Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,613 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3438
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke796
- Heart Failure535
- Hypertension389
- Cardiovascular Diseases374
- Coronary Artery Disease362
- Multiple Myeloma328
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona182
- Massachusetts174
- New York166
- Florida141
- Texas122
- Maryland118
- Minnesota118
- Illinois111
Recruiting studies9,613 total
- NCT07410117RecruitingPhase 3
Preventing blood clots in advanced solid tumor cancer
This trial tests a new drug called REGN7508 to see if it can prevent dangerous blood clots in people with advanced or metastatic solid tumors. People with a higher risk of clots (based on a simple score or tumor genetics) may qualify.
Hialeah, FloridaAges 18 years+ - NCT07414121Recruiting
Vascular closure vs manual compression after AF ablation
This study compares two methods to close the blood vessel after a catheter ablation for atrial fibrillation (AF). It may help reduce bleeding or other problems at the access site.
HamburgAges 18–95 - NCT07407816Recruiting
Supira heart support device for high-risk artery stenting
This trial tests a new device (the Supira system) that helps support your heart's pumping function during and after a high-risk procedure to open blocked coronary arteries. It is for people with heart failure and complex blockages who may need extra circulatory support.
Tbilisi, K'alak'i T'bilisiAges 18–90 - NCT07414368Enrolling by invitation
StimLabs umbilical cord material for wound healing
This study looks at how a wound treatment made from donated human umbilical cord tissue works for both new and long-lasting wounds. The treatment is a dehydrated powder that is applied directly to the wound.
Bridgeport, ConnecticutAges 18 years+ - NCT06703151Recruiting
Farmers and fishermen with chronic conditions self-care study
This study looks at how well farmers and fishermen manage their own health conditions like high blood pressure, heart disease, high cholesterol, and type 2 diabetes. It aims to understand your awareness, treatment, and ability to practice self-care.
Mailiao, Yun Lin HsienAges 18–75 - NCT07414511Recruiting
Hemophilia A research study for pregnant families
This study follows pregnant people who carry a severe hemophilia A gene and their babies after birth. It looks at how hemophilia A is passed down and how it affects families, with the goal of improving understanding and care.
Seattle, WashingtonAges Any age - NCT07415655RecruitingPhase 2
Albumin for stroke in the front of the brain
This trial tests whether giving albumin (a protein naturally in your blood) can help protect your brain after an ischemic stroke in the front part of your brain. You need to be planning a procedure to open the blocked vessel.
Hradec Králové, Czech RepublicAges 18 years+ - NCT07414446Recruiting
Detecting lung blood flow issues with a new ultrasound device
This trial uses a non-invasive ultrasound device to detect abnormal blood flow connections in the lungs, which are common in people with hereditary hemorrhagic telangiectasia (HHT) or a type of stroke called cryptogenic stroke. The goal is to see if the device can find these issues safely and easily without needing an invasive procedure.
Nieuwegein, UtrechtAges 18 years+ - NCT07410988RecruitingPhase 4
Starch vs. crystalloid fluid for heart surgery patients
This trial compares two types of IV fluids (a starch solution vs. a balanced salt solution) to see which one better protects kidneys after heart surgery. It is for adults having planned heart surgery who do not have severe kidney problems.
DaejeonAges 19 years+ - NCT07409454RecruitingPhase 2
Post-transplant treatment for multiple myeloma with a bispecific antibody
This trial tests a drug that helps your immune system target and kill myeloma cells after a stem cell transplant. It is for people with newly diagnosed multiple myeloma who still have minimal residual disease (small amounts of cancer) after their first transplant.
TianjinAges 18 years+ - NCT07415109Recruiting
Personalized health messages to lower cholesterol
This study tests whether health messages tailored to your personality can help you lower your LDL (bad) cholesterol levels. It is for participants of the RESET study who are at least 21 years old and can communicate in English.
SingaporeAges 21–65 - NCT07411313Recruiting
Ultrasound to predict low blood pressure in older adults having spinal anesthesia
This trial uses ultrasound to check your internal jugular vein, which may help predict if your blood pressure will drop during spinal anesthesia. It aims to find better ways to keep you safe during surgery.
Ankara, YENİMAHALLEAges 65 years+ - NCT07414732Recruiting
Testing a new approach to help stroke survivors take blood pressure pills
This trial tests a simple program to help people who have had a stroke stick with their blood pressure medication. It uses text messages and a medication organizer to make it easier to remember pills and keep blood pressure under control.
Boston, MassachusettsAges 18–99 - NCT07410403Enrolling by invitation
AI study to predict genetic changes in myeloma cells
This trial uses artificial intelligence to look at individual myeloma cells under a microscope to predict genetic abnormalities (FISH results). It may help doctors understand your myeloma better without waiting for a separate FISH test.
Wuhan, HubeiAges Any age - NCT07416279Recruiting
Can tiny bubbles replace catheters for heart pressure checks?
This trial tests if tiny ultrasound contrast bubbles can measure heart pressure, possibly replacing the need for catheter tubes. If you're already getting a heart catheterization, you may be able to join.
LondonAges 21–81 - NCT07410481Recruiting
Therapy for PTSD after a cardiac arrest
This study compares two talking therapies for PTSD after a cardiac arrest. One combines mindfulness and acceptance with gradual exposure to difficult memories; the other focuses on present life challenges. Both aim to reduce distress and improve quality of life.
New York, New YorkAges 18–81 - NCT07411079Recruiting
Testing clot-busting drug on brain bleed blood samples
This study collects blood samples from people with and without bleeding risk to test a clot-dissolving drug (tPA) outside the body. It aims to improve minimally invasive surgery for brain hemorrhages.
LilleAges 18–65 - NCT07412249Recruiting
Arm pressure cuff plus stent for blocked neck arteries
This trial tests if using a blood pressure cuff on the arm (to briefly restrict blood flow) before and after carotid stent placement can help reduce the risk of stroke. It is for people who have recently had stroke symptoms from a moderate to severe carotid artery blockage.
ShenyangAges 40 years+ - NCT07413159Recruiting
Check, monitor, control hypertension study
This 24-month trial tests whether combining pharmacist counseling with community health worker support helps African Americans aged 55+ better control their high blood pressure. You will receive extra guidance to manage your blood pressure at home.
Houston, TexasAges 55 years+ - NCT07413965Recruiting
Transcatheter vs surgical valve replacement for severe bicuspid aortic stenosis
This trial compares two ways to replace a narrowed heart valve in people with a bicuspid aortic valve. If you're 50 or older and need a new valve, this study can help figure out which approach works best.
Los Angeles, CaliforniaAges 50 years+ - NCT07414251Recruiting
Preparing children for heart procedures
This study looks at how children prepare for heart surgery or a heart catheterization. It will ask families to fill out questionnaires to help improve preoperative care.
Berlin, State of BerlinAges Up to 18 years - NCT07410494RecruitingPhase 1/Phase 2
Personalized donor cell therapy for advanced solid tumors
This trial tests a personalized cell therapy (CAR-NK) using donor immune cells that are engineered to find and attack one or two markers on advanced solid tumors. It may be an option for people whose tumors have these specific markers and have exhausted other treatments.
Beijing, Beijing MunicipalityAges 8–85 - NCT07410364Recruiting
CAG and PCI via distal wrist access for small vessels
This trial tests whether a new wrist access point (the distal radial artery) along with specific drug treatments (CAG and PCI) is safe and effective for people with small blood vessels in the heart. It aims to offer an alternative that may reduce bleeding or damage risks.
Changzhou, JiangsuAges 18–85 - NCT07410624Recruiting
Kidney function in brain injury patients
This trial measures how quickly the kidneys clear drugs in patients with serious brain conditions like stroke or meningitis. It may help doctors adjust medicine doses for better treatment.
Lexington, KentuckyAges 18–85
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,613 recruiting cardiology studies from the U.S. registry right now, out of 14,690 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.