Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT05064540Recruiting
Testing a new EVAR approach for unruptured AAA
This trial studies an endovascular (through blood vessels) repair technique for an unruptured enlarged artery in the belly called an abdominal aortic aneurysm (AAA). It may help doctors compare outcomes using a randomized approach and structured follow-up.
Huntsville, AlabamaAges 21 years+ - NCT05064709Recruiting
Test device for heart failure symptoms in some patients
This study tests whether a heart-related device called CCM can improve symptoms and daily function in people with heart failure and a moderately reduced pumping strength. It may help if you’ve had recent heart-failure-related hospital care or urgent treatment and your heart and overall health fit the study limits.
Birmingham, AlabamaAges 18 years+ - NCT05065372RecruitingPhase 1
Metformin test with automated insulin in teens with type 1
This Phase 1 study tests how adding metformin affects blood flow in the kidneys, insulin sensitivity, and overall heart/metabolic health in young people with type 1 diabetes. It may help researchers understand whether this combo is safe and beneficial alongside automated or pump/shot insulin care.
Aurora, ColoradoAges 12–25 - NCT05067231Recruiting
UAB heart research biobank for adults 18 and older
This study builds a heart-focused research database by enrolling adults who are willing to provide information and/or samples for future cardiovascular research. It may help researchers study heart disease and develop better treatments over time.
Birmingham, AlabamaAges 18 years+ - NCT05067998Recruiting
Natural medicine and vitamin IV study for overall health
This study looks at whether natural medicine, vitamin IV fluids, and supplements can help people maintain good health. There don’t appear to be specific eligibility limits listed, so many people may be able to join, but you’d still need screening by the study team.
Dover, DelawareAges 21–80 - NCT05072483Recruiting
Study of CADASIL’s natural course using blood tests and MRI
This study follows people with CADASIL (a genetic brain blood-vessel condition) to learn how it progresses over time. It uses blood and possibly tissue samples and brain MRI scans to better understand changes in the brain.
Bethesda, MarylandAges 18–100 - NCT05074732Recruiting
Study of forensic mental health admissions after a service move
This study looks at all adult admissions to Ireland’s National Forensic Mental Health Service during a specific time window. It may help improve how the new forensic service at Portrane runs in the future.
DublinAges 18 years+ - NCT05078814Recruiting
Survey of a heart and leg condition’s gene differences
This study collects information to understand how often certain genetic variants (ALDH gene family) show up in people with blocked leg arteries or an acute heart condition. The results may help researchers better understand the biology behind these illnesses.
TainanAges 20 years+ - NCT05081713Recruiting
Rehab-based study for walking recovery after a first stroke
This study looks at how therapy and movement training may help people regain walking and compensate after their first stroke. You may be eligible if you are in the early weeks after stroke and are currently in inpatient rehabilitation, with medical clearance to safely participate in exercise.
Indianapolis, IndianaAges 18–85 - NCT05080712Recruiting
Tracking how atrial fibrillation changes over time in young people
This study focuses on people who have atrial fibrillation (an irregular heartbeat) and whose diagnosis was made within the last year. It aims to understand how atrial fibrillation progresses, which could help guide better monitoring and future care.
StockholmAges 18–50 - NCT05081115Recruiting
Stress echo imaging for people with heart valve or muscle issues
This trial studies a stress echocardiogram (an ultrasound of the heart during stress) to better understand and improve future heart imaging. It may help by comparing how well the test works for different heart conditions.
BeneventoAges 18–75 - NCT05085210Recruiting
Brain stimulation to improve parts of lost vision
This study tests whether a noninvasive brain stimulation treatment (tRNS) plus visual training can improve visual field problems after a stroke. It may help some people regain better visual perception in the area they lost.
Boston, MassachusettsAges 18–80 - NCT05089448RecruitingPhase 4
Morning vs bedtime blood pressure medicine dosing study
This trial tests whether taking your blood pressure medicine in the morning or at bedtime controls blood pressure better over a full day and night. It may help certain people find a dosing time that improves nighttime blood pressure.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT05091372RecruitingPhase 2
Maintenance treatment after transplant for newly diagnosed myeloma
This trial tests whether using belantamab mafodotin plus lenalidomide as long-term maintenance after an autologous stem cell transplant can keep multiple myeloma under control, guided by minimal residual disease (MRD). MRD is a very small amount of disease that may remain after transplant, and the study helps see if treating those patients better improves outcomes.
Houston, TexasAges 18 years+ - NCT05093153Recruiting
Registry for adults with IgM blood protein conditions
This study is a registry that collects information about adults with certain IgM-related blood conditions. It may help doctors better understand these illnesses and improve future care.
Mérida, BadajozAges 18 years+ - NCT05093335RecruitingEarly Phase 1
PET scan test for CXCR4 in many relapsed cancers
This early study tests a new PET scan tracer (a radioactive imaging agent) that may light up a cell marker called CXCR4 in certain blood and solid tumor cancers. It may help doctors see where cancers are and how much CXCR4 they have, which could guide future treatments.
New York, New YorkAges 18 years+ - NCT05093764Recruiting
Test how well debris is captured during valve-in-valve TAVR
This trial studies a device and a technique meant to capture debris during a repeat aortic valve procedure (valve-in-valve TAVR). It may help doctors understand if the approach reduces risk from material that can break loose during the procedure.
Kansas City, MissouriAges 18 years+ - NCT05093673Recruiting
Brain stimulation for language recovery after stroke
This study tests whether stimulating the cerebellum can improve word-finding and language skills in people with aphasia after a left-sided stroke. It’s meant for people who are months past their stroke and still have naming difficulties.
Baltimore, MarylandAges 18–99 - NCT05094843Recruiting
Mini-invasive surgery for lung cancer and heart rhythm changes
This study looks at how lung cancer surgery affects the heart’s electrical signals and stress response, using heart tracing tests (ECG) around the time of surgery. It may help doctors better understand and monitor heart risks in people having curative, minimally invasive lung cancer surgery.
Tampere, PirkanmaaAges 18 years+ - NCT05094284Recruiting
Heart stent registry for adults needing coronary stenting
This registry enrolls adults who are about to get a heart stent and have significant blockage in their coronary arteries. It aims to collect real-world information about stenting for different types of heart conditions, which may help improve future care.
Shatin, New TerritoriesAges 18 years+ - NCT05095857RecruitingPhase 4
Ketamine to improve care in severe acute brain injury
This Phase 4 trial tests whether giving ketamine during anesthesia is safe and helpful for adults with severe sudden brain injuries after surgery. It may improve how patients are sedated and cared for while they are on a breathing machine.
CopenhagenAges 18 years+ - NCT05098340Recruiting
Blood RNA test study for new stroke patients
This trial looks at certain molecules in the blood (called circRNA) in people who have a new ischemic stroke (a blockage in a blood vessel). It may help researchers understand what these blood signals mean soon after stroke, which could guide future treatments or monitoring.
Xuzhou, JiangsuAges 18 years+ - NCT05098769Recruiting
Prediction tool for risks after acute pulmonary embolism scans
This trial studies a tool that uses CT scan results and heart blood tests to predict the chance of serious outcomes after an acute pulmonary embolism (a blood clot in the lung). It may help doctors identify higher-risk patients sooner.
Shenyang, LiaoningAges 18 years+ - NCT05099471RecruitingPhase 2
Venetoclax plus rituximab for Waldenström’s macroglobulinemia
This Phase 2 study tests whether the combination of venetoclax and rituximab works better for Waldenström’s macroglobulinemia (WM) than expected from standard approaches. It is for adults with WM who have symptoms or organ/health problems caused by the disease.
BielefeldAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.