheter-based procedure (putting a small device through blood vessels) to repair a leaking mitral valve caused by heart muscle problems. It aims to reduce symptoms and improve heart function and safety in people who are still having heart failure symptoms despite standard treatment.
Hangzhou, ZhejiangAges 18 years+ - NCT04612322Recruiting
Study registry for microvascular angina patients
This registry study collects information from adults with microvascular angina (chest pain from small blood vessels in the heart). It may help researchers better understand how to assess and manage this condition over time.
Mainz, RLPAges 18–85 - NCT05309343Recruiting
Traditional Chinese medicine study for heart disease patients
This study follows people who are being admitted for heart and blood vessel conditions and records their standard (Western) heart diagnoses. The goal is to describe how traditional Chinese medicine is used for these conditions and what diagnoses the people have.
TianjinAges Any age - NCT05309707Recruiting
Branched stents for certain aortic arch problems
This study looks at using special branched stent-grafts to treat problems in the aortic arch (such as aneurysm or certain tears). It focuses on how well this approach works and how patients do over follow-up visits.
MadridAges 18–90 - NCT02778724Recruiting
Heart catheterization registry for adults who had angioplasty
This study is a national registry that collects information from adults who had a heart catheter test (coronary angiogram) or a procedure to open blocked heart arteries (angioplasty). It helps doctors better understand how these procedures are used and what outcomes patients experience.
Le Coudray, Eure Et LoireAges 18 years+ - NCT05315141Recruiting
Study of AAV in people with ANCA-associated vasculitis
This study follows people with ANCA-associated vasculitis to better understand the treatment using AAV. Your participation would mainly involve agreeing to be in the study and meeting the study’s disease criteria.
Changsha, HunanAges Any age - NCT03372980Recruiting
Study registry of blood tests for Takayasu arteritis
This study collects information and blood samples (biomarkers) to better understand Takayasu arteritis and how active it is. It may help researchers find tests that support diagnosis and track disease activity.
Beijing, Beijing MunicipalityAges 18–70 - NCT04602338Recruiting
Imaging tests to better diagnose heart failure with preserved function
This trial uses several types of heart imaging to diagnose heart failure where squeezing function is still fairly normal. It may help doctors sort out what’s causing your symptoms and guide better care by comparing imaging findings across many patients.
Beijing, Beijing MunicipalityAges Any age - NCT05342233Recruiting
Compare watchful care versus catheter treatment for a bowel artery tear
This study compares two ways to treat an isolated tear in the superior mesenteric artery (a blood vessel that supplies the intestines): conservative (watchful care) versus endovascular (catheter-based) treatment. It may help doctors figure out which approach works best for people whose condition is confirmed on a CT angiogram and who are stable enough for either plan.
Changsha, HunanAges 18 years+ - NCT03972956Recruiting
Collecting samples during cancer or surgery visits
This trial looks at collecting (taking) medical samples from people who need surgery for colorectal cancer, stomach (gastric) cancer, or a non-cancer condition. It may help researchers better understand these diseases and improve how treatment is planned.
Wuhan, HubeiAges 18–80 - NCT03552926Recruiting
Biobank and scan database for recent small stroke patients
This study builds a database and collection (a biobank) from people who recently had a small stroke affecting deep brain areas. It may help researchers better understand small stroke patterns and support future care through better brain imaging and follow-up.
ParisAges 18 years+ - NCT04684602RecruitingPhase 1/Phase 2
Study of stem cells for several short- and long-term illnesses
This early-stage study tests whether injections of mesenchymal stem cells can be safe and helpful for certain chronic (long-term) and acute (short-term) conditions. You might be considered if you can consent, are able to return for follow-up visits, and do not have key reasons that would make stem-cell treatment unsafe.
Culver City, CaliforniaAges 18 years+ - NCT05353946Recruiting
Rotational atherectomy elective vs emergency for heavily calcified blockages
This trial compares doing a special procedure (rotational atherectomy) before an emergency is needed versus using it as a rescue during a heart artery procedure. It is designed for people with very hard, calcified artery blockages and long-term kidney impairment, to see which approach works better and is safer.
MadridAges 18–100 - NCT04393181Recruiting
Study how donor heart function affects transplant outcomes
This study looks at how well donor hearts work and how that affects outcomes after heart transplantation. It may help transplant teams choose and use donor hearts more effectively.
Gothenburg, Västra Götaland CountyAges 18 years+ - NCT05242055Recruiting
Tracking and treating chronic kidney disease risk
This trial looks at how well an integrated program for identifying and treating people at risk for chronic kidney disease (CKD) can improve outcomes. It may help by catching problems earlier and guiding treatment sooner.
Beijing, Beijing MunicipalityAges 18–100 - NCT04804683Recruiting
FMD and SCAD registry study in Europe and beyond
This trial is a registry, meaning it collects detailed medical information to better understand fibromuscular dysplasia (FMD) and a specific type of heart-vessel dissection (SCAD) linked to FMD. It may help researchers learn who is at risk and guide better care in the future.
BrusselsAges Any age - NCT04657861RecruitingEarly Phase 1
BCMA/TACI CAR-T for relapsed or refractory multiple myeloma
This early-phase study tests a CAR-T cell treatment made to target BCMA and TACI proteins in multiple myeloma. It may help people whose myeloma has come back or did not respond to prior treatments, especially after certain prior therapies.
Hangzhou, ZhejiangAges 18–75 - NCT05145517Recruiting
Follow-up study for people who received a JOTEC vascular graft
This study tracks people 18 and older who were treated with a JOTEC vascular graft. It checks how well the graft and follow-up care work over time for certain blood vessel problems.
Münster, North Rhine-WestphaliaAges 18 years+ - NCT04118790Recruiting
MRI study of brain microstructure after stroke
This study uses detailed brain MRI scans to learn how brain tissue changes after stroke or a TIA (a brief stroke-like event). It may help researchers better understand brain recovery and improve future care.
Copenhagen, København NVAges 18 years+ - NCT03479580Recruiting
Registry for coronary and small-vessel heart disease in cardiomyopathy
This study enrolls people with certain types of heart muscle diseases to learn how blocked heart arteries and tiny blood vessels affect symptoms and outcomes. It may help researchers better understand these conditions and improve future care.
La TroncheAges 18–100 - NCT05391815Recruiting
Observational study of endovascular treatment for blocked leg arteries
This is a real-world observational study that follows people who get minimally invasive procedures to treat blocked arteries in the lower abdomen and pelvis. It aims to understand how well these treatments work in the middle and long term.
ShanghaiAges 18–80 - NCT04293471Recruiting
Echocardiogram test to predict outcomes in CRT patients
This trial looks at how well an echocardiogram (ultrasound of the heart) can predict outcomes for people with left bundle branch block who already have cardiac resynchronisation therapy (CRT). If you qualify, your heart scans may be used to better estimate risk and guide care.
Tromsø, TromsAges 18–100 - NCT05311137Recruiting
Closed-loop monitoring for atrial fibrillation
This study tests a “closed-loop” approach to treating atrial fibrillation, meaning the care plan may adjust based on how you’re doing. It may help improve how heart rhythm problems are managed over time.
Shanghai, Shanghai MunicipalityAges 18–100
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,609 recruiting cardiology studies from the U.S. registry right now, out of 14,617 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.