Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,609 recruiting studies in this area right now.
By phase
- Not applicable7,632
- Phase 4472
- Phase 2469
- Phase 3439
- Phase 1350
- Phase 1/Phase 2160
- Phase 2/Phase 387
Top conditions
- Stroke797
- Heart Failure534
- Hypertension388
- Cardiovascular Diseases373
- Coronary Artery Disease363
- Multiple Myeloma327
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction97
- Congenital Heart Disease84
- Peripheral Arterial Disease79
- Stroke, Ischemic78
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital68
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California453
- Alabama196
- Arizona181
- Massachusetts173
- New York168
- Florida140
- Texas122
- Maryland118
- Minnesota117
- Illinois112
Recruiting studies9,609 total
- NCT04544527Recruiting
Study risks for heart disease in older people with diabetes
This study follows older adults with diabetes to understand what factors may raise the risk of heart disease. It may help doctors spot risks earlier in people like you.
Suzhou, JiangsuAges 65–100 - NCT05194423Recruiting
LuX-Valve procedure for severe leaking tricuspid valve
This trial tests a minimally invasive procedure (LuX-Valve placed through a neck vein) to treat severe leaking of the tricuspid valve. It may help people who are too high-risk for open-heart tricuspid surgery.
Beijing, Beijing MunicipalityAges 50 years+ - NCT05208203Recruiting
Registry study for recent stroke and mini-stroke patients
This registry collects information about people recently diagnosed with an acute ischemic stroke or a transient ischemic attack (TIA) at a specific hospital. It helps doctors understand patterns of care and outcomes, which can improve future treatment planning.
Beijing, Beijing MunicipalityAges 18 years+ - NCT02622542Recruiting
Stent repair versus best medical care for type B dissection
This trial compares an endovascular stent (placed through blood vessels) to best medical therapy (blood pressure and pain control) for certain “uncomplicated” type B aortic dissections. It aims to see which approach works better in the early period after symptoms start.
Houston, TexasAges 18 years+ - NCT01566175Recruiting
Neovasc device trial for hard-to-treat chest pain
This trial tests a device called the Neovasc Coronary Sinus Reducer to help people with long-lasting, hard-to-control chest pain (angina) who cannot have artery-opening procedures. It may improve symptoms by changing blood flow in the heart’s vein system.
Tel AvivAges 18 years+ - NCT03142659Recruiting
Heart failure care evaluation for adults at this clinic
This study looks at how people with heart failure are evaluated and managed in the clinic. It mainly involves follow-up care and documenting your treatment plans to improve how care is delivered.
Tel AvivAges 18–120 - NCT02818517Recruiting
Cardio-oncology checkup to understand heart side effects
This study looks at how cancer treatments may affect the heart (“cardiotoxicity”) and how patients are monitored and managed. You might benefit by getting close heart-related follow-up as part of the care plan.
Tel AvivAges 18 years+ - NCT05230446Recruiting
Testing full stent treatment for heart artery blockages
This study looks at how well doctors can treat multiple blocked heart arteries using a specific drug-eluting stent, aiming to fully open them. It may help patients whose blockage pattern fits the study, but it does not include certain high-risk or special cases.
Rotterdam, South HollandAges 18–85 - NCT05238272Recruiting
tRNS device to improve mirror therapy after stroke
This trial tests a brain-stimulation device (tRNS) paired with precision mirror therapy to improve arm movement after a stroke. It may help people with moderate to mild arm weakness regain more control, but you must meet several safety and health criteria.
TaoyuanAges 35–85 - NCT05238610Recruiting
Registry for older adults with stroke of unclear cause and PFO
This study follows adults over 60 who had a stroke where the cause is unclear, and where a heart opening (PFO) may have contributed. It mainly collects information to better understand this stroke pattern and how these patients do over time.
SeoulAges 60 years+ - NCT05250557Recruiting
Study heart blood-flow measurements to predict outcomes in coronary disease
This study looks at a specific heart blood-flow measurement taken during a coronary procedure to see how well it predicts future outcomes. If you had a successful pressure measurement called FFR with a tracing, your results may be analyzed to understand risk and prognosis.
SeoulAges 20 years+ - NCT05257161Recruiting
Carotid stent study comparing two stent positions using brain MRI
This study looks at how well a carotid artery stent works soon after the procedure, using special MRI pictures of the brain. It compares outcomes between stent placement closer to the top versus closer to the bottom of the narrowed area, to see which approach is safer for early brain effects.
NovosibirskAges 45–80 - NCT05250349Recruiting
Ultrasound brain blood flow and thinking in stable heart failure
This trial studies whether a noninvasive ultrasound test of blood flow in the brain, along with memory and thinking questionnaires, can help explain thinking changes in people with stable heart failure. It may help researchers better understand why some people develop cognitive (thinking) difficulties as heart failure progresses.
Krakow, MPAges 18 years+ - NCT05195658Recruiting
Stent vs standard treatment for acute carotid artery stroke
This trial studies whether placing a special device (a micronet-covered stent) can improve treatment of certain acute strokes caused by blockage at the carotid artery “bifurcation” (where the artery splits). It is meant for people who need an urgent, catheter-based procedure to open the blocked vessel.
KrakowAges 18 years+ - NCT04190849Recruiting
Children’s liver fat disease registry in Europe
This is a registry study collecting information about children and teens with fatty liver disease that isn’t caused by alcohol. It aims to better understand this condition and may help future research and treatments.
MaastrichtAges Up to 18 years - NCT05271214Recruiting
Testing conservative care for people with failing heart pumps
This trial is studying a non-surgical (conservative) treatment approach for people being considered for a left ventricular assist device (LVAD). It may help some patients who are too sick or unable to tolerate standard heart failure medicines, but it will only match people with specific heart function and health-test results.
Tel AvivAges 18–80 - NCT05232240Recruiting
Study blood pressure swings after stroke or TIA
This trial studies changes (“swings”) in blood pressure in people who recently had an ischemic stroke or a TIA. It may help doctors understand how blood pressure fluctuations affect recovery, even when you do not have known hypertension.
Beijing, BJAges 18 years+ - NCT05281055Recruiting
Registry of clot-removal treatment for sudden large-vessel strokes
This study keeps a record of people treated with a clot-removal procedure (endovascular thrombectomy) for a sudden stroke caused by a blocked large blood vessel in the brain. It focuses on outcomes for patients who can be treated within 24 hours and were independent before the stroke.
TaipeiAges 20 years+ - NCT05277129Recruiting
Study of the immune response soon after stroke
This study looks at how your body’s immune system reacts in the first hours after a stroke. It may help researchers understand stroke-related immune changes and improve future treatments.
LørenskogAges 18 years+ - NCT05283850RecruitingPhase 2/Phase 3
Study for certain adult cardiac arrest patients
This trial is for adults who have a specific type of cardiac arrest called PEA when EMS arrives. It tests whether the study approach can improve outcomes after this kind of arrest.
Roanoke, VirginiaAges 18 years+ - NCT05283174Recruiting
Blood thinner use during stroke to predict outcomes
This study looks at how people doing well on certain blood thinners do when they have a stroke or bleeding while taking them. It will measure medication levels in your blood to understand stroke severity and recovery in the short and long term.
TaipeiAges 20 years+ - NCT05283603Recruiting
Registry study for people with left bundle branch block
This is an observational registry that collects health information from people who have a heart rhythm pattern called left bundle branch block. It may help doctors better understand causes, outcomes, and care needs for people with this ECG finding.
SassariAges 18 years+ - NCT05283759Recruiting
Brugada syndrome registry study at UZ Brussel
This study keeps a registry (a secure list) of people who have been diagnosed with Brugada syndrome. It helps doctors learn about the condition over time and may support future research aimed at better care.
BrusselsAges 18–100 - NCT05228340Recruiting
Treating toe ulcers by releasing tight tendons to prevent recurrence
This study looks at whether a minor procedure on a toe (called a flexor tenotomy) can reduce the chance that diabetic toe ulcers come back. It is for adults with diabetes who have nerve damage in the feet and have had toe ulcers before.
Amsterdam, North HollandAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,609 recruiting cardiology studies from the U.S. registry right now, out of 14,617 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Pain
- Injuries & trauma
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.